Benoit Larrat

Affiliations

NeuroSpin, CEA, Université Paris-Saclay, Gif-sur-Yvette, France.

Publications (35)

Targeting brain metastases with ultrasmall theranostic nanoparticles, a first-in-human trial from an MRI perspective.

Science advances

Avec: Camille Verry , Sandrine Dufort , Benjamin Lemasson , Sylvie Grand , Johan Pietras , Irène Troprès , Yannick Crémillieux , François Lux , Sébastien Mériaux , Benoit Larrat , Jacques Balosso , Géraldine Le Duc , Emmanuel L Barbier , Olivier Tillement

Planning Framework for Robot-assisted Blood-Brain Barrier Opening with Focused Ultrasound.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Avec: Gaelle Thomas , Laurent Barbe , Benoit Larrat , Pauline Agou , Jonathan Vappou , Florent Nageotte

Ultrasound-Mediated Blood-Brain Barrier Opening Improves Whole Brain Gene Delivery in Mice.

Pharmaceutics

Avec: Marie-Solenne Felix , Emilie Borloz , Khaled Metwally , Ambre Dauba , Benoit Larrat , Valerie Matagne , Yann Ehinger , Laurent Villard , Anthony Novell , Serge Mensah , Jean-Christophe Roux

Combination of thermal ablation by focused ultrasound, pFAR4-IL-12 transfection and lipidic adjuvant provide a distal immune response.

Exploration of targeted anti-tumor therapy

Avec: Hai Doan Do , Corinne Marie , Stéphanie Bessoles , Hélène Dhotel , Johanne Seguin , Benoit Larrat , Bich-Thuy Doan , Daniel Scherman , Virginie Escriou , Salima Hacein-Bey-Abina , Nathalie Mignet

Retinal functional ultrasound imaging (rfUS) for assessing neurovascular alterations: a pilot study on a rat model of dementia.

Scientific reports

Avec: Clementine Morisset , Alexandre Dizeux , Benoit Larrat , Erwan Selingue , Herve Boutin , Serge Picaud , Jose-Alain Sahel , Nathalie Ialy-Radio , Sophie Pezet , Mickael Tanter , Thomas Deffieux

CMUT for ultrafast passive cavitation detection during ultrasound-induced blood-brain barrier disruption: proof of concept study.

Physics in medicine and biology

Avec: Corentin Cornu , Laurène Jourdain , Flavien Barcella , Laurent Colin , Zoé Edon , Ambre Dauba , Erwan Selingue , Jean-Luc Gennisson , Benoit Larrat , Dominique Certon , Anthony Novell

Comparison between diffusion MRI tractography and histological tract-tracing of cortico-cortical structural connectivity in the ferret brain.

Network neuroscience (Cambridge, Mass.)

Avec: Céline Delettre , Arnaud Messé , Leigh-Anne Dell , Ophélie Foubet , Katja Heuer , Benoit Larrat , Sebastien Meriaux , Jean-Francois Mangin , Isabel Reillo , Camino de Juan Romero , Victor Borrell , Roberto Toro , Claus C Hilgetag

Wireless coils based on resonant and nonresonant coupled-wire structure for small animal multinuclear imaging.

NMR in biomedicine

Avec: Tania S Vergara Gomez , Marc Dubois , Stanislav Glybovski , Benoit Larrat , Julien de Rosny , Carsten Rockstuhl , Monique Bernard , Redha Abdeddaim , Stefan Enoch , Frank Kober

Simulation, Implementation and Measurement of Defined Sound Fields for Blood-Brain Barrier Opening in Rats.

Ultrasound in medicine & biology

Avec: Saskia Grudzenski , Stefan Heger , Andreas de Jonge , Julia Schipp , Erik Dumont , Benoit Larrat , Lothar Schad , Michael Platten , Marc Fatar

Molecular Imaging of Ultrasound-Mediated Blood-Brain Barrier Disruption in a Mouse Orthotopic Glioblastoma Model.

