Calcium-Dependent Chemiluminescence Catalyzed by a Truncated c-MYC Promoter G-Triplex DNA.

Promoter Regions, Genetic Calcium / metabolism DNA, Catalytic / chemistry DNA / chemistry Luminescence Catalysis Proto-Oncogene Proteins c-myc / genetics G-Quadruplexes Circular Dichroism Humans Luminol / chemistry Oxidation-Reduction Hemin / chemistry Nucleic Acid Conformation
G-triplex DNA chemiluminescence peroxidase

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
20 Sep 2024
Historique:
received: 12 08 2024
revised: 13 09 2024
accepted: 16 09 2024
medline: 29 9 2024
pubmed: 28 9 2024
entrez: 28 9 2024
Statut: epublish

Résumé

The dynamic landscape of non-canonical DNA G-quadruplex (G4) folding into G-triplex intermediates has led to the study of G-triplex structures and their ability to serve as peroxidase-mimetic DNAzymes. Here we report the formation, stability, and catalytic activity of a 5'-truncated

Identifiants

DOI: 10.3390/molecules29184457 PMID: 39339453
pubmed: 39339453
pii: molecules29184457
doi: 10.3390/molecules29184457
pii:
doi:

Substances chimiques

Calcium SY7Q814VUP
DNA, Catalytic 0
DNA 9007-49-2
triplex DNA 0
Proto-Oncogene Proteins c-myc 0
Luminol 5EXP385Q4F
Hemin 743LRP9S7N

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIH HHS
ID : 1R25GM102783-04A1
Pays : United States

Auteurs

Malay Kumar Das (MK)

Materials Science, Engineering, and Commercialization Program, Texas State University, San Marcos, TX 78666, USA.

Elizabeth P Williams (EP)

Department of Chemistry & Biochemistry, Texas State University, San Marcos, TX 78666, USA.

Mitchell W Myhre (MW)

Department of Chemistry & Biochemistry, Texas State University, San Marcos, TX 78666, USA.

Wendi M David (WM)

Department of Chemistry & Biochemistry, Texas State University, San Marcos, TX 78666, USA.

Sean M Kerwin (SM)

Materials Science, Engineering, and Commercialization Program, Texas State University, San Marcos, TX 78666, USA.
Department of Chemistry & Biochemistry, Texas State University, San Marcos, TX 78666, USA.
ORCID: 0000-0001-8432-6558

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Éléments de régulation transcriptionnelle › Régions promotrices (génétique) › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › ADN catalytique › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Phénomènes physiques › Rayonnement › Rayonnement non ionisant › Lumière › Luminescence › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Phénomènes chimiques › Catalyse › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription à motif basique hélice-boucle-hélice › Protéines proto-oncogènes c-myc › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › G-quadruplexes › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Dichroïsme circulaire › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyridazines › Luminol › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Métabolisme › Métabolisme énergétique › Oxydoréduction › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Porphyrines › Métalloporphyrines › Hème › Hémine › Calcium-Dependent Chemiluminescence Catalyzed...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › Calcium-Dependent Chemiluminescence Catalyzed...