Adaptations in hepatic glucose metabolism after chronic social defeat stress in mice.

Animals Liver / metabolism Glucose / metabolism Mice Stress, Psychological / metabolism Male Social Defeat Glycogen / metabolism Blood Glucose / metabolism Brain / metabolism Mice, Inbred C57BL Adaptation, Physiological Glucagon / metabolism Lactic Acid / metabolism
Chronic social defeat Glucagon Glucose Liver Mass spectrometry Mice Stress

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
26 Oct 2024
Historique:
received: 09 07 2024
accepted: 14 10 2024
medline: 27 10 2024
pubmed: 27 10 2024
entrez: 27 10 2024
Statut: epublish

Résumé

Chronic stress has been shown to induce hyperglycemia in both peripheral blood and the brain, yet the detailed mechanisms of glucose metabolism under stress remain unclear. Utilizing

Identifiants

DOI: 10.1038/s41598-024-76310-3 PMID: 39462137
pubmed: 39462137
doi: 10.1038/s41598-024-76310-3
pii: 10.1038/s41598-024-76310-3
doi:

Substances chimiques

Glucose IY9XDZ35W2
Glycogen 9005-79-2
Blood Glucose 0
Glucagon 9007-92-5
Lactic Acid 33X04XA5AT

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

25511

Informations de copyright

© 2024. The Author(s).

