Isolation and Antibiofilm Activity of Bacteriophages against


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
10 Oct 2024
Historique:
received: 03 09 2024
revised: 24 09 2024
accepted: 07 10 2024
medline: 26 10 2024
pubmed: 26 10 2024
entrez: 26 10 2024
Statut: epublish

Résumé

Infections following shoulder surgery, particularly periprosthetic joint infection (PJI), are challenging to treat. Nine phages with lytic activity were isolated from the skin of humans using The isolated phages displayed lytic activity against a range of Our preclinical findings support the potential of phage therapy as a viable adjunct to traditional antibiotics for treating

Sections du résumé

BACKGROUND BACKGROUND
Infections following shoulder surgery, particularly periprosthetic joint infection (PJI), are challenging to treat.
METHODS METHODS
Nine phages with lytic activity were isolated from the skin of humans using
RESULTS RESULTS
The isolated phages displayed lytic activity against a range of
CONCLUSIONS CONCLUSIONS
Our preclinical findings support the potential of phage therapy as a viable adjunct to traditional antibiotics for treating

Identifiants

pubmed: 39459925
pii: v16101592
doi: 10.3390/v16101592
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Baixing Chen (B)

Department of Trauma Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.
Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.
AO Research Institute Davos, 7270 Davos, Switzerland.

Marco Chittò (M)

AO Research Institute Davos, 7270 Davos, Switzerland.

Siyuan Tao (S)

Laboratory for Biointerfaces, Empa, 9014 St. Gallen, Switzerland.

Jeroen Wagemans (J)

Laboratory of Gene Technology, KU Leuven, 3000 Leuven, Belgium.

Rob Lavigne (R)

Laboratory of Gene Technology, KU Leuven, 3000 Leuven, Belgium.

R Geoff Richards (RG)

AO Research Institute Davos, 7270 Davos, Switzerland.

Willem-Jan Metsemakers (WJ)

Department of Trauma Surgery, University Hospitals Leuven, 3000 Leuven, Belgium.
Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.

T Fintan Moriarty (TF)

AO Research Institute Davos, 7270 Davos, Switzerland.

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Classifications MeSH