Christophe Deben

Affiliations

Center for Oncological Research (CORE), University of Antwerp, 2610 Wilrijk, Belgium.

ORCID: 0000-0001-8085-2040

Publications (28)

Radiosensitization of Non-Small Cell Lung Cancer Cells by the Plk1 Inhibitor Volasertib Is Dependent on the p53 Status.

Cancers

Avec: Jolien Van den Bossche , Andreas Domen , Marc Peeters , Christophe Deben , Ines De Pauw , Julie Jacobs , Sven De Bruycker , Pol Specenier , Patrick Pauwels , Jan Baptist Vermorken , Filip Lardon , An Wouters

Influence of Cell Type and Culture Medium on Determining Cancer Selectivity of Cold Atmospheric Plasma Treatment.

Cancers

Avec: Eline Biscop , Abraham Lin , Wilma Van Boxem , Jinthe Van Loenhout , Joey De Backer , Christophe Deben , Sylvia Dewilde , Evelien Smits , And Annemie Bogaerts

Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer.

NPJ precision oncology

Avec: Maxim Le Compte , Edgar Cardenas De La Hoz , Sofía Peeters , Felicia Rodrigues Fortes , Christophe Hermans , Andreas Domen , Evelien Smits , Filip Lardon , Timon Vandamme , Abraham Lin , Steve Vanlanduit , Geert Roeyen , Steven Van Laere , Hans Prenen , Marc Peeters , Christophe Deben

CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles.

Journal of translational medicine

Avec: Marc Terrones , Christophe Deben , Felicia Rodrigues-Fortes , Anne Schepers , Ken Op de Beeck , Guy Van Camp , Geert Vandeweyer

Oxidative Stress-Inducing Anticancer Therapies: Taking a Closer Look at Their Immunomodulating Effects.

Antioxidants (Basel, Switzerland)

Avec: Jinthe Van Loenhout , Marc Peeters , Annemie Bogaerts , Evelien Smits , Christophe Deben

Cellular senescence in cancer: clinical detection and prognostic implications.

Journal of experimental & clinical cancer research : CR

Avec: Andreas Domen , Christophe Deben , Jasper Verswyvel , Tal Flieswasser , Hans Prenen , Marc Peeters , Filip Lardon , An Wouters

IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.

Journal of hematology & oncology

Avec: Astrid Van den Eynde , Laura Gehrcken , Tias Verhezen , Ho Wa Lau , Christophe Hermans , Hilde Lambrechts , Tal Flieswasser , Delphine Quatannens , Gils Roex , Karen Zwaenepoel , Elly Marcq , Philippe Joye , Edgar Cardenas De La Hoz , Christophe Deben , Alessia Gasparini , Pierre Montay-Gruel , Maxim Le Compte , Eva Lion , Filip Lardon , Steven Van Laere , Vasiliki Siozopoulou , Diana Campillo-Davo , Jorrit De Waele , Patrick Pauwels , Julie Jacobs , Evelien Smits , Jonas R M Van Audenaerde

Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer.

Cancers

Avec: Andreas Domen , Delphine Quatannens , Sara Zanivan , Christophe Deben , Jonas Van Audenaerde , Evelien Smits , An Wouters , Filip Lardon , Geert Roeyen , Yannick Verhoeven , Annelies Janssens , Timon Vandamme , Peter van Dam , Marc Peeters , Hans Prenen

A Systematic Review of Patient-derived Tumor Organoids Generation from Malignant Effusions.

Critical reviews in oncology/hematology

Avec: Sofie Seghers , Maxim Le Compte , Jeroen M H Hendriks , Paul Van Schil , Annelies Janssens , Reinier Wener , Niels Komen , Hans Prenen , Christophe Deben

OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening.

Cellular oncology (Dordrecht)

Avec: Christophe Deben , Edgar Cardenas De La Hoz , Maxim Le Compte , Paul Van Schil , Jeroen M H Hendriks , Patrick Lauwers , Suresh Krishan Yogeswaran , Filip Lardon , Patrick Pauwels , Steven Van Laere , Annemie Bogaerts , Evelien Smits , Steve Vanlanduit , Abraham Lin

Multiparametric Tumor Organoid Drug Screening Using Widefield Live-Cell Imaging for Bulk and Single-Organoid Analysis.

