Alexandra Leary

Affiliations

Institut Gustave Roussy, Villejuif, France.

ORCID: 0000-0002-2043-2244

Publications (16)

CA-125 ELIMination Rate Constant K (KELIM) Is a Marker of Chemosensitivity in Patients with Ovarian Cancer: Results from the Phase II CHIVA Trial.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Benoit You , Patrick Robelin , Michel Tod , Christophe Louvet , Jean-Pierre Lotz , Sophie Abadie-Lacourtoisie , Michel Fabbro , Christophe Desauw , Nathalie Bonichon-Lamichhane , Jean-Emmanuel Kurtz , Philippe Follana , Marianne Leheurteur , Francesco Del Piano , Gwénael Ferron , Gaëtan De Rauglaudre , Isabelle Ray-Coquard , Pierre Combe , Annick Chevalier-Place , Florence Joly , Alexandra Leary , Eric Pujade-Lauraine , Gilles Freyer , Olivier Colomban

Neoadjuvant chemotherapy alters the balance of effector to suppressor immune cells in advanced ovarian cancer.

Cancer immunology, immunotherapy : CII

Avec: Alexandra Leary , Catherine Genestie , Félix Blanc-Durand , Sébastien Gouy , Ariane Dunant , Amandine Maulard , Françoise Drusch , Bianca Cheaib , Judith Michels , Enrica Bentivegna , Audrey LeFormal , Soizick Mesnage , Philippe Morice , Patricia Pautier , Aya S Khairallah

An observational study on the rate of reporting of adverse event on healthcare staff in a mental health setting: An application of Poisson expectation maximisation analysis on nurse staffing data.

Health informatics journal

Avec: Robert M Cook , Sarahjane Jones , Gemma C Williams , Daniel Worsley , Ray Walker , Mark Radford , Alison Leary

Phase I dose-escalation study of F14512, a polyamine-vectorized topoisomerase II inhibitor, in patients with platinum-refractory or resistant ovarian cancer.

Investigational new drugs

Avec: Alexandra Leary , Christophe Le Tourneau , Andrea Varga , Marie-Paule Sablin , Carlos Gomez-Roca , Nicolas Guilbaud , Aurelie Petain , Mariya Pavlyuk , Jean-Pierre Delord

Estradiol promotes cell survival and induces Greb1 expression in granulosa cell tumors of the ovary through an ERα-dependent mechanism.

The Journal of pathology

Avec: Victoria Cluzet , Marie M Devillers , Florence Petit , Alice Pierre , Frank Giton , Eloïse Airaud , David L'Hôte , Alexandra Leary , Catherine Genestie , Isabelle Treilleux , Anne Mayeur , John A Katzenellenbogen , Sung Hoon Kim , Joëlle Cohen-Tannoudji , Stéphanie Chauvin , Céline J Guigon

Concordance of BRCA mutation detection in tumor versus blood, and frequency of bi-allelic loss of BRCA in tumors from patients in the phase III SOLO2 trial.

Gynecologic oncology

Avec: Darren R Hodgson , Jessica S Brown , Simon P Dearden , Zhongwu Lai , Cathy E Elks , Tsveta Milenkova , Brian A Dougherty , Jerry S Lanchbury , Michael Perry , Kirsten M Timms , Elizabeth A Harrington , J Carl Barrett , Alexandra Leary , Eric Pujade-Lauraine

Characterization of patients with long-term responses to rucaparib treatment in recurrent ovarian cancer.

Gynecologic oncology

Avec: Elizabeth M Swisher , Rebecca S Kristeleit , Amit M Oza , Anna V Tinker , Isabelle Ray-Coquard , Ana Oaknin , Robert L Coleman , Howard A Burris , Carol Aghajanian , David M O'Malley , Alexandra Leary , Stephen Welch , Diane Provencher , Geoffrey I Shapiro , Lee-May Chen , Ronnie Shapira-Frommer , Scott H Kaufmann , Sandra Goble , Lara Maloney , Tanya Kwan , Kevin K Lin , Iain A McNeish

ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: R E Miller , A Leary , C L Scott , V Serra , C J Lord , D Bowtell , D K Chang , D W Garsed , J Jonkers , J A Ledermann , S Nik-Zainal , I Ray-Coquard , S P Shah , X Matias-Guiu , E M Swisher , L R Yates

Evaluation of adjuvant vaginal vault brachytherapy in early stage cervical cancer patients.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

Avec: E Bronsart , C Petit , S Gouy , S Bockel , S Espenel , T Kumar , I Fumagalli , A Maulard , R El Ayachy , C Genestie , A Leary , P Pautier , P Morice , C Haie-Meder , C Chargari

Long-Term Toxicity and Health-Related Quality of Life After Adjuvant Chemoradiation Therapy or Radiation Therapy Alone for High-Risk Endometrial Cancer in the Randomized PORTEC-3 Trial.

