Early developmental alterations of CA1 pyramidal cells in Dravet syndrome.

Dravet syndrome Electrophysiology Excitatory neurons Homeostatic plasticity Neurodevelopment Scn1a expression

Journal

Neurobiology of disease
ISSN: 1095-953X
Titre abrégé: Neurobiol Dis
Pays: United States
ID NLM: 9500169

Informations de publication

Date de publication:
03 Oct 2024
Historique:
received: 19 04 2024
revised: 21 08 2024
accepted: 29 09 2024
medline: 6 10 2024
pubmed: 6 10 2024
entrez: 5 10 2024
Statut: aheadofprint

Résumé

Dravet Syndrome (DS) is most often caused by heterozygous loss-of-function mutations in the voltage-gated sodium channel gene SCN1A (Na

Identifiants

DOI: 10.1016/j.nbd.2024.106688 PMID: 39368670
pubmed: 39368670
pii: S0969-9961(24)00288-2
doi: 10.1016/j.nbd.2024.106688
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106688

Informations de copyright

Copyright © 2024. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest No conflicts to declare.

Auteurs

Steffan P Jones (SP)

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, London, UK.

Nathanael O'Neill (N)

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, London, UK.

Jenna C Carpenter (JC)

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, London, UK.

Sharon Muggeo (S)

San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy.

Gaia Colasante (G)

San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy.

Dimitri M Kullmann (DM)

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, London, UK.

Gabriele Lignani (G)

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, University College London, London, UK. Electronic address: g.lignani@ucl.ac.uk.

Classifications MeSH