Claire E Eyers

Affiliations

Department of Biochemistry, Centre for Proteome Research, Institute of Integrative Biology, University of Liverpool, Liverpool, UK. ceyers@liverpool.ac.uk.

Publications (33)

Ion Mobility-Mass Spectrometry to Evaluate the Effects of Protein Modification or Small Molecule Binding on Protein Dynamics.

Methods in molecular biology (Clifton, N.J.)

Avec: Lauren J Tomlinson ,

Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation.

The EMBO journal

Avec: Gemma Hardman , Simon Perkins , Philip J Brownridge , Christopher J Clarke , Dominic P Byrne , Amy E Campbell , Anton Kalyuzhnyy , Ashleigh Myall , Patrick A Eyers , Andrew R Jones ,

Proteomic analysis of dietary restriction in yeast reveals a role for Hsp26 in replicative lifespan extension.

The Biochemical journal

Avec: Richard Campion , Leanne Bloxam , Kimberley Burrow , Philip J Brownridge , Daniel R Pentland , Patricia Thomas , Campbell W Gourlay , Jeff W Barclay , Alan Morgan

Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential.

Nature communications

Avec: Bjoern Meyer , Jeanne Chiaravalli , Stacy Gellenoncourt , Philip Brownridge , Dominic P Bryne , Leonard A Daly , Arturas Grauslys , Marius Walter , Fabrice Agou , Lisa A Chakrabarti , Charles S Craik , Patrick A Eyers , Yann Gambin , Andrew R Jones , Emma Sierecki , Eric Verdin , Marco Vignuzzi , Edward Emmott

Regulation of CHK1 inhibitor resistance by a c-Rel and USP1 dependent pathway.

The Biochemical journal

Avec: Jill E Hunter , Amy E Campbell , Nicola L Hannaway , Scott Kerridge , Saimir Luli , Jacqueline A Butterworth , Helene Sellier , Reshmi Mukherjee , Nikita Dhillon , Praveen D Sudhindar , Ruchi Shukla , Philip J Brownridge , Hayden L Bell , Jonathan Coxhead , Leigh Taylor , Peter Leary , Megan S R Hasoon , Ian Collins , Michelle D Garrett , Neil D Perkins

Myoblast Phosphoproteomics as a Tool to Investigate Global Signaling Events During Myogenesis.

Methods in molecular biology (Clifton, N.J.)

Avec: Fiona K Jones , Gemma E Hardman , Samantha Ferries , Addolorata Pisconti

High-Throughput Characterization of Histidine Phosphorylation Sites Using UPAX and Tandem Mass Spectrometry.

Methods in molecular biology (Clifton, N.J.)

Avec: Gemma Hardman ,

Custom Workflow for the Confident Identification of Sulfotyrosine-Containing Peptides and Their Discrimination from Phosphopeptides.

Journal of proteome research

Avec: Leonard A Daly , Dominic P Byrne , Simon Perkins , Philip J Brownridge , Euan McDonnell , Andrew R Jones , Patrick A Eyers ,

Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2.

The Biochemical journal

Avec: Dominic P Byrne , Safal Shrestha , Leonard A Daly , Vanessa Marensi , Krithika Ramakrishnan , Natarajan Kannan , Patrick A Eyers

Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases.

bioRxiv : the preprint server for biology

Avec: Aarya Venkat , Grace Watterson , Dominic P Byrne , Brady O'Boyle , Safal Shrestha , Nathan Gravel , Emma E Fairweather , Leonard A Daly , Claire Bunn , Wayland Yeung , Ishan Aggarwal , Samiksha Katiyar , Patrick A Eyers , Natarajan Kannan

DNA Binding and Phosphorylation Regulate the Core Structure of the NF-κB p50 Transcription Factor.

Journal of the American Society for Mass Spectrometry

Avec: Matthias Vonderach , Dominic P Byrne , Perdita E Barran , Patrick A Eyers ,

Mislocalization of protein kinase A drives pathology in Cushing's syndrome.

