Alain Sarasin

Affiliations

Institut Gustave Roussy, UMR8200 CNRS, 94805 Villejuif, France.

Publications (20)

Bi-allelic TARS Mutations Are Associated with Brittle Hair Phenotype.

American journal of human genetics

Avec: Arjan F Theil , Elena Botta , Anja Raams , Desiree E C Smith , Marisa I Mendes , Giuseppina Caligiuri , Sarah Giachetti , Silvia Bione , Roberta Carriero , Giordano Liberi , Luca Zardoni , Sigrid M A Swagemakers , Gajja S Salomons , Alain Sarasin , Alan Lehmann , Peter J van der Spek , Tomoo Ogi , Jan H J Hoeijmakers , Wim Vermeulen , Donata Orioli

The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells.

Free radical biology & medicine

Avec: Natália Cestari Moreno , Camila Carrião Machado Garcia , Veridiana Munford , Clarissa Ribeiro Reily Rocha , Alessandra Luiza Pelegrini , Camila Corradi , Alain Sarasin , Carlos Frederico Martins Menck

Corrigendum: Expression of constitutive fusion of ubiquitin to PCNA restores the level of immunoglobulin A/T mutations during somatic hypermutation in the Ramos cell line.

Frontiers in immunology

Avec: Leticia K Lerner , Dorine Bonte , Morwenna Le Guillou , Mahwish Mian Mohammad , Zeinab Kasraian , Alain Sarasin , Emmanuelle Despras , Said Aoufouchi

XPD/ERCC2 mutations interfere in cellular responses to oxidative stress.

Mutagenesis

Avec: Leticia K Lerner , Natália C Moreno , Clarissa R R Rocha , Veridiana Munford , Valquíria Santos , Daniela T Soltys , Camila C M Garcia , Alain Sarasin , Carlos F M Menck

XPC deficiency increases risk of hematologic malignancies through mutator phenotype and characteristic mutational signature.

Nature communications

Avec: Andrey A Yurchenko , Ismael Padioleau , Bakhyt T Matkarimov , Jean Soulier , Alain Sarasin , Sergey Nikolaev

Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome.

Scientific reports

Avec: Alexey Epanchintsev , Marc-Alexander Rauschendorf , Federico Costanzo , Nadege Calmels , Cathy Obringer , Alain Sarasin , Frederic Coin , Vincent Laugel , Jean-Marc Egly

BRN2 is a non-canonical melanoma tumor-suppressor.

Nature communications

Avec: Michael Hamm , Pierre Sohier , Valérie Petit , Jérémy H Raymond , Véronique Delmas , Madeleine Le Coz , Franck Gesbert , Colin Kenny , Zackie Aktary , Marie Pouteaux , Florian Rambow , Alain Sarasin , Nisamanee Charoenchon , Alfonso Bellacosa , Luis Sanchez-Del-Campo , Laura Mosteo , Martin Lauss , Dies Meijer , Eirikur Steingrimsson , Göran B Jönsson , Robert A Cornell , Irwin Davidson , Colin R Goding , Lionel Larue

Epigenomic signature of accelerated ageing in progeroid Cockayne syndrome.

Aging cell

Avec: Clément Crochemore , Claudia Chica , Paolo Garagnani , Giovanna Lattanzi , Steve Horvath , Alain Sarasin , Claudio Franceschi , Maria Giulia Bacalini , Miria Ricchetti

The Iberian legacy into a young genetic xeroderma pigmentosum cluster in central Brazil.

Mutation research. Genetic toxicology and environmental mutagenesis

Avec: L P Castro , M Sahbatou , F S G Kehdy , A A Farias , A A Yurchenko , T A de Souza , R C A Rosa , C T Mendes-Junior , V Borda , V Munford , É A Zanardo , S N Chehimi , L D Kulikowski , M M Aquino , T P Leal , E Tarazona-Santos , S C Chaibub , B Gener , N Calmels , V Laugel , A Sarasin , C F M Menck

Increased risk of internal tumors in DNA repair-deficient xeroderma pigmentosum patients: analysis of four international cohorts.