Pharmaceutics

Avec: Chiara Bastiancich , Samantha Fernandez , Florian Correard , Anthony Novell , Benoit Larrat , Benjamin Guillet , Marie-Anne Estève

Evaluation of capacitive micromachined ultrasonic transducers for passive monitoring of microbubble-assisted ultrasound therapies.

The Journal of the Acoustical Society of America

Avec: Ambre Dauba , Jordane Goulas , Laurent Colin , Laurène Jourdain , Benoit Larrat , Jean-Luc Gennisson , Dominique Certon , Anthony Novell

Recent Advances on Ultrasound Contrast Agents for Blood-Brain Barrier Opening with Focused Ultrasound.

Pharmaceutics

Avec: Ambre Dauba , Anthony Delalande , Hermes A S Kamimura , Allegra Conti , Benoit Larrat , Nicolas Tsapis , Anthony Novell

Refining the delivery and therapeutic efficacy of cetuximab using focused ultrasound in a mouse model of glioblastoma: An

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Avec: Estelle Porret , Dimitri Kereselidze , Ambre Dauba , Arnaud Schweitzer-Chaput , Benoit Jegot , Erwan Selingue , Nicolas Tournier , Benoît Larrat , Anthony Novell , Charles Truillet

Imaging the impact of blood-brain barrier disruption induced by focused ultrasound on P-glycoprotein function.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Sébastien Goutal , Anthony Novell , Sarah Leterrier , Louise Breuil , Erwan Selingue , Matthieu Gerstenmayer , Solène Marie , Bruno Saubaméa , Fabien Caillé , Oliver Langer , Charles Truillet , Benoît Larrat , Nicolas Tournier

Empirical and Theoretical Characterization of the Diffusion Process of Different Gadolinium-Based Nanoparticles within the Brain Tissue after Ultrasound-Induced Permeabilization of the Blood-Brain Barrier.

Contrast media & molecular imaging

Avec: Allegra Conti , Rémi Magnin , Matthieu Gerstenmayer , Nicolas Tsapis , Erik Dumont , Olivier Tillement , François Lux , Denis Le Bihan , Sébastien Mériaux , Stefania Della Penna , Benoit Larrat

Theranostic MRI liposomes for magnetic targeting and ultrasound triggered release of the antivascular CA4P.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Caroline J Thébault , Grégory Ramniceanu , Sarah Boumati , Aude Michel , Johanne Seguin , Benoit Larrat , Nathalie Mignet , Christine Ménager , Bich-Thuy Doan

AGuIX

The British journal of radiology

Avec: François Lux , Vu Long Tran , Eloïse Thomas , Sandrine Dufort , Fabien Rossetti , Matteo Martini , Charles Truillet , Tristan Doussineau , Guillaume Bort , Franck Denat , Frédéric Boschetti , Goran Angelovski , Alexandre Detappe , Yannick Crémillieux , Nathalie Mignet , Bich-Thuy Doan , Benoit Larrat , Sébastien Meriaux , Emmanuel Barbier , Stéphane Roux , Peter Fries , Andreas Müller , Marie-Caline Abadjian , Carolyn Anderson , Emmanuelle Canet-Soulas , Penelope Bouziotis , Muriel Barberi-Heyob , Céline Frochot , Camille Verry , Jacques Balosso , Michael Evans , Jacqueline Sidi-Boumedine , Marc Janier , Karl Butterworth , Stephen McMahon , Kevin Prise , Marie-Thérèse Aloy , Dominique Ardail , Claire Rodriguez-Lafrasse , Erika Porcel , Sandrine Lacombe , Ross Berbeco , Awatef Allouch , Jean-Luc Perfettini , Cyrus Chargari , Eric Deutsch , Géraldine Le Duc , Olivier Tillement

About the Marty model of blood-brain barrier closure after its disruption using focused ultrasound.

Physics in medicine and biology

Avec: Allegra Conti , Sébastien Mériaux , Benoit Larrat

Development of a multi-functional preclinical device for the treatment of glioblastoma.

