Periostin in Bronchiolitis Obliterans Syndrome after Lung Transplant.

Humans Bronchiolitis Obliterans / etiology Lung Transplantation / adverse effects Cell Adhesion Molecules / blood Male Female Middle Aged Adult Biomarkers / blood Lung / metabolism Forced Expiratory Volume Bronchiolitis Obliterans Syndrome Periostin
bronchiolitis obliterans syndrome chronic lung allograft dysfunction lung function lung transplant periostin

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
27 Sep 2024
Historique:
received: 21 08 2024
revised: 19 09 2024
accepted: 26 09 2024
medline: 16 10 2024
pubmed: 16 10 2024
entrez: 16 10 2024
Statut: epublish

Résumé

The utility of measuring serum periostin levels for predicting the occurrence of bronchiolitis obliterans syndrome (BOS) after lung transplantation remains underexplored. We analyzed differentially expressed genes (DEGs) between initially transplanted lung tissue and lung tissue with BOS from four patients. Periostin levels were assessed in 97 patients who had undergone lung transplantation 1 year post-transplantation and at the onset of BOS. The association between periostin levels and BOS, as well as their correlation with the decline in forced expiratory volume in one second (FEV1), was evaluated. Periostin levels in the BOS group were significantly higher than those in the control group (

Identifiants

DOI: 10.3390/ijms251910423 PMID: 39408746
pubmed: 39408746
pii: ijms251910423
doi: 10.3390/ijms251910423
pii:
doi:

Substances chimiques

POSTN protein, human 0
Cell Adhesion Molecules 0
Biomarkers 0
Periostin 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Pusan National University Yangsan Hospital
ID : 20-2019-007

Auteurs

Hye Ju Yeo (HJ)

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Internal Medicine, Transplant Research Center, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.
Department of Internal Medicine, School of Medicine, Pusan National University, Busan 43241, Republic of Korea.
ORCID: 0000-0002-8403-5790

Junho Kang (J)

Department of research, Keimyung University Donsan Medical Center, Daegu 42601, Republic of Korea.

Yun Hak Kim (YH)

Department of Anatomy, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Department of Biomedical Informatics, School of Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
ORCID: 0000-0002-9796-8266

Woo Hyun Cho (WH)

Division of Allergy, Pulmonary and Critical Care Medicine, Department of Internal Medicine, Transplant Research Center, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.
Department of Internal Medicine, School of Medicine, Pusan National University, Busan 43241, Republic of Korea.
ORCID: 0000-0002-8299-8008

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Maladies pulmonaires › Bronchopneumopathies obstructives › Bronchiolite oblitérante › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation d'organe › Transplantation pulmonaire › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Appareil respiratoire › Poumon › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques respiratoires › Ventilation pulmonaire › Volume expiratoire maximal par seconde › Periostin in Bronchiolitis Obliterans Syndrome...
questionsmedicales.fr › Maladies du système immunitaire › Maladie du greffon contre l'hôte › Syndrome de bronchiolite oblitérante › Periostin in Bronchiolitis Obliterans Syndrome...