Références

Yan, L-J. Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress. J. Diabetes Res. 137919. (2014).
Picard, M., Juster, R. P. & McEwen, B. S. Mitochondrial allostatic load puts the ‘gluc’ back in glucocorticoids. Nat. Rev. Endocrinol. 10, 303–310 (2014).
doi: 10.1038/nrendo.2014.22 pubmed: 24663223
Van der Kooij, M. A. The impact of chronic stress on energy metabolism. Mol. Cell. Neurosci. 107, 103525 (2020).
doi: 10.1016/j.mcn.2020.103525 pubmed: 32629109
Kahl, K. G., Deuschle, M., Stubbs, B. & Schweiger, U. Visceral adipose tissue in patients with severe mental illness. Horm. Mol. Biol. Clin. Investig 33 (2018).
Videbech, P. PET measurements of brain glucose metabolism and blood flow in major depressive disorder. A critical review. Acta Psychiatr Scand. 101, 11–20 (2000).
doi: 10.1034/j.1600-0447.2000.101001011.x pubmed: 10674946
Su, L. et al. Cerebral metabolism in major depressive disorder: A voxel-based meta-analysis of positron emission tomography studies. BMC Psychiatry. 14, 321 (2014).
doi: 10.1186/s12888-014-0321-9 pubmed: 25407081 pmcid: 4240898
Van der Kooij, M. A. Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory. Proc. Natl. Acad. Sci. USA. 115, E10187–E10196 (2018).
pubmed: 30301805 pmcid: 6205456
Carneiro-Nascimento, S. et al. Chronic social stress in mice alters energy status including higher glucose need but lower brain utilization. Psychoneuroendocrinology. 119, 104747 (2020).
doi: 10.1016/j.psyneuen.2020.104747 pubmed: 32563937
Kopfschina Feltes, P. et al. Repeated social defeat induces transient glial activation and brain hypometabolism: a positron emission tomography imaging study. J. Cereb. Blood Flow. Metab. 39, 439–453 (2019).
doi: 10.1177/0271678X17747189
Ekberg, K. et al. Contributions by kidney and liver to glucose production in the postabsorptive state and after 60 h of fasting. Diabetes. 48, 292–298 (1999).
doi: 10.2337/diabetes.48.2.292 pubmed: 10334304
Gerich, J. E. Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: Therapeuric implications. Diabet. Med. 27, 136–142 (2010).
doi: 10.1111/j.1464-5491.2009.02894.x pubmed: 20546255 pmcid: 4232006
Moore, M. C., Coate, K. C., Winnick, J. J., An, Z. & Cherrington, A. D. Regulation of hepatic glucose uptake and storage in vivo. Adv. Nutr. 3, 286–294 (2012).
doi: 10.3945/an.112.002089 pubmed: 22585902 pmcid: 3649460
Scoditti, E., Sabatini, S., Carli, F. & Gastaldelli, A. Hepatic glucose metabolism in the steatotic liver. Nat. Rev. Gastrenterol. Hepatol. 21, 319–334 (2024).
doi: 10.1038/s41575-023-00888-8
Van der Kooij, M. A. et al. Chronic social stress disrupts the intracellular redistribution of brain hexokinase 3 induced by shifts in peripheral glucose levels. J. Mol. Med. (Berl). 100, 1441–1453 (2022).
doi: 10.1007/s00109-022-02235-x pubmed: 35943566
Jones, B. J., Tan, T. & Bloom, S. R. Minireview: glucagon in stress and energy homeostasis. Endocrinology. 153, 1049–1054 (2012).
doi: 10.1210/en.2011-1979 pubmed: 22294753 pmcid: 3281544
Sun, R. C. et al. Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing. Nat. Commun. 8, 1646 (2017).
doi: 10.1038/s41467-017-01518-z pubmed: 29158483 pmcid: 5696342
Jene, T. et al. Chronic social stress lessens the metabolic effects induced by a high-fat diet. J. Endocrinol. 249, 19–30 (2021).
doi: 10.1530/JOE-20-0633 pubmed: 33608492
Fluttert, M., Dalm, S. & Oitzl, M. S. A refined method for sequential blood sampling by tail incision in rats. Lab. Anim. 34, 372–378 (2000).
doi: 10.1258/002367700780387714 pubmed: 11072857
Ruiz de Azua et al. Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages. J. Clin. Invest. 127, 4148–4162 (2017).
doi: 10.1172/JCI83626 pubmed: 29035280 pmcid: 5663356
Krishnan, V. et al. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell. 131, 391–494 (2007).
doi: 10.1016/j.cell.2007.09.018 pubmed: 17956738
Golden, S. A., Covington, H. E. 3rd, Berton, O. & Russo, S. J. A standardized protocol for repeated social defeat stress in mice. Nat. Protoc. 6, 1183–1191 (2011).
doi: 10.1038/nprot.2011.361 pubmed: 21799487 pmcid: 3220278
Jene, T. et al. Temporal profiling of an acute stress-induced behavioral phenotype in mice and role of hippocampal DRR1. Psychoneuroendocrinology 91, 149–158 (2018).
Chen, J-L. et al. H NMR-based metabolic profiling of liver in chronic unpredictable mild stress rats with genipin treatment. J. Pharm. Biomed. Anal. 115, 150–158 (2015).
doi: 10.1016/j.jpba.2015.07.002 pubmed: 26204246
Exton, J. H., Miller, T. B., Harper, S. C. & Park, C. R. Carbohydrate metabolism in perfused livers of adrenalectomized and steroid-replaced rats. Am. J. Physiol. 230, 163–170 (1976).
doi: 10.1152/ajplegacy.1976.230.1.163 pubmed: 175663
Stalmans, W. & Laloux, M. Glucocorticoids and hepatic glycogen metabolism. Monogr. Endocrinol. 12, 517–533 (1979).
doi: 10.1007/978-3-642-81265-1_27 pubmed: 114752
Garcia-Alvarez, M., Marik, P. & Bellomo, R. Stress hyperlactataemia: present understanding and controversy. Lancet Diabetes Endocrinol. 2, 339–347 (2014).
doi: 10.1016/S2213-8587(13)70154-2 pubmed: 24703052
Stanley, W. C. et al. Systemic lactate kinetics during graded exercise in man. Am. J. Physiol. 249, 595–602 (1985).
Razzoli, M. et al. Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis. Mol. Metab. 5, 19–33 (2015).
doi: 10.1016/j.molmet.2015.10.005 pubmed: 26844204 pmcid: 4703853
Han, W., Zheng, Y., Wang, L. & An, C. Disordered gut microbiota and changes in short-chain fatty acids and inflammatory processes in stress-vulnerable mice. J. Neuroimmunol. 383, 578172 (2023).
doi: 10.1016/j.jneuroim.2023.578172 pubmed: 37659269
Morito, K. et al. Sub-chronic and mild social defeat stress exposure to C57BL/6J mice increases visceral fat mass and causes accumulation of cholesterol and bile acids in the liver. Biochem. Biophys. Res. Commun. 702, 149631 (2024).
doi: 10.1016/j.bbrc.2024.149631 pubmed: 38335703
Kuti, D. et al. The metabolic stress response: adaptation to acute-, repeated- and chronic challenges in mice. iScience. 25, 104693 (2022).
doi: 10.1016/j.isci.2022.104693 pubmed: 35880047 pmcid: 9307515
Nikolic, A. et al. Chronic stress alters hepatic metabolism and thermodynamic respiratory efficiency affecting epigenetics in C57BL/6 mice. iScience. 27, 109276 (2024).
doi: 10.1016/j.isci.2024.109276 pubmed: 38450153 pmcid: 10915629
Bloom, S. R., Daniel, P. M., Johnston, D. I., Ogawa, O. & Pratt, O. E. Release of glucagon, induced by stress. Q. J. Exp. Physiol. Cogn. Med. Sci. 58, 99–108 (1973).
pubmed: 4631751
Freeman, B. M. Physiological basis of stress. Proc. R Soc. Med. 68, 427–429 (1975).
pubmed: 1236542 pmcid: 1863919
Robles-Flores, M., Allende, G., Piña, E. & García-Sáinz, J. A. Crosstalk between glucagon- and adenosine-mediated signalling systems in rat hepatocytes: Effects on cyclic AMP-phophodiesterase activity. Biochem. J. 312, 763–767 (1995).
doi: 10.1042/bj3120763 pubmed: 8554517 pmcid: 1136179
Zhang, H., Ma, J., Tang, K. & Huang, B. Beyond energy storage: roles of glycogen in metabolism in health and disease. FEBS J. 288, 3772–3783 (2021).
doi: 10.1111/febs.15648 pubmed: 33249748
Bisschop, P. H., Fliers, E. & Kalsbeek, A. Autonomic regulation of hepatic glycose production. Compr. Physiol. 5, 147–165 (2015).
pubmed: 25589267

