Thyrotoxic Periodic Paralysis: A Rare Cause of Quadriparesis in a Young and Seemingly Healthy Patient.


Journal

Medicina (Kaunas, Lithuania)
ISSN: 1648-9144
Titre abrégé: Medicina (Kaunas)
Pays: Switzerland
ID NLM: 9425208

Informations de publication

Date de publication:
14 Oct 2024
Historique:
received: 30 08 2024
revised: 10 10 2024
accepted: 11 10 2024
medline: 26 10 2024
pubmed: 26 10 2024
entrez: 26 10 2024
Statut: epublish

Résumé

Hypokalemia is a common laboratory finding in hospitalized patients, typically resulting from insufficient potassium intake, renal or gastrointestinal losses, or intracellular shifts. While the underlying cause is often easily identifiable, certain cases present diagnostic challenges, and if left unrecognized, the consequences can be life-threatening. We report a rare and atypical case of severe symptomatic hypokalemia as the initial presentation of newly diagnosed Graves' disease. The condition was caused by thyrotoxic periodic paralysis, a rare but serious complication of thyrotoxicosis, predominantly seen in East Asian populations. This disorder is characterized by episodes of acute, reversible muscle weakness associated with transient hypokalemia, which increases the risk of falls and traumatic injuries. The prompt identification of the etiology in such cases is critical for preventing recurrence and avoiding potentially fatal complications.

Identifiants

pubmed: 39459472
pii: medicina60101685
doi: 10.3390/medicina60101685
pii:
doi:

Substances chimiques

Antithyroid Agents 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Adrian-Gabriel Florescu (AG)

Department of Internal Medicine, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania.

Evelina-Ioana Galeș (EI)

Department of Internal Medicine, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania.

Sabina Adriana Frunză (SA)

Department of Internal Medicine, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania.

Camelia Cristina Diaconu (CC)

Department of Internal Medicine, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania.
Faculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, Romania.
Academy of Romanian Scientists, 050045 Bucharest, Romania.

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Classifications MeSH