Alfonso Trezza

Affiliations

Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, 53100, Italy. Electronic address: trezzaalfonso@gmail.com.

Publications (38)

The beneficial health effects of flavonoids on the cardiovascular system: Focus on K

Pharmacological research

Avec: F Fusi , A Trezza , M Tramaglino , G Sgaragli , S Saponara , O Spiga

A possible strategy to fight COVID-19: Interfering with spike glycoprotein trimerization.

Biochemical and biophysical research communications

Avec: Pietro Bongini , Alfonso Trezza , Monica Bianchini , Ottavia Spiga , Neri Niccolai

Fine tuning by protein kinases of Ca

Biochemical pharmacology

Avec: F Fusi , P Mugnai , A Trezza , O Spiga , G Sgaragli

Cervicomedullary Gliomas in Pediatric Age: A Systematic Review of the Literature and Tertiary Care Center Experience.

Pediatric neurosurgery

Avec: Andrea Trezza , Camilla de Laurentis , Veronica Biassoni , Giorgio G Carrabba , Elisabetta Schiavello , Francesco Canonico , Paolo Remida , Alessandra Moretto , Maura Massimino , Carlo Giussani

Functional, electrophysiology, and molecular dynamics analysis of quercetin-induced contraction of rat vascular musculature.

European journal of pharmacology

Avec: Alfonso Trezza , Ottavia Spiga , Paolo Mugnai , Simona Saponara , Giampietro Sgaragli , Fabio Fusi

Repurposing

Life (Basel, Switzerland)

Avec: Luisa Frusciante , Michela Geminiani , Tommaso Olmastroni , Pierfrancesco Mastroeni , Alfonso Trezza , Laura Salvini , Stefania Lamponi , Ottavia Spiga , Annalisa Santucci

Effect of acute meal and long-term intake of a Mediterranean Diet providing different amounts of carbohydrates on physical performance and biomarkers in non-professional strength athletes.

International journal of food sciences and nutrition

Avec: Simone Perna , Christian Doria , Alice Trezza , Massimiliano Tucci , Daniela Martini , Cristian Del Bo' , Ellis Bianchi , Marta Borrelli , Valentina Vinelli , Alessandro Leone , Sara Mambrini , Simona Bertoli , Emiliano Cè , Alberto Battezzati , Marisa Porrini , Fabio Esposito , Patrizia Riso

Exploring the Antioxidant and Anti-Inflammatory Potential of Saffron (

Antioxidants (Basel, Switzerland)

Avec: Luisa Frusciante , Michela Geminiani , Behnaz Shabab , Tommaso Olmastroni , Giorgia Scavello , Martina Rossi , Pierfrancesco Mastroeni , Collins Nyaberi Nyong'a , Laura Salvini , Stefania Lamponi , Maria Laura Parisi , Adalgisa Sinicropi , Lorenzo Costa , Ottavia Spiga , Alfonso Trezza , Annalisa Santucci

Ritanserin blocks Ca

Acta pharmacologica Sinica

Avec: Fabio Fusi , Alfonso Trezza , Giampietro Sgaragli , Ottavia Spiga , Simona Saponara , Sergio Bova

Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators.

European journal of medicinal chemistry

Avec: Silvia Dei , Laura Braconi , Alfonso Trezza , Marta Menicatti , Marialessandra Contino , Marcella Coronnello , Niccolò Chiaramonte , Dina Manetti , Maria Grazia Perrone , Maria Novella Romanelli , Chatchanok Udomtanakunchai , Nicola Antonio Colabufo , Gianluca Bartolucci , Ottavia Spiga , Milena Salerno , Elisabetta Teodori

Structural Bioinformatic Survey of Protein-Small Molecule Interfaces Delineates the Role of Glycine in Surface Pocket Formation.

IEEE/ACM transactions on computational biology and bioinformatics

Avec: Pietro Bongini , Neri Niccolai , Alfonso Trezza , Guido Mangiavacchi , Annalisa Santucci , Ottavia Spiga , Monica Bianchini , Simone Gardini

Infant ossified cephalohematoma: a review of the surgical management and technical update.

