Alessandro Carugo

Affiliations

Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Publications (14)

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation.

Cell reports

Avec: Yuting Sun , Madhavi Bandi , Timothy Lofton , Melinda Smith , Christopher A Bristow , Alessandro Carugo , Norma Rogers , Paul Leonard , Qing Chang , Robert Mullinax , Jing Han , Xi Shi , Sahil Seth , Brooke A Meyers , Meredith Miller , Lili Miao , Xiaoyan Ma , Ningping Feng , Virginia Giuliani , Mary Geck Do , Barbara Czako , Wylie S Palmer , Faika Mseeh , John M Asara , Yongying Jiang , Pietro Morlacchi , Shuping Zhao , Michael Peoples , Trang N Tieu , Marc O Warmoes , Philip L Lorenzi , Florian L Muller , Ronald A DePinho , Giulio F Draetta , Carlo Toniatti , Philip Jones , Timothy P Heffernan , Joseph R Marszalek

Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations.

Oncogene

Avec: Maryam Shariati , Kurt W Evans , Xiaofeng Zheng , Christopher A Bristow , Patrick Kwok-Shing Ng , Yasmeen Q Rizvi , Coya Tapia , Fei Yang , Alessandro Carugo , Timothy P Heffernan , Michael D Peoples , Debu Tripathy , Funda Meric-Bernstam

Epithelial memory of inflammation limits tissue damage while promoting pancreatic tumorigenesis.

Science (New York, N.Y.)

Avec: Edoardo Del Poggetto , I-Lin Ho , Chiara Balestrieri , Er-Yen Yen , Shaojun Zhang , Francesca Citron , Rutvi Shah , Denise Corti , Giuseppe R Diaferia , Chieh-Yuan Li , Sara Loponte , Federica Carbone , Yoku Hayakawa , Giovanni Valenti , Shan Jiang , Luigi Sapio , Hong Jiang , Prasenjit Dey , Sisi Gao , Angela K Deem , Stefan Rose-John , Wantong Yao , Haoqiang Ying , Andrew D Rhim , Giannicola Genovese , Timothy P Heffernan , Anirban Maitra , Timothy C Wang , Linghua Wang , Giulio F Draetta , Alessandro Carugo , Gioacchino Natoli , Andrea Viale

Evolutionary fingerprints of EMT in pancreatic cancers.

bioRxiv : the preprint server for biology

Avec: Luigi Perelli , Li Zhang , Sarah Mangiameli , Andrew J C Russell , Francesca Giannese , Fuduan Peng , Federica Carbone , Courtney Le , Hania Khan , Francesca Citron , Melinda Soeung , Truong Nguyen Anh Lam , Sebastian Lundgren , Cihui Zhu , Desiree Catania , Ningping Feng , Enrico Gurreri , Alessandro Sgambato , Giampaolo Tortora , Giulio F Draetta , Giovanni Tonon , Andrew Futreal , Virginia Giuliani , Alessandro Carugo , Andrea Viale , Timothy P Heffernan , Linghua Wang , Davide Cittaro , Fei Chen , Giannicola Genovese

WRAD core perturbation impairs DNA replication fidelity promoting immunoediting in pancreatic cancer.

bioRxiv : the preprint server for biology

Avec: Francesca Citron , I-Lin Ho , Chiara Balestrieri , Zhaoliang Liu , Er-Yen Yen , Luca Cecchetto , Luigi Perelli , Li Zhang , Luis Castillo Montanez , Nicholas Blazanin , Charles A Dyke , Rutvi Shah , Sergio Attanasio , Sanjana Srinivasan , Ko-Chien Chen , Ziheng Chen , Iolanda Scognamiglio , Nhung Pham , Hania Khan , Shan Jiang , Jing Pan , Ben Vanderkruk , Cecilia S Leung , Mahinur Mattohti , Kunal Rai , Yanshuo Chu , Linghua Wang , Sisi Gao , Angela K Deem , Alessandro Carugo , Huamin Wang , Wantong Yao , Giovanni Tonon , Yun Xiong , Philip L Lorenzi , Chiara Bonini , M Anna Zal , Brad G Hoffman , Tim Heffernan , Virginia Giuliani , Collene R Jeter , Yonathan Lissanu , Giannicola Genovese , Mauro Di Pilato , Andrea Viale , Giulio F Draetta

Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma.