Orphanet journal of rare diseases

Avec: Sergey Nikolaev , Andrey A Yurchenko , Alain Sarasin

Genomic mutation landscape of skin cancers from DNA repair-deficient xeroderma pigmentosum patients.

Nature communications

Avec: Andrey A Yurchenko , Fatemeh Rajabi , Tirzah Braz-Petta , Hiva Fassihi , Alan Lehmann , Chikako Nishigori , Jinxin Wang , Ismael Padioleau , Konstantin Gunbin , Leonardo Panunzi , Fanny Morice-Picard , Pierre Laplante , Caroline Robert , Patricia L Kannouche , Carlos F M Menck , Alain Sarasin , Sergey I Nikolaev

The French Cohort of DNA Repair-Deficient Xeroderma Pigmentosum Patients: Risk of Hematological Malignancies.

Cancers

Avec: Alain Sarasin

Early-onset gynecological tumors in DNA repair-deficient xeroderma pigmentosum group C patients: a case series.

Communications medicine

Avec: Andrey A Yurchenko , Brice Fresneau , Bruno Borghese , Fatemeh Rajabi , Zora Tata , Catherine Genestie , Alain Sarasin , Sergey I Nikolaev

Mutational signatures and increased retrotransposon insertions in xeroderma pigmentosum variant skin tumors.

Carcinogenesis

Avec: Camila Corradi , Juliana B Vilar , Vanessa C Buzatto , Tiago A de Souza , Ligia P Castro , Veridiana Munford , Rodrigo De Vecchi , Pedro A F Galante , Fernanda Orpinelli , Thiago L A Miller , José L Buzzo , Mirian N Sotto , Paulo Saldiva , Jocelânio W de Oliveira , Sulamita C W Chaibub , Alain Sarasin , Carlos F M Menck

How history and geography may explain the distribution in the Comorian archipelago of a novel mutation in DNA repair-deficient xeroderma pigmentosum patients.

Genetics and molecular biology

Avec: Alain Sarasin , Patrick Munier , François Cartault

NK Cell and Fibroblast-Mediated Regulation of Skin Squamous Cell Carcinoma Invasion by CLEC2A Is Compromised in Xeroderma Pigmentosum.

The Journal of investigative dermatology

Avec: Maria Gonçalves-Maia , Yannick Gache , Miguel Basante , Estelle Cosson , Emie Salavagione , Margot Muller , Françoise Bernerd , Marie Françoise Avril , Sébastien Schaub , Alain Sarasin , Véronique M Braud , Thierry Magnaldo

Large deletions in immunoglobulin genes are associated with a sustained absence of DNA Polymerase η.

Scientific reports

Avec: Leticia K Lerner , Thuy V Nguyen , Ligia P Castro , Juliana B Vilar , Veridiana Munford , Morwenna Le Guillou , Mahwish Mian Mohammad , Véronique Vergé , Filippo Rosselli , Carlos F M Menck , Alain Sarasin , Said Aoufouchi

Psychological correlates of adherence to photoprotection in a rare disease: International survey of people with Xeroderma Pigmentosum.

British journal of health psychology

Avec: Jessica Walburn , Martha Canfield , Sam Norton , Kirby Sainsbury , Vera Araújo-Soares , Lesley Foster , Mark Berneburg , Alain Sarasin , Natalie Morrison-Bowen , Falko F Sniehotta , Robert Sarkany , John Weinman

Expression of Constitutive Fusion of Ubiquitin to PCNA Restores the Level of Immunoglobulin A/T Mutations During Somatic Hypermutation in the Ramos Cell Line.

Frontiers in immunology

Avec: Leticia K Lerner , Dorine Bonte , Morwenna Le Guillou , Mahwish Mian Mohammad , Zeinab Kasraian , Alain Sarasin , Emmanuelle Despras , Said Aoufouchi

XPC and POLH/XPV Genes Mutated in a Genetic Cluster of Xeroderma Pigmentosum Patients in Northeast Brazil.

