Risk analysis of postoperative nausea and vomiting in patients after gynecologic laparoscopic surgery.
Humans
Postoperative Nausea and Vomiting
/ epidemiology
Laparoscopy
/ adverse effects
Female
Gynecologic Surgical Procedures
/ adverse effects
Retrospective Studies
Middle Aged
Adult
Risk Factors
Risk Assessment
/ methods
Nomograms
Sufentanil
/ administration & dosage
Remifentanil
/ administration & dosage
Analgesia, Patient-Controlled
Neostigmine
/ administration & dosage
Machine Learning
Analgesics, Opioid
/ administration & dosage
Gynecologic surgery
Laparoscopic surgery
Nomogram
Postoperative nausea and vomiting
Journal
BMC anesthesiology
ISSN: 1471-2253
Titre abrégé: BMC Anesthesiol
Pays: England
ID NLM: 100968535
Informations de publication
Date de publication:
28 Sep 2024
28 Sep 2024
Historique:
received:
07
10
2023
accepted:
12
09
2024
medline:
29
9
2024
pubmed:
29
9
2024
entrez:
28
9
2024
Statut:
epublish
Résumé
This study is designed to identify risk factors of postoperative nausea and vomiting (PONV) in patients after gynecologic laparoscopic surgery and establish a nomogram model. In this retrospective and multicenter study, we collected and analyzed data from 1233 patients who underwent gynecologic laparoscopic surgery. The Lasso algorithm was used to optimize the selection of independent variables in the development group. Multivariate logistic regression analysis was used to explore the risk factors of PONV to develop the predictive nomogram model. Finally, we used an internal and external verification group and machine learning (ML) to evaluate the accuracy and clinical applicability of the model. The dosage of sufentanil in patient-controlled intravenous analgesia (PCIA), the dosage of remifentanil, the use of neostigmine, duration of surgery and the maximum value of the P A nomogram model was developed to predict the incidence of PONV in patients after gynecologic laparoscopic surgery. This model was found to be reliable and of high clinical value.
Identifiants
pubmed: 39342087
doi: 10.1186/s12871-024-02727-y
pii: 10.1186/s12871-024-02727-y
doi:
Substances chimiques
Sufentanil
AFE2YW0IIZ
Remifentanil
P10582JYYK
Neostigmine
3982TWQ96G
Analgesics, Opioid
0
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
345Subventions
Organisme : National Natural Science Foundation of China
ID : 81870879
Organisme : Natural Science Foundation of Guangdong Province
ID : 2017A030313534
Organisme : Guangzhou Key Laboratory of Neuropathic Pain Mechanism at Spinal Cord Level
ID : 202102100005
Informations de copyright
© 2024. The Author(s).
Références
Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validations between two centers. Anesthesiology. 1999;91(3):693–700.
doi: 10.1097/00000542-199909000-00022
pubmed: 10485781
Ku CM, Ong BC. Postoperative nausea and vomiting: a review of current literature. Singap Med J. 2003;44(7):366–74.
Gan T, Sloan F, Dear GL, El-Moalem HE, Lubarsky DA. How much are patients willing to pay to avoid postoperative nausea and vomiting? Anesth Analg. 2001;92(2):393–400.
doi: 10.1213/00000539-200102000-00022
pubmed: 11159239
van Wijk MG, Smalhout B. A postoperative analysis of the patient’s view of anaesthesia in a Netherlands’ teaching hospital. Anaesthesia. 1990;45(8):679–82.
doi: 10.1111/j.1365-2044.1990.tb14399.x
pubmed: 2400083
Boza A, Urman B, Vatansever D, Ceyhan M, Mısırlıoglu S, Koca S, Çapraz K, Tunga Dogan A, Taskıran C. Mini-laparoscopic gynecological surgery using smaller ports minimizes Incisional Pain and postoperative scar size: a paired sample analysis. Surg Innov. 2020;27(5):455–60.
