Daniel Wrapp

Affiliations

Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.

Publications (47)

Cryo-EM Structure of the 2019-nCoV Spike in the Prefusion Conformation.

bioRxiv : the preprint server for biology

Avec: Daniel Wrapp , Nianshuang Wang , Kizzmekia S Corbett , Jory A Goldsmith , Ching-Lin Hsieh , Olubukola Abiona , Barney S Graham , Jason S McLellan

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

Science (New York, N.Y.)

Avec: Daniel Wrapp , Nianshuang Wang , Kizzmekia S Corbett , Jory A Goldsmith , Ching-Lin Hsieh , Olubukola Abiona , Barney S Graham , Jason S McLellan

A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants.

mBio

Avec: Denise Haslwanter , M Eugenia Dieterle , Anna Z Wec , Cecilia M O'Brien , Mrunal Sakharkar , Catalina Florez , Karen Tong , C Garrett Rappazzo , Gorka Lasso , Olivia Vergnolle , Ariel S Wirchnianski , Robert H Bortz , Ethan Laudermilch , J Maximilian Fels , Amanda Mengotto , Ryan J Malonis , George I Georgiev , Jose A Quiroz , Daniel Wrapp , Nianshuang Wang , Kathryn E Dye , Jason Barnhill , John M Dye , Jason S McLellan , Johanna P Daily , Jonathan R Lai , Andrew S Herbert , Laura M Walker , Kartik Chandran , Rohit K Jangra

Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.

Nature communications

Avec: A Brenda Kapingidza , Daniel J Marston , Caitlin Harris , Daniel Wrapp , Kaitlyn Winters , Dieter Mielke , Lu Xiaozhi , Qi Yin , Andrew Foulger , Rob Parks , Maggie Barr , Amanda Newman , Alexandra Schäfer , Amanda Eaton , Justine Mae Flores , Austin Harner , Nicholas J Catanzaro , Michael L Mallory , Melissa D Mattocks , Christopher Beverly , Brianna Rhodes , Katayoun Mansouri , Elizabeth Van Itallie , Pranay Vure , Brooke Dunn , Taylor Keyes , Sherry Stanfield-Oakley , Christopher W Woods , Elizabeth A Petzold , Emmanuel B Walter , Kevin Wiehe , Robert J Edwards , David C Montefiori , Guido Ferrari , Ralph Baric , Derek W Cain , Kevin O Saunders , Barton F Haynes , Mihai L Azoitei

Site-specific glycan analysis of the SARS-CoV-2 spike.

Science (New York, N.Y.)

Avec: Yasunori Watanabe , Joel D Allen , Daniel Wrapp , Jason S McLellan , Max Crispin

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein.

bioRxiv : the preprint server for biology

Avec: Anna Z Wec , Daniel Wrapp , Andrew S Herbert , Daniel Maurer , Denise Haslwanter , Mrunal Sakharkar , Rohit K Jangra , M Eugenia Dieterle , Asparouh Lilov , Deli Huang , Longping V Tse , Nicole V Johnson , Ching-Lin Hsieh , Nianshuang Wang , Juergen H Nett , Elizabeth Champney , Irina Burnina , Michael Brown , Shu Lin , Melanie Sinclair , Carl Johnson , Sarat Pudi , Robert Bortz , Ariel S Wirchnianski , Ethan Laudermilch , Catalina Florez , J Maximilian Fels , Cecilia M O'Brien , Barney S Graham , David Nemazee , Dennis R Burton , Ralph S Baric , James E Voss , Kartik Chandran , John M Dye , Jason S McLellan , Laura M Walker

Broad neutralization of SARS-related viruses by human monoclonal antibodies.

Science (New York, N.Y.)

Avec: Anna Z Wec , Daniel Wrapp , Andrew S Herbert , Daniel P Maurer , Denise Haslwanter , Mrunal Sakharkar , Rohit K Jangra , M Eugenia Dieterle , Asparouh Lilov , Deli Huang , Longping V Tse , Nicole V Johnson , Ching-Lin Hsieh , Nianshuang Wang , Juergen H Nett , Elizabeth Champney , Irina Burnina , Michael Brown , Shu Lin , Melanie Sinclair , Carl Johnson , Sarat Pudi , Robert Bortz , Ariel S Wirchnianski , Ethan Laudermilch , Catalina Florez , J Maximilian Fels , Cecilia M O'Brien , Barney S Graham , David Nemazee , Dennis R Burton , Ralph S Baric , James E Voss , Kartik Chandran , John M Dye , Jason S McLellan , Laura M Walker

Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape.

