Epigenome-wide meta-analysis of prenatal vitamin D insufficiency and cord blood DNA methylation.

Humans DNA Methylation Female Pregnancy Fetal Blood / metabolism Vitamin D Deficiency / genetics Epigenome Vitamin D / blood Adult Male Epigenesis, Genetic Prenatal Exposure Delayed Effects / genetics Genome-Wide Association Study
DNA methylation EWAS PACE Vitamin D Vitamin D insufficiency epigenetics pregnancy

Journal

Epigenetics
ISSN: 1559-2308
Titre abrégé: Epigenetics
Pays: United States
ID NLM: 101265293

Informations de publication

Date de publication:
Dec 2024
Historique:
medline: 18 10 2024
pubmed: 18 10 2024
entrez: 17 10 2024
Statut: ppublish

Résumé

Low maternal vitamin D concentrations during pregnancy have been associated with a range of offspring health outcomes. DNA methylation is one mechanism by which the maternal vitamin D status during pregnancy could impact offspring's health in later life. We aimed to evaluate whether maternal vitamin D insufficiency during pregnancy was conditionally associated with DNA methylation in the offspring cord blood. Maternal vitamin D insufficiency (plasma 25-hydroxy vitamin D

Identifiants

DOI: 10.1080/15592294.2024.2413815 PMID: 39418282
pubmed: 39418282
doi: 10.1080/15592294.2024.2413815
doi:

Substances chimiques

Vitamin D 1406-16-2

Types de publication

Journal Article Meta-Analysis

Langues

eng

Sous-ensembles de citation

IM

Pagination

2413815

Auteurs

Elizabeth W Diemer (EW)

Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Johanna Tuhkanen (J)

Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.

Sara Sammallahti (S)

Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.

Kati Heinonen (K)

Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.
Psychology/Welfare Sciences, Faculty of Social Sciences, Tampere University, Tampere, Finland.

Alexander Neumann (A)

Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.

Sonia L Robinson (SL)

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.

Matthew Suderman (M)

MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Jianping Jin (J)

Westat, Durham, NC, USA.

Christian M Page (CM)

Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Section for Statistics and Data Science, Department of Mathematics, Faculty of Mathematics and Natural Science, University of Oslo, Oslo, Norway.

Ruby Fore (R)

Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.

Sheryl L Rifas-Shiman (SL)

Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.

Emily Oken (E)

Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.

Patrice Perron (P)

Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada.

Luigi Bouchard (L)

Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada.

Marie France Hivert (MF)

Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, QC, Canada.

Katri Räikköne (K)

Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.

Jari Lahti (J)

Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.

Edwina H Yeung (EH)

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.

Weihua Guan (W)

Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA.

Sunni L Mumford (SL)

Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.

Maria C Magnus (MC)

Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.

Siri Håberg (S)

Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.

Wenche Nystad (W)

Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.

Christine L Parr (CL)

Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, Oslo, Norway.

Stephanie J London (SJ)

Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA.

Janine F Felix (JF)

Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Pediatrics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Henning Tiemeier (H)

Department of Child and Adolescent Psychiatry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Phénomènes génétiques › Méthylation de l'ADN › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Structures de l'embryon › Foetus › Sang foetal › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Troubles nutritionnels › Malnutrition › Maladies de carence › Avitaminoses › Carence en vitamine D › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Épigénome › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Composés polycycliques › Composés à cycles fusionnés › Stéroïdes › Sécostéroïdes › Vitamine D › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Maladies urogénitales › Maladies de l'appareil urogénital féminin et complications de la grossesse › Complications de la grossesse › Lésions prénatales › Effets différés de l'exposition prénatale à des facteurs de risque › Epigenome-wide meta-analysis of prenatal...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Épidémiologie moléculaire › Étude d'association pangénomique › Epigenome-wide meta-analysis of prenatal...