Andrew E Teschendorff

Affiliations

CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Statistical Genomics Group, UCL Cancer Institute, University College London, London WC1E 6BT, UK.

Publications (38)

eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data.

Bioinformatics (Oxford, England)

Avec: Charles E Breeze , Alex P Reynolds , Jenny van Dongen , Ian Dunham , John Lazar , Shane Neph , Jeff Vierstra , Guillaume Bourque , Andrew E Teschendorff , John A Stamatoyannopoulos , Stephan Beck

A comparison of epigenetic mitotic-like clocks for cancer risk prediction.

Genome medicine

Avec: Andrew E Teschendorff

Improved detection of tumor suppressor events in single-cell RNA-Seq data.

NPJ genomic medicine

Avec: Andrew E Teschendorff , Ning Wang

Novel epigenetic network biomarkers for early detection of esophageal cancer.

Clinical epigenetics

Avec: Alok K Maity , Timothy C Stone , Vanessa Ward , Amy P Webster , Zhen Yang , Aine Hogan , Hazel McBain , Margaraet Duku , Kai Man Alexander Ho , Paul Wolfson , David G Graham , Auteur inconnu , Stephan Beck , Andrew E Teschendorff , Laurence B Lovat

Quantifying the stochastic component of epigenetic aging.

Nature aging

Avec: Huige Tong , Varun B Dwaraka , Qingwen Chen , Qi Luo , Jessica A Lasky-Su , Ryan Smith , Andrew E Teschendorff

DNA methylation aging clocks: challenges and recommendations.

Genome biology

Avec: Christopher G Bell , Robert Lowe , Peter D Adams , Andrea A Baccarelli , Stephan Beck , Jordana T Bell , Brock C Christensen , Vadim N Gladyshev , Bastiaan T Heijmans , Steve Horvath , Trey Ideker , Jean-Pierre J Issa , Karl T Kelsey , Riccardo E Marioni , Wolf Reik , Caroline L Relton , Leonard C Schalkwyk , Andrew E Teschendorff , Wolfgang Wagner , Kang Zhang , Vardhman K Rakyan

ebGSEA: an improved Gene Set Enrichment Analysis method for Epigenome-Wide-Association Studies.

Bioinformatics (Oxford, England)

Avec: Danyue Dong , Yuan Tian , Shijie C Zheng , Andrew E Teschendorff

Accounting for differential variability in detecting differentially methylated regions.

Briefings in bioinformatics

Avec: Ya Wang , Andrew E Teschendorff , Martin Widschwendter , Shuang Wang

Ultra-fast scalable estimation of single-cell differentiation potency from scRNA-Seq data.

Bioinformatics (Oxford, England)

Avec: Andrew E Teschendorff , Alok K Maity , Xue Hu , Chen Weiyan , Matthias Lechner

Statistical mechanics meets single-cell biology.

Nature reviews. Genetics

Avec: Andrew E Teschendorff , Andrew P Feinberg

A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes.

Nature communications

Avec: Chenglong You , Sijie Wu , Shijie C Zheng , Tianyu Zhu , Han Jing , Ken Flagg , Guangyu Wang , Li Jin , Sijia Wang , Andrew E Teschendorff

Detection of Epigenetic Field Defects Using a Weighted Epigenetic Distance-Based Method.

Methods in molecular biology (Clifton, N.J.)

Avec: Ya Wang , Min Qian , Peifeng Ruan , Andrew E Teschendorff , Shuang Wang

Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome.

Communications biology

Avec: Weiyan Chen , Samuel J Morabito , Kai Kessenbrock , Tariq Enver , Kerstin B Meyer , Andrew E Teschendorff

Detection of epigenetic field defects using a weighted epigenetic distance-based method.

Nucleic acids research

Avec: Ya Wang , Min Qian , Peifeng Ruan , Andrew E Teschendorff , Shuang Wang

Cell-type heterogeneity: Why we should adjust for it in epigenome and biomarker studies.

Clinical epigenetics

Avec: Luo Qi , Andrew E Teschendorff

Insights into the role of long non-coding RNAs in DNA methylation mediated transcriptional regulation.

Frontiers in molecular biosciences

Avec: Zhen Yang , Feng Xu , Andrew E Teschendorff , Yi Zhao , Lei Yao , Jian Li , Yungang He

Cell-Type Deconvolution of Bulk DNA Methylation Data with EpiSCORE.

Methods in molecular biology (Clifton, N.J.)

Avec: Tianyu Zhu , Andrew E Teschendorff

Challenges and perspectives in computational deconvolution of genomics data.

Nature methods

Avec: Lana X Garmire , Yijun Li , Qianhui Huang , Chuan Xu , Sarah A Teichmann , Naftali Kaminski , Matteo Pellegrini , Quan Nguyen , Andrew E Teschendorff

Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity and immune evasion in lower grade glioma.