Nature communications

Avec: Zhiqiang Ku , Xuping Xie , Edgar Davidson , Xiaohua Ye , Hang Su , Vineet D Menachery , Yize Li , Zihao Yuan , Xianwen Zhang , Antonio E Muruato , Ariadna Grinyo I Escuer , Breanna Tyrell , Kyle Doolan , Benjamin J Doranz , Daniel Wrapp , Paul F Bates , Jason S McLellan , Susan R Weiss , Ningyan Zhang , Pei-Yong Shi , Zhiqiang An

Efficient discovery of SARS-CoV-2-neutralizing antibodies via B cell receptor sequencing and ligand blocking.

Nature biotechnology

Avec: Andrea R Shiakolas , Kevin J Kramer , Nicole V Johnson , Steven C Wall , Naveenchandra Suryadevara , Daniel Wrapp , Sivakumar Periasamy , Kelsey A Pilewski , Nagarajan Raju , Rachel Nargi , Rachel E Sutton , Lauren M Walker , Ian Setliff , James E Crowe , Alexander Bukreyev , Robert H Carnahan , Jason S McLellan , Ivelin S Georgiev

Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive protection across divergent subgroups.

Research square

Avec: Geoffrey Hutchinson , Olubukola Abiona , Cynthia Ziwawo , Anne Werner , Daniel Ellis , Yaroslav Tsybovsky , Sarah Leist , Charis Palandjian , Ande West , Ethan Fritch , Niangshuang Wang , Daniel Wrapp , Seyhan Boyoglu-Barnum , George Ueda , David Baker , Masaru Kanekiyo , Jason McLellan , Ralph Baric , Neil King , Barney Graham , Kizzmekia Corbett

Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera.

Nature communications

Avec: Geoffrey B Hutchinson , Olubukola M Abiona , Cynthia T Ziwawo , Anne P Werner , Daniel Ellis , Yaroslav Tsybovsky , Sarah R Leist , Charis Palandjian , Ande West , Ethan J Fritch , Nianshuang Wang , Daniel Wrapp , Seyhan Boyoglu-Barnum , George Ueda , David Baker , Masaru Kanekiyo , Jason S McLellan , Ralph S Baric , Neil P King , Barney S Graham , Kizzmekia S Corbett-Helaire

A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus.

PLoS pathogens

Avec: Jennifer A Jenks , Sharmi Amin , Madeline R Sponholtz , Amit Kumar , Daniel Wrapp , Sravani Venkatayogi , Joshua J Tu , Krithika Karthigeyan , Sarah M Valencia , Megan Connors , Melissa J Harnois , Bhavna Hora , Eric Rochat , Jason S McLellan , Kevin Wiehe , Sallie R Permar

Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures.

IUCrJ

Avec: Roberto Melero , Carlos Oscar S Sorzano , Brent Foster , José-Luis Vilas , Marta Martínez , Roberto Marabini , Erney Ramírez-Aportela , Ruben Sanchez-Garcia , David Herreros , Laura Del Caño , Patricia Losana , Yunior C Fonseca-Reyna , Pablo Conesa , Daniel Wrapp , Pablo Chacon , Jason S McLellan , Hemant D Tagare , Jose-Maria Carazo

Structural basis for assembly of non-canonical small subunits into type I-C Cascade.

Nature communications

Avec: Roisin E O'Brien , Inês C Santos , Daniel Wrapp , Jack P K Bravo , Evan A Schwartz , Jennifer S Brodbelt , David W Taylor

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.

