Bruno Sepodes

Affiliations

Universidade de Lisboa, Faculdade de Farmácia, Lisbon, Portugal.

Publications (31)

The translational value of animal models in orphan medicines designations for rare paediatric neurological diseases.

Regulatory toxicology and pharmacology : RTP

Avec: Dinah M Duarte , Maria Beatriz da Silva Lima , Bruno Sepodes

Phenolic Compounds Impact on Rheumatoid Arthritis, Inflammatory Bowel Disease and Microbiota Modulation.

Pharmaceutics

Avec: Rosa Direito , João Rocha , Bruno Sepodes , Maria Eduardo-Figueira

Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: João Rocha , Rosa Direito , Ana Lima , Joana Mota , Margarida Gonçalves , Maria Paula Duarte , João Solas , Bruno Felício Peniche , Adelaide Fernandes , Rui Pinto , Ricardo Boavida Ferreira , Bruno Sepodes , Maria-Eduardo Figueira

Treatment Advances in Sepsis and Septic Shock: Modulating Pro- and Anti-Inflammatory Mechanisms.

Journal of clinical medicine

Avec: Adriana Marques , Carla Torre , Rui Pinto , Bruno Sepodes , João Rocha

Nonclinical data supporting orphan medicinal product designations in the area of rare infectious diseases.

Drug discovery today

Avec: Maria E Sheean , Eva Malikova , Dinah Duarte , Giuseppe Capovilla , Laura Fregonese , Matthias P Hofer , Armando Magrelli , Segundo Mariz , Fernando Mendez-Hermida , Robert Nistico , Tim Leest , Nikolaos V Sipsas , Stelios Tsigkos , Dinko Vitezic , Kristina Larsson , Bruno Sepodes , Violeta Stoyanova-Beninska

Hurdles in gene therapy regulatory approval: a retrospective analysis of European Marketing Authorization Applications.

Drug discovery today

Avec: Marta Carvalho , Ana Paula Martins , Bruno Sepodes

Implementation and Access to Pre-exposure Prophylaxis for Human Immunodeficiency Virus by Men Who Have Sex With Men in Europe.

Frontiers in medicine

Avec: Bruno Sepodes , João Rocha , Jorge Batista , Maria-Eduardo Figueira , František Dráfi , Carla Torre

Tumor Mutational Burden in Colorectal Cancer: Implications for Treatment.

Critical reviews in oncology/hematology

Avec: Adriana Marques , Patrícia Cavaco , Carla Torre , Bruno Sepodes , João Rocha

Trends in orphan medicinal products approvals in the European Union between 2010-2022.

Orphanet journal of rare diseases

Avec: Luísa Bouwman , Bruno Sepodes , Hubert Leufkens , Carla Torre

Plant-Derived Bioactive Compounds: Exploring Neuroprotective, Metabolic, and Hepatoprotective Effects for Health Promotion and Disease Prevention.

Pharmaceutics

Avec: Rosa Direito , Sandra Maria Barbalho , Bruno Sepodes , Maria Eduardo Figueira

Are Novel, Nonrandomized Analytic Methods Fit for Decision Making? The Need for Prospective, Controlled, and Transparent Validation.

Clinical pharmacology and therapeutics

Avec: Hans-Georg Eichler , Franz Koenig , Peter Arlett , Harald Enzmann , Anthony Humphreys , Frank Pétavy , Brigitte Schwarzer-Daum , Bruno Sepodes , Spiros Vamvakas , Guido Rasi

Anti-inflammatory Effects of Persimmon (

Journal of dietary supplements

Avec: Rosa Direito , João Rocha , Ana-Teresa Serra , Adelaide Fernandes , Marisa Freitas , Eduarda Fernandes , Rui Pinto , Rosário Bronze , Bruno Sepodes , Maria-Eduardo Figueira

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Nutrients

Avec: Rosa Direito , João Rocha , Bruno Sepodes , Maria Eduardo-Figueira

Inclusion of functional measures and frailty in the development and evaluation of medicines for older adults.

