Antimo Gioiello

Affiliations

Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.

Publications (29)

Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration.

Gastroenterology

Avec: Giovanni Sorrentino , Alessia Perino , Ece Yildiz , Gaby El Alam , Maroun Bou Sleiman , Antimo Gioiello , Roberto Pellicciari , Kristina Schoonjans

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor.

Journal of medicinal chemistry

Avec: Desirée Bartolini , Francesca De Franco , Pierangelo Torquato , Rita Marinelli , Bruno Cerra , Riccardo Ronchetti , Arne Schon , Francesca Fallarino , Antonella De Luca , Guido Bellezza , Ivana Ferri , Angelo Sidoni , William G Walton , Samuel J Pellock , Matthew R Redinbo , Sridhar Mani , Roberto Pellicciari , Antimo Gioiello , Francesco Galli

Garcinoic acid prevents β-amyloid (Aβ) deposition in the mouse brain.

The Journal of biological chemistry

Avec: Rita Marinelli , Pierangelo Torquato , Desirée Bartolini , Cristina Mas-Bargues , Guido Bellezza , Antimo Gioiello , Consuelo Borras , Antonella De Luca , Francesca Fallarino , Bartolomeo Sebastiani , Sridhar Mani , Angelo Sidoni , Jose Viña , Manuela Leri , Monica Bucciantini , Pamela Nardiello , Fiorella Casamenti , Francesco Galli

Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: M Marzano , Bruno Fosso , C Colliva , E Notario , D Passeri , M Intranuovo , A Gioiello , L Adorini , G Pesole , R Pellicciari , A Moschetta , R M Gadaleta

Identification and quantification of oxo-bile acids in human faeces with liquid chromatography-mass spectrometry: A potent tool for human gut acidic sterolbiome studies.

Journal of chromatography. A

Avec: P Franco , E Porru , J Fiori , A Gioiello , B Cerra , G Roda , C Caliceti , P Simoni , A Roda

Effect of a UV-C Automatic Last-Generation Mobile Robotic System on Multi-Drug Resistant Pathogens.

International journal of environmental research and public health

Avec: Carla Russo , Desirée Bartolini , Cristina Corbucci , Anna Maria Stabile , Mario Rende , Antimo Gioiello , Gabriele Cruciani , Antonella Mencacci , Francesco Galli , Donatella Pietrella

Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis.

RSC medicinal chemistry

Avec: Riccardo Ronchetti , Giada Moroni , Andrea Carotti , Antimo Gioiello , Emidio Camaioni

Patented farnesoid X receptor modulators: a review (2019 - present).

Expert opinion on therapeutic patents

Avec: Antimo Gioiello , Emiliano Rosatelli , Bruno Cerra

Enantioselective HPLC Analysis to Assist the Chemical Exploration of Chiral Imidazolines.

Molecules (Basel, Switzerland)

Avec: Bruno Cerra , Antonio Macchiarulo , Andrea Carotti , Emidio Camaioni , Ina Varfaj , Roccaldo Sardella , Antimo Gioiello

LC-MS/MS assay for the simultaneous determination of tocopherols, polyunsaturated fatty acids and their metabolites in human plasma and serum.

Free radical biology & medicine

Avec: Danilo Giusepponi , Roberta Galarini , Carolina Barola , Pierangelo Torquato , Desirée Bartolini , Simone Moretti , Giorgio Saluti , Antimo Gioiello , Carmelo Libetta , Francesco Galli

Endoplasmic reticulum stress and NF-kB activation in SARS-CoV-2 infected cells and their response to antiviral therapy.

IUBMB life

Avec: Desirée Bartolini , Anna Maria Stabile , Carmine Vacca , Alessandra Pistilli , Mario Rende , Antimo Gioiello , Gabriele Cruciani , Francesco Galli

How Aging and Oxidative Stress Influence the Cytopathic and Inflammatory Effects of SARS-CoV-2 Infection: The Role of Cellular Glutathione and Cysteine Metabolism.

Antioxidants (Basel, Switzerland)

Avec: Francesco Galli , Giada Marcantonini , Daniela Giustarini , Maria Cristina Albertini , Anna Migni , Linda Zatini , Antimo Gioiello , Ranieri Rossi , Desirée Bartolini

Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives.