Communications biology

Avec: Zhen Yang , Xiaocen Liu , Hao Xu , Andrew E Teschendorff , Lingjie Xu , Jingyi Li , Minjie Fu , Jun Liu , Hanyu Zhou , Yingying Wang , Licheng Zhang , Yungang He , Kun Lv , Hui Yang

Longitudinal analysis of epigenome-wide DNA methylation reveals novel loci associated with BMI change in East Asians.

Clinical epigenetics

Avec: Wenran Li , Mingfeng Xia , Hailuan Zeng , Huandong Lin , Andrew E Teschendorff , Xin Gao , Sijia Wang

Appraising the causal relevance of DNA methylation for risk of lung cancer.

International journal of epidemiology

Avec: Thomas Battram , Rebecca C Richmond , Laura Baglietto , Philip C Haycock , Vittorio Perduca , Stig E Bojesen , Tom R Gaunt , Gibran Hemani , Florence Guida , Robert Carreras-Torres , Rayjean Hung , Christopher I Amos , Joshua R Freeman , Torkjel M Sandanger , Therese H Nøst , Børge G Nordestgaard , Andrew E Teschendorff , Silvia Polidoro , Paolo Vineis , Gianluca Severi , Allison M Hodge , Graham G Giles , Kjell Grankvist , Mikael B Johansson , Mattias Johansson , George Davey Smith , Caroline L Relton

Quantifying Waddington's epigenetic landscape: a comparison of single-cell potency measures.

Briefings in bioinformatics

Avec: Jifan Shi , Andrew E Teschendorff , Weiyan Chen , Luonan Chen , Tiejun Li

Computational Identification of Preneoplastic Cells Displaying High Stemness and Risk of Cancer Progression.

Cancer research

Avec: Tianyuan Liu , Xuan Zhao , Yuan Lin , Qi Luo , Shaosen Zhang , Yiyi Xi , Yamei Chen , Lin Lin , Wenyi Fan , Jie Yang , Yuling Ma , Alok K Maity , Yanyi Huang , Jianbin Wang , Jiang Chang , Dongxin Lin , Andrew E Teschendorff , Chen Wu

Pan-cancer characterization of long non-coding RNA and DNA methylation mediated transcriptional dysregulation.

EBioMedicine

Avec: Zhen Yang , Feng Xu , Haizhou Wang , Andrew E Teschendorff , Feng Xie , Yungang He

An improved epigenetic counter to track mitotic age in normal and precancerous tissues.

Nature communications

Avec: Tianyu Zhu , Huige Tong , Zhaozhen Du , Stephan Beck , Andrew E Teschendorff

Inference of age-associated transcription factor regulatory activity changes in single cells.

Nature aging

Avec: Alok K Maity , Xue Hu , Tianyu Zhu , Andrew E Teschendorff

Distance covariance entropy reveals primed states and bifurcation dynamics in single-cell RNA-Seq data.

iScience

Avec: Qi Luo , Alok K Maity , Andrew E Teschendorff

Computational single-cell methods for predicting cancer risk.

Biochemical Society transactions

Avec: Andrew E Teschendorff

EpiDISH web server: Epigenetic Dissection of Intra-Sample-Heterogeneity with online GUI.

Bioinformatics (Oxford, England)

Avec: Shijie C Zheng , Charles E Breeze , Stephan Beck , Danyue Dong , Tianyu Zhu , Liangxiao Ma , Wei Ye , Guoqing Zhang , Andrew E Teschendorff

Estimating Differentiation Potency of Single Cells Using Single-Cell Entropy (SCENT).

Methods in molecular biology (Clifton, N.J.)

Avec: Weiyan Chen , Andrew E Teschendorff

EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data.

Genome biology

Avec: Andrew E Teschendorff , Tianyu Zhu , Charles E Breeze , Stephan Beck

A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation.

Epigenetics

Avec: Yen Ting Wong , Michael A Tayeb , Timothy C Stone , Laurence B Lovat , Andrew E Teschendorff , Rafal Iwasiow , Jeffrey M Craig

A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution.

Nature methods

Avec: Tianyu Zhu , Jacklyn Liu , Stephan Beck , Sun Pan , David Capper , Matt Lechner , Chrissie Thirlwell , Charles E Breeze , Andrew E Teschendorff

dbDEMC 3.0: Functional Exploration of Differentially Expressed miRNAs in Cancers of Human and Model Organisms.