Nature

Avec: Kizzmekia S Corbett , Darin K Edwards , Sarah R Leist , Olubukola M Abiona , Seyhan Boyoglu-Barnum , Rebecca A Gillespie , Sunny Himansu , Alexandra Schäfer , Cynthia T Ziwawo , Anthony T DiPiazza , Kenneth H Dinnon , Sayda M Elbashir , Christine A Shaw , Angela Woods , Ethan J Fritch , David R Martinez , Kevin W Bock , Mahnaz Minai , Bianca M Nagata , Geoffrey B Hutchinson , Kai Wu , Carole Henry , Kapil Bahl , Dario Garcia-Dominguez , LingZhi Ma , Isabella Renzi , Wing-Pui Kong , Stephen D Schmidt , Lingshu Wang , Yi Zhang , Emily Phung , Lauren A Chang , Rebecca J Loomis , Nedim Emil Altaras , Elisabeth Narayanan , Mihir Metkar , Vlad Presnyak , Cuiping Liu , Mark K Louder , Wei Shi , Kwanyee Leung , Eun Sung Yang , Ande West , Kendra L Gully , Laura J Stevens , Nianshuang Wang , Daniel Wrapp , Nicole A Doria-Rose , Guillaume Stewart-Jones , Hamilton Bennett , Gabriela S Alvarado , Martha C Nason , Tracy J Ruckwardt , Jason S McLellan , Mark R Denison , James D Chappell , Ian N Moore , Kaitlyn M Morabito , John R Mascola , Ralph S Baric , Andrea Carfi , Barney S Graham

Structure-based Design of Prefusion-stabilized SARS-CoV-2 Spikes.

bioRxiv : the preprint server for biology

Avec: Ching-Lin Hsieh , Jory A Goldsmith , Jeffrey M Schaub , Andrea M DiVenere , Hung-Che Kuo , Kamyab Javanmardi , Kevin C Le , Daniel Wrapp , Alison Gene-Wei Lee , Yutong Liu , Chia-Wei Chou , Patrick O Byrne , Christy K Hjorth , Nicole V Johnson , John Ludes-Meyers , Annalee W Nguyen , Juyeon Park , Nianshuang Wang , Dzifa Amengor , Jennifer A Maynard , Ilya J Finkelstein , Jason S McLellan

Site-specific analysis of the SARS-CoV-2 glycan shield.

bioRxiv : the preprint server for biology

Avec: Yasunori Watanabe , Joel D Allen , Daniel Wrapp , Jason S McLellan , Max Crispin

Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking.

bioRxiv : the preprint server for biology

Avec: Andrea R Shiakolas , Nicole Johnson , Kevin J Kramer , Naveenchandra Suryadevara , Daniel Wrapp , Sivakumar Periasamy , Kelsey A Pilewski , Nagarajan Raju , Rachel Nargi , Rachel E Sutton , Lauren Walker , Ian Setliff , James E Crowe , Alexander Bukreyev , Robert H Carnahan , Jason S McLellan , Ivelin S Georgiev

Expression and characterization of SARS-CoV-2 spike proteins.

Nature protocols

Avec: Jeffrey M Schaub , Chia-Wei Chou , Hung-Che Kuo , Kamyab Javanmardi , Ching-Lin Hsieh , Jory Goldsmith , Andrea M DiVenere , Kevin C Le , Daniel Wrapp , Patrick O Byrne , Christy K Hjorth , Nicole V Johnson , John Ludes-Meyers , Annalee W Nguyen , Nianshuang Wang , Jason J Lavinder , Gregory C Ippolito , Jennifer A Maynard , Jason S McLellan , Ilya J Finkelstein

Structural rearrangements allow nucleic acid discrimination by type I-D Cascade.

Nature communications

Avec: Evan A Schwartz , Tess M McBride , Jack P K Bravo , Daniel Wrapp , Peter C Fineran , Robert D Fagerlund , David W Taylor

Engineered Immunogens to Elicit Antibodies Against Conserved Coronavirus Epitopes.

bioRxiv : the preprint server for biology

Avec: Brenda Kapingidza , Daniel J Marston , Caitlin Harris , Daniel Wrapp , Kaitlyn Winters , Dieter Mielke , Lu Xiaozhi , Qi Yin , Andrew Foulger , Rob Parks , Maggie Barr , Amanda Newman , Alexandra Schäfer , Amanda Eaton , Justine Mae Flores , Austin Harner , Nicholas J Cantazaro , Michael L Mallory , Melissa D Mattocks , Christopher Beverly , Brianna Rhodes , Katayoun Mansouri , Elizabeth Van Itallie , Pranay Vure , Brooke Manness , Taylor Keyes , Sherry Stanfield-Oakley , Christopher W Woods , Elizabeth A Petzold , Emmanuel B Walter , Kevin Wiehe , Robert J Edwards , David Montefiori , Guido Ferrari , Ralph Baric , Derek W Cain , Kevin O Saunders , Barton F Haynes , Mihai L Azoitei

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein elicits antibodies targeting a membrane-proximal epitope.