Auteurs

Fabiënne S Meijboom (FS)

Department for Developmental Origins of Disease (DDOD), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Annika Hasch (A)

Leibniz Institute for Resilience Research (LIR), Mainz, Germany.

Inigo Ruiz de Azua (I)

Leibniz Institute for Resilience Research (LIR), Mainz, Germany.
Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Camila Takeno Cologna (CT)

Laboratory of Applied Mass Spectrometry, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Center for Cancer Biology, Metabolomics Core Leuven, VIB, Leuven, Belgium.

Shauni Loopmans (S)

Laboratory of Applied Mass Spectrometry, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Center for Cancer Biology, Metabolomics Core Leuven, VIB, Leuven, Belgium.

Beat Lutz (B)

Leibniz Institute for Resilience Research (LIR), Mainz, Germany.
Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Marianne B Müller (MB)

Leibniz Institute for Resilience Research (LIR), Mainz, Germany.
Department of Psychiatry and Psychotherapy, Translational Psychiatry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Bart Ghesquière (B)

Laboratory of Applied Mass Spectrometry, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Center for Cancer Biology, Metabolomics Core Leuven, VIB, Leuven, Belgium.

Michael A van der Kooij (MA)

Department for Developmental Origins of Disease (DDOD), Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. m.a.vanderkooij-9@umcutrecht.nl.
Leibniz Institute for Resilience Research (LIR), Mainz, Germany. m.a.vanderkooij-9@umcutrecht.nl.

Articles similaires

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Meal Timing and Anthropometric and Metabolic Outcomes: A Systematic Review and Meta-Analysis.

Hiu Yee Liu, Ashley A Eso, Nathan Cook et al.
1.00
Humans Meals Time Factors Female Adult

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Système digestif › Foie › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Phénomènes psychologiques › Stress psychologique › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Comportement › Comportement social › Défaite sociale › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Glucides › Polyosides › Glucanes › Glycogène › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Glucides › Sucres › Oses › Hexose › Glucose › Glycémie › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Adaptation physiologique › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Glucagon › Adaptations in hepatic glucose metabolism...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Hydroxyacides › Lactates › Acide lactique › Adaptations in hepatic glucose metabolism...