Silke Stertz

Affiliations

Institute of Medical Virology, University of Zurich, 8057 Zurich, Switzerland. Electronic address: stertz.silke@virology.uzh.ch.

Publications (27)

Entry of influenza A virus into host cells - recent progress and remaining challenges.

Current opinion in virology

Avec: Milagros Sempere Borau , Silke Stertz

Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.

ACS infectious diseases

Avec: Marie O Pohl , Laura Martin-Sancho , Ranjala Ratnayake , Kris M White , Laura Riva , Qi-Yin Chen , Gauthier Lieber , Idoia Busnadiego , Xin Yin , Samuel Lin , Yuan Pu , Lars Pache , Romel Rosales , Marion Déjosez , Yiren Qin , Paul D De Jesus , Anne Beall , Sunnie Yoh , Benjamin G Hale , Thomas P Zwaka , Naoko Matsunaga , Adolfo García-Sastre , Silke Stertz , Sumit K Chanda , Hendrik Luesch

Inactivation mechanisms of influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS.

mSphere

Avec: Shannon C David , Oscar Vadas , Irina Glas , Aline Schaub , Beiping Luo , Giovanni D'angelo , Jonathan Paz Montoya , Nir Bluvshtein , Walter Hugentobler , Liviana K Klein , Ghislain Motos , Marie Pohl , Kalliopi Violaki , Athanasios Nenes , Ulrich K Krieger , Silke Stertz , Thomas Peter , Tamar Kohn

Interferon system deficiencies exacerbating severe pandemic virus infections.

Trends in microbiology

Avec: Silke Stertz , Benjamin G Hale

An antiviral trap made of protein nanofibrils and iron oxyhydroxide nanoparticles.

Nature nanotechnology

Avec: Archana Palika , Antonius Armanious , Akram Rahimi , Chiara Medaglia , Matteo Gasbarri , Stephan Handschin , Antonella Rossi , Marie O Pohl , Idoia Busnadiego , Christian Gübeli , Ravi B Anjanappa , Sreenath Bolisetty , Mohammad Peydayesh , Silke Stertz , Benjamin G Hale , Caroline Tapparel , Francesco Stellacci , Raffaele Mezzenga

Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation.

Nature communications

Avec: Patricia Domingues , Davide Eletto , Carsten Magnus , Hannah L Turkington , Stefan Schmutz , Osvaldo Zagordi , Matthias Lenk , Martin Beer , Silke Stertz , Benjamin G Hale

Breaking the Convention: Sialoglycan Variants, Coreceptors, and Alternative Receptors for Influenza A Virus Entry.

Journal of virology

Avec: Umut Karakus , Marie O Pohl , Silke Stertz

TIGIT limits immune pathology during viral infections.

Nature communications

Avec: Michelle Schorer , Nikolas Rakebrandt , Katharina Lambert , Annika Hunziker , Katharina Pallmer , Annette Oxenius , Anja Kipar , Silke Stertz , Nicole Joller

The neuraminidase activity of influenza A virus determines the strain-specific sensitivity to neutralization by respiratory mucus.

Journal of virology

Avec: Alena N Iseli , Marie O Pohl , Irina Glas , Elisabeth Gaggioli , Patricia Martínez-Barragán , Shannon C David , Aline Schaub , Beiping Luo , Liviana K Klein , Nir Bluvshtein , Kalliopi Violaki , Ghislain Motos , Walter Hugentobler , Athanasios Nenes , Ulrich K Krieger , Thomas Peter , Tamar Kohn , Silke Stertz

Antiviral potential of 3'-sialyllactose- and 6'-sialyllactose-conjugated dendritic polymers against human and avian influenza viruses.

Scientific reports

Avec: Sira Carolin Günther , Julian David Maier , Janine Vetter , Nikita Podvalnyy , Nikolay Khanzhin , Thierry Hennet , Silke Stertz

Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential.

mSphere

Avec: Eva E Spieler , Eva Moritz , Silke Stertz , Benjamin G Hale

MHC class II proteins mediate cross-species entry of bat influenza viruses.

