Bryan A Copits

Affiliations

Washington University Pain Center, Department of Anesthesiology, Washington University School of Medicine; St. Louis, MO.

Publications (22)

Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems.

bioRxiv : the preprint server for biology

Avec: Jamie C Moffa , India N Bland , Jessica R Tooley , Vani Kalyanaraman , Monique Heitmeier , Meaghan C Creed , Bryan A Copits

Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala.

eLife

Avec: Vijay K Samineni , Jose G Grajales-Reyes , Gary E Grajales-Reyes , Eric Tycksen , Bryan A Copits , Christian Pedersen , Edem S Ankudey , Julian N Sackey , Sienna B Sewell , Michael R Bruchas , Robert W Gereau

A wireless closed-loop system for optogenetic peripheral neuromodulation.

Nature

Avec: Aaron D Mickle , Sang Min Won , Kyung Nim Noh , Jangyeol Yoon , Kathleen W Meacham , Yeguang Xue , Lisa A McIlvried , Bryan A Copits , Vijay K Samineni , Kaitlyn E Crawford , Do Hoon Kim , Paulome Srivastava , Bong Hoon Kim , Seunghwan Min , Young Shiuan , Yeojeong Yun , Maria A Payne , Jianpeng Zhang , Hokyung Jang , Yuhang Li , H Henry Lai , Yonggang Huang , Sung-Il Park , Robert W Gereau , John A Rogers

A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits.

Nature methods

Avec: Jonas Wietek , Adrianna Nozownik , Mauro Pulin , Inbar Saraf-Sinik , Noa Matosevich , Raajaram Gowrishankar , Asaf Gat , Daniela Malan , Bobbie J Brown , Julien Dine , Bibi Nusreen Imambocus , Rivka Levy , Kathrin Sauter , Anna Litvin , Noa Regev , Suraj Subramaniam , Khalid Abrera , Dustin Summarli , Eva Madeline Goren , Gili Mizrachi , Eyal Bitton , Asaf Benjamin , Bryan A Copits , Philipp Sasse , Benjamin R Rost , Dietmar Schmitz , Michael R Bruchas , Peter Soba , Meital Oren-Suissa , Yuval Nir , J Simon Wiegert , Ofer Yizhar

Oral oxycodone self-administration leads to features of opioid misuse in male and female mice.

Addiction biology

Avec: Richard A Slivicki , Tom Earnest , Yu-Hsuan Chang , Rajesh Pareta , Eric Casey , Jun-Nan Li , Jessica Tooley , Kavitha Abiraman , Yvan M Vachez , Drew K Wolf , Jason T Sackey , Dhinesh Kumar Pitchai , Terrill Moore , Robert W Gereau , Bryan A Copits , Alexxai V Kravitz , Meaghan C Creed

Pain-Induced Negative Affect Is Mediated via Recruitment of The Nucleus Accumbens Kappa Opioid System.

Neuron

Avec: Nicolas Massaly , Bryan A Copits , Adrianne R Wilson-Poe , Lucia Hipólito , Tamara Markovic , Hye Jean Yoon , Shiwei Liu , Marie C Walicki , Dionnet L Bhatti , Sunil Sirohi , Amanda Klaas , Brendan M Walker , Rachael Neve , Catherine M Cahill , Kooresh I Shoghi , Robert W Gereau , Jordan G McCall , Ream Al-Hasani , Michael R Bruchas , Jose A Morón

A Paranigral VTA Nociceptin Circuit that Constrains Motivation for Reward.

Cell

Avec: Kyle E Parker , Christian E Pedersen , Adrian M Gomez , Skylar M Spangler , Marie C Walicki , Shelley Y Feng , Sarah L Stewart , James M Otis , Ream Al-Hasani , Jordan G McCall , Kristina Sakers , Dionnet L Bhatti , Bryan A Copits , Robert W Gereau , Thomas Jhou , Thomas J Kash , Joseph D Dougherty , Garret D Stuber , Michael R Bruchas

A photoswitchable GPCR-based opsin for presynaptic inhibition.

Neuron

Avec: Bryan A Copits , Raaj Gowrishankar , Patrick R O'Neill , Jun-Nan Li , Kasey S Girven , Judy J Yoo , Xenia Meshik , Kyle E Parker , Skylar M Spangler , Abigail J Elerding , Bobbie J Brown , Sofia E Shirley , Kelly K L Ma , Alexis M Vasquez , M Christine Stander , Vani Kalyanaraman , Sherri K Vogt , Vijay K Samineni , Tommaso Patriarchi , Lin Tian , N Gautam , Roger K Sunahara , Robert W Gereau , Michael R Bruchas

A central alarm system that gates multi-sensory innate threat cues to the amygdala.