Genomics, proteomics & bioinformatics

Avec: Feng Xu , Yifan Wang , Yunchao Ling , Chenfen Zhou , Haizhou Wang , Andrew E Teschendorff , Yi Zhao , Haitao Zhao , Yungang He , Guoqing Zhang , Zhen Yang

On epigenetic stochasticity, entropy and cancer risk.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Avec: Andrew E Teschendorff

Analysis of blood methylation quantitative trait loci in East Asians reveals ancestry-specific impacts on complex traits.

Nature genetics

Avec: Qianqian Peng , Xinxuan Liu , Wenran Li , Han Jing , Jiarui Li , Xingjian Gao , Qi Luo , Charles E Breeze , Siyu Pan , Qiwen Zheng , Guochao Li , Jiaqiang Qian , Liyun Yuan , Na Yuan , Chenglong You , Siyuan Du , Yuanting Zheng , Ziyu Yuan , Jingze Tan , Peilin Jia , Jiucun Wang , Guoqing Zhang , Xianping Lu , Leming Shi , Shicheng Guo , Yun Liu , Ting Ni , Bo Wen , Changqing Zeng , Li Jin , Andrew E Teschendorff , Fan Liu , Sijia Wang

A meta-analysis of immune-cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes.

Genome medicine

Avec: Qi Luo , Varun B Dwaraka , Qingwen Chen , Huige Tong , Tianyu Zhu , Kirsten Seale , Joseph M Raffaele , Shijie C Zheng , Tavis L Mendez , Yulu Chen , Natalia Carreras , Sofina Begum , Kevin Mendez , Sarah Voisin , Nir Eynon , Jessica A Lasky-Su , Ryan Smith , Andrew E Teschendorff

Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data.