Biomedical optics express

Avec: Khaled Metwally , Chiara Bastiancich , Florian Correard , Anthony Novell , Samantha Fernandez , Benjamin Guillet , Benoit Larrat , Serge Mensah , Marie-Anne Estève , Anabela Da Silva

Amphiphilic and Perfluorinated Poly(3-Hydroxyalkanoate) Nanocapsules for

Bioengineering (Basel, Switzerland)

Avec: Marion Le Gal , Estelle Renard , Christelle Simon-Colin , Benoit Larrat , Valérie Langlois

Regulation of P-glycoprotein and Breast Cancer Resistance Protein Expression Induced by Focused Ultrasound-Mediated Blood-Brain Barrier Disruption: A Pilot Study.

International journal of molecular sciences

Avec: Allegra Conti , Francoise Geffroy , Hermes A S Kamimura , Anthony Novell , Nicolas Tournier , Sébastien Mériaux , Benoit Larrat

New semi-analytical method for fast transcranial ultrasonic field simulation.

Physics in medicine and biology

Avec: Célestine Angla , Hamza Chouh , Paul Mondou , Gwenael Toullelan , Kévyn Perlin , Vincent Brulon , Emmanuel De Schlichting , Jean-Luc Gennisson , Benoit Larrat , Sylvain Chatillon

[

Annales pharmaceutiques francaises

Avec: Amélie Soyer , Sébastien Goutal , Sarah Leterrier , Solène Marie , Benoit Larrat , Erwan Selingue , Alexandra Winkeler , Marie Sarazin , Michel Bottlaender , Nicolas Tournier

Magnetic resonance cavitation imaging for the monitoring of ultrasound therapies.

Physics in medicine and biology

Avec: Ounay Ishak , Elodie Breton , Paolo Cabras , Erik Dumont , Paul Mondou , Anthony Novell , Benoit Larrat , Jonathan Vappou

Impact of blood-brain barrier permeabilization induced by ultrasound associated to microbubbles on the brain delivery and kinetics of cetuximab: An immunoPET study using

Journal of controlled release : official journal of the Controlled Release Society

Avec: Vu Long Tran , Anthony Novell , Nicolas Tournier , Matthieu Gerstenmayer , Arnaud Schweitzer-Chaput , Claudia Mateos , Benoit Jego , Alizée Bouleau , Hervé Nozach , Alexandra Winkeler , Bertrand Kuhnast , Benoit Larrat , Charles Truillet

A new safety index based on intrapulse monitoring of ultra-harmonic cavitation during ultrasound-induced blood-brain barrier opening procedures.

Scientific reports

Avec: A Novell , H A S Kamimura , A Cafarelli , M Gerstenmayer , J Flament , J Valette , P Agou , A Conti , E Selingue , R Aron Badin , P Hantraye , B Larrat

Feedback control of microbubble cavitation for ultrasound-mediated blood-brain barrier disruption in non-human primates under magnetic resonance guidance.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: Hermes As Kamimura , Julien Flament , Julien Valette , Andrea Cafarelli , Romina Aron Badin , Philippe Hantraye , Benoît Larrat

Laser- synthesized TiN nanoparticles as promising plasmonic alternative for biomedical applications.

Scientific reports

Avec: Anton A Popov , Gleb Tselikov , Noé Dumas , Charlotte Berard , Khaled Metwally , Nicola Jones , Ahmed Al-Kattan , Benoit Larrat , Diane Braguer , Serge Mensah , Anabela Da Silva , Marie-Anne Estève , Andrei V Kabashin

[

Pharmaceutics

Avec: Gaëlle Hugon , Sébastien Goutal , Ambre Dauba , Louise Breuil , Benoit Larrat , Alexandra Winkeler , Anthony Novell , Nicolas Tournier

Transcranial ultrasound simulations: A review.