Journal of neurosurgical sciences

Avec: Tommaso Calloni , Andrea Trezza , Fabio Mazzoleni , Marilou Cavaliere , Francesco Canonico , Erik Sganzerla , Carlo Giussani

Exoscope as a Teaching Tool: A Narrative Review of the Literature.

Frontiers in surgery

Avec: Tommaso Calloni , Louis Georges Roumy , Maria Allegra Cinalli , Alessandra Rocca , Andrea Held , Andrea Trezza , Giorgio Giovanni Carrabba , Carlo Giorgio Giussani

Effect of Vagus Nerve Stimulation on Blood Inflammatory Markers in Children with Drug-Resistant Epilepsy: A Pilot Study.

Children (Basel, Switzerland)

Avec: Valentina Baro , Maria Vittoria Bonavina , Francesco Saettini , Giovanna D'Amico , Andrea Trezza , Luca Denaro , Daniele Grioni , Andrea Landi

Posterior fossa syndrome in a population of children and young adults with medulloblastoma: a retrospective, multicenter Italian study on incidence and pathophysiology in a histologically homogeneous and consecutive series of 136 patients.

Journal of neuro-oncology

Avec: Camilla de Laurentis , Paola M F Cristaldi , Paola Rebora , Maria Grazia Valsecchi , Veronica Biassoni , Elisabetta Schiavello , Giorgio G Carrabba , Andrea Trezza , Francesco DiMeco , Paolo Ferroli , Giuseppe Cinalli , Marco Locatelli , Marco Cenzato , Giuseppe Talamonti , Marco M Fontanella , Giannatonio Spena , Roberto Stefini , Claudio Bernucci , Silvio Bellocchi , Davide Locatelli , Maura Massimino , Carlo Giussani

Alkaptonuria: From Molecular Insights to a Dedicated Digital Platform.

Cells

Avec: Maria Serena Milella , Michela Geminiani , Alfonso Trezza , Anna Visibelli , Daniela Braconi , Annalisa Santucci

From Microscopic to Exoscopic Microsurgery: Are We Facing a Change of Paradigm?

Advances and technical standards in neurosurgery

Avec: Andrea Di Cristofori , Camilla de Laurentis , Andrea Trezza , Alberto Ramponi , Giorgio Carrabba , Carlo Giussani

Design, synthesis and biological evaluation of stereo- and regioisomers of amino aryl esters as multidrug resistance (MDR) reversers.

European journal of medicinal chemistry

Avec: Elisabetta Teodori , Marialessandra Contino , Chiara Riganti , Gianluca Bartolucci , Laura Braconi , Dina Manetti , Maria Novella Romanelli , Alfonso Trezza , Asimidis Athanasios , Ottavia Spiga , Maria Grazia Perrone , Roberta Giampietro , Elena Gazzano , Milena Salerno , Nicola Antonio Colabufo , Silvia Dei

An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors.

Scientific reports

Avec: Alfonso Trezza , Daniele Iovinelli , Annalisa Santucci , Filippo Prischi , Ottavia Spiga

In Silico Multi-Target Approach Revealed Potential Lead Compounds as Scaffold for the Synthesis of Chemical Analogues Targeting SARS-CoV-2.

Biology

Avec: Alfonso Trezza , Claudia Mugnaini , Federico Corelli , Annalisa Santucci , Ottavia Spiga

Phytochemical Composition, Anti-Inflammatory Property, and Anti-Atopic Effect of

Marine drugs

Avec: Luisa Frusciante , Michela Geminiani , Alfonso Trezza , Tommaso Olmastroni , Pierfrancesco Mastroeni , Laura Salvini , Stefania Lamponi , Andrea Bernini , Daniela Grasso , Elena Dreassi , Ottavia Spiga , Annalisa Santucci

Molecular and Evolution

Biomedicines

Avec: Alfonso Trezza , Ancuta Birgauan , Michela Geminiani , Anna Visibelli , Annalisa Santucci

Deep brain stimulation for Parkinson's disease in practice: results of the survey by the Italian Neurosurgery Society.