Cell reports

Avec: Mitchell H Omar , Dominic P Byrne , Kiana N Jones , Tyler M Lakey , Kerrie B Collins , Kyung-Soon Lee , Leonard A Daly , Katherine A Forbush , Ho-Tak Lau , Martin Golkowski , G Stanley McKnight , David T Breault , Anne-Marie Lefrançois-Martinez , Antoine Martinez , Geoffrey S Baird , Shao-En Ong , F Donelson Smith , Patrick A Eyers , John D Scott

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells.

The Biochemical journal

Avec: Jill E Hunter , Amy E Campbell , Scott Kerridge , Callum Fraser , Nicola L Hannaway , Saimir Luli , Iglika Ivanova , Philip J Brownridge , Jonathan Coxhead , Leigh Taylor , Peter Leary , Megan S R Hasoon , Neil D Perkins

Top-Down Proteomics and the Challenges of True Proteoform Characterization.

Journal of proteome research

Avec: Allen Po ,

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms.

bioRxiv : the preprint server for biology

Avec: George N Bendzunas , Dominic P Byrne , Safal Shrestha , Leonard A Daly , Sally O Oswald , Samiksha Katiyar , Aarya Venkat , Wayland Yeung , Patrick A Eyers , Natarajan Kannan

Mass Spectrometric Analysis of the Active Site Tryptic Peptide of Recombinant

Chemical research in toxicology

Avec: Rasha Abdelhady , Pattama Senthong , Onrapak Reamtong , Elizabeth Cowley , Luca Cannizzaro , Joanna Stimpson , Kathleen Cain , Oliver J Wilkinson , Nicholas H Williams , Perdita E Barran , Geoffrey P Margison , David M Williams , Andrew C Povey

Temporal modulation of the NF-κB RelA network in response to different types of DNA damage.

The Biochemical journal

Avec: Amy E Campbell , Catarina Ferraz Franco , Ling-I Su , Emma K Corbin , Simon Perkins , Anton Kalyuzhnyy , Andrew R Jones , Philip J Brownridge , Neil D Perkins ,

Determination of Phosphohistidine Stoichiometry in Histidine Kinases by Intact Mass Spectrometry.

Methods in molecular biology (Clifton, N.J.)

Avec: Lauren J Tomlinson , Alice K M Clubbs Coldron , Patrick A Eyers ,

Advancing Solutions to the Carbohydrate Sequencing Challenge.

Journal of the American Chemical Society

Avec: Christopher J Gray , Lukasz G Migas , Perdita E Barran , Kevin Pagel , Peter H Seeberger , Geert-Jan Boons , Nicola L B Pohl , Isabelle Compagnon , Göran Widmalm , Sabine L Flitsch

Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α.

Science signaling

Avec: Leonard A Daly , Philip J Brownridge , Michael Batie , Sonia Rocha , Violaine Sée ,

Profiling the Human Phosphoproteome to Estimate the True Extent of Protein Phosphorylation.

Journal of proteome research

Avec: Anton Kalyuzhnyy , Patrick A Eyers , Emily Bowler-Barnett , Maria J Martin , Zhi Sun , Eric W Deutsch , Andrew R Jones

Dissection of schistosome tissues under LC-MS compatible preservative conditions for quantitative proteomics.

Rapid communications in mass spectrometry : RCM

Avec: Leandro Xavier Neves , R Alan Wilson , Philip Brownridge , Stephen W Holman , Victoria M Harman , Robert J Beynon , William Castro-Borges

Quantitative Proteomics of Enriched Esophageal and Gut Tissues from the Human Blood Fluke

Journal of proteome research

Avec: Leandro X Neves , R Alan Wilson , Philip Brownridge , Victoria M Harman , Stephen W Holman , Robert J Beynon , Ricardo DeMarco , William Castro-Borges

Covalent Aurora A regulation by the metabolic integrator coenzyme A.