The lancet. Healthy longevity

Avec: Michael Denkinger , Wilma Knol , Antonio Cherubini , Anita Simonds , Christos Lionis , Denis Lacombe , Elena Petelos , Mary McCarthy , Patrick Ouvrard , Philip Van Kerrebroeck , Piotr Szymański , Amelia Cupelli , Andrea Laslop , Armin Koch , Bruno Sepodes , Carla Torre , Elina Rönnemaa , Ewa Bałkowiec-Iskra , Maria Teresa Herdeiro , Mário Miguel Rosa , Martine Trauffler , Nikica Mirošević Skvrce , Sabine Mayrhofer , Michael Berntgen , Ivana Silva , Francesca Cerreta

A cross-country utilization patterns comparison of high expenditure therapeutic groups between Portugal and six European countries: the two sides of the Portuguese coin.

Expert review of pharmacoeconomics & outcomes research

Avec: Inês Martinho , António Teixeira Rodrigues , José Guerreiro , João Rocha , Bruno Sepodes , Carla Torre

Comparative Analysis of Post-Authorization Measures for Advanced Medicinal Products Authorized in the European Union and in the United States of America Between 2009 and 2023.

Clinical pharmacology and therapeutics

Avec: Diana Mandslay , Diogo Almeida , Adriana Marques , João Rocha , Frantisek Drafi , Bruno Sepodes , Carla Torre

Clinical Trials for COVID-19: Can we Better Use the Short Window of Opportunity?

Clinical pharmacology and therapeutics

Avec: Hans-Georg Eichler , Marco Cavaleri , Harald Enzmann , Francesca Scotti , Bruno Sepodes , Fergus Sweeney , Spiros Vamvakas , Guido Rasi

Phytosomes with Persimmon (

Pharmaceutics

Avec: Rosa Direito , Catarina Reis , Luís Roque , Margarida Gonçalves , Ana Sanches-Silva , Maria Manuela Gaspar , Rui Pinto , João Rocha , Bruno Sepodes , Maria Rosário Bronze , Maria Eduardo Figueira

A proposed lectin-mediated mechanism to explain the in Vivo antihyperglycemic activity of γ-conglutin from

Food science & nutrition

Avec: Madalena Grácio , João Rocha , Rui Pinto , Ricardo Boavida Ferreira , João Solas , Maria Eduardo-Figueira , Bruno Sepodes , Ana Cristina Ribeiro

Spiro-β-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium.

ACS infectious diseases

Avec: Inês Bártolo , Bruna S Santos , Diana Fontinha , Marta Machado , Denise Francisco , Bruno Sepodes , João Rocha , Hélder Mota-Filipe , Rui Pinto , Maria E Figueira , Helena Barroso , Teresa Nascimento , António P Alves de Matos , Américo J S Alves , Nuno G Alves , Carlos J V Simões , Miguel Prudêncio , Teresa M V D Pinho E Melo , Nuno Taveira

Ebola outbreaks: A stress test of the preparedness of medicines regulatory systems for public health crises.

Drug discovery today

Avec: Rafael Amaral , Carla Torre , João Rocha , Bruno Sepodes

A review of the continuous professional development system for pharmacists.

Human resources for health

Avec: Jorge P B Batista , Carla Torre , José Manuel Sousa Lobo , Bruno Sepodes

Identification of Antibiotics in Surface-Groundwater. A Tool towards the Ecopharmacovigilance Approach: A Portuguese Case-Study.

Antibiotics (Basel, Switzerland)

Avec: Paula Viana , Leonor Meisel , Ana Lopes , Rosário de Jesus , Georgina Sarmento , Sofia Duarte , Bruno Sepodes , Ana Fernandes , Margarida M Correia Dos Santos , Anabela Almeida , M Conceição Oliveira

International journal of molecular sciences

Avec: Joana Mota , Rosa Direito , João Rocha , João Fernandes , Bruno Sepodes , Maria Eduardo Figueira , Anabela Raymundo , Ana Lima , Ricardo Boavida Ferreira

A review of patient-reported outcomes used for regulatory approval of oncology medicinal products in the European Union between 2017 and 2020.

Frontiers in medicine

Avec: Maria Manuel Teixeira , Fábio Cardoso Borges , Paula Sousa Ferreira , João Rocha , Bruno Sepodes , Carla Torre

Trends from two decades of orphan designations in paediatric rare neuromuscular diseases.

Journal of the neurological sciences

Avec: Dinah M Duarte , Maria Beatriz da Silva Lima , Bruno Sepodes

Medicines for an aging population: The EMA perspective and policies.