Journal of neurosurgical sciences

Avec: Fabrizio Mancini , Giusy Guzzi , Corrado F Castrioto , Michele A Cavallo , Alfredo Conti , Carlo Conti , Attilio Della Torre , Felice Esposito , Giuseppina Iorio , Andrea Landi , Michele Lanotte , Angelo Lavano , Marco Locatelli , Michele Longhi , Daniele Marruzzo , Massimo Mondani , Roberta Morace , Manuel Pellizzari , Massimo Piacentino , Piero Picozzi , Francesco Romeo , Silvio Sarrubbo , Domenico Servello , Teresa Somma , Andrea Trezza , Giovanni Tringali , Tommaso Tufo , Riccardo A Ricciuti

The drp-1-mediated mitochondrial fission inhibitor mdivi-1 impacts the function of ion channels and pathways underpinning vascular smooth muscle tone.

Biochemical pharmacology

Avec: Amer Ahmed , Alfonso Trezza , Mariangela Gentile , Eugenio Paccagnini , Pietro Lupetti , Ottavia Spiga , Sergio Bova , Fabio Fusi

Early-stage cervical cancer treatment - what's new?

Przeglad menopauzalny = Menopause review

Avec: Camilla Di Dio , Ilham Azenkoud , Angelo Trezza , Emanuele Lentini , Tullio Golia D'Augè , Ilaria Cuccu , Giorgia Di Bartolomeo , Ilaria Firulli , Andrea Canicchio , Ludovica Sgamba , Ludovico Muzii

Boosting teamwork between scrub nurses and neurosurgeons: exploring the value of a role-played hands-on, cadaver-free simulation and systematic review of the literature.

Frontiers in surgery

Avec: Camilla de Laurentis , David Pirillo , Andrea Di Cristofori , Alessandro Versace , Tommaso Calloni , Andrea Trezza , Valentina Villa , Lucia Alberti , Angelo Baldo , Federico Nicolosi , Giorgio Carrabba , Carlo Giussani

HGA Triggers SAA Aggregation and Accelerates Fibril Formation in the C20/A4 Alkaptonuria Cell Model.

Cells

Avec: Pierfrancesco Mastroeni , Alfonso Trezza , Michela Geminiani , Luisa Frusciante , Anna Visibelli , Annalisa Santucci

Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease.

Orphanet journal of rare diseases

Avec: Ottavia Spiga , Vittoria Cicaloni , Cosimo Fiorini , Alfonso Trezza , Anna Visibelli , Lia Millucci , Giulia Bernardini , Andrea Bernini , Barbara Marzocchi , Daniela Braconi , Filippo Prischi , Annalisa Santucci

Applications of in Silico Methods for Design and Development of Drugs Targeting Protein-Protein Interactions.

Current topics in medicinal chemistry

Avec: Vittoria Cicaloni , Alfonso Trezza , Francesco Pettini , Ottavia Spiga

Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer.

Bioorganic chemistry

Avec: Jessica Caciolla , Giovanna Picone , Giovanna Farruggia , Dario Valenti , Angela Rampa , Emil Malucelli , Federica Belluti , Alfonso Trezza , Ottavia Spiga , Stefano Iotti , Silvia Gobbi , Concettina Cappadone , Alessandra Bisi

Intraoperative MRI versus intraoperative ultrasound in pediatric brain tumor surgery: is expensive better than cheap? A review of the literature.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Avec: Carlo Giussani , Andrea Trezza , Vittorio Ricciuti , Andrea Di Cristofori , Andrea Held , Valeria Isella , Maura Massimino

Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts.

Bioorganic chemistry

Avec: Alessandra Bisi , Alessandra Feoli , Alfonso Trezza , Lucia Viejo , Francesco Formaggio , Manuela Bartolini , Federica Belluti , Silvia Gobbi , Ottavia Spiga , Marco Caprini , Cristobal de Los Rios , Sabrina Castellano , Angela Rampa

Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits Ca

Marine drugs

Avec: Gabriele Carullo , Simona Saponara , Amer Ahmed , Beatrice Gorelli , Sarah Mazzotta , Alfonso Trezza , Beatrice Gianibbi , Giuseppe Campiani , Fabio Fusi , Francesca Aiello

Exoscopic microneurosurgery in pediatric brain tumors: an ideal tool for complex and peculiar anatomo-topographic scenarios?