Redox biology

Avec: Yugo Tsuchiya , Dominic P Byrne , Selena G Burgess , Jenny Bormann , Jovana Baković , Yueyang Huang , Alexander Zhyvoloup , Bess Yi Kun Yu , Sew Peak-Chew , Trang Tran , Fiona Bellany , Alethea B Tabor , Aw Edith Chan , Lalitha Guruprasad , Oleg Garifulin , Valeriy Filonenko , Matthias Vonderach , Samantha Ferries , John Carroll , Mark Skehel , Richard Bayliss , Patrick A Eyers , Ivan Gout

Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity.

Science signaling

Avec: Dominic P Byrne , Safal Shrestha , Martin Galler , Min Cao , Leonard A Daly , Amy E Campbell , Elizabeth A Veal , Natarajan Kannan , Patrick A Eyers

Use of the Polo-like kinase 4 (PLK4) inhibitor centrinone to investigate intracellular signalling networks using SILAC-based phosphoproteomics.

The Biochemical journal

Avec: Dominic P Byrne , Christopher J Clarke , Philip J Brownridge , Anton Kalyuzhnyy , Simon Perkins , Amy Campbell , David Mason , Andrew R Jones , Patrick A Eyers ,

Exploring the Conformational Landscape and Stability of Aurora A Using Ion-Mobility Mass Spectrometry and Molecular Modeling.

Journal of the American Society for Mass Spectrometry

Avec: Lauren J Tomlinson , Matthew Batchelor , Joscelyn Sarsby , Dominic P Byrne , Philip J Brownridge , Richard Bayliss , Patrick A Eyers ,

Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs.

Science advances

Avec: Mitchell H Omar , Dominic P Byrne , Safal Shrestha , Tyler M Lakey , Kyung-Soon Lee , Sophia M Lauer , Kerrie B Collins , Leonard A Daly , Geoffrey S Baird , Shao-En Ong , Natarajan Kannan , Patrick A Eyers , John D Scott

Mechanism of glycogen synthase inactivation and interaction with glycogenin.

Nature communications

Avec: Laura Marr , Dipsikha Biswas , Leonard A Daly , Christopher Browning , Sarah C M Vial , Daniel P Maskell , Catherine Hudson , Jay A Bertrand , John Pollard , Neil A Ranson , Heena Khatter , Kei Sakamoto , Elton Zeqiraj

Attaching protein-adsorbing silica particles to the surface of cotton substrates for bioaerosol capture including SARS-CoV-2.

Nature communications

Avec: Kieran Collings , Cedric Boisdon , Tung-Ting Sham , Kevin Skinley , Hyun-Kyung Oh , Tessa Prince , Adham Ahmed , Shaun H Pennington , Philip J Brownridge , Thomas Edwards , Giancarlo A Biagini , Amanda Lamb , Peter Myers , Simon Maher

Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases.

eLife

Considerations for defining +80 Da mass shifts in mass spectrometry-based proteomics: phosphorylation and beyond.

Chemical communications (Cambridge, England)

Avec: Leonard A Daly , Christopher J Clarke , Allen Po , Sally O Oswald ,

Rubisco packaging and stoichiometric composition of a native β-carboxysome.

bioRxiv : the preprint server for biology

Avec: Yaqi Sun , Yuewen Sheng , Tao Ni , Xingwu Ge , Joscelyn Sarsby , Philip J Brownridge , Kang Li , Nathan Hardenbrook , Gregory F Dykes , Nichola Rockliffe , Peijun Zhang , Lu-Ning Liu