Journal of chromatography. A

Avec: Federica Ianni , Bruno Cerra , Shiva Tali Shandiz , Alessandro Di Michele , Giorgio Saluti , Roberta Galarini , Antimo Gioiello , Roccaldo Sardella , Andrea Carotti

The Medicinal Chemistry in the Era of Machines and Automation: Recent Advances in Continuous Flow Technology.

Journal of medicinal chemistry

Avec: Antimo Gioiello , Alessandro Piccinno , Anna Maria Lozza , Bruno Cerra

D-leucine microparticles as an excipient to improve the aerosolization performances of dry powders for inhalation.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Avec: Aurélie Schoubben , Riccardo Vivani , Marco Paolantoni , Diego Romano Perinelli , Antimo Gioiello , Antonio Macchiarulo , Maurizio Ricci

Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists.

ACS medicinal chemistry letters

Avec: Bruno Cerra , Andrea Carotti , Daniela Passeri , Roccaldo Sardella , Giada Moroni , Alessandro Di Michele , Antonio Macchiarulo , Roberto Pellicciari , Antimo Gioiello

The Stone Guest: How Does pH Affect Binding Properties of PD-1/PD-L1 Inhibitors?

ChemMedChem

Avec: Alessandra Riccio , Alice Coletti , Daniela Dolciami , Andrea Mammoli , Bruno Cerra , Sonia Moretti , Antimo Gioiello , Simone Ferlin , Efisio Puxeddu , Antonio Macchiarulo

Development of 3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites.

European journal of medicinal chemistry

Avec: Bruno Cerra , Francesco Venturoni , Maria Souma , Giada Ceccarelli , Anna Maria Lozza , Daniela Passeri , Francesca De Franco , Ian R Baxendale , Roberto Pellicciari , Antonio Macchiarulo , Antimo Gioiello

Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency.

International journal of molecular sciences

Avec: Elisa Bianconi , Alessandra Riccio , Luana Ruta , Carlo Bigiotti , Andrea Carotti , Sonia Moretti , Bruno Cerra , Antimo Gioiello , Simone Ferlin , Efisio Puxeddu , Antonio Macchiarulo

Central anorexigenic actions of bile acids are mediated by TGR5.

Nature metabolism

Avec: Alessia Perino , Laura A Velázquez-Villegas , Nadia Bresciani , Yu Sun , Qingyao Huang , Valérie S Fénelon , Ashley Castellanos-Jankiewicz , Philippe Zizzari , Giuseppe Bruschetta , Sungho Jin , Aiste Baleisyte , Antimo Gioiello , Roberto Pellicciari , Julijana Ivanisevic , Bernard L Schneider , Sabrina Diano , Daniela Cota , Kristina Schoonjans

Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands.

Organic & biomolecular chemistry

Avec: Valentina Mancino , Giada Ceccarelli , Andrea Carotti , Laura Goracci , Roccaldo Sardella , Daniela Passeri , Roberto Pellicciari , Antimo Gioiello

Dissecting the allosteric FXR modulation: a chemical biology approach using guggulsterone as a chemical tool.

MedChemComm

Avec: Daniela Passeri , Andrea Carotti , Jose M Ramos Pittol , Gianmario Ciaccioli , Roberto Pellicciari , Saskia W C van Mil , Antimo Gioiello

Weak Microbial Metabolites: a Treasure Trove for Using Biomimicry to Discover and Optimize Drugs.

Molecular pharmacology

Avec: Zdenek Dvorak , Max Klapholz , Thomas P Burris , Benjamin P Willing , Antimo Gioiello , Roberto Pellicciari , Francesco Galli , John March , Stephen J O'Keefe , R Balfour Sartor , Chang H Kim , Maayan Levy , Sridhar Mani

SARS-CoV2 infection impairs the metabolism and redox function of cellular glutathione.

Redox biology

Avec: Desirée Bartolini , Anna Maria Stabile , Sabrina Bastianelli , Daniela Giustarini , Sara Pierucci , Chiara Busti , Carmine Vacca , Anna Gidari , Daniela Francisci , Roberto Castronari , Antonella Mencacci , Manlio Di Cristina , Riccardo Focaia , Samuele Sabbatini , Mario Rende , Antimo Gioiello , Gabriele Cruciani , Ranieri Rossi , Francesco Galli

Domino synthesis of 5-aminoimidazoles from Strecker multicomponent adducts via ytterbium-promoted isocyanide insertion/5-exo-dig cyclization.