International journal of radiation oncology, biology, physics

Avec: Cathalijne C B Post , Stephanie M de Boer , Melanie E Powell , Linda Mileshkin , Dionyssios Katsaros , Paul Bessette , Christine Haie-Meder , Nelleke P B Ottevanger , Jonathan A Ledermann , Pearly Khaw , Romerai D'Amico , Anthony Fyles , Marie Hélène Baron , Henry C Kitchener , Hans W Nijman , Ludy C H W Lutgens , Susan Brooks , Ina M Jürgenliemk-Schulz , Amanda Feeney , Geraldine Goss , Roldano Fossati , Prafull Ghatage , Alexandra Leary , Viet Do , Andrea A Lissoni , Mary McCormack , Remi A Nout , Karen W Verhoeven-Adema , Vincent T H B M Smit , Hein Putter , Carien L Creutzberg

Modeling the Multiple Sclerosis Specialist Nurse Workforce by Determination of Optimum Caseloads in the United Kingdom.

International journal of MS care

Avec: Geoffrey Punshon , Jo Sopala , Guy Hannan , Megan Roberts , Karen Vernon , Annabella Pearce , Alison Leary

Molecular Landscape of Therapy-related Myeloid Neoplasms in Patients Previously Treated for Gynecologic and Breast Cancers.

HemaSphere

Avec: Sabine Khalife-Hachem , Khalil Saleh , Florence Pasquier , Christophe Willekens , Anthony Tarabay , Leony Antoun , Thomas Grinda , Cristina Castilla-Llorente , Matthieu Duchmann , Cyril Quivoron , Nathalie Auger , Veronique Saada , Suzette Delaloge , Alexandra Leary , Aline Renneville , Ileana Antony-Debre , Filippo Rosselli , Stéphane De Botton , Flore Salviat , Christophe Marzac , Jean-Baptiste Micol

Combined modality including novel sensitizers in gynecological cancers.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Avec: Yuedan Zhou , Sophie Espenel , Samir Achkar , Alexandra Leary , Sebastien Gouy , Cyrus Chargari

Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers.

Journal for immunotherapy of cancer

Avec: Laetitia Nebot-Bral , Antoine Hollebecque , Andrey A Yurchenko , Louise de Forceville , Mathieu Danjou , Jean-Mehdi Jouniaux , Reginaldo C A Rosa , Caroline Pouvelle , Said Aoufouchi , Perrine Vuagnat , Cristina Smolenschi , Emeline Colomba , Alexandra Leary , Aurelien Marabelle , Jean-Yves Scoazec , Lydie Cassard , Sergey Nikolaev , Nathalie Chaput , Patricia Kannouche

p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Avec: Lisa Vermij , Alicia Léon-Castillo , Naveena Singh , Melanie E Powell , Richard J Edmondson , Catherine Genestie , Pearly Khaw , Jan Pyman , C Meg McLachlin , Prafull Ghatage , Stephanie M de Boer , Hans W Nijman , Vincent T H B M Smit , Emma J Crosbie , Alexandra Leary , Carien L Creutzberg , Nanda Horeweg , Tjalling Bosse , Auteur inconnu

Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Paul DiSilvestro , Susana Banerjee , Nicoletta Colombo , Giovanni Scambia , Byoung-Gie Kim , Ana Oaknin , Michael Friedlander , Alla Lisyanskaya , Anne Floquet , Alexandra Leary , Gabe S Sonke , Charlie Gourley , Amit Oza , Antonio González-Martín , Carol Aghajanian , William Bradley , Cara Mathews , Joyce Liu , John McNamara , Elizabeth S Lowe , Mei-Lin Ah-See , Kathleen N Moore , Auteur inconnu

