Antimicrobial surface coating in the emergency department as protective technology for infection control (ASEPTIC): a pilot randomized controlled trial.

Emergency Service, Hospital Pilot Projects Humans Infection Control / methods Disinfection / methods Anti-Infective Agents / pharmacology Methicillin-Resistant Staphylococcus aureus / drug effects Equipment Contamination / prevention & control Cross Infection / prevention & control
Antimicrobial coating Disinfection (MeSH term) Emergency Service, Hospital (MeSH term) Infection Control (MeSH term) Strechers (MeSH term) Surface cleaning

Journal

Antimicrobial resistance and infection control
ISSN: 2047-2994
Titre abrégé: Antimicrob Resist Infect Control
Pays: England
ID NLM: 101585411

Informations de publication

Date de publication:
29 Oct 2024
Historique:
received: 01 06 2024
accepted: 06 10 2024
medline: 29 10 2024
pubmed: 29 10 2024
entrez: 29 10 2024
Statut: epublish

Résumé

We examined the effectiveness of an antimicrobial surface coating for continual disinfection of high touch-frequency surfaces in the emergency department (ED). Following a preliminary observation identifying stretcher rails as the surface with highest touch-frequency in the ED, we conducted a pilot randomized controlled trial involving 96 stretcher rails. The stretchers were randomized to receive an antimicrobial surface coating or placebo coating. Routine cleaning of stretchers subsequently continued as per hospital protocol in both arms. Sampling for total aerobic, gram-positive halophilic, gram-negative and methicillin-resistant Staphylococcus aureus bacteria was performed pre- and post-treatment at 24 h, 7 days and 180 days. Individuals who applied the coating and outcome assessors were blinded to the allocated arms. The primary outcome is contamination of antimicrobial versus placebo rails measured as colony forming units per cm Baseline total aerobic bacteria was comparable between placebo and intervention arms (0.84 versus 1.32 CFU/cm This is the first double-blinded, placebo-controlled, randomized trial to evaluate an antimicrobial surface coating on high touch-frequency surfaces in the emergency department. Total aerobic bacteria found on antimicrobial-coated patient transport stretcher rails was significantly lower than placebo rails at 24 h.

Identifiants

DOI: 10.1186/s13756-024-01481-7 PMID: 39468577
pubmed: 39468577
doi: 10.1186/s13756-024-01481-7
pii: 10.1186/s13756-024-01481-7
doi:

Substances chimiques

Anti-Infective Agents 0

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

129

Informations de copyright

© 2024. The Author(s).

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Auteurs

Lenard Cheng (L)

Emergency Medicine Department, National University Hospital, National University Health System, Level 4, National University Centre for Oral Health Singapore (NUCOHS), 9 Lower Kent Ridge Road, Singapore, 119085, Singapore. lenard_cheng@nuhs.edu.sg.
Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Tower Block, 1E Kent Ridge Road Level 8, Singapore, 119228, Singapore. lenard_cheng@nuhs.edu.sg.

Shun Yee Low (SY)

Department of Emergency Medicine, Sengkang General Hospital, 110 Sengkang East Way, Singapore, 544886, Singapore.
Duke-NUS Medical School, 8 College Rd, Singapore, 169857, Singapore.

Yuru Boon (Y)

Emergency Medicine Department, National University Hospital, National University Health System, Level 4, National University Centre for Oral Health Singapore (NUCOHS), 9 Lower Kent Ridge Road, Singapore, 119085, Singapore.
Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Tower Block, 1E Kent Ridge Road Level 8, Singapore, 119228, Singapore.

Carmen Goh (C)

Department of Emergency Medicine, Ng Teng Fong General Hospital, 1 Jurong East Street 21, Singapore, 609606, Singapore.

Abigail Ng (A)

Emergency Medicine Department, National University Hospital, National University Health System, Level 4, National University Centre for Oral Health Singapore (NUCOHS), 9 Lower Kent Ridge Road, Singapore, 119085, Singapore.

Alexander Jet Yue Ng (AJY)

Emergency Medicine Department, National University Hospital, National University Health System, Level 4, National University Centre for Oral Health Singapore (NUCOHS), 9 Lower Kent Ridge Road, Singapore, 119085, Singapore.
Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Tower Block, 1E Kent Ridge Road Level 8, Singapore, 119228, Singapore.

Joshua Teo (J)

Environmental Health Institute, National Environment Agency (NEA), 11 Biopolis Way, Singapore, 138667, Singapore.
Consumer Chemicals Technology Centre, Department for Technology, Innovation and Enterprise, Singapore Polytechnic, Level 4, T11A, 500 Dover Road, Singapore, 139651, Singapore.

Nur Humaira Johari (NH)

Consumer Chemicals Technology Centre, Department for Technology, Innovation and Enterprise, Singapore Polytechnic, Level 4, T11A, 500 Dover Road, Singapore, 139651, Singapore.
Hilleman Laboratories Pte. Ltd., 21 Biopolis Road, Nucleos North Tower, #04-06/12, Singapore, 138567, Singapore.

Yong Hao Pua (YH)

Department of Physiotherapy, Singapore General Hospital, Singapore General Hospital, Outram Rd, Singapore, 169608, Singapore.
Medicine Academic Programme, Duke-NUS Graduate Medical School, Outram Rd, Singapore, 169608, Singapore.

Mui Teng Chua (MT)

Emergency Medicine Department, National University Hospital, National University Health System, Level 4, National University Centre for Oral Health Singapore (NUCOHS), 9 Lower Kent Ridge Road, Singapore, 119085, Singapore.
Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Tower Block, 1E Kent Ridge Road Level 8, Singapore, 119228, Singapore.

Win Sen Kuan (WS)

Emergency Medicine Department, National University Hospital, National University Health System, Level 4, National University Centre for Oral Health Singapore (NUCOHS), 9 Lower Kent Ridge Road, Singapore, 119085, Singapore.
Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Tower Block, 1E Kent Ridge Road Level 8, Singapore, 119228, Singapore.

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Classifications MeSH

questionsmedicales.fr › Administration des services de santé › Organisation et administration › Administration d'établissement de santé › Administration hospitalière › Services hospitaliers › Service hospitalier d'urgences › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Projets pilotes › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Contrôle des maladies transmissibles › Prévention des infections › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Contrôle des maladies transmissibles › Prévention des infections › Stérilisation › Désinfection › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Contamination de matériel › Antimicrobial surface coating in the emergency...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie iatrogène › Infection croisée › Antimicrobial surface coating in the emergency...