Adam R Karpf

Affiliations

Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, NE 68198-6805, USA.
Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198-6805, USA.

ORCID: 0000-0002-0866-0666

Publications (20)

PROTACs in Ovarian Cancer: Current Advancements and Future Perspectives.

International journal of molecular sciences

Avec: Makenzie Vorderbruggen , Carlos A Velázquez-Martínez , Amarnath Natarajan , Adam R Karpf

Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK.

Chemical biology & drug design

Avec: Sandeep Rana , Smit Kour , Yogesh A Sonawane , Caroline M Robb , Jacob I Contreras , Smitha Kizhake , Muhammad Zahid , Adam R Karpf , Amarnath Natarajan

Protein kinase RNA-activated controls mitotic progression and determines paclitaxel chemosensitivity through B-cell lymphoma 2 in ovarian cancer.

Oncogene

Avec: Ling Yin , Yongji Zeng , Renya Zeng , Yuanhong Chen , Tian-Li Wang , Kerry J Rodabaugh , Fang Yu , Amarnath Natarajan , Adam R Karpf , Jixin Dong

FOXM1: A Multifunctional Oncoprotein and Emerging Therapeutic Target in Ovarian Cancer.

Cancers

Avec: Cassie Liu , Carter J Barger , Adam R Karpf

Crosstalk between protein kinase C α and transforming growth factor β signaling mediated by Runx2 in intestinal epithelial cells.

The Journal of biological chemistry

Avec: Xinyue Li , Navneet Kaur , Mustafa Albahrani , Adam R Karpf , Adrian R Black , Jennifer D Black

NB compounds are potent and efficacious FOXM1 inhibitors in high-grade serous ovarian cancer cells.

Journal of ovarian research

Avec: Cassie Liu , Makenzie Vorderbruggen , Catalina Muñoz-Trujillo , Sung Hoon Kim , John A Katzenellenbogen , Benita S Katzenellenbogen , Adam R Karpf

Molecular cancer research : MCR

Avec: Joanna C Hillman , Elena M Pugacheva , Carter J Barger , Sirinapa Sribenja , Spencer Rosario , Mustafa Albahrani , Alexander M Truskinovsky , Aimee Stablewski , Song Liu , Dmitri I Loukinov , Gabriel E Zentner , Victor V Lobanenkov , Adam R Karpf , Michael J Higgins

In vivo modeling of metastatic human high-grade serous ovarian cancer in mice.

PLoS genetics

Avec: Olga Kim , Eun Young Park , David L Klinkebiel , Svetlana D Pack , Yong-Hyun Shin , Zied Abdullaev , Robert E Emerson , Donna M Coffey , Sun Young Kwon , Chad J Creighton , Sanghoon Kwon , Edmund C Chang , Theodore Chiang , Alexander N Yatsenko , Jeremy Chien , Dong-Joo Cheon , Yang Yang-Hartwich , Harikrishna Nakshatri , Kenneth P Nephew , Richard R Behringer , Facundo M Fernández , Chi-Heum Cho , Barbara Vanderhyden , Ronny Drapkin , Robert C Bast , Kathy D Miller , Adam R Karpf , Jaeyeon Kim

Spirocyclic dimer SpiD7 activates the unfolded protein response to selectively inhibit growth and induce apoptosis of cancer cells.

The Journal of biological chemistry

Avec: Smit Kour , Sandeep Rana , Sydney P Kubica , Smitha Kizhake , Mudassier Ahmad , Catalina Muñoz-Trujillo , David Klinkebiel , Sarbjit Singh , Jayapal Reddy Mallareddy , Surabhi Chandra , Nicholas T Woods , Adam R Karpf , Amarnath Natarajan

Ligand-installed polymeric nanocarriers for combination chemotherapy of EGFR-positive ovarian cancer.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Xinyuan Xi , Fan Lei , Keliang Gao , Jingjing Li , Rihe Liu , Adam R Karpf , Tatiana K Bronich

Global DNA Hypomethylation in Epithelial Ovarian Cancer: Passive Demethylation and Association with Genomic Instability.

Cancers

Avec: Wa Zhang , David Klinkebiel , Carter J Barger , Sanjit Pandey , Chittibabu Guda , Austin Miller , Stacey N Akers , Kunle Odunsi , Adam R Karpf

Targeting progesterone signaling prevents metastatic ovarian cancer.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Olga Kim , Eun Young Park , Sun Young Kwon , Sojin Shin , Robert E Emerson , Yong-Hyun Shin , Francesco J DeMayo , John P Lydon , Donna M Coffey , Shannon M Hawkins , Lawrence A Quilliam , Dong-Joo Cheon , Facundo M Fernández , Kenneth P Nephew , Adam R Karpf , Martin Widschwendter , Anil K Sood , Robert C Bast , Andrew K Godwin , Kathy D Miller , Chi-Heum Cho , Jaeyeon Kim

Co-regulation and function of

eLife

Avec: Carter J Barger , Linda Chee , Mustafa Albahrani , Catalina Munoz-Trujillo , Lidia Boghean , Connor Branick , Kunle Odunsi , Ronny Drapkin , Lee Zou , Adam R Karpf

Reprogramming of Ovarian Granulosa Cells by YAP1 Leads to Development of High-Grade Cancer with Mesenchymal Lineage and Serous Features.