Réseau de co-auteurs

Catherine Genestie 3 collaborations

Isabelle Ray-Coquard 2 collaborations

Eric Pujade-Lauraine 2 collaborations

Alison Leary 2 collaborations

Ana Oaknin 2 collaborations

Carol Aghajanian 2 collaborations

A Leary 2 collaborations

Stephanie M de Boer 2 collaborations

Melanie E Powell 2 collaborations

Pearly Khaw 2 collaborations

Hans W Nijman 2 collaborations

Prafull Ghatage 2 collaborations

Vincent T H B M Smit 2 collaborations

Carien L Creutzberg 2 collaborations

None None 2 collaborations

Benoit You 1 collaboration

Patrick Robelin 1 collaboration

Michel Tod 1 collaboration

Christophe Louvet 1 collaboration

Jean-Pierre Lotz 1 collaboration

Sophie Abadie-Lacourtoisie 1 collaboration

Michel Fabbro 1 collaboration

Christophe Desauw 1 collaboration

Nathalie Bonichon-Lamichhane 1 collaboration

Jean-Emmanuel Kurtz 1 collaboration

Philippe Follana 1 collaboration

Marianne Leheurteur 1 collaboration

Francesco Del Piano 1 collaboration

Gwénael Ferron 1 collaboration

Gaëtan De Rauglaudre 1 collaboration

Pierre Combe 1 collaboration

Annick Chevalier-Place 1 collaboration

Florence Joly 1 collaboration

Gilles Freyer 1 collaboration

Olivier Colomban 1 collaboration

Félix Blanc-Durand 1 collaboration

Sébastien Gouy 1 collaboration

Ariane Dunant 1 collaboration

Amandine Maulard 1 collaboration

Françoise Drusch 1 collaboration

Bianca Cheaib 1 collaboration

Judith Michels 1 collaboration

Enrica Bentivegna 1 collaboration

Audrey LeFormal 1 collaboration

Soizick Mesnage 1 collaboration

Philippe Morice 1 collaboration

Patricia Pautier 1 collaboration

Aya S Khairallah 1 collaboration

Robert M Cook 1 collaboration

Sarahjane Jones 1 collaboration

Gemma C Williams 1 collaboration

Daniel Worsley 1 collaboration

Ray Walker 1 collaboration

Mark Radford 1 collaboration

Christophe Le Tourneau 1 collaboration

Andrea Varga 1 collaboration

Marie-Paule Sablin 1 collaboration

Carlos Gomez-Roca 1 collaboration

Nicolas Guilbaud 1 collaboration

Aurelie Petain 1 collaboration

Mariya Pavlyuk 1 collaboration

Jean-Pierre Delord 1 collaboration

Victoria Cluzet 1 collaboration

Marie M Devillers 1 collaboration

Florence Petit 1 collaboration

Alice Pierre 1 collaboration

Frank Giton 1 collaboration

Eloïse Airaud 1 collaboration

David L'Hôte 1 collaboration

Isabelle Treilleux 1 collaboration

Anne Mayeur 1 collaboration

John A Katzenellenbogen 1 collaboration

Sung Hoon Kim 1 collaboration

Joëlle Cohen-Tannoudji 1 collaboration

Stéphanie Chauvin 1 collaboration

Céline J Guigon 1 collaboration

Darren R Hodgson 1 collaboration

Jessica S Brown 1 collaboration

Simon P Dearden 1 collaboration

Zhongwu Lai 1 collaboration

Cathy E Elks 1 collaboration

Tsveta Milenkova 1 collaboration

Brian A Dougherty 1 collaboration

Jerry S Lanchbury 1 collaboration

Michael Perry 1 collaboration

Kirsten M Timms 1 collaboration

Elizabeth A Harrington 1 collaboration

J Carl Barrett 1 collaboration

Elizabeth M Swisher 1 collaboration

Rebecca S Kristeleit 1 collaboration

Amit M Oza 1 collaboration

Anna V Tinker 1 collaboration

Robert L Coleman 1 collaboration

Howard A Burris 1 collaboration

David M O'Malley 1 collaboration

Stephen Welch 1 collaboration

Diane Provencher 1 collaboration

Geoffrey I Shapiro 1 collaboration

Lee-May Chen 1 collaboration

Ronnie Shapira-Frommer 1 collaboration

Scott H Kaufmann 1 collaboration

Sandra Goble 1 collaboration

Lara Maloney 1 collaboration

Tanya Kwan 1 collaboration

Kevin K Lin 1 collaboration

Iain A McNeish 1 collaboration

R E Miller 1 collaboration

C L Scott 1 collaboration

V Serra 1 collaboration

C J Lord 1 collaboration

D Bowtell 1 collaboration

D K Chang 1 collaboration

D W Garsed 1 collaboration

J Jonkers 1 collaboration

J A Ledermann 1 collaboration

S Nik-Zainal 1 collaboration

