Association between night blindness history and risk of diabetes in the Chinese population: a multi-center, cross sectional study.


Journal

BMC endocrine disorders
ISSN: 1472-6823
Titre abrégé: BMC Endocr Disord
Pays: England
ID NLM: 101088676

Informations de publication

Date de publication:
29 Oct 2024
Historique:
received: 06 04 2024
accepted: 05 09 2024
medline: 30 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: epublish

Résumé

Night blindness (NB), an important manifestation of VA deficiency, may be associated with the odds of diabetes. The aim of this study was to explore the probable association between NB history and diabetes in Chinese community-dwelling adults. This multi-center, cross-sectional study enrolled a total of 5664 participants aged 18-82 years from eight sites in China. Information on demographics and medical history was collected using a standardized questionnaire. Diabetes was diagnosed based on the oral glucose tolerance test or a self-reported history. NB history was ascertained by a face-to-face interview with reference to the recommendation by the World Health Organization. Logistic regression analysis was used to evaluate the association between NB history and the odds of diabetes. A total of 5049 participants were finally included, with 252 ascertained with NB history and 1076 with diabetes. The mean age of included participants was 52.9 years, and the percentage of participants with NB history was significantly higher in participants with diabetes than those without (7.0% vs. 4.5%). The multivariable adjusted odds ratio for diabetes was 1.41 (95% confidence interval 1.06, 1.89) in participants with NB history compared with those without. Furthermore, mediation analysis showed that obesity, as assessed by waist-height ratio, partially mediated the relationship between NB history and increased odds of diabetes. The results suggest that NB history might be associated with increased odds of diabetes in Chinese community-dwelling adults.

Identifiants

pubmed: 39472978
doi: 10.1186/s12902-024-01721-2
pii: 10.1186/s12902-024-01721-2
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

231

Subventions

Organisme : the Key Research and Development Program in Jiangsu Province
ID : BE2022828
Organisme : the Excellence Project Funds of Southeast University
ID : 1190001801
Organisme : the Open Project Program of the Key Base for Standardized Training for General Physicians from Zhongda Hospital
ID : ZDZYJD-QK-2022-7
Organisme : the National Key R&D Program of China
ID : 2016YFC1305700

Informations de copyright

© 2024. The Author(s).