Nature

Avec: Umut Karakus , Thiprampai Thamamongood , Kevin Ciminski , Wei Ran , Sira C Günther , Marie O Pohl , Davide Eletto , Csaba Jeney , Donata Hoffmann , Sven Reiche , Jan Schinköthe , Reiner Ulrich , Julius Wiener , Michael G B Hayes , Max W Chang , Annika Hunziker , Emilio Yángüez , Teresa Aydillo , Florian Krammer , Josua Oderbolz , Matthias Meier , Annette Oxenius , Anne Halenius , Gert Zimmer , Christopher Benner , Benjamin G Hale , Adolfo García-Sastre , Martin Beer , Martin Schwemmle , Silke Stertz

Combined computational and cellular screening identifies synergistic inhibition of SARS-CoV-2 by lenvatinib and remdesivir.

The Journal of general virology

Avec: Marie O Pohl , Idoia Busnadiego , Francesco Marrafino , Lars Wiedmer , Annika Hunziker , Sonja Fernbach , Irina Glas , Elena V Moroz-Omori , Benjamin G Hale , Amedeo Caflisch , Silke Stertz

Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria.

Journal of virology

Avec: Shannon C David , Aline Schaub , Céline Terrettaz , Ghislain Motos , Laura J Costa , Daniel S Nolan , Marta Augugliaro , Htet Kyi Wynn , Irina Glas , Marie O Pohl , Liviana K Klein , Beiping Luo , Nir Bluvshtein , Kalliopi Violaki , Walter Hugentobler , Ulrich K Krieger , Thomas Peter , Silke Stertz , Athanasios Nenes , Tamar Kohn

Impact of organic compounds on the stability of influenza A virus in deposited 1-μL droplets.

mSphere

Avec: Aline Schaub , Shannon C David , Irina Glas , Liviana K Klein , Kalliopi Violaki , Céline Terrettaz , Ghislain Motos , Nir Bluvshtein , Beiping Luo , Marie Pohl , Walter Hugentobler , Athanasios Nenes , Ulrich K Krieger , Thomas Peter , Silke Stertz , Tamar Kohn

SARS-CoV-2 variants reveal features critical for replication in primary human cells.

PLoS biology

Avec: Marie O Pohl , Idoia Busnadiego , Verena Kufner , Irina Glas , Umut Karakus , Stefan Schmutz , Maryam Zaheri , Irene Abela , Alexandra Trkola , Michael Huber , Silke Stertz , Benjamin G Hale

IFITM3 incorporation sensitizes influenza A virus to antibody-mediated neutralization.

The Journal of experimental medicine

Avec: Caroline Lanz , Michael Schotsaert , Carsten Magnus , Umut Karakus , Annika Hunziker , Milagros Sempere Borau , Carles Martínez-Romero , Eva E Spieler , Sira C Günther , Eva Moritz , Benjamin G Hale , Alexandra Trkola , Adolfo García-Sastre , Silke Stertz

Unraveling virus-induced cellular signaling cascades by label-free quantitative phosphoproteomics.

STAR protocols

Avec: Annika Hunziker , Silke Stertz

Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense.

Cell reports

Avec: Sonja Fernbach , Eva E Spieler , Idoia Busnadiego , Umut Karakus , Anouk Lkharrazi , Silke Stertz , Benjamin G Hale

Expiratory Aerosol pH: The Overlooked Driver of Airborne Virus Inactivation.

Environmental science & technology

Avec: Beiping Luo , Aline Schaub , Irina Glas , Liviana K Klein , Shannon C David , Nir Bluvshtein , Kalliopi Violaki , Ghislain Motos , Marie O Pohl , Walter Hugentobler , Athanasios Nenes , Ulrich K Krieger , Silke Stertz , Thomas Peter , Tamar Kohn

H19 influenza A virus exhibits species-specific MHC class II receptor usage.

Cell host & microbe

Avec: Umut Karakus , Ignacio Mena , Jithesh Kottur , Sara S El Zahed , Rocío Seoane , Soner Yildiz , Leanne Chen , Magdalena Plancarte , LeAnn Lindsay , Rebecca Halpin , Timothy B Stockwell , David E Wentworth , Geert-Jan Boons , Florian Krammer , Silke Stertz , Walter Boyce , Robert P de Vries , Aneel K Aggarwal , Adolfo García-Sastre

Antiviral Activity of Type I, II, and III Interferons Counterbalances ACE2 Inducibility and Restricts SARS-CoV-2.

mBio

Avec: Idoia Busnadiego , Sonja Fernbach , Marie O Pohl , Umut Karakus , Michael Huber , Alexandra Trkola , Silke Stertz , Benjamin G Hale

Phosphoproteomic profiling of influenza virus entry reveals infection-triggered filopodia induction counteracted by dynamic cortactin phosphorylation.