Cell reports

Avec: Sukjae J Kang , Shijia Liu , Mao Ye , Dong-Il Kim , Gerald M Pao , Bryan A Copits , Benjamin Z Roberts , Kuo-Fen Lee , Michael R Bruchas , Sung Han

Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons.

bioRxiv : the preprint server for biology

Avec: Lisa A McIlvried , John Smith Del Rosario , Melanie Y Pullen , Andi Wangzhou , Tayler D Sheahan , Andrew J Shepherd , Richard A Slivicki , John A Lemen , Theodore J Price , Bryan A Copits , Robert W Gereau

Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia.

Science advances

Avec: Shamsuddin A Bhuiyan , Mengyi Xu , Lite Yang , Evangelia Semizoglou , Parth Bhatia , Katerina I Pantaleo , Ivan Tochitsky , Aakanksha Jain , Burcu Erdogan , Steven Blair , Victor Cat , Juliet M Mwirigi , Ishwarya Sankaranarayanan , Diana Tavares-Ferreira , Ursula Green , Lisa A McIlvried , Bryan A Copits , Zachariah Bertels , John S Del Rosario , Allie J Widman , Richard A Slivicki , Jiwon Yi , Reza Sharif-Naeini , Clifford J Woolf , Jochen K Lennerz , Jessica L Whited , Theodore J Price , Robert W Gereau Iv , William Renthal

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons.

Pain

Avec: Jiwon Yi , Zachariah Bertels , John Smith Del Rosario , Allie J Widman , Richard A Slivicki , Maria Payne , Henry M Susser , Bryan A Copits , Robert W Gereau

Distinct cellular expression and subcellular localization of Kv2 voltage-gated K

bioRxiv : the preprint server for biology

Avec: Robert G Stewart , Miriam Camacena , Bryan A Copits , Jon T Sack

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons.

bioRxiv : the preprint server for biology

Avec: Jiwon Yi , Zachariah Bertels , John Smith Del Rosario , Allie J Widman , Richard A Slivicki , Maria Payne , Henry M Susser , Bryan A Copits , Robert W Gereau

A bistable inhibitory OptoGPCR for multiplexed optogenetic control of neural circuits.

bioRxiv : the preprint server for biology

Avec: Jonas Wietek , Adrianna Nozownik , Mauro Pulin , Inbar Saraf-Sinik , Noa Matosevich , Daniela Malan , Bobbie J Brown , Julien Dine , Rivka Levy , Anna Litvin , Noa Regev , Suraj Subramaniam , Eyal Bitton , Asaf Benjamin , Bryan A Copits , Philipp Sasse , Benjamin R Rost , Dietmar Schmitz , Peter Soba , Yuval Nir , J Simon Wiegert , Ofer Yizhar

AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration.

bioRxiv : the preprint server for biology

Avec: Waruna Thotamune , Sithurandi Ubeysinghe , Chathuri Rajarathna , Dinesh Kankanamge , Koshala Olupothage , Aditya Chandu , Bryan A Copits , Ajith Karunarathne

Surgical implantation of wireless, battery-free optoelectronic epidural implants for optogenetic manipulation of spinal cord circuits in mice.

Nature protocols

Avec: Jose G Grajales-Reyes , Bryan A Copits , Ferrona Lie , Yongjoon Yu , Raudel Avila , Sherri K Vogt , Yonggang Huang , Anthony R Banks , John A Rogers , Robert W Gereau , Judith P Golden

Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors.

Science translational medicine

Avec: Diana Tavares-Ferreira , Stephanie Shiers , Pradipta R Ray , Andi Wangzhou , Vivekanand Jeevakumar , Ishwarya Sankaranarayanan , Anna M Cervantes , Jeffrey C Reese , Alexander Chamessian , Bryan A Copits , Patrick M Dougherty , Robert W Gereau , Michael D Burton , Gregory Dussor , Theodore J Price

Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia.

bioRxiv : the preprint server for biology

Avec: Shamsuddin A Bhuiyan , Mengyi Xu , Lite Yang , Evangelia Semizoglou , Parth Bhatia , Katerina I Pantaleo , Ivan Tochitsky , Aakanksha Jain , Burcu Erdogan , Steven Blair , Victor Cat , Juliet M Mwirigi , Ishwarya Sankaranarayanan , Diana Tavares-Ferreira , Ursula Green , Lisa A McIlvried , Bryan A Copits , Zachariah Bertels , John S Del Rosario , Allie J Widman , Richard A Slivicki , Jiwon Yi , Clifford J Woolf , Jochen K Lennerz , Jessica L Whited , Theodore J Price , Robert W Gereau , William Renthal

Wireless, Battery-Free Implants for Electrochemical Catecholamine Sensing and Optogenetic Stimulation.