Journal of virology

Avec: Ryan S McCool , Maryam Musayev , Sabrina M Bush , Alexandrine Derrien-Colemyn , Cory M Acreman , Daniel Wrapp , Tracy J Ruckwardt , Barney S Graham , John R Mascola , Jason S McLellan

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Cell

Avec: Daniel Wrapp , Dorien De Vlieger , Kizzmekia S Corbett , Gretel M Torres , Nianshuang Wang , Wander Van Breedam , Kenny Roose , Loes van Schie , Auteur inconnu , Markus Hoffmann , Stefan Pöhlmann , Barney S Graham , Nico Callewaert , Bert Schepens , Xavier Saelens , Jason S McLellan

Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.

bioRxiv : the preprint server for biology

Immunogenicity of a DNA vaccine candidate for COVID-19.

Nature communications

Avec: Trevor R F Smith , Ami Patel , Stephanie Ramos , Dustin Elwood , Xizhou Zhu , Jian Yan , Ebony N Gary , Susanne N Walker , Katherine Schultheis , Mansi Purwar , Ziyang Xu , Jewell Walters , Pratik Bhojnagarwala , Maria Yang , Neethu Chokkalingam , Patrick Pezzoli , Elizabeth Parzych , Emma L Reuschel , Arthur Doan , Nicholas Tursi , Miguel Vasquez , Jihae Choi , Edgar Tello-Ruiz , Igor Maricic , Mamadou A Bah , Yuanhan Wu , Dinah Amante , Daniel H Park , Yaya Dia , Ali Raza Ali , Faraz I Zaidi , Alison Generotti , Kevin Y Kim , Timothy A Herring , Sophia Reeder , Viviane M Andrade , Karen Buttigieg , Gan Zhao , Jiun-Ming Wu , Dan Li , Linlin Bao , Jiangning Liu , Wei Deng , Chuan Qin , Ami Shah Brown , Makan Khoshnejad , Nianshuang Wang , Jacqueline Chu , Daniel Wrapp , Jason S McLellan , Kar Muthumani , Bin Wang , Miles W Carroll , J Joseph Kim , Jean Boyer , Daniel W Kulp , Laurent M P F Humeau , David B Weiner , Kate E Broderick

The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation.

Journal of virology

Avec: Daniel Wrapp , Jason S McLellan

Iterative screen optimization maximizes the efficiency of macromolecular crystallization.

Acta crystallographica. Section F, Structural biology communications

Avec: Harrison G Jones , Daniel Wrapp , Morgan S A Gilman , Michael B Battles , Nianshuang Wang , Sofia Sacerdote , Gwo Yu Chuang , Peter D Kwong , Jason S McLellan

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates.

Science translational medicine

Avec: Bryan E Jones , Patricia L Brown-Augsburger , Kizzmekia S Corbett , Kathryn Westendorf , Julian Davies , Thomas P Cujec , Christopher M Wiethoff , Jamie L Blackbourne , Beverly A Heinz , Denisa Foster , Richard E Higgs , Deepa Balasubramaniam , Lingshu Wang , Yi Zhang , Eun Sung Yang , Roza Bidshahri , Lucas Kraft , Yuri Hwang , Stefanie Žentelis , Kevin R Jepson , Rodrigo Goya , Maia A Smith , David W Collins , Samuel J Hinshaw , Sean A Tycho , Davide Pellacani , Ping Xiang , Krithika Muthuraman , Solmaz Sobhanifar , Marissa H Piper , Franz J Triana , Jorg Hendle , Anna Pustilnik , Andrew C Adams , Shawn J Berens , Ralph S Baric , David R Martinez , Robert W Cross , Thomas W Geisbert , Viktoriya Borisevich , Olubukola Abiona , Hayley M Belli , Maren de Vries , Adil Mohamed , Meike Dittmann , Marie I Samanovic , Mark J Mulligan , Jory A Goldsmith , Ching-Lin Hsieh , Nicole V Johnson , Daniel Wrapp , Jason S McLellan , Bryan C Barnhart , Barney S Graham , John R Mascola , Carl L Hansen , Ester Falconer

Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.

