Assessing the repeatability of expiratory flow limitation during incremental exercise in healthy adults.


Journal

Physiological reports
ISSN: 2051-817X
Titre abrégé: Physiol Rep
Pays: United States
ID NLM: 101607800

Informations de publication

Date de publication:
Oct 2024
Historique:
revised: 23 08 2024
received: 08 05 2024
accepted: 15 09 2024
medline: 3 10 2024
pubmed: 3 10 2024
entrez: 3 10 2024
Statut: ppublish

Résumé

We sought to determine the repeatability of EFL in healthy adults during incremental cycle exercise. We hypothesized that the repeatability of EFL would be "strong" when assessed as a binary variable (i.e., absent or present) but "poor" when assessed as a continuous variable (i.e., % tidal volume overlap). Thirty-two healthy adults performed spirometry and an incremental cycle exercise test to exhaustion on two occasions. Standard cardiorespiratory variables were measured at rest and throughout exercise, and EFL was assessed by overlaying tidal expiratory flow-volume and maximal expiratory flow-volume curves. The repeatability of EFL was determined using Cohen's κ for binary assessments of EFL and intraclass correlation (ICC) for continuous measures of EFL. During exercise, n = 12 participants (38%) experienced EFL. At peak exercise, the repeatability of EFL was "minimal" (κ = 0.337, p = 0.145) when assessed as a binary variable and "poor" when measured as a continuous variable (ICC = 0.338, p = 0.025). At matched levels of minute ventilation during high-intensity exercise (i.e., >75% of peak oxygen uptake), the repeatability of EFL was "weak" when measured as a binary variable (κ = 0.474, p = 0.001) and "moderate" when measured as a continuous variable (ICC = 0.603, p < 0.001). Our results highlight the day-to-day variability associated with assessing EFL during exercise in healthy adults.

Identifiants

pubmed: 39358859
doi: 10.14814/phy2.70068
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e70068

Subventions

Organisme : Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (NSERC)
ID : RGPIN-2020-06564
Organisme : Research Manitoba (RM)
ID : 5409

Informations de copyright

© 2024 The Author(s). Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.

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Auteurs

Jack R Dunsford (JR)

Department of Kinesiology and Applied Health, University of Winnipeg, Winnipeg, Manitoba, Canada.

Jasvir K Dhaliwal (JK)

Department of Kinesiology and Applied Health, University of Winnipeg, Winnipeg, Manitoba, Canada.

Gracie O Grift (GO)

Department of Kinesiology and Applied Health, University of Winnipeg, Winnipeg, Manitoba, Canada.

Robert Pryce (R)

Department of Kinesiology and Applied Health, University of Winnipeg, Winnipeg, Manitoba, Canada.

Paolo B Dominelli (PB)

Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.

Yannick Molgat-Seon (Y)

Department of Kinesiology and Applied Health, University of Winnipeg, Winnipeg, Manitoba, Canada.
Centre for Heart and Lung Innovation, St. Paul's Hospital, Vancouver, British Columbia, Canada.

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