ACS nano

Avec: Tucker Stuart , William J Jeang , Richard A Slivicki , Bobbie J Brown , Alex Burton , Victoria E Brings , Lilian C Alarcón-Segovia , Prophecy Agyare , Savanna Ruiz , Amanda Tyree , Lindsay Pruitt , Surabhi Madhvapathy , Martin Niemiec , James Zhuang , Siddharth Krishnan , Bryan A Copits , John A Rogers , Robert W Gereau , Vijay K Samineni , Amay J Bandodkar , Philipp Gutruf

Distinct cellular expression and subcellular localization of Kv2 voltage-gated K

The Journal of comparative neurology

Avec: Robert G Stewart , Miriam Camacena , Bryan A Copits , Jon T Sack

Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems.

eNeuro

Avec: Jamie C Moffa , India N Bland , Jessica R Tooley , Vani Kalyanaraman , Monique Heitmeier , Meaghan C Creed , Bryan A Copits

Réseau de co-auteurs

Robert W Gereau 13 collaborations

Richard A Slivicki 7 collaborations

Michael R Bruchas 6 collaborations

Vijay K Samineni 4 collaborations

Lisa A McIlvried 4 collaborations

Bobbie J Brown 4 collaborations

Theodore J Price 4 collaborations

Zachariah Bertels 4 collaborations

Allie J Widman 4 collaborations

Jiwon Yi 4 collaborations

Vani Kalyanaraman 3 collaborations

Meaghan C Creed 3 collaborations

John A Rogers 3 collaborations

John Smith Del Rosario 3 collaborations

Ishwarya Sankaranarayanan 3 collaborations

Diana Tavares-Ferreira 3 collaborations

Jamie C Moffa 2 collaborations

India N Bland 2 collaborations

Jessica R Tooley 2 collaborations

Monique Heitmeier 2 collaborations

Jose G Grajales-Reyes 2 collaborations

Yonggang Huang 2 collaborations

Jonas Wietek 2 collaborations

Adrianna Nozownik 2 collaborations

Mauro Pulin 2 collaborations

Inbar Saraf-Sinik 2 collaborations

Noa Matosevich 2 collaborations

Daniela Malan 2 collaborations

Julien Dine 2 collaborations

Rivka Levy 2 collaborations

Anna Litvin 2 collaborations

Noa Regev 2 collaborations

Suraj Subramaniam 2 collaborations

Eyal Bitton 2 collaborations

Asaf Benjamin 2 collaborations

Philipp Sasse 2 collaborations

Benjamin R Rost 2 collaborations

Dietmar Schmitz 2 collaborations

Peter Soba 2 collaborations

Yuval Nir 2 collaborations

J Simon Wiegert 2 collaborations

Ofer Yizhar 2 collaborations

Jun-Nan Li 2 collaborations

Marie C Walicki 2 collaborations

Dionnet L Bhatti 2 collaborations

Jordan G McCall 2 collaborations

Ream Al-Hasani 2 collaborations

Kyle E Parker 2 collaborations

Skylar M Spangler 2 collaborations

Sherri K Vogt 2 collaborations

Andi Wangzhou 2 collaborations

Shamsuddin A Bhuiyan 2 collaborations

Mengyi Xu 2 collaborations

Lite Yang 2 collaborations

Evangelia Semizoglou 2 collaborations

Parth Bhatia 2 collaborations

Katerina I Pantaleo 2 collaborations

Ivan Tochitsky 2 collaborations

Aakanksha Jain 2 collaborations

Burcu Erdogan 2 collaborations

Steven Blair 2 collaborations

Victor Cat 2 collaborations

Juliet M Mwirigi 2 collaborations

Ursula Green 2 collaborations

John S Del Rosario 2 collaborations

Clifford J Woolf 2 collaborations

Jochen K Lennerz 2 collaborations

Jessica L Whited 2 collaborations

William Renthal 2 collaborations

Maria Payne 2 collaborations

Henry M Susser 2 collaborations

Robert G Stewart 2 collaborations

Miriam Camacena 2 collaborations

Jon T Sack 2 collaborations

Gary E Grajales-Reyes 1 collaboration

Eric Tycksen 1 collaboration

Christian Pedersen 1 collaboration

Edem S Ankudey 1 collaboration

Julian N Sackey 1 collaboration

Sienna B Sewell 1 collaboration

Aaron D Mickle 1 collaboration

Sang Min Won 1 collaboration

Kyung Nim Noh 1 collaboration

Jangyeol Yoon 1 collaboration

Kathleen W Meacham 1 collaboration

Yeguang Xue 1 collaboration

Kaitlyn E Crawford 1 collaboration

Do Hoon Kim 1 collaboration

Paulome Srivastava 1 collaboration

Bong Hoon Kim 1 collaboration