Journal of the American Geriatrics Society

Avec: Francesca Cerreta , Ewa Balkowiec Iskra , Amelia Cupelli , Bruno Sepodes , Elina Rönnemaa , Mário Miguel Rosa , Sabine Mayrhofer , Martine Trauffler , Carla Torre , Michael Berntgen , Katarina Vucic , Priya Bahri , Armin Koch , Maria Teresa Herdeiro , Nikica Mirošević Skvrce , Julia Pallos , Andrea Laslop

COVID-19 pandemic and the quality of antibiotic use in primary care: an interrupted time-series study.

International journal for quality in health care : journal of the International Society for Quality in Health Care

Avec: Mariana Domingues , Carla Torre , José Pedro Guerreiro , Pedro Barata , Margarida Correia-Neves , João Rocha , Bruno Sepodes , António Teixeira Rodrigues

Leveraging patient experience data to guide medicines development, regulation, access decisions and clinical care in the EU.

Frontiers in medicine

Avec: Diogo Almeida , Denise Umuhire , Rosa Gonzalez-Quevedo , Ana António , Juan Garcia Burgos , Patrice Verpillat , Nathalie Bere , Bruno Sepodes , Carla Torre

COVID-19 pandemic and the consumption of self-care products for pediculosis capitis in Portugal: an interrupted time-series analysis.

Parasitology research

Avec: Diogo Almeida , Antonio Teixeira Rodrigues , Jose Pedro Guerreiro , Ewa Bałkowiec-Iskra , Robert Vander Stichele , Bruno Sepodes , Carla Torre

Optimization of HPV-positive women triage with p16/Ki67 dual staining cytology in an organized cervical cancer screening program in the center region of Portugal.

European journal of obstetrics, gynecology, and reproductive biology

Avec: Bárbara Sepodes , Teresa Rebelo , Fernanda Santos , Duarte Oliveira , Carlos Catalão , Fernanda Águas , Graça Fernandes

Réseau de co-auteurs

João Rocha 16 collaborations

Carla Torre 14 collaborations

Rosa Direito 7 collaborations

Rui Pinto 6 collaborations

Maria Eduardo-Figueira 3 collaborations

Ricardo Boavida Ferreira 3 collaborations

Maria-Eduardo Figueira 3 collaborations

Adriana Marques 3 collaborations

Maria Eduardo Figueira 3 collaborations

Diogo Almeida 3 collaborations

Dinah M Duarte 2 collaborations

Maria Beatriz da Silva Lima 2 collaborations

Ana Lima 2 collaborations

Joana Mota 2 collaborations

Margarida Gonçalves 2 collaborations

João Solas 2 collaborations

Adelaide Fernandes 2 collaborations

Hans-Georg Eichler 2 collaborations

Harald Enzmann 2 collaborations

Spiros Vamvakas 2 collaborations

Guido Rasi 2 collaborations

Amelia Cupelli 2 collaborations

Andrea Laslop 2 collaborations

Armin Koch 2 collaborations

Elina Rönnemaa 2 collaborations

Ewa Bałkowiec-Iskra 2 collaborations

Maria Teresa Herdeiro 2 collaborations

Mário Miguel Rosa 2 collaborations

Martine Trauffler 2 collaborations

Nikica Mirošević Skvrce 2 collaborations

Sabine Mayrhofer 2 collaborations

Michael Berntgen 2 collaborations

Francesca Cerreta 2 collaborations

António Teixeira Rodrigues 2 collaborations

Maria Paula Duarte 1 collaboration

Bruno Felício Peniche 1 collaboration

Maria E Sheean 1 collaboration

Eva Malikova 1 collaboration

Dinah Duarte 1 collaboration

Giuseppe Capovilla 1 collaboration

Laura Fregonese 1 collaboration

Matthias P Hofer 1 collaboration

Armando Magrelli 1 collaboration

Segundo Mariz 1 collaboration

Fernando Mendez-Hermida 1 collaboration

Robert Nistico 1 collaboration

Tim Leest 1 collaboration

Nikolaos V Sipsas 1 collaboration

Stelios Tsigkos 1 collaboration

Dinko Vitezic 1 collaboration

Kristina Larsson 1 collaboration

Violeta Stoyanova-Beninska 1 collaboration

Marta Carvalho 1 collaboration

Ana Paula Martins 1 collaboration

Jorge Batista 1 collaboration

František Dráfi 1 collaboration

Patrícia Cavaco 1 collaboration

Luísa Bouwman 1 collaboration

Hubert Leufkens 1 collaboration

Sandra Maria Barbalho 1 collaboration

Franz Koenig 1 collaboration

Peter Arlett 1 collaboration

Anthony Humphreys 1 collaboration

Frank Pétavy 1 collaboration

Brigitte Schwarzer-Daum 1 collaboration

Ana-Teresa Serra 1 collaboration

Marisa Freitas 1 collaboration

Eduarda Fernandes 1 collaboration

Rosário Bronze 1 collaboration

Michael Denkinger 1 collaboration

Wilma Knol 1 collaboration

Antonio Cherubini 1 collaboration

Anita Simonds 1 collaboration

Christos Lionis 1 collaboration

Denis Lacombe 1 collaboration

Elena Petelos 1 collaboration

Mary McCarthy 1 collaboration

Patrick Ouvrard 1 collaboration

Philip Van Kerrebroeck 1 collaboration

Piotr Szymański 1 collaboration

Ivana Silva 1 collaboration

Inês Martinho 1 collaboration

José Guerreiro 1 collaboration

Diana Mandslay 1 collaboration

Frantisek Drafi 1 collaboration

Marco Cavaleri 1 collaboration

Francesca Scotti 1 collaboration

Fergus Sweeney 1 collaboration

Catarina Reis 1 collaboration

Luís Roque 1 collaboration

Ana Sanches-Silva 1 collaboration

Maria Manuela Gaspar 1 collaboration

Maria Rosário Bronze 1 collaboration

Madalena Grácio 1 collaboration

Ana Cristina Ribeiro 1 collaboration

Inês Bártolo 1 collaboration

Bruna S Santos 1 collaboration

Diana Fontinha 1 collaboration

Marta Machado 1 collaboration

Denise Francisco 1 collaboration

Hélder Mota-Filipe 1 collaboration

Maria E Figueira 1 collaboration

Helena Barroso 1 collaboration

Teresa Nascimento 1 collaboration

António P Alves de Matos 1 collaboration

Américo J S Alves 1 collaboration

Nuno G Alves 1 collaboration

Carlos J V Simões 1 collaboration

Miguel Prudêncio 1 collaboration

Teresa M V D Pinho E Melo 1 collaboration

Nuno Taveira 1 collaboration

Rafael Amaral 1 collaboration

Jorge P B Batista 1 collaboration

José Manuel Sousa Lobo 1 collaboration

Paula Viana 1 collaboration

Leonor Meisel 1 collaboration

Ana Lopes 1 collaboration

Rosário de Jesus 1 collaboration

Georgina Sarmento 1 collaboration

Sofia Duarte 1 collaboration

Ana Fernandes 1 collaboration

Margarida M Correia Dos Santos 1 collaboration

Anabela Almeida 1 collaboration

M Conceição Oliveira 1 collaboration

João Fernandes 1 collaboration

Anabela Raymundo 1 collaboration

Maria Manuel Teixeira 1 collaboration

Fábio Cardoso Borges 1 collaboration

Paula Sousa Ferreira 1 collaboration

Ewa Balkowiec Iskra 1 collaboration

Katarina Vucic 1 collaboration

Priya Bahri 1 collaboration

Julia Pallos 1 collaboration

Mariana Domingues 1 collaboration

José Pedro Guerreiro 1 collaboration

Pedro Barata 1 collaboration

Margarida Correia-Neves 1 collaboration

Denise Umuhire 1 collaboration

Rosa Gonzalez-Quevedo 1 collaboration

Ana António 1 collaboration

Juan Garcia Burgos 1 collaboration

Patrice Verpillat 1 collaboration

Nathalie Bere 1 collaboration

Antonio Teixeira Rodrigues 1 collaboration

Jose Pedro Guerreiro 1 collaboration

Robert Vander Stichele 1 collaboration

Bárbara Sepodes 1 collaboration

Teresa Rebelo 1 collaboration

Fernanda Santos 1 collaboration

Duarte Oliveira 1 collaboration

Carlos Catalão 1 collaboration

Fernanda Águas 1 collaboration

Graça Fernandes 1 collaboration