Medical physics

Avec: Célestine Angla , Benoit Larrat , Jean-Luc Gennisson , Sylvain Chatillon

Perfluorocarbon Nanodroplets as Potential Nanocarriers for Brain Delivery Assisted by Focused Ultrasound-Mediated Blood-Brain Barrier Disruption.

Pharmaceutics

Avec: Charlotte Bérard , Stéphane Desgranges , Noé Dumas , Anthony Novell , Benoit Larrat , Mourad Hamimed , Nicolas Taulier , Marie-Anne Estève , Florian Correard , Christiane Contino-Pépin

Structural basis of envelope and phase intrinsic coupling modes in the cerebral cortex.

NeuroImage

Avec: Arnaud Messé , Karl J Hollensteiner , Céline Delettre , Leigh-Anne Dell-Brown , Florian Pieper , Lena J Nentwig , Edgar E Galindo-Leon , Benoît Larrat , Sébastien Mériaux , Jean-François Mangin , Isabel Reillo , Camino de Juan Romero , Víctor Borrell , Gerhard Engler , Roberto Toro , Andreas K Engel , Claus C Hilgetag

ImmunoPET imaging-based pharmacokinetic profiles of an antibody and its Fab targeting endothelin A receptors on glioblastoma stem cells in a preclinical orthotopic model.

European journal of nuclear medicine and molecular imaging

Avec: Marie Hautiere , Delphine Vivier , Donovan Pineau , Caroline Denis , Dimitri Kereselidze , Amaury Herbet , Narciso Costa , Victor Goncalves , Erwan Selingue , Benoit Larrat , Jean Philippe Hugnot , Franck Denat , Didier Boquet , Charles Truillet

Anticancer drug delivery by focused ultrasound-mediated blood-brain/tumor barrier disruption for glioma therapy: From benchside to bedside.

Pharmacology & therapeutics

Avec: Charlotte Bérard , Charles Truillet , Benoit Larrat , Frédéric Dhermain , Marie-Anne Estève , Florian Correard , Anthony Novell

State of the art on microbubble cavitation monitoring and feedback control for blood-brain-barrier opening using focused ultrasound.

Physics in medicine and biology

Avec: Paul Mondou , Sébastien Mériaux , Florent Nageotte , Jonathan Vappou , Anthony Novell , Benoit Larrat