Journal of visualized experiments : JoVE

Avec: Maxim Le Compte , Edgar Cardenas De La Hoz , Sofía Peeters , Evelien Smits , Filip Lardon , Geert Roeyen , Steve Vanlanduit , Hans Prenen , Marc Peeters , Abraham Lin , Christophe Deben

UAS™-A Urine Preservative for Oncology Applications.

Cancers

Avec: Stephanie Jordaens , Amit Arora , Kyle W MacDonald , Cameron Wood , Jhana O Hendrickx , Karen Zwaenepoel , Christophe Deben , Wiebren Tjalma , Patrick Pauwels , Koen Beyers , Vanessa Vankerckhoven

Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells.

Cancers

Avec: Jinthe Van Loenhout , Tal Flieswasser , Laurie Freire Boullosa , Jorrit De Waele , Jonas Van Audenaerde , Elly Marcq , Julie Jacobs , Abraham Lin , Eva Lion , Heleen Dewitte , Marc Peeters , Sylvia Dewilde , Filip Lardon , Annemie Bogaerts , Christophe Deben , Evelien Smits

Mass Spectrometry Imaging Reveals Neutrophil Defensins as Additional Biomarkers for Anti-PD-(L)1 Immunotherapy Response in NSCLC Patients.

Cancers

Avec: Eline Berghmans , Julie Jacobs , Christophe Deben , Christophe Hermans , Glenn Broeckx , Evelien Smits , Evelyne Maes , Jo Raskin , Patrick Pauwels , Geert Baggerman

Auranofin and Cold Atmospheric Plasma Synergize to Trigger Distinct Cell Death Mechanisms and Immunogenic Responses in Glioblastoma.

Cells

Avec: Jinthe Van Loenhout , Laurie Freire Boullosa , Delphine Quatannens , Jorrit De Waele , Céline Merlin , Hilde Lambrechts , Ho Wa Lau , Christophe Hermans , Abraham Lin , Filip Lardon , Marc Peeters , Annemie Bogaerts , Evelien Smits , Christophe Deben

Prognostic implications of cellular senescence in resected non-small cell lung cancer.

Translational lung cancer research

Avec: Andreas Domen , Christophe Deben , Ines De Pauw , Christophe Hermans , Hilde Lambrechts , Jasper Verswyvel , Vasiliki Siozopoulou , Patrick Pauwels , Marco Demaria , Mick van de Wiel , Annelies Janssens , Jeroen M H Hendriks , Paul Van Schil , Jan B Vermorken , Timon Vandamme , Hans Prenen , Marc Peeters , Filip Lardon , An Wouters

Auranofin Synergizes with the PARP Inhibitor Olaparib to Induce ROS-Mediated Cell Death in Mutant p53 Cancers.

Antioxidants (Basel, Switzerland)

Avec: Laurie Freire Boullosa , Jinthe Van Loenhout , Tal Flieswasser , Christophe Hermans , Céline Merlin , Ho Wa Lau , Elly Marcq , Marlies Verschuuren , Winnok H De Vos , Filip Lardon , Evelien L J Smits , Christophe Deben

Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods.

International journal of cancer

Avec: Stephanie Jordaens , Karen Zwaenepoel , Wiebren Tjalma , Christophe Deben , Koen Beyers , Vanessa Vankerckhoven , Patrick Pauwels , Alex Vorsters

Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition.

Journal of experimental & clinical cancer research : CR

Avec: Christophe Deben , Laurie Freire Boullosa , Felicia Rodrigues Fortes , Edgar Cardenas De La Hoz , Maxim Le Compte , Sofie Seghers , Marc Peeters , Steve Vanlanduit , Abraham Lin , Krijn K Dijkstra , Paul Van Schil , Jeroen M H Hendriks , Hans Prenen , Geert Roeyen , Filip Lardon , Evelien Smits

Advancements in Research and Treatment Applications of Patient-Derived Tumor Organoids in Colorectal Cancer.

Cancers

Avec: Denise van der Graaff , Sofie Seghers , Pieterjan Vanclooster , Christophe Deben , Timon Vandamme , Hans Prenen

Patient-derived organoids as individual patient models for chemoradiation response prediction in gastrointestinal malignancies.

Critical reviews in oncology/hematology

Avec: Maxim Le Compte , Niels Komen , Ines Joye , Marc Peeters , Hans Prenen , Evelien Smits , Christophe Deben , Michiel de Maat

Auranofin reveals therapeutic anticancer potential by triggering distinct molecular cell death mechanisms and innate immunity in mutant p53 non-small cell lung cancer.

