Docetaxel-tethered di-Carboxylic Acid Derivatised Fullerenes: A Promising Drug Delivery Approach for Breast Cancer.
Fullerenes
/ chemistry
Docetaxel
/ administration & dosage
Breast Neoplasms
/ drug therapy
Humans
Female
Antineoplastic Agents
/ administration & dosage
Animals
Cell Survival
/ drug effects
Drug Delivery Systems
/ methods
Carboxylic Acids
/ chemistry
Particle Size
Drug Carriers
/ chemistry
Cell Line, Tumor
Drug Liberation
Nanoconjugates
/ chemistry
Rats
MCF-7 Cells
Biological Availability
anti-cancer
bioavailability
biocompatibility
drug conjugation
drug delivery
fullerenes
hydrophilic linker
Journal
AAPS PharmSciTech
ISSN: 1530-9932
Titre abrégé: AAPS PharmSciTech
Pays: United States
ID NLM: 100960111
Informations de publication
Date de publication:
02 Oct 2024
02 Oct 2024
Historique:
received:
24
04
2024
accepted:
23
09
2024
medline:
3
10
2024
pubmed:
3
10
2024
entrez:
2
10
2024
Statut:
epublish
Résumé
Docetaxel (DTX) has become widely accepted as a first-line treatment for metastatic breast cancer; however, the frequent development of resistance provides challenges in treating the disease.C
Identifiants
pubmed: 39358486
doi: 10.1208/s12249-024-02955-y
pii: 10.1208/s12249-024-02955-y
doi:
Substances chimiques
Fullerenes
0
Docetaxel
15H5577CQD
Antineoplastic Agents
0
Carboxylic Acids
0
Drug Carriers
0
Nanoconjugates
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
233Informations de copyright
© 2024. The Author(s), under exclusive licence to American Association of Pharmaceutical Scientists.
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