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Avec: Andrea Trezza , Camilla de Laurentis , Giorgio Giovanni Carrabba , Maura Massimino , Veronica Biassoni , Arianna Doro , Chiara Vimercati , Carlo Giorgio Giussani

Role of aquaporins in hydrocephalus: what do we know and where do we stand? A systematic review.

Journal of neurology

Avec: Camilla de Laurentis , Paola Cristaldi , Andrea Arighi , Clarissa Cavandoli , Andrea Trezza , Erik P Sganzerla , Carlo G Giussani , Andrea Di Cristofori

ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population.

European journal of human genetics : EJHG

Avec: Elisa Benetti , Rossella Tita , Ottavia Spiga , Andrea Ciolfi , Giovanni Birolo , Alessandro Bruselles , Gabriella Doddato , Annarita Giliberti , Caterina Marconi , Francesco Musacchia , Tommaso Pippucci , Annalaura Torella , Alfonso Trezza , Floriana Valentino , Margherita Baldassarri , Alfredo Brusco , Rosanna Asselta , Mirella Bruttini , Simone Furini , Marco Seri , Vincenzo Nigro , Giuseppe Matullo , Marco Tartaglia , Francesca Mari , Auteur inconnu , Alessandra Renieri , Anna Maria Pinto

Retrospective analysis of the clinical and radiological features of 94 consecutive DIPGs patients to investigate the factors determining the development of hydrocephalus and its impact on clinical status and survival.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

Avec: Carlo Giussani , Lelio Guida , Veronica Biassoni , Elisabetta Schiavello , Giorgio Carrabba , Andrea Trezza , Erik Sganzerla , Maura Massimino

The Selective Rat Toxicant Norbormide Blocks K

Frontiers in pharmacology

Avec: Simona Saponara , Fabio Fusi , Ottavia Spiga , Alfonso Trezza , Brian Hopkins , Margaret A Brimble , David Rennison , Sergio Bova