Redox biology

Avec: Laurie Freire Boullosa , Jinthe Van Loenhout , Tal Flieswasser , Jorrit De Waele , Christophe Hermans , Hilde Lambrechts , Bart Cuypers , Kris Laukens , Esther Bartholomeus , Vasiliki Siozopoulou , Winnok H De Vos , Marc Peeters , Evelien L J Smits , Christophe Deben

The potential and controversy of targeting STAT family members in cancer.

Seminars in cancer biology

Avec: Yannick Verhoeven , Sam Tilborghs , Julie Jacobs , Jorrit De Waele , Delphine Quatannens , Christophe Deben , Hans Prenen , Patrick Pauwels , Xuan Bich Trinh , An Wouters , Evelien L J Smits , Filip Lardon , Peter A van Dam

In vitro study of the Polo-like kinase 1 inhibitor volasertib in non-small-cell lung cancer reveals a role for the tumor suppressor p53.

Molecular oncology

Avec: Jolien Van den Bossche , Christophe Deben , Ines De Pauw , Hilde Lambrechts , Christophe Hermans , Vanessa Deschoolmeester , Julie Jacobs , Pol Specenier , Patrick Pauwels , Jan Baptist Vermorken , Marc Peeters , Filip Lardon , An Wouters

Expression of SARS-CoV-2-Related Surface Proteins in Non-Small-Cell Lung Cancer Patients and the Influence of Standard of Care Therapy.

Cancers

Avec: Christophe Deben , Maxim Le Compte , Vasiliki Siozopoulou , Hilde Lambrechts , Christophe Hermans , Ho Wa Lau , Manon Huizing , Kevin Lamote , Jeroen M H Hendriks , Peter Van Dam , Patrick Pauwels , Evelien L J Smits , Marc Peeters , Filip Lardon

Functional Validation of the Putative Oncogenic Activity of

Biomedicines

Avec: Federica Sarno , Désirée Goubert , Emilie Logie , Martijn G S Rutten , Mihaly Koncz , Christophe Deben , Anita E Niemarkt , Lucia Altucci , Pernette J Verschure , Antal Kiss , Wim Vanden Berghe , Marianne G Rots

Optimization of the Solvent and In Vivo Administration Route of Auranofin in a Syngeneic Non-Small Cell Lung Cancer and Glioblastoma Mouse Model.

Pharmaceutics

Avec: Laurie Freire Boullosa , Jinthe Van Loenhout , Christophe Hermans , Ho Wa Lau , Céline Merlin , Elly Marcq , Farnaz Sedigheh Takhsha , Wim Martinet , Guido R Y De Meyer , Filip Lardon , Evelien L J Smits , Christophe Deben

"Keep on ROCKIn": Repurposed ROCK inhibitors to boost corneal endothelial regeneration.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Hendrik Vercammen , Martin Ondra , Jana Kotulova , Edgar Cardenas De La Hoz , Charissa Witters , Katerina Jecmenova , Maxim Le Compte , Christophe Deben , Sorcha Ní Dhubhghaill , Carina Koppen , Marián Hajdúch , Bert Van den Bogerd

