Evaluation of volume measurements of neuroanatomical structures related to speech in multiple sclerosis patients.


Journal

Turkish journal of medical sciences
ISSN: 1303-6165
Titre abrégé: Turk J Med Sci
Pays: Turkey
ID NLM: 9441758

Informations de publication

Date de publication:
2024
Historique:
received: 25 09 2023
revised: 23 08 2024
accepted: 16 07 2024
medline: 19 9 2024
pubmed: 19 9 2024
entrez: 19 9 2024
Statut: epublish

Résumé

Individuals with multiple sclerosis (MS) may experience various speech-related issues, including decreased speech rate, increased pauses, and changes in speech rhythms. The purpose of this study was to compare the volumes of speech-related neuroanatomical structures in MS patients with those in a control group. The research was conducted in the Neurology and Radiology Departments of Malatya Training and Research Hospital. The records of patients who presented to the Neurology Department between 2019 and 2022 were examined. The study included the magnetic resonance imaging (MRI) findings of 100 individuals, with 50 in the control group and 50 patients with MS, who had applied to the hospital in the specified years. VolBrain is a free system that works automatically over the internet (http://volbrain.upv.es/), enabling the measurement of brain volumes without human interaction. The acquired images were analyzed using the VolBrain program. As a result of our research, a significant decrease was found in the volume of 18 of 26 speech-related regions in MS patients. It was determined that whole brain volumes decreased in the MS group compared to the control group. In our study, volume measurements of more speech-related areas were performed, unlike the few related studies previously conducted. We observed significant atrophy findings in the speech-related areas of the frontal, temporal, and parietal lobes of MS patients.

Sections du résumé

Background/aim UNASSIGNED
Individuals with multiple sclerosis (MS) may experience various speech-related issues, including decreased speech rate, increased pauses, and changes in speech rhythms. The purpose of this study was to compare the volumes of speech-related neuroanatomical structures in MS patients with those in a control group.
Materials and methods UNASSIGNED
The research was conducted in the Neurology and Radiology Departments of Malatya Training and Research Hospital. The records of patients who presented to the Neurology Department between 2019 and 2022 were examined. The study included the magnetic resonance imaging (MRI) findings of 100 individuals, with 50 in the control group and 50 patients with MS, who had applied to the hospital in the specified years. VolBrain is a free system that works automatically over the internet (http://volbrain.upv.es/), enabling the measurement of brain volumes without human interaction. The acquired images were analyzed using the VolBrain program.
Results UNASSIGNED
As a result of our research, a significant decrease was found in the volume of 18 of 26 speech-related regions in MS patients. It was determined that whole brain volumes decreased in the MS group compared to the control group.
Conclusion UNASSIGNED
In our study, volume measurements of more speech-related areas were performed, unlike the few related studies previously conducted. We observed significant atrophy findings in the speech-related areas of the frontal, temporal, and parietal lobes of MS patients.

Identifiants

pubmed: 39295620
doi: 10.55730/1300-0144.5839
pii: tjmed-54-04-700
pmc: PMC11407364
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

700-709

Informations de copyright

© TÜBİTAK.

Déclaration de conflit d'intérêts

Declarations: The authors declare no conflict of interest, financial or otherwise. This study has no financial resources and no sponsors.

Auteurs

Hıdır Pekmez (H)

Division of Anatomy, Department of Basic Medical Sciences, Faculty of Medicine, Malatya Turgut Özal University, Malatya, Turkiye.

Anıl Altiparmak (A)

Division of Anatomy, Department of Basic Medical Sciences, Institute of Graduate Science, Malatya Turgut Özal University, Malatya, Turkiye.

Feyza Inceoğlu (F)

Division of Biostatistics, Department of Basic Medical Sciences, Faculty of Medicine, Malatya Turgut Özal University, Malatya, Turkiye.

Mehmet Akçiçek (M)

Division of Radiology, Department of Internal Medicine, Faculty of Medicine, Malatya Turgut Özal University, Malatya, Turkiye.

Aslı Bolayir (A)

Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Malatya Turgut Özal University, Malatya, Turkiye.

Zeynep Özbay (Z)

Division of Anatomy, Department of Basic Medical Sciences, Institute of Graduate Science, Malatya Turgut Özal University, Malatya, Turkiye.

Merve Aydin (M)

Division of Anatomy, Department of Basic Medical Sciences, Faculty of Medicine, Malatya Turgut Özal University, Malatya, Turkiye.

Muhammed Furkan Arpaci (MF)

Division of Anatomy, Department of Basic Medical Sciences, Faculty of Medicine, Malatya Turgut Özal University, Malatya, Turkiye.

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