Frontiers in genetics

Avec: Ligia Pereira Castro , Danilo Batista-Vieira , Tiago Antonio de Souza , Ana Rafaela de Souza Timoteo , Jessica Dayanna Landivar Coutinho , Isabel Cristina Pinheiro de Almeida , Sheila Ramos de Miranda Henriques , Fabio Medeiros de Azevedo , Reginaldo Cruz Alves Rosa , Patricia L Kannouche , Alain Sarasin , Carlos Frederico Martins Menck , Tirzah Braz Petta

Réseau de co-auteurs

Veridiana Munford 4 collaborations

Leticia K Lerner 4 collaborations

Carlos F M Menck 4 collaborations

Andrey A Yurchenko 4 collaborations

Morwenna Le Guillou 3 collaborations

Mahwish Mian Mohammad 3 collaborations

Said Aoufouchi 3 collaborations

Alan Lehmann 2 collaborations

Camila Corradi 2 collaborations

Carlos Frederico Martins Menck 2 collaborations

Dorine Bonte 2 collaborations

Zeinab Kasraian 2 collaborations

Emmanuelle Despras 2 collaborations

Ismael Padioleau 2 collaborations

Sergey Nikolaev 2 collaborations

Fatemeh Rajabi 2 collaborations

Patricia L Kannouche 2 collaborations

Sergey I Nikolaev 2 collaborations

Juliana B Vilar 2 collaborations

Ligia P Castro 2 collaborations

Arjan F Theil 1 collaboration

Elena Botta 1 collaboration

Anja Raams 1 collaboration

Desiree E C Smith 1 collaboration

Marisa I Mendes 1 collaboration

Giuseppina Caligiuri 1 collaboration

Sarah Giachetti 1 collaboration

Silvia Bione 1 collaboration

Roberta Carriero 1 collaboration

Giordano Liberi 1 collaboration

Luca Zardoni 1 collaboration

Sigrid M A Swagemakers 1 collaboration

Gajja S Salomons 1 collaboration

Peter J van der Spek 1 collaboration

Tomoo Ogi 1 collaboration

Jan H J Hoeijmakers 1 collaboration

Wim Vermeulen 1 collaboration

Donata Orioli 1 collaboration

Natália Cestari Moreno 1 collaboration

Camila Carrião Machado Garcia 1 collaboration

Clarissa Ribeiro Reily Rocha 1 collaboration

Alessandra Luiza Pelegrini 1 collaboration

Natália C Moreno 1 collaboration

Clarissa R R Rocha 1 collaboration

Valquíria Santos 1 collaboration

Daniela T Soltys 1 collaboration

Camila C M Garcia 1 collaboration

Bakhyt T Matkarimov 1 collaboration

Jean Soulier 1 collaboration

Alexey Epanchintsev 1 collaboration

Marc-Alexander Rauschendorf 1 collaboration

Federico Costanzo 1 collaboration

Nadege Calmels 1 collaboration

Cathy Obringer 1 collaboration

Frederic Coin 1 collaboration

Vincent Laugel 1 collaboration

Jean-Marc Egly 1 collaboration

Michael Hamm 1 collaboration

Pierre Sohier 1 collaboration

Valérie Petit 1 collaboration

Jérémy H Raymond 1 collaboration

Véronique Delmas 1 collaboration

Madeleine Le Coz 1 collaboration

Franck Gesbert 1 collaboration

Colin Kenny 1 collaboration

Zackie Aktary 1 collaboration

Marie Pouteaux 1 collaboration

Florian Rambow 1 collaboration

Nisamanee Charoenchon 1 collaboration

Alfonso Bellacosa 1 collaboration

Luis Sanchez-Del-Campo 1 collaboration

Laura Mosteo 1 collaboration

Martin Lauss 1 collaboration

Dies Meijer 1 collaboration

Eirikur Steingrimsson 1 collaboration

Göran B Jönsson 1 collaboration

Robert A Cornell 1 collaboration

Irwin Davidson 1 collaboration

