The Protective Effects of an Aged Black Garlic Water Extract on the Prostate.
Male
Animals
Plant Extracts
/ pharmacology
Garlic
/ chemistry
Mice, Inbred C57BL
Prostatic Neoplasms
/ drug therapy
Mice
Anti-Inflammatory Agents
/ pharmacology
Humans
Prostate
/ drug effects
Cell Line, Tumor
Cell Proliferation
/ drug effects
Signal Transduction
/ drug effects
Cell Movement
/ drug effects
Inflammation
/ drug therapy
Antioxidants
/ pharmacology
NF-kappa B
/ metabolism
Lipopolysaccharides
Water
/ chemistry
ABGE
cancer
inflammation
prostate
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
07 Sep 2024
07 Sep 2024
Historique:
received:
30
07
2024
revised:
03
09
2024
accepted:
04
09
2024
medline:
14
9
2024
pubmed:
14
9
2024
entrez:
14
9
2024
Statut:
epublish
Résumé
Chronic inflammation is a recognized risk factor for various cancers, including prostate cancer (PCa). We aim to explore the potential protective effects of aged black garlic extract (ABGE) against inflammation-induced prostate damage and its impact on prostate cancer cell lines. We used an ex vivo model of inflammation induced by Escherichia coli lipopolysaccharide (LPS) on C57BL/6 male mouse prostate specimens to investigate the anti-inflammatory properties of ABGE. The gene expression levels of pro-inflammatory biomarkers (
Identifiants
pubmed: 39275340
pii: nu16173025
doi: 10.3390/nu16173025
pii:
doi:
Substances chimiques
Plant Extracts
0
Anti-Inflammatory Agents
0
Antioxidants
0
NF-kappa B
0
Lipopolysaccharides
0
Water
059QF0KO0R
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM