Brandon J DeKosky

Affiliations

Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS, USA. dekosky@ku.edu.
Department of Chemical Engineering, The University of Kansas, Lawrence, KS, USA. dekosky@ku.edu.
Bioengineering Graduate Program, The University of Kansas, Lawrence, KS, USA. dekosky@ku.edu.

ORCID: http://orcid.org/0000-0001-6406-0836

Publications (24)

Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies.

Nature microbiology

Avec: Wen Shi Lee , Adam K Wheatley , Stephen J Kent , Brandon J DeKosky

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.

Cell reports

Avec: Tongqing Zhou , I-Ting Teng , Adam S Olia , Gabriele Cerutti , Jason Gorman , Alexandra Nazzari , Wei Shi , Yaroslav Tsybovsky , Lingshu Wang , Shuishu Wang , Baoshan Zhang , Yi Zhang , Phinikoula S Katsamba , Yuliya Petrova , Bailey B Banach , Ahmed S Fahad , Lihong Liu , Sheila N Lopez Acevedo , Bharat Madan , Matheus Oliveira de Souza , Xiaoli Pan , Pengfei Wang , Jacy R Wolfe , Michael Yin , David D Ho , Emily Phung , Anthony DiPiazza , Lauren A Chang , Olubukola M Abiona , Kizzmekia S Corbett , Brandon J DeKosky , Barney S Graham , John R Mascola , John Misasi , Tracy Ruckwardt , Nancy J Sullivan , Lawrence Shapiro , Peter D Kwong

Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Bharat Madan , Baoshan Zhang , Kai Xu , Cara W Chao , Sijy O'Dell , Jacy R Wolfe , Gwo-Yu Chuang , Ahmed S Fahad , Hui Geng , Rui Kong , Mark K Louder , Thuy Duong Nguyen , Reda Rawi , Arne Schön , Zizhang Sheng , Rajani Nimrania , Yiran Wang , Tongqing Zhou , Bob C Lin , Nicole A Doria-Rose , Lawrence Shapiro , Peter D Kwong , Brandon J DeKosky

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.

Immunity

Avec: Maryam Mukhamedova , Daniel Wrapp , Chen-Hsiang Shen , Morgan S A Gilman , Tracy J Ruckwardt , Chaim A Schramm , Larissa Ault , Lauren Chang , Alexandrine Derrien-Colemyn , Sarah A M Lucas , Amy Ransier , Samuel Darko , Emily Phung , Lingshu Wang , Yi Zhang , Scott A Rush , Bharat Madan , Guillaume B E Stewart-Jones , Pamela J Costner , LaSonji A Holman , Somia P Hickman , Nina M Berkowitz , Nicole A Doria-Rose , Kaitlyn M Morabito , Brandon J DeKosky , Martin R Gaudinski , Grace L Chen , Michelle C Crank , John Misasi , Nancy J Sullivan , Daniel C Douek , Peter D Kwong , Barney S Graham , Jason S McLellan , John R Mascola

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.

bioRxiv : the preprint server for biology

Avec: Tongqing Zhou , I-Ting Teng , Adam S Olia , Gabriele Cerutti , Jason Gorman , Alexandra Nazzari , Wei Shi , Yaroslav Tsybovsky , Lingshu Wang , Shuishu Wang , Baoshan Zhang , Yi Zhang , Phinikoula S Katsamba , Yuliya Petrova , Bailey B Banach , Ahmed S Fahad , Lihong Liu , Sheila N Lopez Acevedo , Bharat Madan , Matheus Oliveira de Souza , Xiaoli Pan , Pengfei Wang , Jacy R Wolfe , Michael Yin , David D Ho , Emily Phung , Anthony DiPiazza , Lauren Chang , Olubukula Abiona , Kizzmekia S Corbett , Brandon J DeKosky , Barney S Graham , John R Mascola , John Misasi , Tracy Ruckwardt , Nancy J Sullivan , Lawrence Shapiro , Peter D Kwong

Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.

Frontiers in immunology

Avec: Gwo-Yu Chuang , Chen-Hsiang Shen , Crystal Sao-Fong Cheung , Jason Gorman , Adrian Creanga , M Gordon Joyce , Kwanyee Leung , Reda Rawi , Lingshu Wang , Eun Sung Yang , Yongping Yang , Baoshan Zhang , Yi Zhang , Masaru Kanekiyo , Tongqing Zhou , Brandon J DeKosky , Barney S Graham , John R Mascola , Peter D Kwong

Molecular probes of spike ectodomain and its subdomains for SARS-CoV-2 variants, Alpha through Omicron.

bioRxiv : the preprint server for biology

Avec: I-Ting Teng , Alexandra F Nazzari , Misook Choe , Tracy Liu , Matheus Oliveira de Souza , Yuliya Petrova , Yaroslav Tsybovsky , Shuishu Wang , Baoshan Zhang , Mykhaylo Artamonov , Bharat Madan , Aric Huang , Sheila N Lopez Acevedo , Xiaoli Pan , Tracy J Ruckwardt , Brandon J DeKosky , John R Mascola , John Misasi , Nancy J Sullivan , Tongqing Zhou , Peter D Kwong

Optimized Production of Fc Fusion Proteins by Sortase Enzymatic Ligation.

Industrial & engineering chemistry research

Avec: Kyle D Apley , Amy D Laflin , Stephanie N Johnson , Noora Batrash , J Daniel Griffin , Cory J Berkland , Brandon J DeKosky

Antibody-guided structure-based vaccines.

Seminars in immunology

Avec: Peter D Kwong , Brandon J DeKosky , Jeffrey B Ulmer

Multimeric Insulin Desensitizes Insulin-Specific B Cells.

ACS applied bio materials

Avec: Stephanie N Johnson , J Daniel Griffin , Chrys Hulbert , Brandon J DeKosky , James W Thomas , Cory J Berkland

Highly protective antimalarial antibodies via precision library generation and yeast display screening.

The Journal of experimental medicine

Avec: Bailey B Banach , Prabhanshu Tripathi , Lais Da Silva Pereira , Jason Gorman , Thuy Duong Nguyen , Marlon Dillon , Ahmed S Fahad , Patience K Kiyuka , Bharat Madan , Jacy R Wolfe , Brian Bonilla , Barbara Flynn , Joseph R Francica , Nicholas K Hurlburt , Neville K Kisalu , Tracy Liu , Li Ou , Reda Rawi , Arne Schön , Chen-Hsiang Shen , I-Ting Teng , Baoshan Zhang , Marie Pancera , Azza H Idris , Robert A Seder , Peter D Kwong , Brandon J DeKosky

Cell activation-based screening of natively paired human T cell receptor repertoires.

Scientific reports

Avec: Ahmed S Fahad , Cheng Yu Chung , Sheila N López Acevedo , Nicoleen Boyle , Bharat Madan , Matías F Gutiérrez-González , Rodrigo Matus-Nicodemos , Amy D Laflin , Rukmini R Ladi , John Zhou , Jacy Wolfe , Sian Llewellyn-Lacey , Richard A Koup , Daniel C Douek , Henry H Balfour , David A Price , Brandon J DeKosky

Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.

Nature communications

Avec: Bailey B Banach , Sergei Pletnev , Adam S Olia , Kai Xu , Baoshan Zhang , Reda Rawi , Tatsiana Bylund , Nicole A Doria-Rose , Thuy Duong Nguyen , Ahmed S Fahad , Myungjin Lee , Bob C Lin , Tracy Liu , Mark K Louder , Bharat Madan , Krisha McKee , Sijy O'Dell , Mallika Sastry , Arne Schön , Natalie Bui , Chen-Hsiang Shen , Jacy R Wolfe , Gwo-Yu Chuang , John R Mascola , Peter D Kwong , Brandon J DeKosky

Linking autoantigen properties to mechanisms of immunity.

Advanced drug delivery reviews

Avec: J Daniel Griffin , Jimmy Y Song , Joshua O Sestak , Brandon J DeKosky , Cory J Berkland

The covalent SNAP tag for protein display quantification and low-pH protein engineering.

Journal of biotechnology

Avec: Wei Jin , Bharat Madan , Brooklyn K Mussman , Amen T Hailemariam , Ahmed S Fahad , Jacy R Wolfe , Young Do Kwon , Baoshan Zhang , Lawrence Shapiro , Peter D Kwong , Brandon J DeKosky

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes.

SSRN

Avec: Tongqing Zhou , I-Ting Teng , Adam S Olia , Gabriele Cerutti , Jason Gorman , Alexandra Nazzari , Wei Shi , Yaroslav Tsybovsky , Lingshu Wang , Shuishu Wang , Baoshan Zhang , Yi Zhang , Phinikoula S Katsamba , Yuliya Petrova , Bailey B Banach , Ahmed S Fahad , Lihong Liu , Sheila N Lopez Acevedo , Bharat Madan , Matheus Olivera de Souza , Xiaoli Pan , Pengfei Wang , Jacy R Wolfe , Michael Yin , David D Ho , Emily Phung , Anthony DiPiazza , Lauren Chang , Olubukula Abiona , Kizzmekia S Corbett , Brandon J DeKosky , Barney S Graham , John R Mascola , John Misasi , Tracy Ruckwardt , Nancy J Sullivan , Lawrence Shapiro , Peter D Kwong

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.

Cell reports

Avec: Bailey B Banach , Gabriele Cerutti , Ahmed S Fahad , Chen-Hsiang Shen , Matheus Oliveira De Souza , Phinikoula S Katsamba , Yaroslav Tsybovsky , Pengfei Wang , Manoj S Nair , Yaoxing Huang , Irene M Francino-Urdániz , Paul J Steiner , Matías Gutiérrez-González , Lihong Liu , Sheila N López Acevedo , Alexandra F Nazzari , Jacy R Wolfe , Yang Luo , Adam S Olia , I-Ting Teng , Jian Yu , Tongqing Zhou , Eswar R Reddem , Jude Bimela , Xiaoli Pan , Bharat Madan , Amy D Laflin , Rajani Nimrania , Kwok-Yung Yuen , Timothy A Whitehead , David D Ho , Peter D Kwong , Lawrence Shapiro , Brandon J DeKosky

Tetrameric Fluorescent Antigen Arrays for Single-Step Identification of Antigen-Specific B Cells.

Journal of visualized experiments : JoVE

Avec: Kyle D Apley , J Daniel Griffin , Stephanie N Johnson , Cory J Berkland , Brandon J DeKosky

Immortalization and functional screening of natively paired human T cell receptor repertoires.

Protein engineering, design & selection : PEDS

Avec: Ahmed S Fahad , Cheng-Yu Chung , Sheila N Lopez Acevedo , Nicoleen Boyle , Bharat Madan , Matias F Gutiérrez-González , Rodrigo Matus-Nicodemos , Amy D Laflin , Rukmini R Ladi , John Zhou , Jacy Wolfe , Sian Llewellyn-Lacey , Richard A Koup , Daniel C Douek , Henry H Balfour , David A Price , Brandon J DeKosky

Strategies to Screen Anti-AQP4 Antibodies from Yeast Surface Display Libraries.

Antibodies (Basel, Switzerland)

Avec: Aric Huang , Wei Jin , Ahmed S Fahad , Brooklyn K Mussman , Grazia Paola Nicchia , Bharat Madan , Matheus Oliveira de Souza , J Daniel Griffin , Jeffrey L Bennett , Antonio Frigeri , Cory J Berkland , Brandon J DeKosky

Bioinformatic Analysis of Natively Paired VH:VL Antibody Repertoires for Antibody Discovery.

Methods in molecular biology (Clifton, N.J.)

Avec: Ahmed S Fahad , Bharat Madan , Brandon J DeKosky

Large-scale antibody immune response mapping of splenic B cells and bone marrow plasma cells in a transgenic mouse model.