I Ray-Coquard 1 collaboration

S P Shah 1 collaboration

X Matias-Guiu 1 collaboration

E M Swisher 1 collaboration

L R Yates 1 collaboration

E Bronsart 1 collaboration

C Petit 1 collaboration

S Gouy 1 collaboration

S Bockel 1 collaboration

S Espenel 1 collaboration

T Kumar 1 collaboration

I Fumagalli 1 collaboration

A Maulard 1 collaboration

R El Ayachy 1 collaboration

C Genestie 1 collaboration

P Pautier 1 collaboration

P Morice 1 collaboration

C Haie-Meder 1 collaboration

C Chargari 1 collaboration

Cathalijne C B Post 1 collaboration

Linda Mileshkin 1 collaboration

Dionyssios Katsaros 1 collaboration

Paul Bessette 1 collaboration

Christine Haie-Meder 1 collaboration

Nelleke P B Ottevanger 1 collaboration

Jonathan A Ledermann 1 collaboration

Romerai D'Amico 1 collaboration

Anthony Fyles 1 collaboration

Marie Hélène Baron 1 collaboration

Henry C Kitchener 1 collaboration

Ludy C H W Lutgens 1 collaboration

Susan Brooks 1 collaboration

Ina M Jürgenliemk-Schulz 1 collaboration

Amanda Feeney 1 collaboration

Geraldine Goss 1 collaboration

Roldano Fossati 1 collaboration

Viet Do 1 collaboration

Andrea A Lissoni 1 collaboration

Mary McCormack 1 collaboration

Remi A Nout 1 collaboration

Karen W Verhoeven-Adema 1 collaboration

Hein Putter 1 collaboration

Geoffrey Punshon 1 collaboration

Jo Sopala 1 collaboration

Guy Hannan 1 collaboration

Megan Roberts 1 collaboration

Karen Vernon 1 collaboration

Annabella Pearce 1 collaboration

Sabine Khalife-Hachem 1 collaboration

Khalil Saleh 1 collaboration

Florence Pasquier 1 collaboration

Christophe Willekens 1 collaboration

Anthony Tarabay 1 collaboration

Leony Antoun 1 collaboration

Thomas Grinda 1 collaboration

Cristina Castilla-Llorente 1 collaboration

Matthieu Duchmann 1 collaboration

Cyril Quivoron 1 collaboration

Nathalie Auger 1 collaboration

Veronique Saada 1 collaboration

Suzette Delaloge 1 collaboration

Aline Renneville 1 collaboration

Ileana Antony-Debre 1 collaboration

Filippo Rosselli 1 collaboration

Stéphane De Botton 1 collaboration

Flore Salviat 1 collaboration

Christophe Marzac 1 collaboration

Jean-Baptiste Micol 1 collaboration

Yuedan Zhou 1 collaboration

Sophie Espenel 1 collaboration

Samir Achkar 1 collaboration

Sebastien Gouy 1 collaboration

Cyrus Chargari 1 collaboration

Laetitia Nebot-Bral 1 collaboration

Antoine Hollebecque 1 collaboration

Andrey A Yurchenko 1 collaboration

Louise de Forceville 1 collaboration

Mathieu Danjou 1 collaboration

Jean-Mehdi Jouniaux 1 collaboration

Reginaldo C A Rosa 1 collaboration

Caroline Pouvelle 1 collaboration

Said Aoufouchi 1 collaboration

Perrine Vuagnat 1 collaboration

Cristina Smolenschi 1 collaboration

Emeline Colomba 1 collaboration

Aurelien Marabelle 1 collaboration

Jean-Yves Scoazec 1 collaboration

Lydie Cassard 1 collaboration

Sergey Nikolaev 1 collaboration

Nathalie Chaput 1 collaboration

Patricia Kannouche 1 collaboration

Lisa Vermij 1 collaboration

Alicia Léon-Castillo 1 collaboration

Naveena Singh 1 collaboration

Richard J Edmondson 1 collaboration

Jan Pyman 1 collaboration

C Meg McLachlin 1 collaboration

Emma J Crosbie 1 collaboration

Nanda Horeweg 1 collaboration

Tjalling Bosse 1 collaboration

Paul DiSilvestro 1 collaboration

Susana Banerjee 1 collaboration

Nicoletta Colombo 1 collaboration

Giovanni Scambia 1 collaboration

Byoung-Gie Kim 1 collaboration

Michael Friedlander 1 collaboration

Alla Lisyanskaya 1 collaboration

Anne Floquet 1 collaboration

Gabe S Sonke 1 collaboration

Charlie Gourley 1 collaboration

Amit Oza 1 collaboration

Antonio González-Martín 1 collaboration

William Bradley 1 collaboration

Cara Mathews 1 collaboration

Joyce Liu 1 collaboration

John McNamara 1 collaboration

Elizabeth S Lowe 1 collaboration

Mei-Lin Ah-See 1 collaboration

Kathleen N Moore 1 collaboration