Immunity

Avec: Maryam Mukhamedova , Daniel Wrapp , Chen-Hsiang Shen , Morgan S A Gilman , Tracy J Ruckwardt , Chaim A Schramm , Larissa Ault , Lauren Chang , Alexandrine Derrien-Colemyn , Sarah A M Lucas , Amy Ransier , Samuel Darko , Emily Phung , Lingshu Wang , Yi Zhang , Scott A Rush , Bharat Madan , Guillaume B E Stewart-Jones , Pamela J Costner , LaSonji A Holman , Somia P Hickman , Nina M Berkowitz , Nicole A Doria-Rose , Kaitlyn M Morabito , Brandon J DeKosky , Martin R Gaudinski , Grace L Chen , Michelle C Crank , John Misasi , Nancy J Sullivan , Daniel C Douek , Peter D Kwong , Barney S Graham , Jason S McLellan , John R Mascola

Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions.

bioRxiv : the preprint server for biology

Avec: Andrea R Shiakolas , Kevin J Kramer , Daniel Wrapp , Simone I Richardson , Alexandra Schäfer , Steven Wall , Nianshuang Wang , Katarzyna Janowska , Kelsey A Pilewski , Rohit Venkat , Rob Parks , Nelia P Manamela , Nagarajan Raju , Emilee Friedman Fechter , Clinton M Holt , Naveenchandra Suryadevara , Rita E Chen , David R Martinez , Rachel S Nargi , Rachel E Sutton , Julie E Ledgerwood , Barney S Graham , Michael S Diamond , Barton F Haynes , Priyamvada Acharya , Robert H Carnahan , James E Crowe , Ralph S Baric , Lynn Morris , Jason S McLellan , Ivelin S Georgiev

A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.

Antibody therapeutics

Avec: Leike Li , Yankai Wen , Daniel Wrapp , Jongmin Jeong , Peng Zhao , Wei Xiong , Constance Lynn Atkins , Zhao Shan , Deng Hui , Jason S McLellan , Ningyan Zhang , Cynthia Ju , Zhiqiang An

A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing.

bioRxiv : the preprint server for biology

Avec: Joyce K Hwang , Daniel J Marston , Daniel Wrapp , Dapeng Li , Marina Tuyishime , Simon Brackenridge , Brianna Rhodes , Max Quastel , A Brenda Kapingidza , Jacob Gater , Austin Harner , Yunfei Wang , Wes Rountree , Guido Ferrari , Persephone Borrow , Andrew J McMichael , Geraldine M Gillespie , Barton F Haynes , Mihai L Azoitei

Discrimination of primary and chronic cytomegalovirus infection based on humoral immune profiles in pregnancy.

The Journal of clinical investigation

Avec: Andrew P Hederman , Christopher J Remmel , Shilpee Sharma , Harini Natarajan , Joshua A Weiner , Daniel Wrapp , Catherine Donner , Marie-Luce Delforge , Piera d'Angelo , Milena Furione , Chiara Fornara , Jason S McLellan , Daniele Lilleri , Arnaud Marchant , Margaret E Ackerman

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness.

bioRxiv : the preprint server for biology

Avec: Kizzmekia S Corbett , Darin Edwards , Sarah R Leist , Olubukola M Abiona , Seyhan Boyoglu-Barnum , Rebecca A Gillespie , Sunny Himansu , Alexandra Schäfer , Cynthia T Ziwawo , Anthony T DiPiazza , Kenneth H Dinnon , Sayda M Elbashir , Christine A Shaw , Angela Woods , Ethan J Fritch , David R Martinez , Kevin W Bock , Mahnaz Minai , Bianca M Nagata , Geoffrey B Hutchinson , Kapil Bahl , Dario Garcia-Dominguez , LingZhi Ma , Isabella Renzi , Wing-Pui Kong , Stephen D Schmidt , Lingshu Wang , Yi Zhang , Laura J Stevens , Emily Phung , Lauren A Chang , Rebecca J Loomis , Nedim Emil Altaras , Elisabeth Narayanan , Mihir Metkar , Vlad Presnyak , Catherine Liu , Mark K Louder , Wei Shi , Kwanyee Leung , Eun Sung Yang , Ande West , Kendra L Gully , Nianshuang Wang , Daniel Wrapp , Nicole A Doria-Rose , Guillaume Stewart-Jones , Hamilton Bennett , Martha C Nason , Tracy J Ruckwardt , Jason S McLellan , Mark R Denison , James D Chappell , Ian N Moore , Kaitlyn M Morabito , John R Mascola , Ralph S Baric , Andrea Carfi , Barney S Graham

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.