Références

Valdés-Ramos R, et al. Vitamins and type 2 diabetes mellitus. Endocr Metab Immune Disord Drug Targets. 2015;15(1):54–63.
pubmed: 25388747 pmcid: 4435229 doi: 10.2174/1871530314666141111103217
Carazo A, et al. Vitamin A update: forms, sources, kinetics, detection, function, deficiency, therapeutic use and toxicity. Nutrients. 2021;13(5):1703.
Zhang Y, et al. Vitamin A and diabetes. J Med Food. 2021;24(8):775–85.
pubmed: 33232625 doi: 10.1089/jmf.2020.0147
Blaner WS. Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders. Pharmacol Ther. 2019;197:153–78.
pubmed: 30703416 pmcid: 6520171 doi: 10.1016/j.pharmthera.2019.01.006
Iqbal S, Naseem I. Role of vitamin A in type 2 diabetes mellitus biology: effects of intervention therapy in a deficient state. Nutrition. 2015;31(7–8):901–7.
pubmed: 26001806 doi: 10.1016/j.nut.2014.12.014
Matthews KA, et al. Vitamin A deficiency impairs fetal islet development and causes subsequent glucose intolerance in adult rats. J Nutr. 2004;134(8):1958–63.
pubmed: 15284383 doi: 10.1093/jn/134.8.1958
Trasino SE, Benoit YD, Gudas LJ. Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass. J Biol Chem. 2015;290(3):1456–73.
pubmed: 25451926 doi: 10.1074/jbc.M114.616763
Zhou Y, et al. Vitamin A deficiency causes islet dysfunction by inducing islet stellate cell activation via cellular retinol binding protein 1. Int J Biol Sci. 2020;16(6):947–56.
pubmed: 32140064 pmcid: 7053333 doi: 10.7150/ijbs.37861
Mody N. Alterations in vitamin A/retinoic acid homeostasis in diet-induced obesity and insulin resistance. Proc Nutr Soc. 2017;76(4):597–602.
pubmed: 28651670 doi: 10.1017/S0029665117001069
Chen G. Roles of vitamin A metabolism in the development of hepatic insulin resistance. ISRN Hepatol. 2013;2013:534972.
pubmed: 27335827 pmcid: 4890907 doi: 10.1155/2013/534972
Wei X, et al. Serum vitamin A status is associated with obesity and the metabolic syndrome among school-age children in Chongqing, China. Asia Pac J Clin Nutr. 2016;25(3):563–70.
pubmed: 27440692
Qorbani M, et al. Association of serum retinol concentrations with metabolic Syndrome components in Iranian children and adolescents: the CASPIAN-V Study. Front Nutr. 2022;9:807634.
pubmed: 35634391 pmcid: 9137422 doi: 10.3389/fnut.2022.807634
Harris EW, Loewenstein JI, Azar D. Vitamin A deficiency and its effects on the eye. Int Ophthalmol Clin. 1998;38(1):155–61.
pubmed: 9532479 doi: 10.1097/00004397-199803810-00013
Smith J, Steinemann TL. Vitamin A deficiency and the eye. Int Ophthalmol Clin. 2000;40(4):83–91.
pubmed: 11064859 doi: 10.1097/00004397-200010000-00007
Chakraborty U, Chandra A. Bitot’s spots, dry eyes, and night blindness indicate vitamin A deficiency. Lancet. 2021;397(10270):e2.
pubmed: 33453784 doi: 10.1016/S0140-6736(21)00041-6
Wirth JP, et al. Vitamin A supplementation programs and country-level evidence of vitamin A deficiency. Nutrients. 2017;9(3):190.
Tavridou A, et al. Serum concentrations of vitamins a and E in impaired glucose tolerance. Clin Chim Acta. 1997;266(2):129–40.
pubmed: 9437541 doi: 10.1016/S0009-8981(97)00123-X
Kim M, et al. Serum vitamin A-related metabolite levels are associated with incidence of type 2 diabetes. Diabetes Metab. 2017;43(3):287–91.
pubmed: 27840113 doi: 10.1016/j.diabet.2016.09.012
Broch M, et al. Circulating retinol-binding protein-4, insulin sensitivity, insulin secretion, and insulin disposition index in obese and nonobese subjects. Diabetes Care. 2007;30(7):1802–6.
pubmed: 17416795 doi: 10.2337/dc06-2034
Bojanic D, et al. Waist circumference, waist-to-hip ratio, and waist-to-height ratio reference percentiles for abdominal obesity among Macedonian adolescents. Nutr Hosp. 2020;37(4):786–93.
pubmed: 32686451
Parente EB, et al. Waist-height ratio and waist are the best estimators of visceral fat in type 1 diabetes. Sci Rep. 2020;10(1):18575.
pubmed: 33122731 pmcid: 7596092 doi: 10.1038/s41598-020-75667-5
Wu HY, Xu SY, Chen LL, Zhang HF. Waist to height ratio as a predictor of abdominal fat distribution in men. Chin J Physiol. 2009;52(6):441–5.
pubmed: 20337152 doi: 10.4077/CJP.2009.AMH064
Zhang FL, et al. Strong Association of Waist Circumference (WC), Body Mass Index (BMI), Waist-to-Height Ratio (WHtR), and Waist-to-Hip Ratio (WHR) with Diabetes: A Population-Based Cross-Sectional Study in Jilin Province. China J Diabetes Res. 2021;2021:8812431.
pubmed: 34056007
García OP, Long KZ, Rosado JL. Impact of micronutrient deficiencies on obesity. Nutr Rev. 2009;67(10):559–72.
pubmed: 19785688 doi: 10.1111/j.1753-4887.2009.00228.x
Vaughan LA, Benyshek DC, Martin JF. Food acquisition habits, nutrient intakes, and anthropometric data of Havasupai adults. J Am Diet Assoc. 1997;97(11):1275–82.
pubmed: 9366866 doi: 10.1016/S0002-8223(97)00305-2
de Silva SV, da Veiga L.G Valeria, Ramalho RA. Association of serum concentrations of retinol and carotenoids with overweight in children and adolescents. Nutrition. 2007;23(5):392–7.
doi: 10.1016/j.nut.2007.02.009
Bento C, et al. Vitamin A deficiency is associated with body mass index and body adiposity in women with recommended intake of vitamin A. Nutr Hosp. 2018;35(5):1072–8.
pubmed: 30307289 doi: 10.20960/nh.1630
Jeyakumar SM, et al. Vitamin a supplementation induces adipose tissue loss through apoptosis in lean but not in obese rats of the WNIN/Ob strain. J Mol Endocrinol. 2005;35(2):391–8.
pubmed: 16216918 doi: 10.1677/jme.1.01838
Jeyakumar SM, Vajreswari A, Giridharan NV. Chronic dietary vitamin a supplementation regulates obesity in an obese mutant WNIN/Ob rat model. Obes (Silver Spring). 2006;14(1):52–9.
doi: 10.1038/oby.2006.7