Molecular diversity

Avec: Rolando Cannalire , Camilla Russo , Paolo Luciano , Bruno Cerra , Antimo Gioiello , Francesca Brunelli , Gian Cesare Tron , Mariateresa Giustiniano

Discovery and Structure-Activity Relationships of Novel

Journal of medicinal chemistry

Avec: Giada Ceccarelli , Laura Goracci , Andrea Carotti , Federico Paccoia , Daniela Passeri , Marco Cipolloni , Stefano Di Bona , Gabriele Cruciani , Roberto Pellicciari , Antimo Gioiello

Ratiometric Two-Photon Near-Infrared Probe to Detect DPP IV in Human Plasma, Living Cells, Human Tissues, and Whole Organisms Using Zebrafish.

ACS sensors

Avec: Javier Valverde-Pozo , Jose M Paredes , Thomas J Widmann , Carmen Griñan-Lison , Giada Ceccarelli , Antimo Gioiello , M Eugenia Garcia-Rubiño , Juan A Marchal , Jose M Alvarez-Pez , Eva M Talavera

Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives.

European journal of medicinal chemistry

Avec: Emiliano Rosatelli , Andrea Carotti , Bruno Cerra , Francesca De Franco , Daniela Passeri , Roberto Pellicciari , Antimo Gioiello

Multi-Gram Scale Synthesis and Characterization of Mometasone Furoate EP Impurity C.

Molecules (Basel, Switzerland)

Avec: Riccardo Ronchetti , Luigi Alfonso Pannone , Bruno Cerra , Emidio Camaioni , Gianfranco Lopopolo , Emanuele Attolino , Antimo Gioiello

