Dose advantage of abdominal deep inspiratory breath-hold (aDIBH) in postoperative adjuvant radiotherapy for left breast cancer.
Humans
Female
Radiotherapy, Adjuvant
/ methods
Middle Aged
Breath Holding
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
/ methods
Unilateral Breast Neoplasms
/ radiotherapy
Organs at Risk
/ radiation effects
Adult
Breast Neoplasms
/ radiotherapy
Mastectomy, Segmental
Aged
Heart
/ radiation effects
Tomography, X-Ray Computed
Lung
/ radiation effects
Inhalation
Abdominal deep inspiration breath-hold
Breast cancer
Dosimetry
Radiotherapy
Journal
Journal of the Egyptian National Cancer Institute
ISSN: 2589-0409
Titre abrégé: J Egypt Natl Canc Inst
Pays: England
ID NLM: 9424566
Informations de publication
Date de publication:
23 Sep 2024
23 Sep 2024
Historique:
received:
12
05
2024
accepted:
21
08
2024
medline:
23
9
2024
pubmed:
23
9
2024
entrez:
22
9
2024
Statut:
epublish
Résumé
We explored the dosimetric efficacy of the abdominal deep inspiration breath hold (aDIBH) technique using an audio-guided device in patients with left breast cancer undergoing postoperative adjuvant radiotherapy compared to free breathing (FB). A total of 35 patients with early stage left breast cancer underwent two computed tomography simulation scans each with aDIBH and FB after breast-conserving surgery. Treatment planning was optimized using the Pinnacle Compared with FB, the heart moved farther caudally and away from the chest wall, and the volume of heart became smaller under aDIBH due to expansion of the lungs. The D mean of the heart, LADCA and left lung of aDIBH were respectively reduced by 332.79 ± 264.61 cGy (P < 0.001), 1290.37 ± 612.09 cGy (P < 0.047) and 69.94 ± 117.73 cGy (P < 0.001). The V20 and V30 of the OARs were also significantly reduced with statistical differences (P < 0.05). In addition, there was no significant difference in the dosimetric parameters of the PTV between the two groups (P > 0.05). Implementation of the aDIBH technique for postoperative radiotherapy after breast-conserving surgery of the left breast cancer could reduce irradiation of the heart dose, LADCA dose and left lung dose, without compromising target coverage.
Identifiants
pubmed: 39307905
doi: 10.1186/s43046-024-00234-2
pii: 10.1186/s43046-024-00234-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
29Informations de copyright
© 2024. The Author(s).
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