Cancer cell

Avec: Pavlos Msaouel , Gabriel G Malouf , Xiaoping Su , Hui Yao , Durga N Tripathi , Melinda Soeung , Jianjun Gao , Priya Rao , Cristian Coarfa , Chad J Creighton , Jean-Philippe Bertocchio , Selvi Kunnimalaiyaan , Asha S Multani , Jorge Blando , Rong He , Daniel D Shapiro , Luigi Perelli , Sanjana Srinivasan , Federica Carbone , Patrick G Pilié , Menuka Karki , Riyad N H Seervai , Bujamin H Vokshi , Dolores Lopez-Terrada , Emily H Cheng , Ximing Tang , Wei Lu , Ignacio I Wistuba , Timothy C Thompson , Irwin Davidson , Virginia Giuliani , Katharina Schlacher , Alessandro Carugo , Timothy P Heffernan , Padmanee Sharma , Jose A Karam , Christopher G Wood , Cheryl L Walker , Giannicola Genovese , Nizar M Tannir

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.

Cancer research

Avec: Carla Mottini , Hideo Tomihara , Diego Carrella , Alessia Lamolinara , Manuela Iezzi , Justin K Huang , Carla A Amoreo , Simonetta Buglioni , Isabella Manni , Frederick S Robinson , Rosalba Minelli , Ya'an Kang , Jason B Fleming , Michael P Kim , Christopher A Bristow , Daniela Trisciuoglio , Antonella Iuliano , Donatella Del Bufalo , Diego Di Bernardo , Davide Melisi , Giulio F Draetta , Gennaro Ciliberto , Alessandro Carugo , Luca Cardone

Current and Future Horizons of Patient-Derived Xenograft Models in Colorectal Cancer Translational Research.

Cancers

Avec: Akira Inoue , Angela K Deem , Scott Kopetz , Timothy P Heffernan , Giulio F Draetta , Alessandro Carugo

ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer.

Nature communications

Avec: Roxsan Manshouri , Etienne Coyaud , Samrat T Kundu , David H Peng , Sabrina A Stratton , Kendra Alton , Rakhee Bajaj , Jared J Fradette , Rosalba Minelli , Michael D Peoples , Alessandro Carugo , Fengju Chen , Christopher Bristow , Jeffrey J Kovacs , Michelle C Barton , Tim Heffernan , Chad J Creighton , Brian Raught , Don L Gibbons

ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.

Science translational medicine

Avec: David H Peng , Samrat T Kundu , Jared J Fradette , Lixia Diao , Pan Tong , Lauren A Byers , Jing Wang , Jaime Rodriguez Canales , Pamela A Villalobos , Barbara Mino , Yanan Yang , Rosalba Minelli , Michael D Peoples , Christopher A Bristow , Timothy P Heffernan , Alessandro Carugo , Ignacio I Wistuba , Don L Gibbons

Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.

Cancers

Avec: Jessica M Konen , B Leticia Rodriguez , Jared J Fradette , Laura Gibson , Denali Davis , Rosalba Minelli , Michael D Peoples , Jeffrey Kovacs , Alessandro Carugo , Christopher Bristow , Timothy Heffernan , Don L Gibbons

Association of High-Intensity Exercise with Renal Medullary Carcinoma in Individuals with Sickle Cell Trait: Clinical Observations and Experimental Animal Studies.

