BCL-X

bcl-X Protein / antagonists & inhibitors Animals Humans Immunoconjugates / pharmacology Xenograft Model Antitumor Assays Mice Cell Line, Tumor Antineoplastic Agents / pharmacology Small Molecule Libraries / pharmacology

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
04 Oct 2024
Historique:
medline: 4 10 2024
pubmed: 4 10 2024
entrez: 4 10 2024
Statut: ppublish

Résumé

Overexpression of the antiapoptotic protein B-cell lymphoma-extra large (BCL-X

Identifiants

DOI: 10.1126/sciadv.ado7120 PMID: 39365864
pubmed: 39365864
doi: 10.1126/sciadv.ado7120
doi:

Substances chimiques

bcl-X Protein 0
Immunoconjugates 0
Antineoplastic Agents 0
BCL2L1 protein, human 0
Small Molecule Libraries 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eado7120

Auteurs

Andrew S Judd (AS)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0003-2562-8841

Bhupinder Bawa (B)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0001-9891-4078

Wayne R Buck (WR)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0002-0698-2178

Zhi-Fu Tao (ZF)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0001-5040-2444

Yingchun Li (Y)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0002-9428-7780

Michael J Mitten (MJ)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Milan Bruncko (M)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Nathaniel Catron (N)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

George Doherty (G)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0006-2283-7962

Kenneth R Durbin (KR)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0001-7163-4877

Brian Enright (B)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Robin Frey (R)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0007-6116-7436

Deanna Haasch (D)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0004-6805-0730

Sandra Haman (S)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0001-7556-9045

Anthony R Haight (AR)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0005-5300-7163

Tracy A Henriques (TA)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

James Holms (J)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0002-7007-3822

Kamel Izeradjene (K)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Russell A Judge (RA)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0001-5917-9269

Gary J Jenkins (GJ)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0004-4585-8542

Aaron Kunzer (A)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Joel D Leverson (JD)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Ruth L Martin (RL)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0002-0318-5325

Diya Mitra (D)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0003-4478-6594

Scott Mittelstadt (S)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0005-7554-2618

Lorne Nelson (L)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0004-8825-209X

Paul Nimmer (P)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0003-4804-4555

Joann Palma (J)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0008-9500-5002

Richard Peterson (R)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0001-3750-817X

Darren C Phillips (DC)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Sherry L Ralston (SL)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0005-4664-4025

Saul H Rosenberg (SH)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Xiaoqiang Shen (X)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0002-2746-4484

Xiaohong Song (X)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Kedar R Vaidya (KR)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0001-6600-2648

Xilu Wang (X)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Jin Wang (J)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0001-5420-5704

Yu Xiao (Y)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Haichao Zhang (H)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

Xinxin Zhang (X)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0009-4032-0272

Eric A Blomme (EA)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0001-5657-7667

Erwin R Boghaert (ER)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.

John C Kalvass (JC)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0000-0003-4414-2804

Andrew Phillips (A)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0008-0826-236X

Andrew J Souers (AJ)

AbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
ORCID: 0009-0002-5965-0633

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines régulatrices de l'apoptose › Protéine bcl-X › BCL-X
questionsmedicales.fr › Eucaryotes › Animaux › BCL-X
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › BCL-X
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Facteurs immunologiques › Immunoconjugués › BCL-X
questionsmedicales.fr › Techniques d'investigation › Transplantation tumorale › Tests d'activité antitumorale sur modèle de xénogreffe › BCL-X
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › BCL-X
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › BCL-X
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › BCL-X
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Bibliothèques de petites molécules › BCL-X