Human prolyl hydroxylase domain 2 reacts with O
Humans
Ketoglutaric Acids
/ metabolism
Hypoxia-Inducible Factor-Proline Dioxygenases
/ metabolism
Oxygen
/ metabolism
Hypoxia-Inducible Factor 1, alpha Subunit
/ metabolism
Basic Helix-Loop-Helix Transcription Factors
/ metabolism
Hydroxylation
Crystallography, X-Ray
Oxidation-Reduction
Models, Molecular
Protein Binding
Epigenetics
Hypoxia inducible factor
Hypoxia/oxygen sensing
L-Ascorbic acid/vitamin C
Prolyl hydroxylase domain (PHD)/EGLN enzyme
Transcriptional regulation
α-Ketoglutarate/2-oxoglutarate oxygenase
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
30 10 2024
30 10 2024
Historique:
received:
16
07
2024
accepted:
08
10
2024
medline:
31
10
2024
pubmed:
31
10
2024
entrez:
31
10
2024
Statut:
epublish
Résumé
Hypoxia inducible transcription factors (HIFs) mediate the hypoxic response in metazoans. When sufficient O
Identifiants
pubmed: 39478091
doi: 10.1038/s41598-024-75761-y
pii: 10.1038/s41598-024-75761-y
doi:
Substances chimiques
Ketoglutaric Acids
0
Hypoxia-Inducible Factor-Proline Dioxygenases
EC 1.14.11.29
Oxygen
S88TT14065
EGLN1 protein, human
EC 1.14.11.2
Hypoxia-Inducible Factor 1, alpha Subunit
0
Basic Helix-Loop-Helix Transcription Factors
0
endothelial PAS domain-containing protein 1
1B37H0967P
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
26162Subventions
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/L000121/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/J001694/2
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R013829/1
Pays : United Kingdom
Organisme : Cancer Research UK
ID : C8717/A18245
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 091857/7/10/7
Pays : United Kingdom
Organisme : EPSRC
ID : EP/L011972/1
Informations de copyright
© 2024. The Author(s).
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