Frédéric Darios

Affiliations

1Sorbonne Université, UPMC Univ Paris 06, UMR S 1127, F-75013 Paris, France.
2Inserm, U1127, F-75013 Paris, France.
3CNRS, UMR 7225, F-75013 Paris, France.
4Institut du Cerveau et de la Moelle Epinière, ICM, F-75013 Paris, France.

ORCID: 0000-0001-9800-5990

Publications (11)

Loss of spatacsin impairs cholesterol trafficking and calcium homeostasis.

Communications biology

Avec: Maxime Boutry , Alexandre Pierga , Raphaël Matusiak , Julien Branchu , Marc Houllegatte , Yoan Ibrahim , Elise Balse , Khalid-Hamid El Hachimi , Alexis Brice , Giovanni Stevanin ,

Lipids in the Physiopathology of Hereditary Spastic Paraplegias.

Frontiers in neuroscience

Avec: Fanny Mochel , Giovanni Stevanin

Impairment of Lysosome Function and Autophagy in Rare Neurodegenerative Diseases.

Journal of molecular biology

Avec: Giovanni Stevanin

Clinically approved immunomodulators ameliorate behavioral changes in a mouse model of hereditary spastic paraplegia type 11.

Frontiers in neuroscience

Avec: Michaela Hörner , Sandy Popp , Julien Branchu , Giovanni Stevanin , Stephan Klebe , Janos Groh , Rudolf Martini

Genetics in hereditary spastic paraplegias: Essential but not enough.

Current opinion in neurobiology

Avec: Giulia Coarelli , Alexandra Durr

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.

PLoS biology

Avec: Alexandre Pierga , Raphaël Matusiak , Margaux Cauhapé , Julien Branchu , Lydia Danglot , Maxime Boutry ,

Decreasing ganglioside synthesis delays motor and cognitive symptom onset in Spg11 knockout mice.

Neurobiology of disease

Avec: Manon Fortier , Margaux Cauhapé , Suzie Buono , Julien Becker , Alexia Menuet , Julien Branchu , Ivana Ricca , Serena Mero , Karim Dorgham , Khalid-Hamid El Hachimi , Kostantin Dobrenis , Benoit Colsch , Dominic Samaroo , Morgan Devaux , Alexandra Durr , Giovanni Stevanin , Filippo M Santorelli , Sophie Colombo , Belinda Cowling ,

Implication of folate deficiency in CYP2U1 loss of function.

The Journal of experimental medicine

Avec: Claire Pujol , Anne Legrand , Livia Parodi , Priscilla Thomas , Fanny Mochel , Dario Saracino , Giulia Coarelli , Marijana Croon , Milica Popovic , Manon Valet , Nicolas Villain , Shahira Elshafie , Mahmoud Issa , Stephane Zuily , Mathilde Renaud , Cécilia Marelli-Tosi , Marine Legendre , Aurélien Trimouille , Isabelle Kemlin , Sophie Mathieu , Joseph G Gleeson , Foudil Lamari , Daniele Galatolo , Rana Alkouri , Chantal Tse , Diana Rodriguez , Claire Ewenczyk , Florence Fellmann , Thierry Kuntzer , Emilie Blond , Khalid H El Hachimi , Alexandre Seyer , Anastasia D Gazi , Patrick Giavalisco , Silvina Perin , Jean-Luc Boucher , Laurent Le Corre , Filippo M Santorelli , Cyril Goizet , Maha S Zaki , Serge Picaud , Arnaud Mourier , Sophie Marie Steculorum , Cyril Mignot , Alexandra Durr , Aleksandra Trifunovic , Giovanni Stevanin

Recent advances in understanding hereditary spastic paraplegias and emerging therapies.

Faculty reviews

Avec: Pauline Lallemant-Dudek , Frederic Darios , Alexandra Durr

Plasma neurofilament light chain predicts cerebellar atrophy and clinical progression in spinocerebellar ataxia.

Neurobiology of disease

Avec: Giulia Coarelli , Frederic Darios , Emilien Petit , Karim Dorgham , Isaac Adanyeguh , Elodie Petit , Alexis Brice , Fanny Mochel , Alexandra Durr

CNS-associated T-lymphocytes in a mouse model of Hereditary Spastic Paraplegia type 11 (SPG11) are therapeutic targets for established immunomodulators.