Réseau de co-auteurs

Ottavia Spiga 18 collaborations

Andrea Trezza 12 collaborations

Annalisa Santucci 10 collaborations

Carlo Giussani 7 collaborations

Camilla de Laurentis 6 collaborations

Michela Geminiani 6 collaborations

Maura Massimino 5 collaborations

Fabio Fusi 5 collaborations

Veronica Biassoni 4 collaborations

Simona Saponara 4 collaborations

Luisa Frusciante 4 collaborations

Pierfrancesco Mastroeni 4 collaborations

Anna Visibelli 4 collaborations

Andrea Di Cristofori 4 collaborations

Elisabetta Schiavello 3 collaborations

Tommaso Olmastroni 3 collaborations

Laura Salvini 3 collaborations

Stefania Lamponi 3 collaborations

Sergio Bova 3 collaborations

Tommaso Calloni 3 collaborations

Giorgio Carrabba 3 collaborations

F Fusi 2 collaborations

A Trezza 2 collaborations

G Sgaragli 2 collaborations

O Spiga 2 collaborations

Pietro Bongini 2 collaborations

Monica Bianchini 2 collaborations

Neri Niccolai 2 collaborations

Giorgio G Carrabba 2 collaborations

Francesco Canonico 2 collaborations

Giampietro Sgaragli 2 collaborations

Silvia Dei 2 collaborations

Laura Braconi 2 collaborations

Marialessandra Contino 2 collaborations

Dina Manetti 2 collaborations

Maria Grazia Perrone 2 collaborations

Maria Novella Romanelli 2 collaborations

Nicola Antonio Colabufo 2 collaborations

Gianluca Bartolucci 2 collaborations

Milena Salerno 2 collaborations

Elisabetta Teodori 2 collaborations

Erik Sganzerla 2 collaborations

Andrea Held 2 collaborations

Giorgio Giovanni Carrabba 2 collaborations

Carlo Giorgio Giussani 2 collaborations

Andrea Landi 2 collaborations

Marco Locatelli 2 collaborations

Daniela Braconi 2 collaborations

Filippo Prischi 2 collaborations

Andrea Bernini 2 collaborations

Amer Ahmed 2 collaborations

Vittoria Cicaloni 2 collaborations

Angela Rampa 2 collaborations

Federica Belluti 2 collaborations

Silvia Gobbi 2 collaborations

Alessandra Bisi 2 collaborations

M Tramaglino 1 collaboration

S Saponara 1 collaboration

P Mugnai 1 collaboration

Paolo Remida 1 collaboration

Alessandra Moretto 1 collaboration

Paolo Mugnai 1 collaboration

Simone Perna 1 collaboration

Christian Doria 1 collaboration

Alice Trezza 1 collaboration

Massimiliano Tucci 1 collaboration

Daniela Martini 1 collaboration

Cristian Del Bo' 1 collaboration

Ellis Bianchi 1 collaboration

Marta Borrelli 1 collaboration

Valentina Vinelli 1 collaboration

Alessandro Leone 1 collaboration

Sara Mambrini 1 collaboration

Simona Bertoli 1 collaboration

Emiliano Cè 1 collaboration

Alberto Battezzati 1 collaboration

Marisa Porrini 1 collaboration

Fabio Esposito 1 collaboration

Patrizia Riso 1 collaboration

Behnaz Shabab 1 collaboration

Giorgia Scavello 1 collaboration

Martina Rossi 1 collaboration

Collins Nyaberi Nyong'a 1 collaboration

Maria Laura Parisi 1 collaboration

Adalgisa Sinicropi 1 collaboration

Lorenzo Costa 1 collaboration

Marta Menicatti 1 collaboration

Marcella Coronnello 1 collaboration

Niccolò Chiaramonte 1 collaboration

Chatchanok Udomtanakunchai 1 collaboration

Guido Mangiavacchi 1 collaboration

Simone Gardini 1 collaboration

Fabio Mazzoleni 1 collaboration

Marilou Cavaliere 1 collaboration

Louis Georges Roumy 1 collaboration

Maria Allegra Cinalli 1 collaboration

Alessandra Rocca 1 collaboration

Valentina Baro 1 collaboration

Maria Vittoria Bonavina 1 collaboration

Francesco Saettini 1 collaboration

Giovanna D'Amico 1 collaboration

Luca Denaro 1 collaboration

Daniele Grioni 1 collaboration

Paola M F Cristaldi 1 collaboration

Paola Rebora 1 collaboration

Maria Grazia Valsecchi 1 collaboration

Francesco DiMeco 1 collaboration

Paolo Ferroli 1 collaboration

Giuseppe Cinalli 1 collaboration

Marco Cenzato 1 collaboration

Giuseppe Talamonti 1 collaboration

Marco M Fontanella 1 collaboration

Giannatonio Spena 1 collaboration

Roberto Stefini 1 collaboration

Claudio Bernucci 1 collaboration

Silvio Bellocchi 1 collaboration

Davide Locatelli 1 collaboration

