Risk factors and drug resistance of adult community-onset urinary tract infections caused by


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
29 Oct 2024
Historique:
medline: 31 10 2024
pubmed: 31 10 2024
entrez: 30 10 2024
Statut: epublish

Résumé

To evaluate the prevalence, resistance and risk factors of community-onset urinary tract infections (COUTIs) caused by extended-spectrum β-lactamase-producing A retrospective case-control study. The Affiliated Dazu Hospital of Chongqing Medical University (also known as The People's Hospital of Dazu Chongqing), a 1000-bed tertiary hospital in China. This study encompassed adult patients diagnosed with community-acquired urinary tract infections (UTIs) caused by The risk factors for COUTIs caused by ESBL-EC were evaluated using a case-control design, defining patients who were diagnosed with UTIs and had an ESBL-positive urine culture as the case group and patients who were diagnosed with UTIs and had an ESBL-negative urine culture as the control group. Perform drug susceptibility testing and resistance analysis on isolated ESBL-EC. In total, 394 cases of COUTIs caused by Our results revealed high ESBL-EC detection rates. COUTIs caused by ESBL-EC are more likely to occur in patients with parenchymal tumour, a history of urolithiasis stone fragmentation, a history of urological surgery, hospitalisation within 6 months, indwelling catheter outside the hospital and use of third-generation cephalosporins. These patients were highly resistant to penicillins, cephalosporins and quinolones.

Identifiants

pubmed: 39477264
pii: bmjopen-2024-090665
doi: 10.1136/bmjopen-2024-090665
doi:

Substances chimiques

beta-Lactamases EC 3.5.2.6
Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e090665

Informations de copyright

© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Yan-Ling Zhou (YL)

Department of Infectious Disease, The People's Hospital of Dazu Chongqing, Chongqing, China.

Biao-Li Long (BL)

Department of Otorhinolaryngology, The People's Hospital of Dazu Chongqing, Chongqing, China.

He-Lei Liu (HL)

Department of Infectious Disease, The People's Hospital of Dazu Chongqing, Chongqing, China.

Jing Wu (J)

Department of Infectious Disease, The People's Hospital of Dazu Chongqing, Chongqing, China 2861914532@qq.com.

Hong Xia (H)

Department of Infectious Disease, The People's Hospital of Dazu Chongqing, Chongqing, China.

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Classifications MeSH