Cancers

Avec: Daniel D Shapiro , Melinda Soeung , Luigi Perelli , Eleonora Dondossola , Devaki Shilpa Surasi , Durga N Tripathi , Jean-Philippe Bertocchio , Federica Carbone , Michael W Starbuck , Michael L Van Alstine , Priya Rao , Matthew H G Katz , Nathan H Parker , Amishi Y Shah , Alessandro Carugo , Timothy P Heffernan , Keri L Schadler , Christopher Logothetis , Cheryl L Walker , Christopher G Wood , Jose A Karam , Giulio F Draetta , Nizar M Tannir , Giannicola Genovese , Pavlos Msaouel

PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.

Nature communications

Avec: Virginia Giuliani , Meredith A Miller , Chiu-Yi Liu , Stella R Hartono , Caleb A Class , Christopher A Bristow , Erika Suzuki , Lionel A Sanz , Guang Gao , Jason P Gay , Ningping Feng , Johnathon L Rose , Hideo Tomihara , Joseph R Daniele , Michael D Peoples , Jennifer P Bardenhagen , Mary K Geck Do , Qing E Chang , Bhavatarini Vangamudi , Christopher Vellano , Haoqiang Ying , Angela K Deem , Kim-Anh Do , Giannicola Genovese , Joseph R Marszalek , Jeffrey J Kovacs , Michael Kim , Jason B Fleming , Ernesto Guccione , Andrea Viale , Anirban Maitra , M Emilia Di Francesco , Timothy A Yap , Philip Jones , Giulio Draetta , Alessandro Carugo , Frederic Chedin , Timothy P Heffernan

BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening.

American journal of cancer research

Avec: Jie Ding , Shaofang Wu , Chen Zhang , Arnav Garyali , Emmanuel Martinez-Ledesma , Feng Gao , Adarsha Pokkulandra , Xiaolong Li , Christopher Bristow , Alessandro Carugo , Dimpy Koul , Wk Alfred Yung

