NIR-Sensitive Squaraine Dye-Peptide Conjugate for Trypsin Fluorogenic Detection.

Trypsin Fluorescent Dyes / chemistry Peptides / chemistry Cyclobutanes / chemistry Phenols / analysis Humans Biosensing Techniques Spectrometry, Fluorescence
FRET NIR detection aggregation-caused quenching dye–peptide conjugate squaraine dye trypsin detection

Journal

Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191

Informations de publication

Date de publication:
25 Sep 2024
Historique:
received: 01 08 2024
revised: 22 09 2024
accepted: 23 09 2024
medline: 25 10 2024
pubmed: 25 10 2024
entrez: 25 10 2024
Statut: epublish

Résumé

Trypsin enzyme has gained recognition as a potential biomarker in several tumors, such as colorectal, gastric, and pancreatic cancer, highlighting its importance in disease diagnosis. In response to the demand for rapid, cost-effective, and real-time detection methods, we present an innovative strategy utilizing the design and synthesis of NIR-sensitive dye-peptide conjugate (

Identifiants

DOI: 10.3390/bios14100458 PMID: 39451672
pubmed: 39451672
pii: bios14100458
doi: 10.3390/bios14100458
pii:
doi:

Substances chimiques

Trypsin EC 3.4.21.4
squaraine 0
Fluorescent Dyes 0
Peptides 0
Cyclobutanes 0
Phenols 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Priyanka Balyan (P)

Graduate School of Life Science and System Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-Ku, Kitakyushu-Shi, Fukuoka 808-0196, Japan.

Shekhar Gupta (S)

Graduate School of Life Science and System Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-Ku, Kitakyushu-Shi, Fukuoka 808-0196, Japan.

Sai Kiran Mavileti (SK)

Graduate School of Life Science and System Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-Ku, Kitakyushu-Shi, Fukuoka 808-0196, Japan.
ORCID: 0009-0001-4164-158X

Shyam S Pandey (SS)

Graduate School of Life Science and System Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-Ku, Kitakyushu-Shi, Fukuoka 808-0196, Japan.
ORCID: 0000-0001-8102-1003

Tamaki Kato (T)

Graduate School of Life Science and System Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-Ku, Kitakyushu-Shi, Fukuoka 808-0196, Japan.
ORCID: 0000-0001-9080-8916

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › Protéases à sérine › Serine endopeptidases › Trypsine › NIR-Sensitive Squaraine Dye-Peptide Conjugate...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › NIR-Sensitive Squaraine Dye-Peptide Conjugate...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › NIR-Sensitive Squaraine Dye-Peptide Conjugate...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures alicycliques › Cyclobutanes › NIR-Sensitive Squaraine Dye-Peptide Conjugate...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › NIR-Sensitive Squaraine Dye-Peptide Conjugate...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › NIR-Sensitive Squaraine Dye-Peptide Conjugate...
questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Techniques de biocapteur › NIR-Sensitive Squaraine Dye-Peptide Conjugate...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectrométrie de fluorescence › NIR-Sensitive Squaraine Dye-Peptide Conjugate...