Qiu S, et al. Exploration and validation of the performance of Hemoglobin A1c in detecting diabetes in community-dwellers with hypertension. Ann Lab Med. 2020;40(6):457–65.
Liu Y, et al. Novel clusters of newly-diagnosed type 2 diabetes and their association with diabetic retinopathy: a 3-year follow-up study. Acta Diabetol. 2022;59(6):827–35.
pubmed: 35312861 doi: 10.1007/s00592-022-01872-5
Drouin P, et al. [Diagnosis and classification of diabetes mellitus: the new criteria]. Diabetes Metab. 1999;25(1):72–83.
pubmed: 10335427
Sommer A, et al. History of nightblindness: a simple tool for xerophthalmia screening. Am J Clin Nutr. 1980;33(4):887–91.
pubmed: 6965817 doi: 10.1093/ajcn/33.4.887
Sherwin JC, et al. Epidemiology of vitamin A deficiency and xerophthalmia in at-risk populations. Trans R Soc Trop Med Hyg. 2012;106(4):205–14.
pubmed: 22326691 doi: 10.1016/j.trstmh.2012.01.004
Lin L, et al. [Survey on vitamin A deficiency in children under-6-years in China]. Zhonghua Yu Fang Yi Xue Za Zhi. 2002;36(5):315–9.
pubmed: 12411191
Mi J, et al. [Prevalence of vitamin A deficiency in children under six years of age in Tibet, China]. Zhonghua Yu Fang Yi Xue Za Zhi. 2003;37(6):419–22.
pubmed: 14703496
Song P et al. The prevalence of vitamin A deficiency in Chinese children: a systematic review and bayesian Meta-analysis. Nutrients. 2017;9(12):1285.
Wang R, et al. Serum vitamin a nutritional status of children and adolescents aged 6–17 years - China, 2016–2017. China CDC Wkly. 2021;3(9):189–92.
pubmed: 34595041 pmcid: 8393032 doi: 10.46234/ccdcw2021.057
Mao D, et al. [Vitamin A nutrition status of Chinese urban adults aged 18 to 60 years old in 2015]. Wei Sheng Yan Jiu. 2022;51(3):381–5.
pubmed: 35718898
Shah M, et al. Comparison of nutrient intakes in South asians with type 2 diabetes mellitus and controls living in the United States. Diabetes Res Clin Pract. 2018;138:47–56.
pubmed: 29382587 doi: 10.1016/j.diabres.2018.01.016
Khayyatzadeh SS, et al. Nutrient patterns and their relationship to metabolic syndrome in Iranian adults. Eur J Clin Invest. 2016;46(10):840–52.
pubmed: 27529331 doi: 10.1111/eci.12666
Godala M, et al. The risk of plasma vitamin A, C, E and D deficiency in patients with metabolic syndrome: a case-control study. Adv Clin Exp Med. 2017;26(4):581–6.
pubmed: 28691410 doi: 10.17219/acem/62453
Pereira S, et al. Class III obesity and its relationship with the nutritional status of vitamin A in pre- and postoperative gastric bypass. Obes Surg. 2009;19(6):738–44.
pubmed: 18392900 doi: 10.1007/s11695-008-9478-y
Viroonudomphol D, et al. The relationships between anthropometric measurements, serum vitamin A and E concentrations and lipid profiles in overweight and obese subjects. Asia Pac J Clin Nutr. 2003;12(1):73–9.
pubmed: 12737014
Zhang Y, et al. Vitamin A status affects obesity development and hepatic expression of key genes for fuel metabolism in Zucker fatty rats. Biochem Cell Biol. 2012;90(4):548–57.
pubmed: 22554462 doi: 10.1139/o2012-012
Hong SE, et al. Effect of retinoic acid on leptin, glycerol, and glucose levels in mature rat adipocytes in vitro. J Med Food. 2004;7(3):320–6.
pubmed: 15383226 doi: 10.1089/jmf.2004.7.320
Frey SK, Vogel S. Vitamin a metabolism and adipose tissue biology. Nutrients. 2011;3(1):27–39.
pubmed: 22254074 pmcid: 3257733 doi: 10.3390/nu3010027
Hu FB, et al. Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med. 2001;345(11):790–7.
pubmed: 11556298 doi: 10.1056/NEJMoa010492
Ford ES, Williamson DF, Liu S. Weight change and diabetes incidence: findings from a national cohort of US adults. Am J Epidemiol. 1997;146(3):214–22.
pubmed: 9247005 doi: 10.1093/oxfordjournals.aje.a009256
Maggio CA. F.X. Pi-Sunyer 2003 Obesity and type 2 diabetes. Endocrinol Metab Clin North Am 32 4 805–22 viii.
pubmed: 14711063 doi: 10.1016/S0889-8529(03)00071-9
Góes É et al. Vitamin A deficiency and its association with visceral adiposity in women. Biomedicines. 2023;11(3):991.
McLaren DS, Kraemer K. Interaction of vitamin A and other micronutrients. World Rev Nutr Diet. 2012;103:101–5.
pubmed: 23008041 doi: 10.1159/000171010

Auteurs

Jinbang Wang (J)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.
Northern Jiangsu People's Hospital, Yangzhou, Jiangsu, 225001, P.R. China.

Yunting Zhou (Y)

Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China.

Yu Liu (Y)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Miaomiao Sang (M)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Yuzhi Ding (Y)

Department of Ophthalmology, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China.

Tingting Li (T)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Xiaohang Wang (X)

Institute of Translational Medicine, Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College, Yangzhou University, Yangzhou, 225009, P. R. China.

Vladmir Carvalho (V)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Chengming Ni (C)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Qianqian Wang (Q)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Zhensheng Cai (Z)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Huan Wang (H)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Yang Chen (Y)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Zhanjia Shang (Z)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China.

Duolao Wang (D)

Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.

Shanhu Qiu (S)

Department of General Practice, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China. tigershanhu@126.com.

Zilin Sun (Z)

Department of Endocrinology, Zhongda Hospital, Institute of Diabetes, School of Medicine, Southeast University, Nanjing, China. sunzilin1963@126.com.

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