Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition.

aerosol-borne chamber inactivation influenza A virus nebulizers

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2024
Historique:
received: 22 08 2024
accepted: 03 10 2024
medline: 31 10 2024
pubmed: 31 10 2024
entrez: 31 10 2024
Statut: epublish

Résumé

We describe a novel biosafety aerosol chamber equipped with state-of-the-art instrumentation for bubble-bursting aerosol generation, size distribution measurement, and condensation-growth collection to minimize sampling artifacts when measuring virus infectivity in aerosol particles. Using this facility, we investigated the effect of relative humidity (RH) in very clean air without trace gases (except ∼400 ppm CO

Identifiants

DOI: 10.3389/fmicb.2024.1484992 PMID: 39479211 PMC: PMC11521868
pubmed: 39479211
doi: 10.3389/fmicb.2024.1484992
pmc: PMC11521868
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1484992

Informations de copyright

Copyright © 2024 Motos, Schaub, David, Costa, Terrettaz, Kaltsonoudis, Glas, Klein, Bluvshtein, Luo, Violaki, Pohl, Hugentobler, Krieger, Pandis, Stertz, Peter, Kohn and Nenes.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Ghislain Motos (G)

Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Aline Schaub (A)

Environmental Chemistry Laboratory, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Shannon C David (SC)

Environmental Chemistry Laboratory, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Laura Costa (L)

Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Environmental Chemistry Laboratory, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Céline Terrettaz (C)

Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Environmental Chemistry Laboratory, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Christos Kaltsonoudis (C)

Center for The Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, Greece.

Irina Glas (I)

Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

Liviana K Klein (LK)

Institute for Atmospheric and Climate Science, ETH Zurich, Zurich, Switzerland.

Nir Bluvshtein (N)

Institute for Atmospheric and Climate Science, ETH Zurich, Zurich, Switzerland.

Beiping Luo (B)

Institute for Atmospheric and Climate Science, ETH Zurich, Zurich, Switzerland.

Kalliopi Violaki (K)

Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Marie O Pohl (MO)

Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

Walter Hugentobler (W)

Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Ulrich K Krieger (UK)

Institute for Atmospheric and Climate Science, ETH Zurich, Zurich, Switzerland.

Spyros N Pandis (SN)

Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Center for The Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, Greece.
Department of Chemical Engineering, University of Patras, Patras, Greece.

Silke Stertz (S)

Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

Thomas Peter (T)

Institute for Atmospheric and Climate Science, ETH Zurich, Zurich, Switzerland.

Tamar Kohn (T)

Environmental Chemistry Laboratory, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

Athanasios Nenes (A)

Laboratory of Atmospheric Processes and their Impacts, School of Architecture, Civil and Environmental Engineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Center for The Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, Greece.

Classifications MeSH