Frontiers in immunology

Avec: Xiaoli Pan , Sheila N López Acevedo , Camille Cuziol , Evelyn De Tavernier , Ahmed S Fahad , Priyobarta S Longjam , Sambasiva P Rao , David Aguilera-Rodríguez , Mathilde Rezé , Christine A Bricault , Matías F Gutiérrez-González , Matheus Oliveira de Souza , Joshua M DiNapoli , Emmanuelle Vigne , Melody A Shahsavarian , Brandon J DeKosky

Human intratumoral therapy: Linking drug properties and tumor transport of drugs in clinical trials.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Aric Huang , Melissa M Pressnall , Ruolin Lu , Sebastian G Huayamares , J Daniel Griffin , Chad Groer , Brandon J DeKosky , M Laird Forrest , Cory J Berkland

Ultrasonically-guided flow focusing generates precise emulsion droplets for high-throughput single cell analyses.

Journal of bioscience and bioengineering

Avec: Colton E Lagerman , Sheila N López Acevedo , Ahmed S Fahad , Amen T Hailemariam , Bharat Madan , Brandon J DeKosky

Réseau de co-auteurs

Bharat Madan 15 collaborations

Ahmed S Fahad 14 collaborations

Peter D Kwong 12 collaborations

Baoshan Zhang 9 collaborations

Jacy R Wolfe 8 collaborations

Tongqing Zhou 7 collaborations

John R Mascola 7 collaborations

I-Ting Teng 6 collaborations

Bailey B Banach 6 collaborations

Xiaoli Pan 6 collaborations

Lawrence Shapiro 6 collaborations

J Daniel Griffin 6 collaborations

Cory J Berkland 6 collaborations

Adam S Olia 5 collaborations

Jason Gorman 5 collaborations

Yaroslav Tsybovsky 5 collaborations

Lingshu Wang 5 collaborations

Yi Zhang 5 collaborations

Sheila N Lopez Acevedo 5 collaborations

Matheus Oliveira de Souza 5 collaborations

Barney S Graham 5 collaborations

John Misasi 5 collaborations

Nancy J Sullivan 5 collaborations

Chen-Hsiang Shen 5 collaborations

Gabriele Cerutti 4 collaborations

Shuishu Wang 4 collaborations

Phinikoula S Katsamba 4 collaborations

Yuliya Petrova 4 collaborations

Lihong Liu 4 collaborations

Pengfei Wang 4 collaborations

David D Ho 4 collaborations

Emily Phung 4 collaborations

Reda Rawi 4 collaborations

Amy D Laflin 4 collaborations

Sheila N López Acevedo 4 collaborations

Alexandra Nazzari 3 collaborations

Wei Shi 3 collaborations

Michael Yin 3 collaborations

Anthony DiPiazza 3 collaborations

Kizzmekia S Corbett 3 collaborations

Tracy Ruckwardt 3 collaborations

Gwo-Yu Chuang 3 collaborations

Thuy Duong Nguyen 3 collaborations

Arne Schön 3 collaborations

Nicole A Doria-Rose 3 collaborations

Lauren Chang 3 collaborations

Daniel C Douek 3 collaborations

Tracy Liu 3 collaborations

Aric Huang 3 collaborations

Stephanie N Johnson 3 collaborations

Kai Xu 2 collaborations

Sijy O'Dell 2 collaborations

Mark K Louder 2 collaborations

Rajani Nimrania 2 collaborations

Bob C Lin 2 collaborations

Tracy J Ruckwardt 2 collaborations

Olubukula Abiona 2 collaborations

Alexandra F Nazzari 2 collaborations

Kyle D Apley 2 collaborations

Nicoleen Boyle 2 collaborations

Matías F Gutiérrez-González 2 collaborations

Rodrigo Matus-Nicodemos 2 collaborations

Rukmini R Ladi 2 collaborations

John Zhou 2 collaborations

Jacy Wolfe 2 collaborations

Sian Llewellyn-Lacey 2 collaborations

Richard A Koup 2 collaborations

Henry H Balfour 2 collaborations

David A Price 2 collaborations

Wei Jin 2 collaborations

Brooklyn K Mussman 2 collaborations

