Case Report: Copper sulphate related hemophagocytosis with lymphohistiocytosis.
Acute Kidney Injury
Copper Sulphate
Hemophagocytic Lymphohistiocytosis (HLH)
Immune-mediated
Intravascular hemolysis
Journal
F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320
Informations de publication
Date de publication:
2024
2024
Historique:
accepted:
11
04
2024
medline:
21
10
2024
pubmed:
21
10
2024
entrez:
21
10
2024
Statut:
epublish
Résumé
The accidental, suicidal, and homicidal toxicities of copper sulfate have been extensively documented. The later stages of the disease demonstrate signs of systemic toxicity, characterized by intravascular hemolysis, oliguric renal failure, convulsions, and circulatory collapse. Despite the extensive description of life-threatening intravascular hemolysis, Hemophagocytic Lymphohistiocytosis (HLH) related to copper sulfate poisoning has not been described. A 45-year-old male presented with accidental consumption of copper sulfate. Laboratory evaluation revealed leukocytosis, intravascular hemolysis, acute liver injury, acute kidney injury, severe metabolic acidosis, and hyperkalemia. The patient was shifted to the Intensive Care Unit and hemodialysis was initiated. On the 9
Identifiants
pubmed: 39429639
doi: 10.12688/f1000research.147189.1
pmc: PMC11487235
doi:
Substances chimiques
Copper Sulfate
LRX7AJ16DT
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
326Informations de copyright
Copyright: © 2024 Ramachandra K et al.
Déclaration de conflit d'intérêts
No competing interests were disclosed.