Réseau de co-auteurs

Patrick A Eyers 16 collaborations

Dominic P Byrne 13 collaborations

Leonard A Daly 12 collaborations

Philip J Brownridge 11 collaborations

Andrew R Jones 6 collaborations

Safal Shrestha 6 collaborations

Natarajan Kannan 6 collaborations

Amy E Campbell 5 collaborations

Simon Perkins 4 collaborations

Anton Kalyuzhnyy 4 collaborations

Lauren J Tomlinson 3 collaborations

Christopher J Clarke 3 collaborations

Philip Brownridge 3 collaborations

Neil D Perkins 3 collaborations

Aarya Venkat 3 collaborations

Wayland Yeung 3 collaborations

Samiksha Katiyar 3 collaborations

Perdita E Barran 3 collaborations

Gemma Hardman 2 collaborations

Jill E Hunter 2 collaborations

Nicola L Hannaway 2 collaborations

Scott Kerridge 2 collaborations

Saimir Luli 2 collaborations

Jonathan Coxhead 2 collaborations

Leigh Taylor 2 collaborations

Peter Leary 2 collaborations

Megan S R Hasoon 2 collaborations

Samantha Ferries 2 collaborations

Grace Watterson 2 collaborations

Brady O'Boyle 2 collaborations

Nathan Gravel 2 collaborations

Emma E Fairweather 2 collaborations

Claire Bunn 2 collaborations

Ishan Aggarwal 2 collaborations

Matthias Vonderach 2 collaborations

Mitchell H Omar 2 collaborations

Tyler M Lakey 2 collaborations

Kerrie B Collins 2 collaborations

Kyung-Soon Lee 2 collaborations

Geoffrey S Baird 2 collaborations

Shao-En Ong 2 collaborations

John D Scott 2 collaborations

Allen Po 2 collaborations

Sally O Oswald 2 collaborations

R Alan Wilson 2 collaborations

Stephen W Holman 2 collaborations

Victoria M Harman 2 collaborations

Robert J Beynon 2 collaborations

William Castro-Borges 2 collaborations

Richard Bayliss 2 collaborations

Joscelyn Sarsby 2 collaborations

Ashleigh Myall 1 collaboration

Richard Campion 1 collaboration

Leanne Bloxam 1 collaboration

Kimberley Burrow 1 collaboration

Daniel R Pentland 1 collaboration

Patricia Thomas 1 collaboration

Campbell W Gourlay 1 collaboration

Jeff W Barclay 1 collaboration

Alan Morgan 1 collaboration

Bjoern Meyer 1 collaboration

Jeanne Chiaravalli 1 collaboration

Stacy Gellenoncourt 1 collaboration

Dominic P Bryne 1 collaboration

Arturas Grauslys 1 collaboration

Marius Walter 1 collaboration

Fabrice Agou 1 collaboration

Lisa A Chakrabarti 1 collaboration

Charles S Craik 1 collaboration

Yann Gambin 1 collaboration

Emma Sierecki 1 collaboration

Eric Verdin 1 collaboration

Marco Vignuzzi 1 collaboration

Edward Emmott 1 collaboration

Jacqueline A Butterworth 1 collaboration

Helene Sellier 1 collaboration

Reshmi Mukherjee 1 collaboration

Nikita Dhillon 1 collaboration

Praveen D Sudhindar 1 collaboration

Ruchi Shukla 1 collaboration

Hayden L Bell 1 collaboration

Ian Collins 1 collaboration

Michelle D Garrett 1 collaboration

Fiona K Jones 1 collaboration

Gemma E Hardman 1 collaboration

Addolorata Pisconti 1 collaboration

Euan McDonnell 1 collaboration

Vanessa Marensi 1 collaboration

Krithika Ramakrishnan 1 collaboration

Kiana N Jones 1 collaboration

Katherine A Forbush 1 collaboration

Ho-Tak Lau 1 collaboration

Martin Golkowski 1 collaboration

G Stanley McKnight 1 collaboration

David T Breault 1 collaboration

Anne-Marie Lefrançois-Martinez 1 collaboration

