The QIBA Profile for Diffusion-Weighted MRI: Apparent Diffusion Coefficient as a Quantitative Imaging Biomarker.


Journal

Radiology
ISSN: 1527-1315
Titre abrégé: Radiology
Pays: United States
ID NLM: 0401260

Informations de publication

Date de publication:
Oct 2024
Historique:
medline: 8 10 2024
pubmed: 8 10 2024
entrez: 8 10 2024
Statut: ppublish

Résumé

The apparent diffusion coefficient (ADC) provides a quantitative measure of water mobility that can be used to probe alterations in tissue microstructure due to disease or treatment. Establishment of the accepted level of variance in ADC measurements for each clinical application is critical for its successful implementation. The Diffusion-Weighted Imaging Biomarker Committee of the Quantitative Imaging Biomarkers Alliance (QIBA) has recently advanced the ADC Profile from the consensus to clinically feasible stage for the brain, liver, prostate, and breast. This profile distills multiple studies on ADC repeatability and describes detailed procedures to achieve stated performance claims on an observed ADC change within acceptable confidence limits. In addition to reviewing the current ADC Profile claims, this report has used recent literature to develop proposed updates for establishing metrology benchmarks for mean lesion ADC change that account for measurement variance. Specifically, changes in mean ADC exceeding 8% for brain lesions, 27% for liver lesions, 27% for prostate lesions, and 15% for breast lesions are claimed to represent true changes with 95% confidence. This report also discusses the development of the ADC Profile, highlighting its various stages, and describes the workflow essential to achieving a standardized implementation of advanced quantitative diffusion-weighted MRI in the clinic. The presented QIBA ADC Profile guidelines should enable successful clinical application of ADC as a quantitative imaging biomarker and ensure reproducible ADC measurements that can be used to confidently evaluate longitudinal changes and treatment response for individual patients.

Identifiants

pubmed: 39377680
doi: 10.1148/radiol.233055
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e233055

Informations de copyright

© RSNA, 2024 See also the editorial by Haider in this issue.

Auteurs

Michael A Boss (MA)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Dariya Malyarenko (D)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Savannah Partridge (S)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Nancy Obuchowski (N)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Amita Shukla-Dave (A)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Jessica M Winfield (JM)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Clifton D Fuller (CD)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Kevin Miller (K)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Virendra Mishra (V)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Michael Ohliger (M)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Lisa J Wilmes (LJ)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Raj Attariwala (R)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Trevor Andrews (T)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Nandita M deSouza (NM)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Daniel J Margolis (DJ)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

Thomas L Chenevert (TL)

From the Center for Research and Innovation, American College of Radiology, 50 S 16th St, Philadelphia, PA 19102 (M.A.B.); Department of Radiology, University of Michigan, Ann Arbor, Mich (D.M., T.L.C.); Department of Radiology, University of Washington, Seattle, Wash (S.P.); Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio (N.O.); Departments of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, New York, NY (A.S.D.); The Institute of Cancer Research, London, UK (J.M.W., N.M.d.S.); The Royal Marsden NHS Foundation Trust, London, UK (J.M.W., N.M.d.S.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Tex (C.D.F.); CaliberMRI, Boulder, Colo (K.M.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (V.M.); Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, Calif (M.O., L.J.W.); Aim Medical Imaging, Vancouver, Canada (R.A.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (T.A.); and Department of Radiology, Weill Cornell Medical College, New York, NY (D.J.M.).

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