Temporal trends and treatment patterns in anal fissure management: insights from a multicenter study in Italy.


Journal

Techniques in coloproctology
ISSN: 1128-045X
Titre abrégé: Tech Coloproctol
Pays: Italy
ID NLM: 9613614

Informations de publication

Date de publication:
04 Oct 2024
Historique:
received: 08 05 2024
accepted: 30 08 2024
medline: 4 10 2024
pubmed: 4 10 2024
entrez: 4 10 2024
Statut: epublish

Résumé

Anal fissure (AF) poses a common challenge in clinical practice, prompting various treatment approaches. This multicenter study, conducted by the Italian Society of Colorectal Surgery, aimed to assess treatment trends in AF over a 10 year period. A survey of proctologists and retrospective analysis of patient records were conducted to evaluate treatment modalities and outcomes across six different clinical scenarios based on AF presentation (acute/chronic) stratified by sphincter function (normal/hypertonic/hypotonic). Analysis of data from 17 principal investigators and 22,016 patients revealed significant variability in treatment approaches, influenced by factors such as symptom duration, anal tone, and surgeon preference. Conservative treatments were commonly utilized, while surgical interventions were reserved for refractory cases. Specifically, pharmaceutical treatment was administered to 66-75% of patients in cases of acute AF and 63-67% for chronic AF, while 10-15% underwent anal dilation, and < 2% received botulinum toxin injection. Among medical treatments, nifedipine with lidocaine and glycerin film-forming ointments were the most utilized. The most performed surgical techniques were fissurectomy and anoplasty, except for patients with chronic AF and hypertonic sphincter where sphincterotomy prevailed. Trends in treatment utilization varied depending on the clinical scenario, with notable shifts observed over time. This study provides insights into the evolving landscape of AF management, highlighting the need for further research to elucidate optimal treatment strategies and improve patient outcomes.

Identifiants

pubmed: 39365369
doi: 10.1007/s10151-024-03011-4
pii: 10.1007/s10151-024-03011-4
doi:

Substances chimiques

Lidocaine 98PI200987
Nifedipine I9ZF7L6G2L
Nitroglycerin G59M7S0WS3

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

139

Investigateurs

Ambrosini Fabio (A)
Annicchiarico Alfredo (A)
Antonacci Nicola (A)
Ascari Francesca (A)
Ascenzi Pasquale (A)
Balla Andrea (B)
Barugola Giuliano (B)
Basso Luigi (B)
Beati Claudio (B)
Bellato Vittoria (B)
Benatti Emanuela (B)
Bertoli Paolo (B)
Bottini Corrado (B)
Bracchitta Salvatore (B)
Cafaro Danilo (C)
Calussi Marco (C)
Caminati Filippo (C)
Candilio Giuseppe (C)
Cantarella Salvatore (C)
Carbone Fabio (C)
Carini Stefano (C)
Carrino Francesco (C)
Cestaro Giovanni (C)
Chessa Antonella (C)
Ciferri Enrico (C)
Clementi Marco (C)
Coco Claudio (C)
Cocorullo Gianfranco (C)
Colombo Francesco (C)
Comba Andrea (C)
Conti Luigi (C)
Cracco Nicola (C)
Cravero Francesca (C)
Crea Nicola (C)
Crescenti Fabio (C)
Cuccomarino Salvatore (C)
D'Acapito Fabrizio (D)
D'Onghia Giuliano (D)
De Rosa Michele (R)
Di Pietrantonio Daniela (DP)
Dodi Giuseppe (D)
Ferrario Luca (F)
Fontana Tommaso (F)
Foti Nicola (F)
Geremia Carmelo (G)
Giannini Ivana (G)
Giordano Pasquale (G)
Giuliani Antonio (G)
Guaitoli Eleonora (G)
Laforgia Rita (L)
Lantone Giuliano (L)
Lemma Maria (L)
Lisi Giorgio (L)
Lobascio Pierluigi (L)
Lovisetto Federico (L)
Lucci Enrico (L)
Madeddu Francesco (M)
Magnani Costantino (M)
Mascali Davide (M)
Merlini David (M)
Milito Giovanni (M)
Miro Antonio (M)
Moggia Elisabetta (M)
Monaci Iacopo (M)
Mozzon Marta (M)
Navarra Luca (N)
Oggianu Angelo (O)
Orlandi Simone (O)
Palumbo Alessio (P)
Passaro Umberto (P)
Pata Francesco (P)
Pecorella Giuseppe (P)
Pedrazzani Corrado (P)
Piccolo Davide (P)
Poli Giulia (P)
Rinaldi Marcella (R)
Ripetti Valter (R)
Rizzo Salvatore (R)
Rocco Giuseppe (R)
Sacco Michele (S)
Saroglia Giuliano (S)
Scotto Bruno (S)
Selvaggi Lucio (S)
Silvestri Vania (S)
Soldini Gabriele (S)
Tamini Nicolò (T)
Tanda Cinzia (T)
Terrosu Giovanni (T)
Testa Alessandro (T)
Tomasicchio Giovanni (T)
Turati Luca (T)
Ursino Natale (U)
Vannelli Alberto (V)
Viola Gabriele (V)
Violante Tommaso (V)
Zigiotto Daniele (Z)

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

A Picciariello (A)

Department of Experimental Medicine, University of Salento, Lecce, Italy.

R Tutino (R)

Department of General and Emergency Surgery, AOU Città della Salute e della Scienza, Turin, Italy.

G Gallo (G)

Department of Surgery, Sapienza University of Rome, Rome, Italy. ga.gallo@uniroma1.it.

D F Altomare (DF)

Department of Precision and Regenerative Medicine and Ionian Area and Interdepartmental Research Center for Pelvic Floor Diseases (CIRPAP), University Aldo Moro of Bari, Bari, Italy.

R Pietroletti (R)

Department of Biotechnological and Applied Clinical Sciences, Proctology Unit, University of L'Aquila, L'Aquila, Italy.

A Dezi (A)

Department of Precision and Regenerative Medicine and Ionian Area and Interdepartmental Research Center for Pelvic Floor Diseases (CIRPAP), University Aldo Moro of Bari, Bari, Italy.

G Graziano (G)

Center for Outcomes Research and Clinical Epidemiology (CORESEARCH), Pescara, Italy.

U Grossi (U)

Oncology and Gastroenterology - DiSCOG, University of Padova, Padua, Italy.

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