Design and Synthesis of Pyridyl and 2-Hydroxyphenyl Chalcones with Antitubercular Activity.

Chalcones / chemistry Humans Antitubercular Agents / pharmacology Mycobacterium tuberculosis / drug effects Molecular Docking Simulation Drug Design Cell Line, Tumor Structure-Activity Relationship Hep G2 Cells Microbial Sensitivity Tests Cell Proliferation / drug effects Molecular Structure
breast cancer chalcones claisen condensation mycobacterium tuberculosis protein tyrosine phosphatase B (Mbt PtpB)

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
24 Sep 2024
Historique:
received: 30 06 2024
revised: 06 09 2024
accepted: 14 09 2024
medline: 16 10 2024
pubmed: 16 10 2024
entrez: 16 10 2024
Statut: epublish

Résumé

A focussed library of pyridyl and 2-hydroxyphenyl chalcones were synthesized and tested for growth inhibitory activity against

Identifiants

DOI: 10.3390/molecules29194539 PMID: 39407469
pubmed: 39407469
pii: molecules29194539
doi: 10.3390/molecules29194539
pii:
doi:

Substances chimiques

Chalcones 0
Antitubercular Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Kelphina Aziafor (K)

Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.

Ketan Ruparelia (K)

Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.

Brandon Moulds (B)

Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.

Mire Zloh (M)

Faculty of Pharmacy, University Business Academy, 21000 Novi Sad, Serbia.
UCL School of Pharmacy, University College London, 29/39 Brunswick Square, London WC1N 1AX, UK.
ORCID: 0000-0002-4848-2737

Tanya Parish (T)

Center for Global Infectious Disease Research, Seattle Children's Research Institute, 307 Westlake Avenue North, Suite 500, Seattle, WA 98102, USA.

Federico Brucoli (F)

Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
ORCID: 0000-0001-8661-2910

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Chalcones › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Antituberculeux › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Bâtonnets à Gram positif › Bâtonnets asporogènes à Gram positif › Bâtonnets asporogènes réguliers à Gram positif › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Conception de médicament › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Cellules › Cellules épithéliales › Hépatocytes › Cellules HepG2 › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Design and Synthesis of Pyridyl and...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Design and Synthesis of Pyridyl and...