Antoine Martinez 1 collaboration

F Donelson Smith 1 collaboration

Callum Fraser 1 collaboration

Iglika Ivanova 1 collaboration

George N Bendzunas 1 collaboration

Rasha Abdelhady 1 collaboration

Pattama Senthong 1 collaboration

Onrapak Reamtong 1 collaboration

Elizabeth Cowley 1 collaboration

Luca Cannizzaro 1 collaboration

Joanna Stimpson 1 collaboration

Kathleen Cain 1 collaboration

Oliver J Wilkinson 1 collaboration

Nicholas H Williams 1 collaboration

Geoffrey P Margison 1 collaboration

David M Williams 1 collaboration

Andrew C Povey 1 collaboration

Catarina Ferraz Franco 1 collaboration

Ling-I Su 1 collaboration

Emma K Corbin 1 collaboration

Alice K M Clubbs Coldron 1 collaboration

Christopher J Gray 1 collaboration

Lukasz G Migas 1 collaboration

Kevin Pagel 1 collaboration

Peter H Seeberger 1 collaboration

Geert-Jan Boons 1 collaboration

Nicola L B Pohl 1 collaboration

Isabelle Compagnon 1 collaboration

Göran Widmalm 1 collaboration

Sabine L Flitsch 1 collaboration

Michael Batie 1 collaboration

Sonia Rocha 1 collaboration

Violaine Sée 1 collaboration

Emily Bowler-Barnett 1 collaboration

Maria J Martin 1 collaboration

Zhi Sun 1 collaboration

Eric W Deutsch 1 collaboration

Leandro Xavier Neves 1 collaboration

Leandro X Neves 1 collaboration

Ricardo DeMarco 1 collaboration

Yugo Tsuchiya 1 collaboration

Selena G Burgess 1 collaboration

Jenny Bormann 1 collaboration

Jovana Baković 1 collaboration

Yueyang Huang 1 collaboration

Alexander Zhyvoloup 1 collaboration

Bess Yi Kun Yu 1 collaboration

Sew Peak-Chew 1 collaboration

Trang Tran 1 collaboration

Fiona Bellany 1 collaboration

Alethea B Tabor 1 collaboration

Aw Edith Chan 1 collaboration

Lalitha Guruprasad 1 collaboration

Oleg Garifulin 1 collaboration

Valeriy Filonenko 1 collaboration

John Carroll 1 collaboration

Mark Skehel 1 collaboration

Ivan Gout 1 collaboration

Martin Galler 1 collaboration

Min Cao 1 collaboration

Elizabeth A Veal 1 collaboration

Amy Campbell 1 collaboration

David Mason 1 collaboration

Matthew Batchelor 1 collaboration

Sophia M Lauer 1 collaboration

Laura Marr 1 collaboration

Dipsikha Biswas 1 collaboration

Christopher Browning 1 collaboration

Sarah C M Vial 1 collaboration

Daniel P Maskell 1 collaboration

Catherine Hudson 1 collaboration

Jay A Bertrand 1 collaboration

John Pollard 1 collaboration

Neil A Ranson 1 collaboration

Heena Khatter 1 collaboration

Kei Sakamoto 1 collaboration

Elton Zeqiraj 1 collaboration

Kieran Collings 1 collaboration

Cedric Boisdon 1 collaboration

Tung-Ting Sham 1 collaboration

Kevin Skinley 1 collaboration

Hyun-Kyung Oh 1 collaboration

Tessa Prince 1 collaboration

Adham Ahmed 1 collaboration

Shaun H Pennington 1 collaboration

Thomas Edwards 1 collaboration

Giancarlo A Biagini 1 collaboration

Amanda Lamb 1 collaboration

Peter Myers 1 collaboration

Simon Maher 1 collaboration

Yaqi Sun 1 collaboration

Yuewen Sheng 1 collaboration

Tao Ni 1 collaboration

Xingwu Ge 1 collaboration

Kang Li 1 collaboration

Nathan Hardenbrook 1 collaboration

Gregory F Dykes 1 collaboration

Nichola Rockliffe 1 collaboration

Peijun Zhang 1 collaboration

Lu-Ning Liu 1 collaboration