Experimental neurology

Avec: Michaela Hörner , Janos Groh , Dennis Klein , Winfried Ilg , Ludger Schöls , Sara Dos Santos , Anna Bergmann , Stephan Klebe , Margaux Cauhape , Julien Branchu , Khalid Hamid El Hachimi , Giovanni Stevanin , Rudolf Martini

Réseau de co-auteurs

Giovanni Stevanin 7 collaborations

Julien Branchu 5 collaborations

Alexandra Durr 5 collaborations

Fanny Mochel 3 collaborations

Giulia Coarelli 3 collaborations

Maxime Boutry 2 collaborations

Alexandre Pierga 2 collaborations

Raphaël Matusiak 2 collaborations

Khalid-Hamid El Hachimi 2 collaborations

Alexis Brice 2 collaborations

Michaela Hörner 2 collaborations

Stephan Klebe 2 collaborations

Janos Groh 2 collaborations

Rudolf Martini 2 collaborations

Margaux Cauhapé 2 collaborations

Karim Dorgham 2 collaborations

Filippo M Santorelli 2 collaborations

Frederic Darios 2 collaborations

Marc Houllegatte 1 collaboration

Yoan Ibrahim 1 collaboration

Elise Balse 1 collaboration

Sandy Popp 1 collaboration

Lydia Danglot 1 collaboration

Manon Fortier 1 collaboration

Suzie Buono 1 collaboration

Julien Becker 1 collaboration

Alexia Menuet 1 collaboration

Ivana Ricca 1 collaboration

Serena Mero 1 collaboration

Kostantin Dobrenis 1 collaboration

Benoit Colsch 1 collaboration

Dominic Samaroo 1 collaboration

Morgan Devaux 1 collaboration

Sophie Colombo 1 collaboration

Belinda Cowling 1 collaboration

Claire Pujol 1 collaboration

Anne Legrand 1 collaboration

Livia Parodi 1 collaboration

Priscilla Thomas 1 collaboration

Dario Saracino 1 collaboration

Marijana Croon 1 collaboration

Milica Popovic 1 collaboration

Manon Valet 1 collaboration

Nicolas Villain 1 collaboration

Shahira Elshafie 1 collaboration

Mahmoud Issa 1 collaboration

Stephane Zuily 1 collaboration

Mathilde Renaud 1 collaboration

Cécilia Marelli-Tosi 1 collaboration

Marine Legendre 1 collaboration

Aurélien Trimouille 1 collaboration

Isabelle Kemlin 1 collaboration

Sophie Mathieu 1 collaboration

Joseph G Gleeson 1 collaboration

Foudil Lamari 1 collaboration

Daniele Galatolo 1 collaboration

Rana Alkouri 1 collaboration

Chantal Tse 1 collaboration

Diana Rodriguez 1 collaboration

Claire Ewenczyk 1 collaboration

Florence Fellmann 1 collaboration

Thierry Kuntzer 1 collaboration

Emilie Blond 1 collaboration

Khalid H El Hachimi 1 collaboration

Alexandre Seyer 1 collaboration

Anastasia D Gazi 1 collaboration

Patrick Giavalisco 1 collaboration

Silvina Perin 1 collaboration

Jean-Luc Boucher 1 collaboration

Laurent Le Corre 1 collaboration

Cyril Goizet 1 collaboration

Maha S Zaki 1 collaboration

Serge Picaud 1 collaboration

Arnaud Mourier 1 collaboration

Sophie Marie Steculorum 1 collaboration

Cyril Mignot 1 collaboration

Aleksandra Trifunovic 1 collaboration

Pauline Lallemant-Dudek 1 collaboration

Emilien Petit 1 collaboration

Isaac Adanyeguh 1 collaboration

Elodie Petit 1 collaboration

Dennis Klein 1 collaboration

Winfried Ilg 1 collaboration

Ludger Schöls 1 collaboration

Sara Dos Santos 1 collaboration

Anna Bergmann 1 collaboration

Margaux Cauhape 1 collaboration

Khalid Hamid El Hachimi 1 collaboration