Réseau de co-auteurs

Timothy P Heffernan 9 collaborations

Giulio F Draetta 7 collaborations

Giannicola Genovese 6 collaborations

Christopher A Bristow 5 collaborations

Virginia Giuliani 5 collaborations

Michael D Peoples 5 collaborations

Federica Carbone 4 collaborations

Angela K Deem 4 collaborations

Andrea Viale 4 collaborations

Luigi Perelli 4 collaborations

Rosalba Minelli 4 collaborations

Ningping Feng 3 collaborations

Francesca Citron 3 collaborations

Linghua Wang 3 collaborations

Melinda Soeung 3 collaborations

Jared J Fradette 3 collaborations

Christopher Bristow 3 collaborations

Don L Gibbons 3 collaborations

Philip L Lorenzi 2 collaborations

Philip Jones 2 collaborations

Joseph R Marszalek 2 collaborations

I-Lin Ho 2 collaborations

Chiara Balestrieri 2 collaborations

Er-Yen Yen 2 collaborations

Rutvi Shah 2 collaborations

Shan Jiang 2 collaborations

Sisi Gao 2 collaborations

Wantong Yao 2 collaborations

Haoqiang Ying 2 collaborations

Anirban Maitra 2 collaborations

Li Zhang 2 collaborations

Hania Khan 2 collaborations

Giovanni Tonon 2 collaborations

Sanjana Srinivasan 2 collaborations

Tim Heffernan 2 collaborations

Pavlos Msaouel 2 collaborations

Durga N Tripathi 2 collaborations

Priya Rao 2 collaborations

Chad J Creighton 2 collaborations

Jean-Philippe Bertocchio 2 collaborations

Daniel D Shapiro 2 collaborations

Ignacio I Wistuba 2 collaborations

Jose A Karam 2 collaborations

Christopher G Wood 2 collaborations

Cheryl L Walker 2 collaborations

Nizar M Tannir 2 collaborations

Hideo Tomihara 2 collaborations

Jason B Fleming 2 collaborations

Samrat T Kundu 2 collaborations

David H Peng 2 collaborations

Jeffrey J Kovacs 2 collaborations

Yuting Sun 1 collaboration

Madhavi Bandi 1 collaboration

Timothy Lofton 1 collaboration

Melinda Smith 1 collaboration

Norma Rogers 1 collaboration

Paul Leonard 1 collaboration

Qing Chang 1 collaboration

Robert Mullinax 1 collaboration

Jing Han 1 collaboration

Xi Shi 1 collaboration

Sahil Seth 1 collaboration

Brooke A Meyers 1 collaboration

Meredith Miller 1 collaboration

Lili Miao 1 collaboration

Xiaoyan Ma 1 collaboration

Mary Geck Do 1 collaboration

Barbara Czako 1 collaboration

Wylie S Palmer 1 collaboration

Faika Mseeh 1 collaboration

John M Asara 1 collaboration

Yongying Jiang 1 collaboration

Pietro Morlacchi 1 collaboration

Shuping Zhao 1 collaboration

Michael Peoples 1 collaboration

Trang N Tieu 1 collaboration

Marc O Warmoes 1 collaboration

Florian L Muller 1 collaboration

Ronald A DePinho 1 collaboration

Carlo Toniatti 1 collaboration

Maryam Shariati 1 collaboration

Kurt W Evans 1 collaboration

Xiaofeng Zheng 1 collaboration

Patrick Kwok-Shing Ng 1 collaboration

Yasmeen Q Rizvi 1 collaboration

Coya Tapia 1 collaboration

Fei Yang 1 collaboration

Debu Tripathy 1 collaboration

Funda Meric-Bernstam 1 collaboration

Edoardo Del Poggetto 1 collaboration

Shaojun Zhang 1 collaboration

Denise Corti 1 collaboration

Giuseppe R Diaferia 1 collaboration

Chieh-Yuan Li 1 collaboration

Sara Loponte 1 collaboration

Yoku Hayakawa 1 collaboration

Giovanni Valenti 1 collaboration

Luigi Sapio 1 collaboration

Hong Jiang 1 collaboration

Prasenjit Dey 1 collaboration

Stefan Rose-John 1 collaboration

Andrew D Rhim 1 collaboration

Timothy C Wang 1 collaboration

Gioacchino Natoli 1 collaboration

Sarah Mangiameli 1 collaboration

Andrew J C Russell 1 collaboration

Francesca Giannese 1 collaboration

Fuduan Peng 1 collaboration

Courtney Le 1 collaboration

Truong Nguyen Anh Lam 1 collaboration

Sebastian Lundgren 1 collaboration

Cihui Zhu 1 collaboration

Desiree Catania 1 collaboration

Enrico Gurreri 1 collaboration

Alessandro Sgambato 1 collaboration

Giampaolo Tortora 1 collaboration

Andrew Futreal 1 collaboration

Davide Cittaro 1 collaboration

Fei Chen 1 collaboration

Zhaoliang Liu 1 collaboration

Luca Cecchetto 1 collaboration

Luis Castillo Montanez 1 collaboration

Nicholas Blazanin 1 collaboration

