Magnetic resonance diffusion-weighted imaging in lacrimal gland lymphoma versus inflammation: A comparative study.
Humans
Female
Diffusion Magnetic Resonance Imaging
/ methods
Middle Aged
Retrospective Studies
Male
Lacrimal Apparatus
/ diagnostic imaging
Adult
Diagnosis, Differential
Lymphoma
/ diagnosis
Aged
Eye Neoplasms
/ diagnosis
Lacrimal Apparatus Diseases
/ diagnosis
Biopsy
Dacryocystitis
/ diagnosis
Young Adult
Inflammation
/ diagnosis
Adolescent
Journal
Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376
Informations de publication
Date de publication:
01 Oct 2024
01 Oct 2024
Historique:
received:
07
08
2023
accepted:
08
04
2024
medline:
27
9
2024
pubmed:
27
9
2024
entrez:
27
9
2024
Statut:
ppublish
Résumé
To determine the role of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) in differentiating the inflammatory process and malignant lymphoma of the lacrimal gland. A retrospective analysis of all subjects who underwent lacrimal gland biopsy and magnetic resonance (MR) imaging with DWI sequences during a 10-year period at the Sheba Medical Center, Israel. The lacrimal glands' ADC values were documented bilaterally by blinded observers and correlated with the final histology verified diagnoses. Twenty-eight patients were included, with 19 females (68%) with a mean ± SD age of 48.1 ± 25.7 years. The right orbit was involved in 14 cases (50%) and the left in 13 (46%); one patient (4%) had bilateral involvement. Seventeen cases (61%) had a final diagnosis of idiopathic inflammation or dacryoadenitis, and six cases (21%) were diagnosed with lymphoma. Additional diagnoses included pleomorphic adenoma in 3 (11%), adenoid cystic carcinoma, and solitary fibrous tumor. Lower mean ADC values were observed in the lymphoma versus inflammatory group (1.03 × 10-3 Vs. 1.45 × 10-3, P = 0.02). Restricted diffusion on MR imaging can serve as a diagnostic tool in the differentiation between inflammatory processes of the lacrimal gland and lymphoma.
Identifiants
pubmed: 39331435
doi: 10.4103/IJO.IJO_2109_23
pii: 02223307-202472100-00013
doi:
Types de publication
Journal Article
Comparative Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1448-1452Informations de copyright
Copyright © 2024 Copyright: © 2024 Indian Journal of Ophthalmology.
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