A clinical trial of ropivacaine in arthocentesis for TMD.
Humans
Ropivacaine
/ therapeutic use
Temporomandibular Joint Disorders
/ drug therapy
Anesthetics, Local
/ administration & dosage
Lidocaine
/ therapeutic use
Female
Male
Adult
Interleukin-1beta
/ analysis
Hyaluronic Acid
/ therapeutic use
Pain Measurement
Young Adult
Amides
/ therapeutic use
Interleukin-6
/ analysis
Arthrocentesis
/ methods
Middle Aged
Treatment Outcome
Range of Motion, Articular
/ drug effects
Adolescent
Arthrocentesis
Lidocaine
Ropivacaine
Temporomandibular joint disorder
Journal
BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684
Informations de publication
Date de publication:
29 Oct 2024
29 Oct 2024
Historique:
received:
17
03
2024
accepted:
15
07
2024
medline:
30
10
2024
pubmed:
30
10
2024
entrez:
30
10
2024
Statut:
epublish
Résumé
This study aims to compare the efficacy of ropivacaine and lidocaine in the treatment of temporomandibular joint (TMJ) disorders, with the goal of exploring a more effective treatment for TMJ disorders. Patients with Wilkes stage III and IV unilateral TMJ disorders were enrolled in the study. 0.5% ropivacaine was used for local anesthesia in group A, 2% lidocaine was used in group B. Sodium hyaluronate was injected after supra-articular lavage in both groups. The patients' general conditions, pain scores, and maximum opening before and after treatment were collected, the time of onset and maintenance of anesthesia, and the levels of inflammatory factors IL-1β and IL-6 in the joint lavage fluid were detected. Study showed that the onset of anesthesia was faster and longer maintained in group A. The decrease in IL-1β was more pronounced in group A (16.08 ± 3.10) than in group B (18.03 ± 2.84), p < 0.05. At 2 months after treatment, the joint clicking rate was higher in group A (75%) compared to group B (35%), p < 0.05. At 3 months after treatment, the joint clicking rate was higher in group A (76.69%) compared to group B (40%) and the maximum mouth opening was greater in group A (45.00 ± 2.38) compared to group B (41.73 ± 4.18), p < 0.05. There were no statistically significant differences in VAS score and lateral excursion in group A compared with group B at 2 months and 3 months after treatment. Compared with lidocaine, the application of ropivacaine combined with sodium hyaluronate supra-articular lavage for the treatment of temporomandibular joint disorder is more clinically effective. ChiCTR2300075241 (30/08/2023).
Identifiants
pubmed: 39472858
doi: 10.1186/s12903-024-04606-x
pii: 10.1186/s12903-024-04606-x
doi:
Substances chimiques
Ropivacaine
7IO5LYA57N
Anesthetics, Local
0
Lidocaine
98PI200987
Interleukin-1beta
0
Hyaluronic Acid
9004-61-9
Amides
0
Interleukin-6
0
Types de publication
Journal Article
Randomized Controlled Trial
Comparative Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1311Subventions
Organisme : Guangxi Zhuang Autonomous Region Health and Family Planning Commission, China
ID : S2020042
Informations de copyright
© 2024. The Author(s).
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