Amen T Hailemariam 2 collaborations

Wen Shi Lee 1 collaboration

Adam K Wheatley 1 collaboration

Stephen J Kent 1 collaboration

Lauren A Chang 1 collaboration

Olubukola M Abiona 1 collaboration

Cara W Chao 1 collaboration

Hui Geng 1 collaboration

Rui Kong 1 collaboration

Zizhang Sheng 1 collaboration

Yiran Wang 1 collaboration

Maryam Mukhamedova 1 collaboration

Daniel Wrapp 1 collaboration

Morgan S A Gilman 1 collaboration

Chaim A Schramm 1 collaboration

Larissa Ault 1 collaboration

Alexandrine Derrien-Colemyn 1 collaboration

Sarah A M Lucas 1 collaboration

Amy Ransier 1 collaboration

Samuel Darko 1 collaboration

Scott A Rush 1 collaboration

Guillaume B E Stewart-Jones 1 collaboration

Pamela J Costner 1 collaboration

LaSonji A Holman 1 collaboration

Somia P Hickman 1 collaboration

Nina M Berkowitz 1 collaboration

Kaitlyn M Morabito 1 collaboration

Martin R Gaudinski 1 collaboration

Grace L Chen 1 collaboration

Michelle C Crank 1 collaboration

Jason S McLellan 1 collaboration

Crystal Sao-Fong Cheung 1 collaboration

Adrian Creanga 1 collaboration

M Gordon Joyce 1 collaboration

Kwanyee Leung 1 collaboration

Eun Sung Yang 1 collaboration

Yongping Yang 1 collaboration

Masaru Kanekiyo 1 collaboration

Misook Choe 1 collaboration

Mykhaylo Artamonov 1 collaboration

Noora Batrash 1 collaboration

Jeffrey B Ulmer 1 collaboration

Chrys Hulbert 1 collaboration

James W Thomas 1 collaboration

Prabhanshu Tripathi 1 collaboration

Lais Da Silva Pereira 1 collaboration

Marlon Dillon 1 collaboration

Patience K Kiyuka 1 collaboration

Brian Bonilla 1 collaboration

Barbara Flynn 1 collaboration

Joseph R Francica 1 collaboration

Nicholas K Hurlburt 1 collaboration

Neville K Kisalu 1 collaboration

Li Ou 1 collaboration

Marie Pancera 1 collaboration

Azza H Idris 1 collaboration

Robert A Seder 1 collaboration

Cheng Yu Chung 1 collaboration

Sergei Pletnev 1 collaboration

Tatsiana Bylund 1 collaboration

Myungjin Lee 1 collaboration

Krisha McKee 1 collaboration

Mallika Sastry 1 collaboration

Natalie Bui 1 collaboration

Jimmy Y Song 1 collaboration

Joshua O Sestak 1 collaboration

Young Do Kwon 1 collaboration

Matheus Olivera de Souza 1 collaboration

Matheus Oliveira De Souza 1 collaboration

Manoj S Nair 1 collaboration

Yaoxing Huang 1 collaboration

Irene M Francino-Urdániz 1 collaboration

Paul J Steiner 1 collaboration

Matías Gutiérrez-González 1 collaboration

Yang Luo 1 collaboration

Jian Yu 1 collaboration

Eswar R Reddem 1 collaboration

Jude Bimela 1 collaboration

Kwok-Yung Yuen 1 collaboration

Timothy A Whitehead 1 collaboration

Cheng-Yu Chung 1 collaboration

Matias F Gutiérrez-González 1 collaboration

Grazia Paola Nicchia 1 collaboration

Jeffrey L Bennett 1 collaboration

Antonio Frigeri 1 collaboration

Camille Cuziol 1 collaboration

Evelyn De Tavernier 1 collaboration

Priyobarta S Longjam 1 collaboration

Sambasiva P Rao 1 collaboration

David Aguilera-Rodríguez 1 collaboration

Mathilde Rezé 1 collaboration

Christine A Bricault 1 collaboration

Joshua M DiNapoli 1 collaboration

Emmanuelle Vigne 1 collaboration

Melody A Shahsavarian 1 collaboration

Melissa M Pressnall 1 collaboration

Ruolin Lu 1 collaboration

Sebastian G Huayamares 1 collaboration

Chad Groer 1 collaboration

M Laird Forrest 1 collaboration

Colton E Lagerman 1 collaboration