Colin R Goding 1 collaboration

Lionel Larue 1 collaboration

Clément Crochemore 1 collaboration

Claudia Chica 1 collaboration

Paolo Garagnani 1 collaboration

Giovanna Lattanzi 1 collaboration

Steve Horvath 1 collaboration

Claudio Franceschi 1 collaboration

Maria Giulia Bacalini 1 collaboration

Miria Ricchetti 1 collaboration

L P Castro 1 collaboration

M Sahbatou 1 collaboration

F S G Kehdy 1 collaboration

A A Farias 1 collaboration

A A Yurchenko 1 collaboration

T A de Souza 1 collaboration

R C A Rosa 1 collaboration

C T Mendes-Junior 1 collaboration

V Borda 1 collaboration

V Munford 1 collaboration

É A Zanardo 1 collaboration

S N Chehimi 1 collaboration

L D Kulikowski 1 collaboration

M M Aquino 1 collaboration

T P Leal 1 collaboration

E Tarazona-Santos 1 collaboration

S C Chaibub 1 collaboration

B Gener 1 collaboration

N Calmels 1 collaboration

V Laugel 1 collaboration

A Sarasin 1 collaboration

C F M Menck 1 collaboration

Tirzah Braz-Petta 1 collaboration

Hiva Fassihi 1 collaboration

Chikako Nishigori 1 collaboration

Jinxin Wang 1 collaboration

Konstantin Gunbin 1 collaboration

Leonardo Panunzi 1 collaboration

Fanny Morice-Picard 1 collaboration

Pierre Laplante 1 collaboration

Caroline Robert 1 collaboration

Brice Fresneau 1 collaboration

Bruno Borghese 1 collaboration

Zora Tata 1 collaboration

Catherine Genestie 1 collaboration

Vanessa C Buzatto 1 collaboration

Tiago A de Souza 1 collaboration

Rodrigo De Vecchi 1 collaboration

Pedro A F Galante 1 collaboration

Fernanda Orpinelli 1 collaboration

Thiago L A Miller 1 collaboration

José L Buzzo 1 collaboration

Mirian N Sotto 1 collaboration

Paulo Saldiva 1 collaboration

Jocelânio W de Oliveira 1 collaboration

Sulamita C W Chaibub 1 collaboration

Patrick Munier 1 collaboration

François Cartault 1 collaboration

Maria Gonçalves-Maia 1 collaboration

Yannick Gache 1 collaboration

Miguel Basante 1 collaboration

Estelle Cosson 1 collaboration

Emie Salavagione 1 collaboration

Margot Muller 1 collaboration

Françoise Bernerd 1 collaboration

Marie Françoise Avril 1 collaboration

Sébastien Schaub 1 collaboration

Véronique M Braud 1 collaboration

Thierry Magnaldo 1 collaboration

Thuy V Nguyen 1 collaboration

Véronique Vergé 1 collaboration

Filippo Rosselli 1 collaboration

Jessica Walburn 1 collaboration

Martha Canfield 1 collaboration

Sam Norton 1 collaboration

Kirby Sainsbury 1 collaboration

Vera Araújo-Soares 1 collaboration

Lesley Foster 1 collaboration

Mark Berneburg 1 collaboration

Natalie Morrison-Bowen 1 collaboration

Falko F Sniehotta 1 collaboration

Robert Sarkany 1 collaboration

John Weinman 1 collaboration

Ligia Pereira Castro 1 collaboration

Danilo Batista-Vieira 1 collaboration

Tiago Antonio de Souza 1 collaboration

Ana Rafaela de Souza Timoteo 1 collaboration

Jessica Dayanna Landivar Coutinho 1 collaboration

Isabel Cristina Pinheiro de Almeida 1 collaboration

Sheila Ramos de Miranda Henriques 1 collaboration

Fabio Medeiros de Azevedo 1 collaboration

Reginaldo Cruz Alves Rosa 1 collaboration

Tirzah Braz Petta 1 collaboration