TRPV4 Channel Modulators as Potential Drug Candidates for Cystic Fibrosis.

Cystic Fibrosis / drug therapy Humans TRPV Cation Channels / metabolism Cystic Fibrosis Transmembrane Conductance Regulator / metabolism Animals
TRPV4 channels cystic fibrosis lungs motile cilia mucociliary clearance

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
30 Sep 2024
Historique:
received: 26 08 2024
revised: 24 09 2024
accepted: 25 09 2024
medline: 16 10 2024
pubmed: 16 10 2024
entrez: 16 10 2024
Statut: epublish

Résumé

Cystic fibrosis (CF) is a genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (

Identifiants

DOI: 10.3390/ijms251910551 PMID: 39408877
pubmed: 39408877
pii: ijms251910551
doi: 10.3390/ijms251910551
pii:
doi:

Substances chimiques

TRPV Cation Channels 0
Cystic Fibrosis Transmembrane Conductance Regulator 126880-72-6
TRPV4 protein, human 0
CFTR protein, human 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : King Fahad medical city
ID : 023-012

Auteurs

Razan Orfali (R)

Research Center, King Fahad Medical City, Riyadh Second Health Cluster, Riyadh 12231, Saudi Arabia.
ORCID: 0000-0002-0584-4013

Ali AlFaiz (A)

Research Center, King Fahad Medical City, Riyadh Second Health Cluster, Riyadh 12231, Saudi Arabia.

Madhawi Alanazi (M)

Research Center, King Fahad Medical City, Riyadh Second Health Cluster, Riyadh 12231, Saudi Arabia.

Rahaf Alabdulsalam (R)

Research Center, King Fahad Medical City, Riyadh Second Health Cluster, Riyadh 12231, Saudi Arabia.

Meaad Alharbi (M)

Research Center, King Fahad Medical City, Riyadh Second Health Cluster, Riyadh 12231, Saudi Arabia.

Yara Alromaih (Y)

Research Center, King Fahad Medical City, Riyadh Second Health Cluster, Riyadh 12231, Saudi Arabia.

Ismail Dallak (I)

King Abdulaziz Medical City, Jeddah 9515, Saudi Arabia.

Marah Alrahal (M)

Research Center, King Fahad Medical City, Riyadh Second Health Cluster, Riyadh 12231, Saudi Arabia.

Abdulaziz Alwatban (A)

College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh 13317, Saudi Arabia.

Reem Saud (R)

General Education Department, Dar Al-Hikmah University, Jeddah 22246, Saudi Arabia.

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Classifications MeSH

questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies néonatales › Mucoviscidose › TRPV4 Channel Modulators as Potential Drug...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › TRPV4 Channel Modulators as Potential Drug...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Canaux cationiques TRPV › TRPV4 Channel Modulators as Potential Drug...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs d'anions › Transporteurs d'anions organiques › Transporteurs d'anions organiques ATP-dépendants › Protéines associées à la multirésistance aux médicaments › Protéine CFTR › TRPV4 Channel Modulators as Potential Drug...
questionsmedicales.fr › Eucaryotes › Animaux › TRPV4 Channel Modulators as Potential Drug...