Cell reports

Avec: Annika Hunziker , Irina Glas , Marie O Pohl , Silke Stertz

Proteomic Identification of Potential Target Proteins of Cathepsin W for Its Development as a Drug Target for Influenza.

Microbiology spectrum

Avec: Sira C Günther , Carles Martínez-Romero , Milagros Sempere Borau , Christine T N Pham , Adolfo García-Sastre , Silke Stertz

MHC class II proteins mediate sialic acid independent entry of human and avian H2N2 influenza A viruses.

Nature microbiology

Avec: Umut Karakus , Milagros Sempere Borau , Patricia Martínez-Barragán , Josephine von Kempis , Soner Yildiz , Laura M Arroyo-Fernández , Marie O Pohl , Julia A Steiger , Irina Glas , Annika Hunziker , Adolfo García-Sastre , Silke Stertz

Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition.

Frontiers in microbiology

Avec: Ghislain Motos , Aline Schaub , Shannon C David , Laura Costa , Céline Terrettaz , Christos Kaltsonoudis , Irina Glas , Liviana K Klein , Nir Bluvshtein , Beiping Luo , Kalliopi Violaki , Marie O Pohl , Walter Hugentobler , Ulrich K Krieger , Spyros N Pandis , Silke Stertz , Thomas Peter , Tamar Kohn , Athanasios Nenes

Salt Supersaturation as an Accelerator of Influenza A Virus Inactivation in 1 μL Droplets.

Environmental science & technology

Avec: Aline Schaub , Beiping Luo , Shannon C David , Irina Glas , Liviana K Klein , Laura Costa , Céline Terrettaz , Nir Bluvshtein , Ghislain Motos , Kalliopi Violaki , Marie O Pohl , Walter Hugentobler , Athanasios Nenes , Silke Stertz , Ulrich K Krieger , Thomas Peter , Tamar Kohn