Science bulletin

Avec: Xiangmin Lv , Chunbo He , Cong Huang , Guohua Hua , Xingcheng Chen , Barbara K Timm , Victoria M Maclin , Abigail A Haggerty , Shelly K Aust , Denae M Golden , Bhavana J Dave , Yun-An Tseng , Li Chen , Hongbo Wang , Peichao Chen , David L Klinkebiel , Adam R Karpf , Jixin Dong , Ronny I Drapkin , Bo R Rueda , John S Davis , Cheng Wang

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection.

Nature microbiology

Avec: Cortney E Heim , Megan E Bosch , Kelsey J Yamada , Amy L Aldrich , Sujata S Chaudhari , David Klinkebiel , Casey M Gries , Abdulelah A Alqarzaee , Yixuan Li , Vinai C Thomas , Edward Seto , Adam R Karpf , Tammy Kielian

NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma.

Cancers

Avec: Moinul Haque , Jing Li , Yung-Hsing Huang , Meaad Almowaled , Carter J Barger , Adam R Karpf , Peng Wang , Will Chen , Suzanne D Turner , Raymond Lai

Inhibition of miR-328-3p Impairs Cancer Stem Cell Function and Prevents Metastasis in Ovarian Cancer.

Cancer research

Avec: Amit K Srivastava , Ananya Banerjee , Tiantian Cui , Chunhua Han , Shurui Cai , Lu Liu , Dayong Wu , Ri Cui , Zaibo Li , Xiaoli Zhang , Guozhen Xie , Karuppaiyah Selvendiran , Srinivas Patnaik , Adam R Karpf , Jinsong Liu , David E Cohn , Qi-En Wang

Epigenetic activation of POTE genes in ovarian cancer.

Epigenetics

Avec: Ashok Sharma , Mustafa Albahrani , Wa Zhang , Christina N Kufel , Smitha R James , Kunle Odunsi , David Klinkebiel , Adam R Karpf

Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer.

Cancers

Avec: Carter J Barger , Connor Branick , Linda Chee , Adam R Karpf

RHNO1: at the crossroads of DNA replication stress, DNA repair, and cancer.

Oncogene

Avec: Niphat Jirapongwattana , Samuel F Bunting , Donald R Ronning , Gargi Ghosal , Adam R Karpf