doi: 10.1177/1553350620923526
pubmed: 32501743
van den Bosch JE, Kalkman CJ, Vergouwe Y, Van Klei WA, Bonsel GJ, Grobbee DE, Moons KGM. Assessing the applicability of scoring systems for predicting postoperative nausea and vomiting. Anaesthesia. 2005;60(4):323–31.
doi: 10.1111/j.1365-2044.2005.04121.x
pubmed: 15766334
Chae D, Kim SY, Song Y, Baek W, Shin H, Park K, Han DW. Dynamic predictive model for postoperative nausea and vomiting for intravenous fentanyl patient-controlled analgesia. Anaesthesia. 2020;75(2):218–26.
doi: 10.1111/anae.14849
pubmed: 31531854
Park SY. Nomogram: an analogue tool to deliver digital knowledge. J Thorac Cardiovasc Surg. 2018;155(4):1793.
doi: 10.1016/j.jtcvs.2017.12.107
pubmed: 29370910
Sauerbrei W, Royston P, Binder H. Selection of important variables and determination of functional form for continuous predictors in multivariable model building. Stat Med. 2007;26(30):5512–28.
doi: 10.1002/sim.3148
pubmed: 18058845
Friedman J, Hastie T, Tibshirani R. Regularization paths for generalized Linear models via Coordinate Descent. J Stat Softw 2010, 33(1).
Harrell FE, Lee KL, Mark DB. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med. 1996;15(4):361–87.
doi: 10.1002/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4
pubmed: 8668867
Vasileiou I, Xanthos T, Koudouna E, Perrea D, Klonaris C, Katsargyris A, Papadimitriou L. Propofol: a review of its non-anaesthetic effects. Eur J Pharmacol. 2009;605(1–3):1–8.
doi: 10.1016/j.ejphar.2009.01.007
pubmed: 19248246
Sinclair DR, Chung F, Mezei G. Can postoperative nausea and vomiting be predicted? Anesthesiology. 1999;91(1):109–18.
Awad K, Ahmed H, Abushouk AI, Al Nahrawi S, Elsherbeny MY, Mustafa SM, Attia A. Dexamethasone combined with other antiemetics versus single antiemetics for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: an updated systematic review and meta-analysis. Int J Surg. 2016;36(Pt A):152–63.
doi: 10.1016/j.ijsu.2016.10.034
pubmed: 27793640
Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, Jin Z, Kovac AL, Meyer TA, Urman RD, et al. Fourth Consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg. 2020;131(2):411–48.
doi: 10.1213/ANE.0000000000004833
pubmed: 32467512
Hood DD, Eisenach JC, Tuttle R. Phase I safety assessment of intrathecal neostigmine methylsulfate in humans. Anesthesiology. 1995;82(2):331–43.
doi: 10.1097/00000542-199502000-00003
pubmed: 7856891
Cheng C-R, Sessler DI, Apfel CC. Does neostigmine administration produce a clinically important increase in postoperative nausea and vomiting? Anesth Analg. 2005;101(5):1349–55.
doi: 10.1213/01.ANE.0000180992.76743.C9
pubmed: 16243993
pmcid: 1458621
Besir A, Tugcugil E. Comparison of different end-tidal carbon dioxide levels in preventing postoperative nausea and vomiting in gynaecological patients undergoing laparoscopic surgery. J Obstet Gynaecol. 2021;41(5):755–62.
doi: 10.1080/01443615.2020.1789961
pubmed: 33045886
Son J-S, Oh J-Y, Ko S. Effects of hypercapnia on postoperative nausea and vomiting after laparoscopic surgery: a double-blind randomized controlled study. Surg Endosc. 2017;31(11):4576–82.
doi: 10.1007/s00464-017-5519-8
pubmed: 28389799
Dong L, Takeda C, Yamazaki H, Hamada M, Hirotsu A, Yamamoto Y, Mizota T. Association between intraoperative end-tidal carbon dioxide and postoperative nausea and vomiting in gynecologic laparoscopic surgery. Sci Rep. 2022;12(1):6865.
doi: 10.1038/s41598-022-10727-6
pubmed: 35477978
pmcid: 9046149