Twin study identifies early immunological and metabolic dysregulation of CD8

CD8-Positive T-Lymphocytes / immunology Humans Multiple Sclerosis / immunology Female Male Adult Twins, Monozygotic Middle Aged Single-Cell Analysis

Journal

Science immunology
ISSN: 2470-9468
Titre abrégé: Sci Immunol
Pays: United States
ID NLM: 101688624

Informations de publication

Date de publication:
27 Sep 2024
Historique:
medline: 27 9 2024
pubmed: 27 9 2024
entrez: 27 9 2024
Statut: ppublish

Résumé

Multiple sclerosis (MS) is an inflammatory neurological disease of the central nervous system with a subclinical phase preceding frank neuroinflammation. CD8 Proinflammatory features of CD8

Autres résumés

Type: Publisher (ger)
Proinflammatory features of CD8

Identifiants

DOI: 10.1126/sciimmunol.adj8094 PMID: 39331727
pubmed: 39331727
doi: 10.1126/sciimmunol.adj8094
doi:

Types de publication

Journal Article Twin Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadj8094

Auteurs

Vladyslav Kavaka (V)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
ORCID: 0009-0004-5837-3384

Luisa Mutschler (L)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.

Clara de la Rosa Del Val (C)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Graduate School of Systemic Neurosciences, Ludwig Maximilian University of Munich, Munich, Germany.
ORCID: 0000-0002-1344-0844

Klara Eglseer (K)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.

Ana M Gómez Martínez (AM)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.

Andrea Flierl-Hecht (A)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
ORCID: 0000-0002-2359-1128

Birgit Ertl-Wagner (B)

Department of Radiology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Department of Medical Imaging, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
ORCID: 0000-0002-7896-7049

Daniel Keeser (D)

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
ORCID: 0000-0002-0244-1024

Martin Mortazavi (M)

Department of Radiology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Department of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
ORCID: 0000-0002-0826-7661

Klaus Seelos (K)

Institute of Neuroradiology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
ORCID: 0009-0009-0350-1293

Hanna Zimmermann (H)

Institute of Neuroradiology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
ORCID: 0000-0002-1476-3477

Jürgen Haas (J)

Molecular Neuroimmunology Group, Department of Neurology, University of Heidelberg, Heidelberg, Germany.
ORCID: 0000-0002-2314-7465

Brigitte Wildemann (B)

Molecular Neuroimmunology Group, Department of Neurology, University of Heidelberg, Heidelberg, Germany.
ORCID: 0000-0002-5389-3338

Tania Kümpfel (T)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
ORCID: 0000-0001-7509-5268

Klaus Dornmair (K)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
ORCID: 0000-0003-0342-5373

Thomas Korn (T)

Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
Institute for Experimental Neuroimmunology, Technical University of Munich School of Medicine, Munich, Germany.
Department of Neurology, Technical University of Munich School of Medicine, Munich, Germany.
ORCID: 0000-0002-3633-0955

Reinhard Hohlfeld (R)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
ORCID: 0000-0002-6302-1488

Martin Kerschensteiner (M)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
ORCID: 0000-0003-4898-9383

Lisa Ann Gerdes (LA)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
ORCID: 0000-0002-7053-3924

Eduardo Beltrán (E)

Institute of Clinical Neuroimmunology, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.
Biomedical Center (BMC), Faculty of Medicine, Ludwig Maximilian University of Munich, Martinsried, Germany.
Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.
ORCID: 0000-0002-7266-4098

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD8+ › Twin study identifies early immunological and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Twin study identifies early immunological and...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Maladies auto-immunes du système nerveux › Maladies démyélinisantes auto-immunes du SNC › Sclérose en plaques › Twin study identifies early immunological and...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Twin study identifies early immunological and...
questionsmedicales.fr › Personnes › Progéniture de naissance multiple › Jumeaux › Jumeaux monozygotes › Twin study identifies early immunological and...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Twin study identifies early immunological and...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Analyse sur cellule unique › Twin study identifies early immunological and...