Réseau de co-auteurs

Anthony Novell 15 collaborations

Sébastien Mériaux 6 collaborations

Ambre Dauba 6 collaborations

Erwan Selingue 6 collaborations

Nicolas Tournier 6 collaborations

Charles Truillet 6 collaborations

Marie-Anne Estève 5 collaborations

Jean-Luc Gennisson 4 collaborations

Florian Correard 4 collaborations

Allegra Conti 4 collaborations

Benoît Larrat 4 collaborations

François Lux 3 collaborations

Olivier Tillement 3 collaborations

Jonathan Vappou 3 collaborations

Khaled Metwally 3 collaborations

Serge Mensah 3 collaborations

Bich-Thuy Doan 3 collaborations

Nathalie Mignet 3 collaborations

Erik Dumont 3 collaborations

Sébastien Goutal 3 collaborations

Matthieu Gerstenmayer 3 collaborations

Paul Mondou 3 collaborations

Alexandra Winkeler 3 collaborations

Camille Verry 2 collaborations

Sandrine Dufort 2 collaborations

Yannick Crémillieux 2 collaborations

Jacques Balosso 2 collaborations

Géraldine Le Duc 2 collaborations

Florent Nageotte 2 collaborations

Johanne Seguin 2 collaborations

Laurène Jourdain 2 collaborations

Laurent Colin 2 collaborations

Dominique Certon 2 collaborations

Céline Delettre 2 collaborations

Arnaud Messé 2 collaborations

Isabel Reillo 2 collaborations

Camino de Juan Romero 2 collaborations

Roberto Toro 2 collaborations

Claus C Hilgetag 2 collaborations

Chiara Bastiancich 2 collaborations

Samantha Fernandez 2 collaborations

Benjamin Guillet 2 collaborations

Hermes A S Kamimura 2 collaborations

Nicolas Tsapis 2 collaborations

Dimitri Kereselidze 2 collaborations

Arnaud Schweitzer-Chaput 2 collaborations

Sarah Leterrier 2 collaborations

Louise Breuil 2 collaborations

Solène Marie 2 collaborations

Vu Long Tran 2 collaborations

Franck Denat 2 collaborations

Anabela Da Silva 2 collaborations

Célestine Angla 2 collaborations

Sylvain Chatillon 2 collaborations

Noé Dumas 2 collaborations

Charlotte Bérard 2 collaborations

Benjamin Lemasson 1 collaboration

Sylvie Grand 1 collaboration

Johan Pietras 1 collaboration

Irène Troprès 1 collaboration

Emmanuel L Barbier 1 collaboration

Gaelle Thomas 1 collaboration

Laurent Barbe 1 collaboration

Pauline Agou 1 collaboration

Marie-Solenne Felix 1 collaboration

Emilie Borloz 1 collaboration

Valerie Matagne 1 collaboration

Yann Ehinger 1 collaboration

Laurent Villard 1 collaboration

Jean-Christophe Roux 1 collaboration

Hai Doan Do 1 collaboration

Corinne Marie 1 collaboration

Stéphanie Bessoles 1 collaboration

Hélène Dhotel 1 collaboration

Daniel Scherman 1 collaboration

Virginie Escriou 1 collaboration

Salima Hacein-Bey-Abina 1 collaboration

Clementine Morisset 1 collaboration

Alexandre Dizeux 1 collaboration

Herve Boutin 1 collaboration

Serge Picaud 1 collaboration

Jose-Alain Sahel 1 collaboration

Nathalie Ialy-Radio 1 collaboration

Sophie Pezet 1 collaboration

Mickael Tanter 1 collaboration

Thomas Deffieux 1 collaboration

Corentin Cornu 1 collaboration

Flavien Barcella 1 collaboration

Zoé Edon 1 collaboration

Leigh-Anne Dell 1 collaboration

Ophélie Foubet 1 collaboration

Katja Heuer 1 collaboration

Sebastien Meriaux 1 collaboration

Jean-Francois Mangin 1 collaboration

Victor Borrell 1 collaboration

Tania S Vergara Gomez 1 collaboration

Marc Dubois 1 collaboration

Stanislav Glybovski 1 collaboration

Julien de Rosny 1 collaboration

Carsten Rockstuhl 1 collaboration

Monique Bernard 1 collaboration

Redha Abdeddaim 1 collaboration

Stefan Enoch 1 collaboration

Frank Kober 1 collaboration

Saskia Grudzenski 1 collaboration

Stefan Heger 1 collaboration

Andreas de Jonge 1 collaboration

Julia Schipp 1 collaboration

Lothar Schad 1 collaboration

Michael Platten 1 collaboration

Marc Fatar 1 collaboration

Jordane Goulas 1 collaboration

Anthony Delalande 1 collaboration

Estelle Porret 1 collaboration