Charles A Dyke 1 collaboration

Sergio Attanasio 1 collaboration

Ko-Chien Chen 1 collaboration

Ziheng Chen 1 collaboration

Iolanda Scognamiglio 1 collaboration

Nhung Pham 1 collaboration

Jing Pan 1 collaboration

Ben Vanderkruk 1 collaboration

Cecilia S Leung 1 collaboration

Mahinur Mattohti 1 collaboration

Kunal Rai 1 collaboration

Yanshuo Chu 1 collaboration

Huamin Wang 1 collaboration

Yun Xiong 1 collaboration

Chiara Bonini 1 collaboration

M Anna Zal 1 collaboration

Brad G Hoffman 1 collaboration

Collene R Jeter 1 collaboration

Yonathan Lissanu 1 collaboration

Mauro Di Pilato 1 collaboration

Gabriel G Malouf 1 collaboration

Xiaoping Su 1 collaboration

Hui Yao 1 collaboration

Jianjun Gao 1 collaboration

Cristian Coarfa 1 collaboration

Selvi Kunnimalaiyaan 1 collaboration

Asha S Multani 1 collaboration

Jorge Blando 1 collaboration

Rong He 1 collaboration

Patrick G Pilié 1 collaboration

Menuka Karki 1 collaboration

Riyad N H Seervai 1 collaboration

Bujamin H Vokshi 1 collaboration

Dolores Lopez-Terrada 1 collaboration

Emily H Cheng 1 collaboration

Ximing Tang 1 collaboration

Wei Lu 1 collaboration

Timothy C Thompson 1 collaboration

Irwin Davidson 1 collaboration

Katharina Schlacher 1 collaboration

Padmanee Sharma 1 collaboration

Carla Mottini 1 collaboration

Diego Carrella 1 collaboration

Alessia Lamolinara 1 collaboration

Manuela Iezzi 1 collaboration

Justin K Huang 1 collaboration

Carla A Amoreo 1 collaboration

Simonetta Buglioni 1 collaboration

Isabella Manni 1 collaboration

Frederick S Robinson 1 collaboration

Ya'an Kang 1 collaboration

Michael P Kim 1 collaboration

Daniela Trisciuoglio 1 collaboration

Antonella Iuliano 1 collaboration

Donatella Del Bufalo 1 collaboration

Diego Di Bernardo 1 collaboration

Davide Melisi 1 collaboration

Gennaro Ciliberto 1 collaboration

Luca Cardone 1 collaboration

Akira Inoue 1 collaboration

Scott Kopetz 1 collaboration

Roxsan Manshouri 1 collaboration

Etienne Coyaud 1 collaboration

Sabrina A Stratton 1 collaboration

Kendra Alton 1 collaboration

Rakhee Bajaj 1 collaboration

Fengju Chen 1 collaboration

Michelle C Barton 1 collaboration

Brian Raught 1 collaboration

Lixia Diao 1 collaboration

Pan Tong 1 collaboration

Lauren A Byers 1 collaboration

Jing Wang 1 collaboration

Jaime Rodriguez Canales 1 collaboration

Pamela A Villalobos 1 collaboration

Barbara Mino 1 collaboration

Yanan Yang 1 collaboration

Jessica M Konen 1 collaboration

B Leticia Rodriguez 1 collaboration

Laura Gibson 1 collaboration

Denali Davis 1 collaboration

Jeffrey Kovacs 1 collaboration

Timothy Heffernan 1 collaboration

Eleonora Dondossola 1 collaboration

Devaki Shilpa Surasi 1 collaboration

Michael W Starbuck 1 collaboration

Michael L Van Alstine 1 collaboration

Matthew H G Katz 1 collaboration

Nathan H Parker 1 collaboration

Amishi Y Shah 1 collaboration

Keri L Schadler 1 collaboration

Christopher Logothetis 1 collaboration

Meredith A Miller 1 collaboration

Chiu-Yi Liu 1 collaboration

Stella R Hartono 1 collaboration

Caleb A Class 1 collaboration

Erika Suzuki 1 collaboration

Lionel A Sanz 1 collaboration

Guang Gao 1 collaboration

Jason P Gay 1 collaboration

Johnathon L Rose 1 collaboration

Joseph R Daniele 1 collaboration

Jennifer P Bardenhagen 1 collaboration

Mary K Geck Do 1 collaboration

Qing E Chang 1 collaboration

Bhavatarini Vangamudi 1 collaboration

Christopher Vellano 1 collaboration

Kim-Anh Do 1 collaboration

Michael Kim 1 collaboration

Ernesto Guccione 1 collaboration

M Emilia Di Francesco 1 collaboration

Timothy A Yap 1 collaboration

Giulio Draetta 1 collaboration

Frederic Chedin 1 collaboration

Jie Ding 1 collaboration

Shaofang Wu 1 collaboration

Chen Zhang 1 collaboration

Arnav Garyali 1 collaboration

Emmanuel Martinez-Ledesma 1 collaboration

Feng Gao 1 collaboration

Adarsha Pokkulandra 1 collaboration

Xiaolong Li 1 collaboration

Dimpy Koul 1 collaboration

Wk Alfred Yung 1 collaboration