Science (New York, N.Y.)

Avec: Ching-Lin Hsieh , Jory A Goldsmith , Jeffrey M Schaub , Andrea M DiVenere , Hung-Che Kuo , Kamyab Javanmardi , Kevin C Le , Daniel Wrapp , Alison G Lee , Yutong Liu , Chia-Wei Chou , Patrick O Byrne , Christy K Hjorth , Nicole V Johnson , John Ludes-Meyers , Annalee W Nguyen , Juyeon Park , Nianshuang Wang , Dzifa Amengor , Jason J Lavinder , Gregory C Ippolito , Jennifer A Maynard , Ilya J Finkelstein , Jason S McLellan

Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection.

Virology

Avec: Matthew L Goodwin , Helen S Webster , Hsuan-Yuan Wang , Jennifer A Jenks , Cody S Nelson , Joshua J Tu , Jesse F Mangold , Sarah Valencia , Justin Pollara , Whitney Edwards , Jason S McLellan , Daniel Wrapp , Tong-Ming Fu , Ningyan Zhang , Daniel C Freed , Dai Wang , Zhiqiang An , Sallie R Permar

Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.

PLoS pathogens

Avec: Xiaohua Ye , Hang Su , Daniel Wrapp , Daniel C Freed , Fengsheng Li , Zihao Yuan , Aimin Tang , Leike Li , Zhiqiang Ku , Wei Xiong , Dabbu Jaijyan , Hua Zhu , Dai Wang , Jason S McLellan , Ningyan Zhang , Tong-Ming Fu , Zhiqiang An

Prolonged evolution of the human B cell response to SARS-CoV-2 infection.

Science immunology

Avec: Mrunal Sakharkar , C Garrett Rappazzo , Wendy F Wieland-Alter , Ching-Lin Hsieh , Daniel Wrapp , Emma S Esterman , Chengzi I Kaku , Anna Z Wec , James C Geoghegan , Jason S McLellan , Ruth I Connor , Peter F Wright , Laura M Walker

Local computational methods to improve the interpretability and analysis of cryo-EM maps.

Nature communications

Avec: Satinder Kaur , Josue Gomez-Blanco , Ahmad A Z Khalifa , Swathi Adinarayanan , Ruben Sanchez-Garcia , Daniel Wrapp , Jason S McLellan , Khanh Huy Bui , Javier Vargas

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19.

bioRxiv : the preprint server for biology

Avec: C Garrett Rappazzo , Longping V Tse , Chengzi I Kaku , Daniel Wrapp , Mrunal Sakharkar , Deli Huang , Laura M Deveau , Thomas J Yockachonis , Andrew S Herbert , Michael B Battles , Cecilia M O'Brien , Michael E Brown , James C Geoghegan , Jonathan Belk , Linghang Peng , Linlin Yang , Trevor D Scobey , Dennis R Burton , David Nemazee , John M Dye , James E Voss , Bronwyn M Gunn , Jason S McLellan , Ralph S Baric , Lisa E Gralinski , Laura M Walker

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection.

bioRxiv : the preprint server for biology

Avec: Bryan E Jones , Patricia L Brown-Augsburger , Kizzmekia S Corbett , Kathryn Westendorf , Julian Davies , Thomas P Cujec , Christopher M Wiethoff , Jamie L Blackbourne , Beverly A Heinz , Denisa Foster , Richard E Higgs , Deepa Balasubramaniam , Lingshu Wang , Roza Bidshahri , Lucas Kraft , Yuri Hwang , Stefanie Žentelis , Kevin R Jepson , Rodrigo Goya , Maia A Smith , David W Collins , Samuel J Hinshaw , Sean A Tycho , Davide Pellacani , Ping Xiang , Krithika Muthuraman , Solmaz Sobhanifar , Marissa H Piper , Franz J Triana , Jorg Hendle , Anna Pustilnik , Andrew C Adams , Shawn J Berens , Ralph S Baric , David R Martinez , Robert W Cross , Thomas W Geisbert , Viktoriya Borisevich , Olubukola Abiona , Hayley M Belli , Maren de Vries , Adil Mohamed , Meike Dittmann , Marie Samanovic , Mark J Mulligan , Jory A Goldsmith , Ching-Lin Hsieh , Nicole V Johnson , Daniel Wrapp , Jason S McLellan , Bryan C Barnhart , Barney S Graham , John R Mascola , Carl L Hansen , Ester Falconer

Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody.

Science (New York, N.Y.)

Avec: C Garrett Rappazzo , Longping V Tse , Chengzi I Kaku , Daniel Wrapp , Mrunal Sakharkar , Deli Huang , Laura M Deveau , Thomas J Yockachonis , Andrew S Herbert , Michael B Battles , Cecilia M O'Brien , Michael E Brown , James C Geoghegan , Jonathan Belk , Linghang Peng , Linlin Yang , Yixuan Hou , Trevor D Scobey , Dennis R Burton , David Nemazee , John M Dye , James E Voss , Bronwyn M Gunn , Jason S McLellan , Ralph S Baric , Lisa E Gralinski , Laura M Walker

Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition.

Cell reports

Avec: Kevin J Kramer , Nicole V Johnson , Andrea R Shiakolas , Naveenchandra Suryadevara , Sivakumar Periasamy , Nagarajan Raju , Jazmean K Williams , Daniel Wrapp , Seth J Zost , Lauren M Walker , Steven C Wall , Clinton M Holt , Ching-Lin Hsieh , Rachel E Sutton , Ariana Paulo , Rachel S Nargi , Edgar Davidson , Benjamin J Doranz , James E Crowe , Alexander Bukreyev , Robert H Carnahan , Jason S McLellan , Ivelin S Georgiev

Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions.

Cell reports. Medicine

Avec: Andrea R Shiakolas , Kevin J Kramer , Daniel Wrapp , Simone I Richardson , Alexandra Schäfer , Steven Wall , Nianshuang Wang , Katarzyna Janowska , Kelsey A Pilewski , Rohit Venkat , Robert Parks , Nelia P Manamela , Nagarajan Raju , Emilee Friedman Fechter , Clinton M Holt , Naveenchandra Suryadevara , Rita E Chen , David R Martinez , Rachel S Nargi , Rachel E Sutton , Julie E Ledgerwood , Barney S Graham , Michael S Diamond , Barton F Haynes , Priyamvada Acharya , Robert H Carnahan , James E Crowe , Ralph S Baric , Lynn Morris , Jason S McLellan , Ivelin S Georgiev

Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.

Science advances

Avec: Daniel Wrapp , Xiaohua Ye , Zhiqiang Ku , Hang Su , Harrison G Jones , Nianshuang Wang , Akaash K Mishra , Daniel C Freed , Fengsheng Li , Aimin Tang , Leike Li , Dabbu Kumar Jaijyan , Hua Zhu , Dai Wang , Tong-Ming Fu , Ningyan Zhang , Zhiqiang An , Jason S McLellan

Structure-Based Stabilization of SOSIP Env Enhances Recombinant Ectodomain Durability and Yield.

Journal of virology

Avec: Daniel Wrapp , Zekun Mu , Bhishem Thakur , Katarzyna Janowska , Oluwatobi Ajayi , Maggie Barr , Robert Parks , Katayoun Mansouri , Robert J Edwards , Beatrice H Hahn , Priyamvada Acharya , Kevin O Saunders , Barton F Haynes

A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies.

mBio

Avec: Frederic Bibollet-Ruche , Ronnie M Russell , Wenge Ding , Weimin Liu , Yingying Li , Kshitij Wagh , Daniel Wrapp , Rumi Habib , Ashwin N Skelly , Ryan S Roark , Scott Sherrill-Mix , Shuyi Wang , Juliette Rando , Emily Lindemuth , Kendra Cruickshank , Younghoon Park , Rachel Baum , John W Carey , Andrew Jesse Connell , Hui Li , Elena E Giorgi , Ge S Song , Shilei Ding , Andrés Finzi , Amanda Newman , Giovanna E Hernandez , Emily Machiele , Derek W Cain , Katayoun Mansouri , Mark G Lewis , David C Montefiori , Kevin J Wiehe , S Munir Alam , I-Ting Teng , Peter D Kwong , Raiees Andrabi , Laurent Verkoczy , Dennis R Burton , Bette T Korber , Kevin O Saunders , Barton F Haynes , Robert J Edwards , George M Shaw , Beatrice H Hahn

