Are Melanocortin Receptors Present in Extant Protochordates?

Animals Humans Receptors, Melanocortin / metabolism HEK293 Cells Phylogeny Cyclic AMP / metabolism Amino Acid Sequence Ciona intestinalis / genetics Urochordata / genetics
G protein-coupled receptor cephalochordate chordates constitutive activity evolution melanocortin receptor urochordata

Journal

Biomolecules
ISSN: 2218-273X
Titre abrégé: Biomolecules
Pays: Switzerland
ID NLM: 101596414

Informations de publication

Date de publication:
04 Sep 2024
Historique:
received: 03 08 2024
revised: 02 09 2024
accepted: 03 09 2024
medline: 28 9 2024
pubmed: 28 9 2024
entrez: 28 9 2024
Statut: epublish

Résumé

Functional melanocortin receptor (MCR) genes have been identified in the genomes of early chordates, e.g., the cyclostomata. Whether they appear in the most ancient chordates such as cephalochordate and urochordata, however, remains unclear due to missing genetic data. Herein, we studied five putative (from NCBI database), sequence-based predicted MCR-like receptors from urochordata and cephalochordate, including

Identifiants

DOI: 10.3390/biom14091120 PMID: 39334886
pubmed: 39334886
pii: biom14091120
doi: 10.3390/biom14091120
pii:
doi:

Substances chimiques

Receptors, Melanocortin 0
Cyclic AMP E0399OZS9N

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : SFB1423

Auteurs

Ren-Lei Ji (RL)

Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.

Shan-Shan Jiang (SS)

Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.

Gunnar Kleinau (G)

Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Structural Biology of Cellular Signaling, D-10117 Berlin, Germany.

Patrick Scheerer (P)

Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Structural Biology of Cellular Signaling, D-10117 Berlin, Germany.
ORCID: 0000-0001-5028-2075

Ya-Xiong Tao (YX)

Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
ORCID: 0000-0003-4737-749X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur hormone hypophysaire › Récepteur corticotrophine › Récepteurs à la mélanocortine › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Sciences de l'information › Phylogenèse › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › AMP cyclique › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Chordés invertébrés › Urochordata › Ciona › Ciona intestinalis › Are Melanocortin Receptors Present in Extant...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Chordés invertébrés › Urochordata › Are Melanocortin Receptors Present in Extant...