Benoit Jegot 1 collaboration

Bruno Saubaméa 1 collaboration

Fabien Caillé 1 collaboration

Oliver Langer 1 collaboration

Rémi Magnin 1 collaboration

Denis Le Bihan 1 collaboration

Stefania Della Penna 1 collaboration

Caroline J Thébault 1 collaboration

Grégory Ramniceanu 1 collaboration

Sarah Boumati 1 collaboration

Aude Michel 1 collaboration

Christine Ménager 1 collaboration

Eloïse Thomas 1 collaboration

Fabien Rossetti 1 collaboration

Matteo Martini 1 collaboration

Tristan Doussineau 1 collaboration

Guillaume Bort 1 collaboration

Frédéric Boschetti 1 collaboration

Goran Angelovski 1 collaboration

Alexandre Detappe 1 collaboration

Sébastien Meriaux 1 collaboration

Emmanuel Barbier 1 collaboration

Stéphane Roux 1 collaboration

Peter Fries 1 collaboration

Andreas Müller 1 collaboration

Marie-Caline Abadjian 1 collaboration

Carolyn Anderson 1 collaboration

Emmanuelle Canet-Soulas 1 collaboration

Penelope Bouziotis 1 collaboration

Muriel Barberi-Heyob 1 collaboration

Céline Frochot 1 collaboration

Michael Evans 1 collaboration

Jacqueline Sidi-Boumedine 1 collaboration

Marc Janier 1 collaboration

Karl Butterworth 1 collaboration

Stephen McMahon 1 collaboration

Kevin Prise 1 collaboration

Marie-Thérèse Aloy 1 collaboration

Dominique Ardail 1 collaboration

Claire Rodriguez-Lafrasse 1 collaboration

Erika Porcel 1 collaboration

Sandrine Lacombe 1 collaboration

Ross Berbeco 1 collaboration

Awatef Allouch 1 collaboration

Jean-Luc Perfettini 1 collaboration

Cyrus Chargari 1 collaboration

Eric Deutsch 1 collaboration

Marion Le Gal 1 collaboration

Estelle Renard 1 collaboration

Christelle Simon-Colin 1 collaboration

Valérie Langlois 1 collaboration

Francoise Geffroy 1 collaboration

Hamza Chouh 1 collaboration

Gwenael Toullelan 1 collaboration

Kévyn Perlin 1 collaboration

Vincent Brulon 1 collaboration

Emmanuel De Schlichting 1 collaboration

Amélie Soyer 1 collaboration

Marie Sarazin 1 collaboration

Michel Bottlaender 1 collaboration

Ounay Ishak 1 collaboration

Elodie Breton 1 collaboration

Paolo Cabras 1 collaboration

Claudia Mateos 1 collaboration

Benoit Jego 1 collaboration

Alizée Bouleau 1 collaboration

Hervé Nozach 1 collaboration

Bertrand Kuhnast 1 collaboration

A Novell 1 collaboration

H A S Kamimura 1 collaboration

A Cafarelli 1 collaboration

M Gerstenmayer 1 collaboration

J Flament 1 collaboration

J Valette 1 collaboration

P Agou 1 collaboration

A Conti 1 collaboration

E Selingue 1 collaboration

R Aron Badin 1 collaboration

P Hantraye 1 collaboration

B Larrat 1 collaboration

Hermes As Kamimura 1 collaboration

Julien Flament 1 collaboration

Julien Valette 1 collaboration

Andrea Cafarelli 1 collaboration

Romina Aron Badin 1 collaboration

Philippe Hantraye 1 collaboration

Anton A Popov 1 collaboration

Gleb Tselikov 1 collaboration

Charlotte Berard 1 collaboration

Nicola Jones 1 collaboration

Ahmed Al-Kattan 1 collaboration

Diane Braguer 1 collaboration

Andrei V Kabashin 1 collaboration

Gaëlle Hugon 1 collaboration

Stéphane Desgranges 1 collaboration

Mourad Hamimed 1 collaboration

Nicolas Taulier 1 collaboration

Christiane Contino-Pépin 1 collaboration

Karl J Hollensteiner 1 collaboration

Leigh-Anne Dell-Brown 1 collaboration

Florian Pieper 1 collaboration

Lena J Nentwig 1 collaboration

Edgar E Galindo-Leon 1 collaboration

Jean-François Mangin 1 collaboration

Víctor Borrell 1 collaboration

Gerhard Engler 1 collaboration

Andreas K Engel 1 collaboration

Marie Hautiere 1 collaboration

Delphine Vivier 1 collaboration

Donovan Pineau 1 collaboration

Caroline Denis 1 collaboration

Amaury Herbet 1 collaboration

Narciso Costa 1 collaboration

Victor Goncalves 1 collaboration

Jean Philippe Hugnot 1 collaboration

Didier Boquet 1 collaboration

Frédéric Dhermain 1 collaboration