Réseau de co-auteurs

Filip Lardon 16 collaborations

Marc Peeters 14 collaborations

Evelien Smits 12 collaborations

Patrick Pauwels 10 collaborations

Christophe Hermans 10 collaborations

Hans Prenen 10 collaborations

Maxim Le Compte 9 collaborations

Abraham Lin 7 collaborations

Jinthe Van Loenhout 7 collaborations

Julie Jacobs 6 collaborations

An Wouters 6 collaborations

Edgar Cardenas De La Hoz 6 collaborations

Hilde Lambrechts 6 collaborations

Laurie Freire Boullosa 6 collaborations

Andreas Domen 5 collaborations

Tal Flieswasser 5 collaborations

Ho Wa Lau 5 collaborations

Jorrit De Waele 5 collaborations

Jeroen M H Hendriks 5 collaborations

Evelien L J Smits 5 collaborations

Timon Vandamme 4 collaborations

Steve Vanlanduit 4 collaborations

Geert Roeyen 4 collaborations

Annemie Bogaerts 4 collaborations

Delphine Quatannens 4 collaborations

Elly Marcq 4 collaborations

Vasiliki Siozopoulou 4 collaborations

Paul Van Schil 4 collaborations

Ines De Pauw 3 collaborations

Steven Van Laere 3 collaborations

Karen Zwaenepoel 3 collaborations

Annelies Janssens 3 collaborations

Sofie Seghers 3 collaborations

Céline Merlin 3 collaborations

Jolien Van den Bossche 2 collaborations

Pol Specenier 2 collaborations

Jan Baptist Vermorken 2 collaborations

Sylvia Dewilde 2 collaborations

Sofía Peeters 2 collaborations

Felicia Rodrigues Fortes 2 collaborations

Jasper Verswyvel 2 collaborations

Eva Lion 2 collaborations

Jonas Van Audenaerde 2 collaborations

Yannick Verhoeven 2 collaborations

Niels Komen 2 collaborations

Stephanie Jordaens 2 collaborations

Wiebren Tjalma 2 collaborations

Koen Beyers 2 collaborations

Vanessa Vankerckhoven 2 collaborations

Winnok H De Vos 2 collaborations

Sven De Bruycker 1 collaboration

Eline Biscop 1 collaboration

Wilma Van Boxem 1 collaboration

Joey De Backer 1 collaboration

And Annemie Bogaerts 1 collaboration

Marc Terrones 1 collaboration

Felicia Rodrigues-Fortes 1 collaboration

Anne Schepers 1 collaboration

Ken Op de Beeck 1 collaboration

Guy Van Camp 1 collaboration

Geert Vandeweyer 1 collaboration

Astrid Van den Eynde 1 collaboration

Laura Gehrcken 1 collaboration

Tias Verhezen 1 collaboration

Gils Roex 1 collaboration

Philippe Joye 1 collaboration

Alessia Gasparini 1 collaboration

Pierre Montay-Gruel 1 collaboration

Diana Campillo-Davo 1 collaboration

Jonas R M Van Audenaerde 1 collaboration

Sara Zanivan 1 collaboration

Peter van Dam 1 collaboration

Reinier Wener 1 collaboration

Patrick Lauwers 1 collaboration

Suresh Krishan Yogeswaran 1 collaboration

Amit Arora 1 collaboration

Kyle W MacDonald 1 collaboration

Cameron Wood 1 collaboration

Jhana O Hendrickx 1 collaboration

Heleen Dewitte 1 collaboration

Eline Berghmans 1 collaboration

Glenn Broeckx 1 collaboration

Evelyne Maes 1 collaboration

Jo Raskin 1 collaboration

Geert Baggerman 1 collaboration

Marco Demaria 1 collaboration

Mick van de Wiel 1 collaboration

Jan B Vermorken 1 collaboration

Marlies Verschuuren 1 collaboration

Alex Vorsters 1 collaboration

Krijn K Dijkstra 1 collaboration

Denise van der Graaff 1 collaboration

Pieterjan Vanclooster 1 collaboration

Ines Joye 1 collaboration

Michiel de Maat 1 collaboration

Bart Cuypers 1 collaboration

Kris Laukens 1 collaboration

Esther Bartholomeus 1 collaboration

Sam Tilborghs 1 collaboration

Xuan Bich Trinh 1 collaboration

Peter A van Dam 1 collaboration

Vanessa Deschoolmeester 1 collaboration

Manon Huizing 1 collaboration

Kevin Lamote 1 collaboration

Peter Van Dam 1 collaboration

Federica Sarno 1 collaboration

Désirée Goubert 1 collaboration

Emilie Logie 1 collaboration

Martijn G S Rutten 1 collaboration

Mihaly Koncz 1 collaboration

Anita E Niemarkt 1 collaboration

Lucia Altucci 1 collaboration

Pernette J Verschure 1 collaboration

Antal Kiss 1 collaboration

Wim Vanden Berghe 1 collaboration

Marianne G Rots 1 collaboration

Farnaz Sedigheh Takhsha 1 collaboration

Wim Martinet 1 collaboration

Guido R Y De Meyer 1 collaboration

Hendrik Vercammen 1 collaboration

Martin Ondra 1 collaboration

Jana Kotulova 1 collaboration

Charissa Witters 1 collaboration

Katerina Jecmenova 1 collaboration

Sorcha Ní Dhubhghaill 1 collaboration

Carina Koppen 1 collaboration

Marián Hajdúch 1 collaboration

Bert Van den Bogerd 1 collaboration