Seunghwan Min 1 collaboration

Young Shiuan 1 collaboration

Yeojeong Yun 1 collaboration

Maria A Payne 1 collaboration

Jianpeng Zhang 1 collaboration

Hokyung Jang 1 collaboration

Yuhang Li 1 collaboration

H Henry Lai 1 collaboration

Sung-Il Park 1 collaboration

Raajaram Gowrishankar 1 collaboration

Asaf Gat 1 collaboration

Bibi Nusreen Imambocus 1 collaboration

Kathrin Sauter 1 collaboration

Khalid Abrera 1 collaboration

Dustin Summarli 1 collaboration

Eva Madeline Goren 1 collaboration

Gili Mizrachi 1 collaboration

Meital Oren-Suissa 1 collaboration

Tom Earnest 1 collaboration

Yu-Hsuan Chang 1 collaboration

Rajesh Pareta 1 collaboration

Eric Casey 1 collaboration

Jessica Tooley 1 collaboration

Kavitha Abiraman 1 collaboration

Yvan M Vachez 1 collaboration

Drew K Wolf 1 collaboration

Jason T Sackey 1 collaboration

Dhinesh Kumar Pitchai 1 collaboration

Terrill Moore 1 collaboration

Alexxai V Kravitz 1 collaboration

Nicolas Massaly 1 collaboration

Adrianne R Wilson-Poe 1 collaboration

Lucia Hipólito 1 collaboration

Tamara Markovic 1 collaboration

Hye Jean Yoon 1 collaboration

Shiwei Liu 1 collaboration

Sunil Sirohi 1 collaboration

Amanda Klaas 1 collaboration

Brendan M Walker 1 collaboration

Rachael Neve 1 collaboration

Catherine M Cahill 1 collaboration

Kooresh I Shoghi 1 collaboration

Jose A Morón 1 collaboration

Christian E Pedersen 1 collaboration

Adrian M Gomez 1 collaboration

Shelley Y Feng 1 collaboration

Sarah L Stewart 1 collaboration

James M Otis 1 collaboration

Kristina Sakers 1 collaboration

Thomas Jhou 1 collaboration

Thomas J Kash 1 collaboration

Joseph D Dougherty 1 collaboration

Garret D Stuber 1 collaboration

Raaj Gowrishankar 1 collaboration

Patrick R O'Neill 1 collaboration

Kasey S Girven 1 collaboration

Judy J Yoo 1 collaboration

Xenia Meshik 1 collaboration

Abigail J Elerding 1 collaboration

Sofia E Shirley 1 collaboration

Kelly K L Ma 1 collaboration

Alexis M Vasquez 1 collaboration

M Christine Stander 1 collaboration

Tommaso Patriarchi 1 collaboration

Lin Tian 1 collaboration

N Gautam 1 collaboration

Roger K Sunahara 1 collaboration

Sukjae J Kang 1 collaboration

Shijia Liu 1 collaboration

Mao Ye 1 collaboration

Dong-Il Kim 1 collaboration

Gerald M Pao 1 collaboration

Benjamin Z Roberts 1 collaboration

Kuo-Fen Lee 1 collaboration

Sung Han 1 collaboration

Melanie Y Pullen 1 collaboration

Tayler D Sheahan 1 collaboration

Andrew J Shepherd 1 collaboration

John A Lemen 1 collaboration

Reza Sharif-Naeini 1 collaboration

None Robert W Gereau Iv 1 collaboration

Waruna Thotamune 1 collaboration

Sithurandi Ubeysinghe 1 collaboration

Chathuri Rajarathna 1 collaboration

Dinesh Kankanamge 1 collaboration

Koshala Olupothage 1 collaboration

Aditya Chandu 1 collaboration

Ajith Karunarathne 1 collaboration

Ferrona Lie 1 collaboration

Yongjoon Yu 1 collaboration

Raudel Avila 1 collaboration

Anthony R Banks 1 collaboration

Judith P Golden 1 collaboration

Stephanie Shiers 1 collaboration

Pradipta R Ray 1 collaboration

Vivekanand Jeevakumar 1 collaboration

Anna M Cervantes 1 collaboration

Jeffrey C Reese 1 collaboration

Alexander Chamessian 1 collaboration

Patrick M Dougherty 1 collaboration

Michael D Burton 1 collaboration

Gregory Dussor 1 collaboration

Tucker Stuart 1 collaboration

William J Jeang 1 collaboration

Alex Burton 1 collaboration

Victoria E Brings 1 collaboration

Lilian C Alarcón-Segovia 1 collaboration

Prophecy Agyare 1 collaboration

Savanna Ruiz 1 collaboration

Amanda Tyree 1 collaboration

Lindsay Pruitt 1 collaboration

Surabhi Madhvapathy 1 collaboration

Martin Niemiec 1 collaboration

James Zhuang 1 collaboration

Siddharth Krishnan 1 collaboration

Amay J Bandodkar 1 collaboration

Philipp Gutruf 1 collaboration