Nature communications

Avec: Alok K Maity , Andrew E Teschendorff

Réseau de co-auteurs

Tianyu Zhu 8 collaborations

Stephan Beck 7 collaborations

Alok K Maity 6 collaborations

Charles E Breeze 5 collaborations

Zhen Yang 5 collaborations

Qi Luo 5 collaborations

Shijie C Zheng 4 collaborations

Yungang He 4 collaborations

Huige Tong 3 collaborations

Ya Wang 3 collaborations

Shuang Wang 3 collaborations

Sijia Wang 3 collaborations

Weiyan Chen 3 collaborations

Feng Xu 3 collaborations

Guoqing Zhang 3 collaborations

Timothy C Stone 2 collaborations

Laurence B Lovat 2 collaborations

Varun B Dwaraka 2 collaborations

Qingwen Chen 2 collaborations

Jessica A Lasky-Su 2 collaborations

Ryan Smith 2 collaborations

Caroline L Relton 2 collaborations

Danyue Dong 2 collaborations

Xue Hu 2 collaborations

Chenglong You 2 collaborations

Han Jing 2 collaborations

Li Jin 2 collaborations

Min Qian 2 collaborations

Peifeng Ruan 2 collaborations

Yi Zhao 2 collaborations

Wenran Li 2 collaborations

Haizhou Wang 2 collaborations

Alex P Reynolds 1 collaboration

Jenny van Dongen 1 collaboration

Ian Dunham 1 collaboration

John Lazar 1 collaboration

Shane Neph 1 collaboration

Jeff Vierstra 1 collaboration

Guillaume Bourque 1 collaboration

John A Stamatoyannopoulos 1 collaboration

Ning Wang 1 collaboration

Vanessa Ward 1 collaboration

Amy P Webster 1 collaboration

Aine Hogan 1 collaboration

Hazel McBain 1 collaboration

Margaraet Duku 1 collaboration

Kai Man Alexander Ho 1 collaboration

Paul Wolfson 1 collaboration

David G Graham 1 collaboration

None None 1 collaboration

Christopher G Bell 1 collaboration

Robert Lowe 1 collaboration

Peter D Adams 1 collaboration

Andrea A Baccarelli 1 collaboration

Jordana T Bell 1 collaboration

Brock C Christensen 1 collaboration

Vadim N Gladyshev 1 collaboration

Bastiaan T Heijmans 1 collaboration

Steve Horvath 1 collaboration

Trey Ideker 1 collaboration

Jean-Pierre J Issa 1 collaboration

Karl T Kelsey 1 collaboration

Riccardo E Marioni 1 collaboration

Wolf Reik 1 collaboration

Leonard C Schalkwyk 1 collaboration

Wolfgang Wagner 1 collaboration

Kang Zhang 1 collaboration

Vardhman K Rakyan 1 collaboration

Yuan Tian 1 collaboration

Martin Widschwendter 1 collaboration

Chen Weiyan 1 collaboration

Matthias Lechner 1 collaboration

Andrew P Feinberg 1 collaboration

Sijie Wu 1 collaboration

Ken Flagg 1 collaboration

Guangyu Wang 1 collaboration

Samuel J Morabito 1 collaboration

Kai Kessenbrock 1 collaboration

Tariq Enver 1 collaboration

Kerstin B Meyer 1 collaboration

Luo Qi 1 collaboration

Lei Yao 1 collaboration

Jian Li 1 collaboration

Lana X Garmire 1 collaboration

Yijun Li 1 collaboration

Qianhui Huang 1 collaboration

Chuan Xu 1 collaboration

Sarah A Teichmann 1 collaboration

Naftali Kaminski 1 collaboration

Matteo Pellegrini 1 collaboration

Quan Nguyen 1 collaboration

Xiaocen Liu 1 collaboration

Hao Xu 1 collaboration

Lingjie Xu 1 collaboration

Jingyi Li 1 collaboration

Minjie Fu 1 collaboration

Jun Liu 1 collaboration

Hanyu Zhou 1 collaboration

Yingying Wang 1 collaboration

Licheng Zhang 1 collaboration

Kun Lv 1 collaboration

Hui Yang 1 collaboration

Mingfeng Xia 1 collaboration

Hailuan Zeng 1 collaboration

Huandong Lin 1 collaboration

Xin Gao 1 collaboration

Thomas Battram 1 collaboration

Rebecca C Richmond 1 collaboration

Laura Baglietto 1 collaboration

Philip C Haycock 1 collaboration

Vittorio Perduca 1 collaboration

Stig E Bojesen 1 collaboration

Tom R Gaunt 1 collaboration

Gibran Hemani 1 collaboration

Florence Guida 1 collaboration

Robert Carreras-Torres 1 collaboration

Rayjean Hung 1 collaboration

Christopher I Amos 1 collaboration

Joshua R Freeman 1 collaboration

Torkjel M Sandanger 1 collaboration

Therese H Nøst 1 collaboration

Børge G Nordestgaard 1 collaboration

Silvia Polidoro 1 collaboration

Paolo Vineis 1 collaboration

Gianluca Severi 1 collaboration

Allison M Hodge 1 collaboration

Graham G Giles 1 collaboration

Kjell Grankvist 1 collaboration

Mikael B Johansson 1 collaboration

Mattias Johansson 1 collaboration

George Davey Smith 1 collaboration

Jifan Shi 1 collaboration

Luonan Chen 1 collaboration

Tiejun Li 1 collaboration

Tianyuan Liu 1 collaboration

Xuan Zhao 1 collaboration

Yuan Lin 1 collaboration

Shaosen Zhang 1 collaboration

Yiyi Xi 1 collaboration

Yamei Chen 1 collaboration

Lin Lin 1 collaboration

Wenyi Fan 1 collaboration

Jie Yang 1 collaboration

Yuling Ma 1 collaboration

Yanyi Huang 1 collaboration

Jianbin Wang 1 collaboration

Jiang Chang 1 collaboration

Dongxin Lin 1 collaboration

Chen Wu 1 collaboration

Feng Xie 1 collaboration

Zhaozhen Du 1 collaboration

Liangxiao Ma 1 collaboration

Wei Ye 1 collaboration

Yen Ting Wong 1 collaboration

Michael A Tayeb 1 collaboration

Rafal Iwasiow 1 collaboration

Jeffrey M Craig 1 collaboration

Jacklyn Liu 1 collaboration

Sun Pan 1 collaboration

David Capper 1 collaboration

Matt Lechner 1 collaboration

Chrissie Thirlwell 1 collaboration

Yifan Wang 1 collaboration

Yunchao Ling 1 collaboration

Chenfen Zhou 1 collaboration

Haitao Zhao 1 collaboration

Qianqian Peng 1 collaboration

Xinxuan Liu 1 collaboration

Jiarui Li 1 collaboration

Xingjian Gao 1 collaboration

Siyu Pan 1 collaboration

Qiwen Zheng 1 collaboration

Guochao Li 1 collaboration

Jiaqiang Qian 1 collaboration

Liyun Yuan 1 collaboration

Na Yuan 1 collaboration

Siyuan Du 1 collaboration

Yuanting Zheng 1 collaboration

Ziyu Yuan 1 collaboration

Jingze Tan 1 collaboration

Peilin Jia 1 collaboration

Jiucun Wang 1 collaboration

Xianping Lu 1 collaboration

Leming Shi 1 collaboration

Shicheng Guo 1 collaboration

Yun Liu 1 collaboration

Ting Ni 1 collaboration

Bo Wen 1 collaboration

Changqing Zeng 1 collaboration

Fan Liu 1 collaboration

Kirsten Seale 1 collaboration

Joseph M Raffaele 1 collaboration

Tavis L Mendez 1 collaboration

Yulu Chen 1 collaboration

Natalia Carreras 1 collaboration

Sofina Begum 1 collaboration

Kevin Mendez 1 collaboration

Sarah Voisin 1 collaboration

Nir Eynon 1 collaboration