Réseau de co-auteurs

Jason S McLellan 39 collaborations

Nianshuang Wang 17 collaborations

Barney S Graham 14 collaborations

Ching-Lin Hsieh 11 collaborations

Ralph S Baric 11 collaborations

Nicole V Johnson 9 collaborations

Kizzmekia S Corbett 7 collaborations

Barton F Haynes 7 collaborations

Jory A Goldsmith 6 collaborations

Mrunal Sakharkar 6 collaborations

Laura M Walker 6 collaborations

Alexandra Schäfer 6 collaborations

David R Martinez 6 collaborations

John R Mascola 6 collaborations

Olubukola Abiona 5 collaborations

Cecilia M O'Brien 5 collaborations

John M Dye 5 collaborations

Andrew S Herbert 5 collaborations

Dennis R Burton 5 collaborations

Ningyan Zhang 5 collaborations

Zhiqiang An 5 collaborations

Andrea R Shiakolas 5 collaborations

Kevin J Kramer 5 collaborations

Naveenchandra Suryadevara 5 collaborations

Nagarajan Raju 5 collaborations

Rachel E Sutton 5 collaborations

James E Crowe 5 collaborations

Robert H Carnahan 5 collaborations

Ivelin S Georgiev 5 collaborations

Lingshu Wang 5 collaborations

Anna Z Wec 4 collaborations

C Garrett Rappazzo 4 collaborations

Katayoun Mansouri 4 collaborations

Robert J Edwards 4 collaborations

Kevin O Saunders 4 collaborations

Deli Huang 4 collaborations

Longping V Tse 4 collaborations

David Nemazee 4 collaborations

James E Voss 4 collaborations

Kelsey A Pilewski 4 collaborations

Ande West 4 collaborations

Seyhan Boyoglu-Barnum 4 collaborations

Yi Zhang 4 collaborations

Tracy J Ruckwardt 4 collaborations

Denise Haslwanter 3 collaborations

M Eugenia Dieterle 3 collaborations

Catalina Florez 3 collaborations

Ariel S Wirchnianski 3 collaborations

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Rob Parks 3 collaborations

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Guido Ferrari 3 collaborations

Ralph Baric 3 collaborations

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Mihai L Azoitei 3 collaborations

Zhiqiang Ku 3 collaborations

Xiaohua Ye 3 collaborations

Hang Su 3 collaborations

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Alexander Bukreyev 3 collaborations

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Patrick Pezzoli 1 collaboration

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Dapeng Li 1 collaboration

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Darin Edwards 1 collaboration

Catherine Liu 1 collaboration

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Sarah Valencia 1 collaboration

Justin Pollara 1 collaboration

Whitney Edwards 1 collaboration

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Emma S Esterman 1 collaboration

Ruth I Connor 1 collaboration

Peter F Wright 1 collaboration

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Marie Samanovic 1 collaboration

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Jazmean K Williams 1 collaboration

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Ariana Paulo 1 collaboration

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Zekun Mu 1 collaboration

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Ronnie M Russell 1 collaboration

Wenge Ding 1 collaboration

Weimin Liu 1 collaboration

Yingying Li 1 collaboration

Kshitij Wagh 1 collaboration

Rumi Habib 1 collaboration

Ashwin N Skelly 1 collaboration

Ryan S Roark 1 collaboration

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Shuyi Wang 1 collaboration

Juliette Rando 1 collaboration

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Younghoon Park 1 collaboration

Rachel Baum 1 collaboration

John W Carey 1 collaboration

Andrew Jesse Connell 1 collaboration

Hui Li 1 collaboration

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Ge S Song 1 collaboration

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Giovanna E Hernandez 1 collaboration

Emily Machiele 1 collaboration

Mark G Lewis 1 collaboration

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George M Shaw 1 collaboration