Report of a giant invasive, wall-penetrating cardiac lipoma.


Journal

Journal of cardiothoracic surgery
ISSN: 1749-8090
Titre abrégé: J Cardiothorac Surg
Pays: England
ID NLM: 101265113

Informations de publication

Date de publication:
09 Oct 2024
Historique:
received: 26 05 2024
accepted: 30 08 2024
medline: 10 10 2024
pubmed: 10 10 2024
entrez: 9 10 2024
Statut: epublish

Résumé

Cardiac lipoma, a seldom-encountered benign tumor positioned beneath the endocardium, has the potential to impair electrophysiological functions. Diagnosis is principally based on imaging modalities. The uniqueness of this case lies in the tumor's extension both internally and externally within the right atrium, rendering it of special interest. From a clinical standpoint, surgical removal is commonly advocated, wherein early intervention is pivotal in improving patients' long-term prognoses. A 35-year-old male was admitted to the hospital for treatment subsequent to the identification of a cardiac mass two days prior. Initial diagnostic assessments, encompassing CT scans and echocardiography, identified a space-occupying lesion within the heart. The patient underwent surgical excision of the cardiac tumor, utilizing mild hypothermic extracorporeal circulation via femoral vessel access. Intraoperative findings revealed adipose-like tissue of a "dumbbell-shaped" configuration situated both within and external to the right atrium, measuring approximately 8 cm*9 cm internally and 7 cm*6 cm externally, with the extracardiac mass being marginally larger. Postoperative pathological analysis confirmed a cardiac lipoma diagnosis. A follow-up echocardiogram conducted three months post-surgery exhibited no notable abnormalities. The patient is under continuous observation to monitor for any recurrence or potential long-term complications. In this case report, we detail with precision a rare cardiac pathology manifested by an expansive infiltrative lipoma that pervades the endocardial and epicardial layers of the right atrium. After thorough preoperative diagnostic workup and evaluation, we contend that surgical intervention represents the optimal therapeutic approach for managing such conditions, with the goal of preemptively reducing the likelihood of cardiac compression or intracardiac obstruction.

Sections du résumé

BACKGROUND BACKGROUND
Cardiac lipoma, a seldom-encountered benign tumor positioned beneath the endocardium, has the potential to impair electrophysiological functions. Diagnosis is principally based on imaging modalities. The uniqueness of this case lies in the tumor's extension both internally and externally within the right atrium, rendering it of special interest. From a clinical standpoint, surgical removal is commonly advocated, wherein early intervention is pivotal in improving patients' long-term prognoses.
CASE PRESENTATION METHODS
A 35-year-old male was admitted to the hospital for treatment subsequent to the identification of a cardiac mass two days prior. Initial diagnostic assessments, encompassing CT scans and echocardiography, identified a space-occupying lesion within the heart. The patient underwent surgical excision of the cardiac tumor, utilizing mild hypothermic extracorporeal circulation via femoral vessel access. Intraoperative findings revealed adipose-like tissue of a "dumbbell-shaped" configuration situated both within and external to the right atrium, measuring approximately 8 cm*9 cm internally and 7 cm*6 cm externally, with the extracardiac mass being marginally larger. Postoperative pathological analysis confirmed a cardiac lipoma diagnosis. A follow-up echocardiogram conducted three months post-surgery exhibited no notable abnormalities. The patient is under continuous observation to monitor for any recurrence or potential long-term complications.
CONCLUSION CONCLUSIONS
In this case report, we detail with precision a rare cardiac pathology manifested by an expansive infiltrative lipoma that pervades the endocardial and epicardial layers of the right atrium. After thorough preoperative diagnostic workup and evaluation, we contend that surgical intervention represents the optimal therapeutic approach for managing such conditions, with the goal of preemptively reducing the likelihood of cardiac compression or intracardiac obstruction.

Identifiants

pubmed: 39385190
doi: 10.1186/s13019-024-03035-9
pii: 10.1186/s13019-024-03035-9
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

600

Informations de copyright

© 2024. The Author(s).

Références

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doi: 10.1161/CIRCIMAGING.119.009361 pubmed: 31352792
Shu S, Wang J, Zheng C. From pathogenesis to treatment, a systemic review of cardiac lipoma. J Cardiothorac Surg. 2021;16(1):1.
doi: 10.1186/s13019-020-01379-6 pubmed: 33407682 pmcid: 7788760
Li L, Meng J, Zhou X, et al. Surgical treatment of cardiac lipoma: 20 years’ experience in a single center. Chin Med J (Engl). 2023;136(5):565–70.
pubmed: 36848177
Zhu SB, Zhu J, Liu Y, et al. Surgical treatment of a giant symptomatic cardiac lipoma. J Thorac Oncol. 2013;8(10):1341–2.
doi: 10.1097/JTO.0b013e3182a12a6a pubmed: 24457246
Schrepfer S, Deuse T, Detter C, et al. Successful resection of a symptomatic right ventricular lipoma. Ann Thorac Surg. 2003;76(4):1305–7.
doi: 10.1016/S0003-4975(03)00523-X pubmed: 14530040
D’Souza J, Shah R, Abbass A, et al. Invasive Cardiac Lipoma: a case report and review of literature. BMC Cardiovasc Disord. 2017;17(1):28.
doi: 10.1186/s12872-016-0465-2 pubmed: 28088193 pmcid: 5237479
Archontakis S, Koumallos N, Demosthenous M, et al. Epicardial right ventricular lipoma presenting with sustained ventricular tachycardia. J Card Surg. 2018;33(8):438–9.
doi: 10.1111/jocs.13738 pubmed: 29921023
Kashima T, Halai D, Ye H, et al. Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor. Mod Pathol. 2012;25(10):1384–96.
doi: 10.1038/modpathol.2012.90 pubmed: 22699518
Zhu X, Cheng Z, Wang S, et al. The characteristics of invasive cardiac lipoma: case report and literature review. Front Cardiovasc Med. 2023;10:1195582.
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Auteurs

Jingze Zhu (J)

Department of Cardiovascular Surgery of the First Affiliated Hospital, Soochow University, Suzhou, Jiangsu, 215123, China.

Xiangyu Cao (X)

Institute for Cardiovascular Science, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215123, China.

Lei Chen (L)

Department of Cardiovascular Surgery of the First Affiliated Hospital, Soochow University, Suzhou, Jiangsu, 215123, China.

Junjie Song (J)

Department of Cardiovascular Surgery of the First Affiliated Hospital, Soochow University, Suzhou, Jiangsu, 215123, China.

Zhenya Shen (Z)

Department of Cardiovascular Surgery of the First Affiliated Hospital, Soochow University, Suzhou, Jiangsu, 215123, China. uuzyshen@aliyun.com.
Institute for Cardiovascular Science, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215123, China. uuzyshen@aliyun.com.

Yunsheng Yu (Y)

Department of Cardiovascular Surgery of the First Affiliated Hospital, Soochow University, Suzhou, Jiangsu, 215123, China. yys700827@sina.com.
Institute for Cardiovascular Science, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215123, China. yys700827@sina.com.

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