Focus on fungi.

Fungi / pathogenicity Humans Mycoses / microbiology Animals Drug Resistance, Fungal Antifungal Agents / pharmacology Virulence

Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
19 Sep 2024
Historique:
received: 10 06 2024
revised: 01 08 2024
accepted: 07 08 2024
medline: 21 9 2024
pubmed: 21 9 2024
entrez: 20 9 2024
Statut: ppublish

Résumé

Fungi play critical roles in the homeostasis of ecosystems globally and have emerged as significant causes of an expanding repertoire of devastating diseases in plants, animals, and humans. In this Commentary, we highlight the importance of fungal pathogens and argue for concerted research efforts to enhance understanding of fungal virulence, antifungal immunity, novel drug targets, antifungal resistance, and the mycobiota to improve human health.

Identifiants

DOI: 10.1016/j.cell.2024.08.016 PMID: 39303681
pubmed: 39303681
pii: S0092-8674(24)00907-3
doi: 10.1016/j.cell.2024.08.016
pii:
doi:

Substances chimiques

Antifungal Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

5121-5127

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Iliyan D Iliev (ID)

Joan and Sanford I. Weill Department of Medicine, The Jill Roberts Institute for Research in Inflammatory Bowel Disease, and Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA. Electronic address: iliev@med.cornell.edu.

Gordon D Brown (GD)

MRC Centre for Medical Mycology at the University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter EX4 4QD, UK.

Petra Bacher (P)

Institute of Immunology and Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.

Sarah L Gaffen (SL)

Division of Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.

Joseph Heitman (J)

Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.

Bruce S Klein (BS)

Departments of Pediatrics, Medicine, and Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA.

Michail S Lionakis (MS)

Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Focus on fungi.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Focus on fungi.
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Mycoses › Focus on fungi.
questionsmedicales.fr › Eucaryotes › Animaux › Focus on fungi.
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance microbienne aux médicaments › Résistance des champignons aux médicaments › Focus on fungi.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antifongiques › Focus on fungi.
questionsmedicales.fr › Phénomènes microbiologiques › Virulence › Focus on fungi.