Réseau de co-auteurs

Marie O Pohl 14 collaborations

Benjamin G Hale 11 collaborations

Irina Glas 11 collaborations

Umut Karakus 8 collaborations

Shannon C David 7 collaborations

Aline Schaub 7 collaborations

Beiping Luo 7 collaborations

Nir Bluvshtein 7 collaborations

Walter Hugentobler 7 collaborations

Liviana K Klein 7 collaborations

Ghislain Motos 7 collaborations

Kalliopi Violaki 7 collaborations

Athanasios Nenes 7 collaborations

Ulrich K Krieger 7 collaborations

Thomas Peter 7 collaborations

Tamar Kohn 7 collaborations

Annika Hunziker 7 collaborations

Idoia Busnadiego 6 collaborations

Adolfo García-Sastre 6 collaborations

Milagros Sempere Borau 4 collaborations

Céline Terrettaz 4 collaborations

Eva E Spieler 3 collaborations

Sira C Günther 3 collaborations

Sonja Fernbach 3 collaborations

Alexandra Trkola 3 collaborations

Marie Pohl 2 collaborations

Davide Eletto 2 collaborations

Carsten Magnus 2 collaborations

Stefan Schmutz 2 collaborations

Martin Beer 2 collaborations

Annette Oxenius 2 collaborations

Patricia Martínez-Barragán 2 collaborations

Eva Moritz 2 collaborations

Florian Krammer 2 collaborations

Michael Huber 2 collaborations

Carles Martínez-Romero 2 collaborations

Soner Yildiz 2 collaborations

Laura Costa 2 collaborations

Laura Martin-Sancho 1 collaboration

Ranjala Ratnayake 1 collaboration

Kris M White 1 collaboration

Laura Riva 1 collaboration

Qi-Yin Chen 1 collaboration

Gauthier Lieber 1 collaboration

Xin Yin 1 collaboration

Samuel Lin 1 collaboration

Yuan Pu 1 collaboration

Lars Pache 1 collaboration

Romel Rosales 1 collaboration

Marion Déjosez 1 collaboration

Yiren Qin 1 collaboration

Paul D De Jesus 1 collaboration

Anne Beall 1 collaboration

Sunnie Yoh 1 collaboration

Thomas P Zwaka 1 collaboration

Naoko Matsunaga 1 collaboration

Sumit K Chanda 1 collaboration

Hendrik Luesch 1 collaboration

Oscar Vadas 1 collaboration

Giovanni D'angelo 1 collaboration

Jonathan Paz Montoya 1 collaboration

Archana Palika 1 collaboration

Antonius Armanious 1 collaboration

Akram Rahimi 1 collaboration

Chiara Medaglia 1 collaboration

Matteo Gasbarri 1 collaboration

Stephan Handschin 1 collaboration

Antonella Rossi 1 collaboration

Christian Gübeli 1 collaboration

Ravi B Anjanappa 1 collaboration

Sreenath Bolisetty 1 collaboration

Mohammad Peydayesh 1 collaboration

Caroline Tapparel 1 collaboration

Francesco Stellacci 1 collaboration

Raffaele Mezzenga 1 collaboration

Patricia Domingues 1 collaboration

Hannah L Turkington 1 collaboration

Osvaldo Zagordi 1 collaboration

Matthias Lenk 1 collaboration

Michelle Schorer 1 collaboration

Nikolas Rakebrandt 1 collaboration

Katharina Lambert 1 collaboration

Katharina Pallmer 1 collaboration

Anja Kipar 1 collaboration

Nicole Joller 1 collaboration

Alena N Iseli 1 collaboration

Elisabeth Gaggioli 1 collaboration

Sira Carolin Günther 1 collaboration

Julian David Maier 1 collaboration

Janine Vetter 1 collaboration

Nikita Podvalnyy 1 collaboration

Nikolay Khanzhin 1 collaboration

Thierry Hennet 1 collaboration

Thiprampai Thamamongood 1 collaboration

Kevin Ciminski 1 collaboration

Wei Ran 1 collaboration

Csaba Jeney 1 collaboration

Donata Hoffmann 1 collaboration

Sven Reiche 1 collaboration

Jan Schinköthe 1 collaboration

Reiner Ulrich 1 collaboration

Julius Wiener 1 collaboration

Michael G B Hayes 1 collaboration

Max W Chang 1 collaboration

Emilio Yángüez 1 collaboration

Teresa Aydillo 1 collaboration

Josua Oderbolz 1 collaboration

Matthias Meier 1 collaboration

Anne Halenius 1 collaboration

Gert Zimmer 1 collaboration

Christopher Benner 1 collaboration

Martin Schwemmle 1 collaboration

Francesco Marrafino 1 collaboration

Lars Wiedmer 1 collaboration

Elena V Moroz-Omori 1 collaboration

Amedeo Caflisch 1 collaboration

Laura J Costa 1 collaboration

Daniel S Nolan 1 collaboration

Marta Augugliaro 1 collaboration

Htet Kyi Wynn 1 collaboration

Verena Kufner 1 collaboration

Maryam Zaheri 1 collaboration

Irene Abela 1 collaboration

Caroline Lanz 1 collaboration

Michael Schotsaert 1 collaboration

Anouk Lkharrazi 1 collaboration

Ignacio Mena 1 collaboration

Jithesh Kottur 1 collaboration

Sara S El Zahed 1 collaboration

Rocío Seoane 1 collaboration

Leanne Chen 1 collaboration

Magdalena Plancarte 1 collaboration

LeAnn Lindsay 1 collaboration

Rebecca Halpin 1 collaboration

Timothy B Stockwell 1 collaboration

David E Wentworth 1 collaboration

Geert-Jan Boons 1 collaboration

Walter Boyce 1 collaboration

Robert P de Vries 1 collaboration

Aneel K Aggarwal 1 collaboration

Christine T N Pham 1 collaboration

Josephine von Kempis 1 collaboration

Laura M Arroyo-Fernández 1 collaboration

Julia A Steiger 1 collaboration

Christos Kaltsonoudis 1 collaboration

Spyros N Pandis 1 collaboration