Maria Serena Milella 1 collaboration

Alberto Ramponi 1 collaboration

Chiara Riganti 1 collaboration

Asimidis Athanasios 1 collaboration

Roberta Giampietro 1 collaboration

Elena Gazzano 1 collaboration

Daniele Iovinelli 1 collaboration

Claudia Mugnaini 1 collaboration

Federico Corelli 1 collaboration

Daniela Grasso 1 collaboration

Elena Dreassi 1 collaboration

Ancuta Birgauan 1 collaboration

Fabrizio Mancini 1 collaboration

Giusy Guzzi 1 collaboration

Corrado F Castrioto 1 collaboration

Michele A Cavallo 1 collaboration

Alfredo Conti 1 collaboration

Carlo Conti 1 collaboration

Attilio Della Torre 1 collaboration

Felice Esposito 1 collaboration

Giuseppina Iorio 1 collaboration

Michele Lanotte 1 collaboration

Angelo Lavano 1 collaboration

Michele Longhi 1 collaboration

Daniele Marruzzo 1 collaboration

Massimo Mondani 1 collaboration

Roberta Morace 1 collaboration

Manuel Pellizzari 1 collaboration

Massimo Piacentino 1 collaboration

Piero Picozzi 1 collaboration

Francesco Romeo 1 collaboration

Silvio Sarrubbo 1 collaboration

Domenico Servello 1 collaboration

Teresa Somma 1 collaboration

Giovanni Tringali 1 collaboration

Tommaso Tufo 1 collaboration

Riccardo A Ricciuti 1 collaboration

Mariangela Gentile 1 collaboration

Eugenio Paccagnini 1 collaboration

Pietro Lupetti 1 collaboration

Camilla Di Dio 1 collaboration

Ilham Azenkoud 1 collaboration

Angelo Trezza 1 collaboration

Emanuele Lentini 1 collaboration

Tullio Golia D'Augè 1 collaboration

Ilaria Cuccu 1 collaboration

Giorgia Di Bartolomeo 1 collaboration

Ilaria Firulli 1 collaboration

Andrea Canicchio 1 collaboration

Ludovica Sgamba 1 collaboration

Ludovico Muzii 1 collaboration

David Pirillo 1 collaboration

Alessandro Versace 1 collaboration

Valentina Villa 1 collaboration

Lucia Alberti 1 collaboration

Angelo Baldo 1 collaboration

Federico Nicolosi 1 collaboration

Cosimo Fiorini 1 collaboration

Lia Millucci 1 collaboration

Giulia Bernardini 1 collaboration

Barbara Marzocchi 1 collaboration

Francesco Pettini 1 collaboration

Jessica Caciolla 1 collaboration

Giovanna Picone 1 collaboration

Giovanna Farruggia 1 collaboration

Dario Valenti 1 collaboration

Emil Malucelli 1 collaboration

Stefano Iotti 1 collaboration

Concettina Cappadone 1 collaboration

Vittorio Ricciuti 1 collaboration

Valeria Isella 1 collaboration

Alessandra Feoli 1 collaboration

Lucia Viejo 1 collaboration

Francesco Formaggio 1 collaboration

Manuela Bartolini 1 collaboration

Marco Caprini 1 collaboration

Cristobal de Los Rios 1 collaboration

Sabrina Castellano 1 collaboration

Gabriele Carullo 1 collaboration

Beatrice Gorelli 1 collaboration

Sarah Mazzotta 1 collaboration

Beatrice Gianibbi 1 collaboration

Giuseppe Campiani 1 collaboration

Francesca Aiello 1 collaboration

Arianna Doro 1 collaboration

Chiara Vimercati 1 collaboration

Paola Cristaldi 1 collaboration

Andrea Arighi 1 collaboration

Clarissa Cavandoli 1 collaboration

Erik P Sganzerla 1 collaboration

Carlo G Giussani 1 collaboration

Elisa Benetti 1 collaboration

Rossella Tita 1 collaboration

Andrea Ciolfi 1 collaboration

Giovanni Birolo 1 collaboration

Alessandro Bruselles 1 collaboration

Gabriella Doddato 1 collaboration

Annarita Giliberti 1 collaboration

Caterina Marconi 1 collaboration

Francesco Musacchia 1 collaboration

Tommaso Pippucci 1 collaboration

Annalaura Torella 1 collaboration

Floriana Valentino 1 collaboration

Margherita Baldassarri 1 collaboration

Alfredo Brusco 1 collaboration

Rosanna Asselta 1 collaboration

Mirella Bruttini 1 collaboration

Simone Furini 1 collaboration

Marco Seri 1 collaboration

Vincenzo Nigro 1 collaboration

Giuseppe Matullo 1 collaboration

Marco Tartaglia 1 collaboration

Francesca Mari 1 collaboration

None None 1 collaboration

Alessandra Renieri 1 collaboration

Anna Maria Pinto 1 collaboration

Lelio Guida 1 collaboration

Brian Hopkins 1 collaboration

Margaret A Brimble 1 collaboration

David Rennison 1 collaboration