Réseau de co-auteurs

Bruno Cerra 12 collaborations

Roberto Pellicciari 10 collaborations

Andrea Carotti 9 collaborations

Francesco Galli 8 collaborations

Desirée Bartolini 7 collaborations

Antonio Macchiarulo 6 collaborations

Daniela Passeri 6 collaborations

Gabriele Cruciani 4 collaborations

Roccaldo Sardella 4 collaborations

Giada Ceccarelli 4 collaborations

Francesca De Franco 3 collaborations

Pierangelo Torquato 3 collaborations

Riccardo Ronchetti 3 collaborations

Sridhar Mani 3 collaborations

Anna Maria Stabile 3 collaborations

Mario Rende 3 collaborations

Emidio Camaioni 3 collaborations

Alessia Perino 2 collaborations

Kristina Schoonjans 2 collaborations

Rita Marinelli 2 collaborations

Francesca Fallarino 2 collaborations

Antonella De Luca 2 collaborations

Guido Bellezza 2 collaborations

Angelo Sidoni 2 collaborations

A Gioiello 2 collaborations

Antonella Mencacci 2 collaborations

Giada Moroni 2 collaborations

Emiliano Rosatelli 2 collaborations

Roberta Galarini 2 collaborations

Giorgio Saluti 2 collaborations

Carmine Vacca 2 collaborations

Daniela Giustarini 2 collaborations

Ranieri Rossi 2 collaborations

Alessandro Di Michele 2 collaborations

Anna Maria Lozza 2 collaborations

Alessandra Riccio 2 collaborations

Sonia Moretti 2 collaborations

Simone Ferlin 2 collaborations

Efisio Puxeddu 2 collaborations

Laura Goracci 2 collaborations

Giovanni Sorrentino 1 collaboration

Ece Yildiz 1 collaboration

Gaby El Alam 1 collaboration

Maroun Bou Sleiman 1 collaboration

Arne Schon 1 collaboration

Ivana Ferri 1 collaboration

William G Walton 1 collaboration

Samuel J Pellock 1 collaboration

Matthew R Redinbo 1 collaboration

Cristina Mas-Bargues 1 collaboration

Consuelo Borras 1 collaboration

Bartolomeo Sebastiani 1 collaboration

Jose Viña 1 collaboration

Manuela Leri 1 collaboration

Monica Bucciantini 1 collaboration

Pamela Nardiello 1 collaboration

Fiorella Casamenti 1 collaboration

M Marzano 1 collaboration

Bruno Fosso 1 collaboration

C Colliva 1 collaboration

E Notario 1 collaboration

D Passeri 1 collaboration

M Intranuovo 1 collaboration

L Adorini 1 collaboration

G Pesole 1 collaboration

R Pellicciari 1 collaboration

A Moschetta 1 collaboration

R M Gadaleta 1 collaboration

P Franco 1 collaboration

E Porru 1 collaboration

J Fiori 1 collaboration

B Cerra 1 collaboration

G Roda 1 collaboration

C Caliceti 1 collaboration

P Simoni 1 collaboration

A Roda 1 collaboration

Carla Russo 1 collaboration

Cristina Corbucci 1 collaboration

Donatella Pietrella 1 collaboration

Ina Varfaj 1 collaboration

Danilo Giusepponi 1 collaboration

Carolina Barola 1 collaboration

Simone Moretti 1 collaboration

Carmelo Libetta 1 collaboration

Alessandra Pistilli 1 collaboration

Giada Marcantonini 1 collaboration

Maria Cristina Albertini 1 collaboration

Anna Migni 1 collaboration

Linda Zatini 1 collaboration

Federica Ianni 1 collaboration

Shiva Tali Shandiz 1 collaboration

Alessandro Piccinno 1 collaboration

Aurélie Schoubben 1 collaboration

Riccardo Vivani 1 collaboration

Marco Paolantoni 1 collaboration

Diego Romano Perinelli 1 collaboration

Maurizio Ricci 1 collaboration

Alice Coletti 1 collaboration

Daniela Dolciami 1 collaboration

Andrea Mammoli 1 collaboration

Francesco Venturoni 1 collaboration

Maria Souma 1 collaboration

Ian R Baxendale 1 collaboration

Elisa Bianconi 1 collaboration

Luana Ruta 1 collaboration

Carlo Bigiotti 1 collaboration

Laura A Velázquez-Villegas 1 collaboration

Nadia Bresciani 1 collaboration

Yu Sun 1 collaboration

Qingyao Huang 1 collaboration

Valérie S Fénelon 1 collaboration

Ashley Castellanos-Jankiewicz 1 collaboration

Philippe Zizzari 1 collaboration

Giuseppe Bruschetta 1 collaboration

Sungho Jin 1 collaboration

Aiste Baleisyte 1 collaboration

Julijana Ivanisevic 1 collaboration

Bernard L Schneider 1 collaboration

Sabrina Diano 1 collaboration

Daniela Cota 1 collaboration

Valentina Mancino 1 collaboration

Jose M Ramos Pittol 1 collaboration

Gianmario Ciaccioli 1 collaboration

Saskia W C van Mil 1 collaboration

Zdenek Dvorak 1 collaboration

Max Klapholz 1 collaboration

Thomas P Burris 1 collaboration

Benjamin P Willing 1 collaboration

John March 1 collaboration

Stephen J O'Keefe 1 collaboration

R Balfour Sartor 1 collaboration

Chang H Kim 1 collaboration

Maayan Levy 1 collaboration

Sabrina Bastianelli 1 collaboration

Sara Pierucci 1 collaboration

Chiara Busti 1 collaboration

Anna Gidari 1 collaboration

Daniela Francisci 1 collaboration

Roberto Castronari 1 collaboration

Manlio Di Cristina 1 collaboration

Riccardo Focaia 1 collaboration

Samuele Sabbatini 1 collaboration

Rolando Cannalire 1 collaboration

Camilla Russo 1 collaboration

Paolo Luciano 1 collaboration

Francesca Brunelli 1 collaboration

Gian Cesare Tron 1 collaboration

Mariateresa Giustiniano 1 collaboration

Federico Paccoia 1 collaboration

Marco Cipolloni 1 collaboration

Stefano Di Bona 1 collaboration

Javier Valverde-Pozo 1 collaboration

Jose M Paredes 1 collaboration

Thomas J Widmann 1 collaboration

Carmen Griñan-Lison 1 collaboration

M Eugenia Garcia-Rubiño 1 collaboration

Juan A Marchal 1 collaboration

Jose M Alvarez-Pez 1 collaboration

Eva M Talavera 1 collaboration

Luigi Alfonso Pannone 1 collaboration

Gianfranco Lopopolo 1 collaboration

Emanuele Attolino 1 collaboration