Wernicke's encephalopathy with pinpoint pupils and diplopia.


Journal

BMC neurology
ISSN: 1471-2377
Titre abrégé: BMC Neurol
Pays: England
ID NLM: 100968555

Informations de publication

Date de publication:
30 Oct 2024
Historique:
received: 07 09 2024
accepted: 23 10 2024
medline: 31 10 2024
pubmed: 31 10 2024
entrez: 31 10 2024
Statut: epublish

Résumé

This case report presents the clinical findings of a female patient diagnosed with Wernicke's encephalopathy, characterized by pinpoint pupils. While pupillary changes can occur in Wernicke's encephalopathy, the presence of pinpoint pupils is exceedingly rare. In this report, we aim to document and discuss this unusual presentation, as well as speculate on the potential mechanisms underlying this atypical manifestation of the disease.

Identifiants

pubmed: 39478488
doi: 10.1186/s12883-024-03935-2
pii: 10.1186/s12883-024-03935-2
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

422

Subventions

Organisme : Second Hospital of Shandong University
ID : 2022YP55

Informations de copyright

© 2024. The Author(s).

Références

Ota Y, Capizzano AA, Moritani T, Naganawa S, Kurokawa R, Srinivasan A. Comprehensive review of Wernicke encephalopathy: pathophysiology, clinical symptoms and imaging findings. Jpn J Radiol. 2020;38:809–20.
doi: 10.1007/s11604-020-00989-3 pubmed: 32390125
Zuccoli G, Gallucci M, Capellades J, Regnicolo L, Tumiati B, Giadas TC, et al. Wernicke Encephalopathy: MR Findings at Clinical Presentation in twenty-six alcoholic and nonalcoholic patients. Am J Neuroradiol. 2007;28:1328–31.
doi: 10.3174/ajnr.A0544 pubmed: 17698536 pmcid: 7977668
D Caine GMH, J Kril J CGH. Operational criteria for the classification of chronic alcoholics: identification of Wemicke’s encephalopathy. J Neurol Neurosurg Psychiatry. 1997;62:51–60.
doi: 10.1136/jnnp.62.1.51
Kattah JC. The spectrum of vestibular and Ocular Motor Abnormalities in Thiamine Deficiency. Current Neurology and Neuroscience Reports; 2017. p. 17.
Castaigne P, Laplane D, Saraux H, Augustin P. 1970. 2 cases of Gayet-Wernicke encephalopathy with isolated unilateral mydriasis. In Revue neurologique. 368–370.
Liu Y, Rodenkirch C, Moskowitz N, Schriver B, Wang Q. Dynamic lateralization of Pupil Dilation evoked by Locus Coeruleus activation results from sympathetic, not parasympathetic, contributions. Cell Rep. 2017;20:3099–112.
doi: 10.1016/j.celrep.2017.08.094 pubmed: 28954227 pmcid: 5679481
Brasil Neto JP, Henriques EDTFG. Bilateral palpebral ptosis with unilateral paralysis of upward gaze: a case report. Arq Neuropsiquiatr. 1986;44:82–8.
doi: 10.1590/S0004-282X1986000100012 pubmed: 3741187
Yeh SJTL, Tang SC, Jeng JS. Pin-point pupils with drowsiness as a presentation of Hashimoto’s encephalopathy mimicking pontine infarction. Acta Neurol Taiwan. 2014;23:19–23.
pubmed: 24833211
Wilhelm H. 2011. Disorders of the pupil. In Neuro-ophthalmology. 427–466.
Parkinson D. Further observations on the sympathetic pathways to the pupil. Anat Rec. 1988;220:108–9.
doi: 10.1002/ar.1092200113 pubmed: 3348484
Baklavadzhyan OGK, Lebedev RK, Skobelev VP, Sarukhanyan VA, R. V. Study of pathways transmitting sympathetic-activating influences from hypothalamus to spinal cord. NEUROPHYSIOLOGY. 1983;14:230–6.
doi: 10.1007/BF01065128

Auteurs

Hongjia Xu (H)

Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Na Shao (N)

Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Zhengyu Zhu (Z)

Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Pin Wang (P)

Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Lin Sun (L)

Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Yingying Xu (Y)

Department of Neurology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. xuyingying@email.sdu.edu.cn.

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Classifications MeSH