Réseau de co-auteurs

Carter J Barger 6 collaborations

Amarnath Natarajan 4 collaborations

Mustafa Albahrani 4 collaborations

David Klinkebiel 4 collaborations

Kunle Odunsi 3 collaborations

Makenzie Vorderbruggen 2 collaborations

Sandeep Rana 2 collaborations

Smit Kour 2 collaborations

Smitha Kizhake 2 collaborations

Jixin Dong 2 collaborations

Cassie Liu 2 collaborations

Catalina Muñoz-Trujillo 2 collaborations

Olga Kim 2 collaborations

Eun Young Park 2 collaborations

David L Klinkebiel 2 collaborations

Yong-Hyun Shin 2 collaborations

Robert E Emerson 2 collaborations

Donna M Coffey 2 collaborations

Sun Young Kwon 2 collaborations

Dong-Joo Cheon 2 collaborations

Kenneth P Nephew 2 collaborations

Facundo M Fernández 2 collaborations

Chi-Heum Cho 2 collaborations

Ronny Drapkin 2 collaborations

Robert C Bast 2 collaborations

Kathy D Miller 2 collaborations

Jaeyeon Kim 2 collaborations

Wa Zhang 2 collaborations

Linda Chee 2 collaborations

Connor Branick 2 collaborations

Carlos A Velázquez-Martínez 1 collaboration

Yogesh A Sonawane 1 collaboration

Caroline M Robb 1 collaboration

Jacob I Contreras 1 collaboration

Muhammad Zahid 1 collaboration

Ling Yin 1 collaboration

Yongji Zeng 1 collaboration

Renya Zeng 1 collaboration

Yuanhong Chen 1 collaboration

Tian-Li Wang 1 collaboration

Kerry J Rodabaugh 1 collaboration

Fang Yu 1 collaboration

Xinyue Li 1 collaboration

Navneet Kaur 1 collaboration

Adrian R Black 1 collaboration

Jennifer D Black 1 collaboration

Sung Hoon Kim 1 collaboration

John A Katzenellenbogen 1 collaboration

Benita S Katzenellenbogen 1 collaboration

Joanna C Hillman 1 collaboration

Elena M Pugacheva 1 collaboration

Sirinapa Sribenja 1 collaboration

Spencer Rosario 1 collaboration

Alexander M Truskinovsky 1 collaboration

Aimee Stablewski 1 collaboration

Song Liu 1 collaboration

Dmitri I Loukinov 1 collaboration

Gabriel E Zentner 1 collaboration

Victor V Lobanenkov 1 collaboration

Michael J Higgins 1 collaboration

Svetlana D Pack 1 collaboration

Zied Abdullaev 1 collaboration

Chad J Creighton 1 collaboration

Sanghoon Kwon 1 collaboration

Edmund C Chang 1 collaboration

Theodore Chiang 1 collaboration

Alexander N Yatsenko 1 collaboration

Jeremy Chien 1 collaboration

Yang Yang-Hartwich 1 collaboration

Harikrishna Nakshatri 1 collaboration

Richard R Behringer 1 collaboration

Barbara Vanderhyden 1 collaboration

Sydney P Kubica 1 collaboration

Mudassier Ahmad 1 collaboration

Sarbjit Singh 1 collaboration

Jayapal Reddy Mallareddy 1 collaboration

Surabhi Chandra 1 collaboration

Nicholas T Woods 1 collaboration

Xinyuan Xi 1 collaboration

Fan Lei 1 collaboration

Keliang Gao 1 collaboration

Jingjing Li 1 collaboration

Rihe Liu 1 collaboration

Tatiana K Bronich 1 collaboration

Sanjit Pandey 1 collaboration

Chittibabu Guda 1 collaboration

Austin Miller 1 collaboration

Stacey N Akers 1 collaboration

Sojin Shin 1 collaboration

Francesco J DeMayo 1 collaboration

John P Lydon 1 collaboration

Shannon M Hawkins 1 collaboration

Lawrence A Quilliam 1 collaboration

Martin Widschwendter 1 collaboration

Anil K Sood 1 collaboration

Andrew K Godwin 1 collaboration

Catalina Munoz-Trujillo 1 collaboration

Lidia Boghean 1 collaboration

Lee Zou 1 collaboration

Xiangmin Lv 1 collaboration

Chunbo He 1 collaboration

Cong Huang 1 collaboration

Guohua Hua 1 collaboration

Xingcheng Chen 1 collaboration

Barbara K Timm 1 collaboration

Victoria M Maclin 1 collaboration

Abigail A Haggerty 1 collaboration

Shelly K Aust 1 collaboration

Denae M Golden 1 collaboration

Bhavana J Dave 1 collaboration

Yun-An Tseng 1 collaboration

Li Chen 1 collaboration

Hongbo Wang 1 collaboration

Peichao Chen 1 collaboration

Ronny I Drapkin 1 collaboration

Bo R Rueda 1 collaboration

John S Davis 1 collaboration

Cheng Wang 1 collaboration

Cortney E Heim 1 collaboration

Megan E Bosch 1 collaboration

Kelsey J Yamada 1 collaboration

Amy L Aldrich 1 collaboration

Sujata S Chaudhari 1 collaboration

Casey M Gries 1 collaboration

Abdulelah A Alqarzaee 1 collaboration

Yixuan Li 1 collaboration

Vinai C Thomas 1 collaboration

Edward Seto 1 collaboration

Tammy Kielian 1 collaboration

Moinul Haque 1 collaboration

Jing Li 1 collaboration

Yung-Hsing Huang 1 collaboration

Meaad Almowaled 1 collaboration

Peng Wang 1 collaboration

Will Chen 1 collaboration

Suzanne D Turner 1 collaboration

Raymond Lai 1 collaboration

Amit K Srivastava 1 collaboration

Ananya Banerjee 1 collaboration

Tiantian Cui 1 collaboration

Chunhua Han 1 collaboration

Shurui Cai 1 collaboration

Lu Liu 1 collaboration

Dayong Wu 1 collaboration

Ri Cui 1 collaboration

Zaibo Li 1 collaboration

Xiaoli Zhang 1 collaboration

Guozhen Xie 1 collaboration

Karuppaiyah Selvendiran 1 collaboration

Srinivas Patnaik 1 collaboration

Jinsong Liu 1 collaboration

David E Cohn 1 collaboration

Qi-En Wang 1 collaboration

Ashok Sharma 1 collaboration

Christina N Kufel 1 collaboration

Smitha R James 1 collaboration

Niphat Jirapongwattana 1 collaboration

Samuel F Bunting 1 collaboration

Donald R Ronning 1 collaboration

Gargi Ghosal 1 collaboration