Risk factors and drug resistance of adult community-onset urinary tract infections caused by
Humans
Urinary Tract Infections
/ microbiology
Retrospective Studies
China
/ epidemiology
Male
Female
Community-Acquired Infections
/ microbiology
Escherichia coli
/ isolation & purification
Risk Factors
Escherichia coli Infections
/ epidemiology
beta-Lactamases
/ metabolism
Case-Control Studies
Middle Aged
Anti-Bacterial Agents
/ therapeutic use
Adult
Aged
Microbial Sensitivity Tests
Drug Resistance, Bacterial
Prevalence
Adult urology
Case-Control Studies
Community Participation
Public Health
Urinary tract infections
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
29 Oct 2024
29 Oct 2024
Historique:
medline:
31
10
2024
pubmed:
31
10
2024
entrez:
30
10
2024
Statut:
epublish
Résumé
To evaluate the prevalence, resistance and risk factors of community-onset urinary tract infections (COUTIs) caused by extended-spectrum β-lactamase-producing A retrospective case-control study. The Affiliated Dazu Hospital of Chongqing Medical University (also known as The People's Hospital of Dazu Chongqing), a 1000-bed tertiary hospital in China. This study encompassed adult patients diagnosed with community-acquired urinary tract infections (UTIs) caused by The risk factors for COUTIs caused by ESBL-EC were evaluated using a case-control design, defining patients who were diagnosed with UTIs and had an ESBL-positive urine culture as the case group and patients who were diagnosed with UTIs and had an ESBL-negative urine culture as the control group. Perform drug susceptibility testing and resistance analysis on isolated ESBL-EC. In total, 394 cases of COUTIs caused by Our results revealed high ESBL-EC detection rates. COUTIs caused by ESBL-EC are more likely to occur in patients with parenchymal tumour, a history of urolithiasis stone fragmentation, a history of urological surgery, hospitalisation within 6 months, indwelling catheter outside the hospital and use of third-generation cephalosporins. These patients were highly resistant to penicillins, cephalosporins and quinolones.
Identifiants
pubmed: 39477264
pii: bmjopen-2024-090665
doi: 10.1136/bmjopen-2024-090665
doi:
Substances chimiques
beta-Lactamases
EC 3.5.2.6
Anti-Bacterial Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e090665Informations de copyright
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.