Complication avoidance, rehabilitation, pain therapy and palliative care for patients with metastatic spine tumors: WFNS spine committee recommendations.


Journal

Neurosurgical review
ISSN: 1437-2320
Titre abrégé: Neurosurg Rev
Pays: Germany
ID NLM: 7908181

Informations de publication

Date de publication:
30 Oct 2024
Historique:
received: 12 07 2024
accepted: 13 10 2024
revised: 09 10 2024
medline: 31 10 2024
pubmed: 30 10 2024
entrez: 30 10 2024
Statut: epublish

Résumé

This review aims to formulate the most current, evidence-based recommendations regarding complication avoidance, rehabilitation, pain therapy and palliative care for patients with metastatic spine tumors. A systematic literature search in PubMed and MEDLINE, and was performed from 2013 to 2023 using the search terms "complications" + "spine metastases", "spine metastases" + + "rehabilitation", "spine metastases" + "pain therapy" + "palliative care". Screening criteria resulted in 35, 15 and 56 studies respectively that were analyzed. Using the Delphi method and two rounds of voting at two separate international meetings, nine members of the WFNS (World Federation of Neurosurgical Societies) Spine Committee generated nine final consensus statements. Preoperative assessment for complications following surgery in patients with metastatic spine tumors should include estimation of Karnofsky score, site of primary tumor, number of spinal and visceral metastasis, ASA score and preoperative Hb (Hemoglobin) value. Complication risk factors are age > 65 years, preoperative ASA score of 3 and 4 and greater operative blood loss. Pain management using WHO analgesic concept and early mobilization are needed, starting with non-opioids, weak opioids followed by strong opioids. Morphine is the first choice for moderate to severe pain whereas IV-PCA may be used for severe breakthrough pain with monitoring. Use of bisphosphonates is considered in cases of non-localized pain and not accessible radiation therapy. These nine final consensus statements provide current, evidence-based guidelines on complication avoidance, rehabilitation, pain therapy and palliative care for patients with spinal metastases.

Identifiants

pubmed: 39476270
doi: 10.1007/s10143-024-03050-3
pii: 10.1007/s10143-024-03050-3
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

830

Informations de copyright

© 2024. The Author(s).

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Auteurs

Mirza Pojskic (M)

Department of Neurosurgery, University of Marburg, Marburg, Germany. mirza.po@gmail.com.

Sait Naderi (S)

Department of Neurosurgery, Istanbul Brain and Spine Center, Istanbul, Türkiye, Turkey.

Sandeep Vaishya (S)

Department of Neurosurgery, Fortis Memorial Research Institute, Guragaon and Fortis Hospital Vasant Kunj, New Delhi, India.
Fortis Memorial Hospital, New Delhi, India.

Mehmet Zileli (M)

Department of Neurosurgery, Sanko University, Gaziantep, Türkiye, Turkey.

Francesco Costa (F)

Spine Surgery Unit, Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.

Salman Sharif (S)

Department of Neurosurgery, Liaquat National Hospital and Medical College, Karachi, Pakistan.

Ziya L Gokaslan (ZL)

Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

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