Deep Intraclonal Analysis for the Development of Vaccines against Drug-Resistant

Klebsiella pneumoniae / immunology Bacterial Vaccines / immunology Humans Klebsiella Infections / prevention & control Drug Resistance, Multiple, Bacterial / genetics Antigens, Bacterial / immunology Vaccine Development Bacterial Proteins / immunology Epitopes, B-Lymphocyte / immunology
antibiotic resistance betweenness centrality epitope immunoinformatics intrahospital infection natural processing language neutralizing antibody protein hub reverse vaccinology virulence factor

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
11 Sep 2024
Historique:
received: 20 08 2024
revised: 05 09 2024
accepted: 08 09 2024
medline: 29 9 2024
pubmed: 28 9 2024
entrez: 28 9 2024
Statut: epublish

Résumé

Despite its medical relevance, there is no commercial vaccine that protects the population at risk from multidrug-resistant (MDR)

Identifiants

DOI: 10.3390/ijms25189837 PMID: 39337325
pubmed: 39337325
pii: ijms25189837
doi: 10.3390/ijms25189837
pii:
doi:

Substances chimiques

Bacterial Vaccines 0
Antigens, Bacterial 0
Bacterial Proteins 0
Epitopes, B-Lymphocyte 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Instituto de Salud Carlos III
ID : MPY 509/19
Organisme : Instituto de Salud Carlos III
ID : MPY 227/23
Organisme : Instituto de Salud Carlos III
ID : PMP22/00092

Auteurs

Ana Tajuelo (A)

Intrahospital Infections Unit, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Universidad Nacional de Educación a Distancia (UNED), 28015 Madrid, Spain.

Eva Gato (E)

Intrahospital Infections Unit, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
ORCID: 0000-0002-1662-514X

Jesús Oteo-Iglesias (J)

Reference and Research Laboratory for Antibiotic Resistance and Health Care Infections, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.
ORCID: 0000-0003-3327-8263

María Pérez-Vázquez (M)

Reference and Research Laboratory for Antibiotic Resistance and Health Care Infections, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), 28029 Madrid, Spain.

Michael J McConnell (MJ)

Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.

Antonio J Martín-Galiano (AJ)

Core Scientific and Technical Units, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.

Astrid Pérez (A)

Intrahospital Infections Unit, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
ORCID: 0000-0003-1809-3332

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Classifications MeSH

questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Klebsiella › Klebsiella pneumoniae › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins antibactériens › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Infections bactériennes › Infections bactériennes à Gram négatif › Infections à Enterobacteriaceae › Infections à Klebsiella › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Multirésistance aux médicaments › Multirésistance bactérienne aux médicaments › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes bactériens › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Techniques d'investigation › Développement de vaccin › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Deep Intraclonal Analysis for the Development...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Déterminants antigéniques des lymphocytes B › Deep Intraclonal Analysis for the Development...